Lyndon Jones

Summary

Affiliation: University of Waterloo
Country: Canada

Publications

  1. ncbi request reprint Extraction efficiency of an extraction buffer used to quantify lysozyme deposition on conventional and silicone hydrogel contact lens materials
    Lakshman N Subbaraman
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Eye Contact Lens 33:169-73. 2007
  2. doi request reprint Uptake and release phenomena in contact lens care by silicone hydrogel lenses
    Lyndon Jones
    Centre for Contact Lens Research L J, School of Optometry and Vision Science, University of Waterloo, Waterloo, Canada
    Eye Contact Lens 39:29-36. 2013
  3. ncbi request reprint Asymptomatic corneal staining associated with the use of balafilcon silicone-hydrogel contact lenses disinfected with a polyaminopropyl biguanide-preserved care regimen
    Lyndon Jones
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 79:753-61. 2002
  4. ncbi request reprint Lysozyme and lipid deposition on silicone hydrogel contact lens materials
    Lyndon Jones
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Canada
    Eye Contact Lens 29:S75-9; discussion S83-4, S192-4. 2003
  5. pmc MUC1 expression in Sjogren's syndrome, KCS, and control subjects
    Barbary Caffery
    Center for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada
    Mol Vis 16:1720-7. 2010
  6. pmc Quantification of MUCIN 1, cell surface associated and MUCIN16, cell surface associated proteins in tears and conjunctival epithelial cells collected from postmenopausal women
    Sruthi Srinivasan
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Mol Vis 19:970-9. 2013
  7. doi request reprint Ex vivo protein deposition on bi-weekly silicone hydrogel contact lenses
    Adrienne Boone
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 86:1241-9. 2009
  8. pmc The efficiency of contact lens care regimens on protein removal from hydrogel and silicone hydrogel lenses
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, ON, Canada
    Mol Vis 16:79-92. 2010
  9. ncbi request reprint Localization of lysozyme sorption to conventional and silicone hydrogel contact lenses using confocal microscopy
    Doerte Luensmann
    Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario, Canada
    Curr Eye Res 34:683-97. 2009
  10. ncbi request reprint Quantitative and conformational characterization of lysozyme deposited on balafilcon and etafilcon contact lens materials
    Michelle Senchyna
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Curr Eye Res 28:25-36. 2004

Collaborators

Detail Information

Publications88

  1. ncbi request reprint Extraction efficiency of an extraction buffer used to quantify lysozyme deposition on conventional and silicone hydrogel contact lens materials
    Lakshman N Subbaraman
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Eye Contact Lens 33:169-73. 2007
    ..The purpose of this study was to determine the efficiency of TFA/ACN in extracting lysozyme from silicone hydrogel and etafilcon lenses by using an in vitro model...
  2. doi request reprint Uptake and release phenomena in contact lens care by silicone hydrogel lenses
    Lyndon Jones
    Centre for Contact Lens Research L J, School of Optometry and Vision Science, University of Waterloo, Waterloo, Canada
    Eye Contact Lens 39:29-36. 2013
    ..It also reviews whether current methods to determine these interactions could be improved on...
  3. ncbi request reprint Asymptomatic corneal staining associated with the use of balafilcon silicone-hydrogel contact lenses disinfected with a polyaminopropyl biguanide-preserved care regimen
    Lyndon Jones
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 79:753-61. 2002
    ..To compare subjective symptoms and signs in a group of individuals who wear silicone-hydrogel lenses on a daily wear basis while they sequentially used two differing care regimens...
  4. ncbi request reprint Lysozyme and lipid deposition on silicone hydrogel contact lens materials
    Lyndon Jones
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Canada
    Eye Contact Lens 29:S75-9; discussion S83-4, S192-4. 2003
    ..We sought to determine whether there were differences in lysozyme (quantity and conformation) and lipid deposition on in vivo worn conventional (etafilcon) and silicone hydrogel (balafilcon and lotrafilcon) contact lenses...
  5. pmc MUC1 expression in Sjogren's syndrome, KCS, and control subjects
    Barbary Caffery
    Center for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada
    Mol Vis 16:1720-7. 2010
    ....
  6. pmc Quantification of MUCIN 1, cell surface associated and MUCIN16, cell surface associated proteins in tears and conjunctival epithelial cells collected from postmenopausal women
    Sruthi Srinivasan
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Mol Vis 19:970-9. 2013
    ....
  7. doi request reprint Ex vivo protein deposition on bi-weekly silicone hydrogel contact lenses
    Adrienne Boone
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 86:1241-9. 2009
    ..This study investigated the protein deposition that occurs on daily wear silicone hydrogel (SH) lenses, after 2 weeks of wear...
  8. pmc The efficiency of contact lens care regimens on protein removal from hydrogel and silicone hydrogel lenses
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, ON, Canada
    Mol Vis 16:79-92. 2010
    ....
  9. ncbi request reprint Localization of lysozyme sorption to conventional and silicone hydrogel contact lenses using confocal microscopy
    Doerte Luensmann
    Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario, Canada
    Curr Eye Res 34:683-97. 2009
    ..To investigate the distribution profile of hen egg lysozyme (HEL) through poly-2-hydroxyethyl methacrylate (pHEMA)-based lens materials and silicone hydrogel (SH) lens materials using confocal laser scanning microscopy (CLSM)...
  10. ncbi request reprint Quantitative and conformational characterization of lysozyme deposited on balafilcon and etafilcon contact lens materials
    Michelle Senchyna
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Curr Eye Res 28:25-36. 2004
    ..To determine whether differences in lysozyme deposition and/or activity exist on worn etafilcon and balafilcon contact lenses following care with a polyquaternium-based system (PQ) or a polyhexanide-based system (PHMB)...
  11. ncbi request reprint Rewetting drops containing surface active agents improve the clinical performance of silicone hydrogel contact lenses
    Lakshman N Subbaraman
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 83:143-51. 2006
    ....
  12. doi request reprint Determination of albumin sorption to intraocular lenses by radiolabeling and confocal laser scanning microscopy
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    J Cataract Refract Surg 35:2000-7. 2009
    ..To determine albumin adsorption profiles and penetration depth of 3 intraocular lens (IOL) materials over time using confocal laser scanning microscopy (CLSM) and radiolabeling...
  13. doi request reprint Impact of protein and lipid on neutralization times of hydrogen peroxide care regimens
    William Ngo
    Centre for Contact Lens Research, University of Waterloo, Ontario, Canada
    Eye Contact Lens 35:282-6. 2009
    ..To investigate the effect of protein, lipid, and lens material on the neutralization kinetics of one-step hydrogen peroxide disinfection systems...
  14. doi request reprint Tear lipocalin and lysozyme concentrations in postmenopausal women
    Sruthi Srinivasan
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada
    Ophthalmic Physiol Opt 30:257-66. 2010
    ....
  15. doi request reprint Impact of tear film components on the conformational state of lysozyme deposited on contact lenses
    Alan Ng
    Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada
    J Biomed Mater Res B Appl Biomater 101:1172-81. 2013
    ..To investigate the impact of lactoferrin and lipids on the kinetic denaturation of lysozyme deposited on silicone and conventional hydrogel lenses, using a complex artificial tear solution (ATS)...
  16. ncbi request reprint Optimization of a fluorescence-based lysozyme activity assay for contact lens studies
    Alan Ng
    Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada
    Curr Eye Res 38:252-9. 2013
    ....
  17. pmc Composition of incubation solution impacts in vitro protein uptake to silicone hydrogel contact lenses
    Salsabeel Jadi
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1
    Mol Vis 18:337-47. 2012
    ..To determine the impact of incubation solution composition on protein deposition to silicone hydrogel (SH) contact lenses using a simplistic and a complex model of the tear film...
  18. doi request reprint Clinical performance of different care systems with silicone hydrogel contact lenses
    Nancy Keir
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200 University Ave West, Waterloo, ON N2L3G1, Canada
    Cont Lens Anterior Eye 33:189-95. 2010
    ..To assess the clinical and subjective performance of a one-step hydrogen peroxide (H2O2) lens care system compared to a multi-purpose disinfecting system (MPDS) when used with silicone hydrogel (SiH) lenses...
  19. doi request reprint Compliance with contact lens replacement in Canada and the United States
    Kathryn Dumbleton
    Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 87:131-9. 2010
    ..S. and to compare noncompliance (NC) with manufacturer recommended RF by the ECP and patient, and the reasons given for NC...
  20. doi request reprint Conformational and quantitative characterization of lysozyme extracted from galyfilcon and senofilcon silicone hydrogel contact lenses
    Mary Ann Glasier
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Curr Eye Res 33:1-11. 2008
    ..To compare two solvents for retrieval of lysozyme deposited on a silicone hydrogel (SH) contact lens material galyfilcon A (GA; Acuvue Advance)...
  21. ncbi request reprint Stabilization of lysozyme mass extracted from lotrafilcon silicone hydrogel contact lenses
    Lakshman N Subbaraman
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada
    Optom Vis Sci 82:209-14. 2005
    ..The purpose of this study was to devise a method whereby lysozyme mass would be preserved over time to allow for its accurate quantitation after its removal from SH lenses...
  22. ncbi request reprint Validity of pachymetric measurements by manipulating the acoustic factor of Orbscan II
    Fenghe Lu
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Canada
    Eye Contact Lens 32:78-83. 2006
    ..To assess the validity of pachymetric measurements by examining the constancy of the acoustic factor (AF) of the Orbscan II (Orbtek, Bausch & Lomb, Rochester, NY) after overnight rigid gas-permeable (RGP) contact lens wear...
  23. doi request reprint Impact of fluorescent probes on albumin sorption profiles to ophthalmic biomaterials
    Doerte Luensmann
    School of Optometry, Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario N2L3G1, Canada
    J Biomed Mater Res B Appl Biomater 94:327-36. 2010
    ..BSA profiles to pHEMA-based and silicone hydrogel lenses were highly dependent on the fluorescent probe used and none of the probes accurately reflected quantitative protein levels for the lens materials investigated...
  24. doi request reprint Thickness mapping of the cornea and epithelium using optical coherence tomography
    Sameena Haque
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 85:E963-76. 2008
    ....
  25. doi request reprint A solid-phase assay for the quantitation of total protein eluted from balafilcon, lotrafilcon, and etafilcon contact lenses
    Mary Ann Glasier
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Curr Eye Res 33:631-40. 2008
    ....
  26. ncbi request reprint Confocal microscopy and albumin penetration into contact lenses
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 84:839-47. 2007
    ..To develop a novel in vitro method to detect the depth of penetration of the tear film protein albumin into contact lens materials using confocal laser scanning microscopy (CLSM)...
  27. ncbi request reprint Kinetics of in vitro lysozyme deposition on silicone hydrogel, PMMA, and FDA groups I, II, and IV contact lens materials
    Lakshman N Subbaraman
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Curr Eye Res 31:787-96. 2006
    ....
  28. ncbi request reprint Protein deposition and clinical symptoms in daily wear of etafilcon lenses
    Lakshman N Subbaraman
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 89:1450-9. 2012
    ..To determine the relationship between clinical signs and symptoms and protein deposition over 8 h of wear of etafilcon A lenses in symptomatic and asymptomatic contact lens wearers...
  29. doi request reprint Quantification of non-polar lipid deposits on senofilcon a contact lenses
    Miriam Heynen
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 88:1172-9. 2011
    ....
  30. doi request reprint In vitro analysis of the physical properties of contact lens blister pack solutions
    Kara L Menzies
    University of Waterloo, Ontario, Canada
    Optom Vis Sci 88:493-501. 2011
    ..In addition, two saline solutions were tested for comparison purposes...
  31. ncbi request reprint Corneal refractive therapy with different lens materials, part 1: corneal, stromal, and epithelial thickness changes
    Sameena Haque
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 84:343-8. 2007
    ..Change in thickness of the total cornea, stroma, and epithelium was measured across the horizontal meridian using optical coherence tomography (OCT)...
  32. ncbi request reprint Clinical signs and symptoms in post-menopausal females with symptoms of dry eye
    Sruthi Srinivasan
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200, University Avenue West, Waterloo, ON N2L 3G1, Canada
    Ophthalmic Physiol Opt 28:365-72. 2008
    ..To characterize clinical signs and symptoms in a group of post-menopausal (PM) females who present with and without symptoms of dry eye...
  33. ncbi request reprint Protein deposition on a lathe-cut silicone hydrogel contact lens material
    Lakshman N Subbaraman
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 86:244-50. 2009
    ..To determine the quantity of total protein, total lysozyme, and the conformational state of lysozyme deposited on a novel, lathe-cut silicone hydrogel (SiHy) contact lens material (sifilcon A) after 3 months of wear...
  34. ncbi request reprint Precorneal and pre- and postlens tear film thickness measured indirectly with optical coherence tomography
    Jianhua Wang
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Invest Ophthalmol Vis Sci 44:2524-8. 2003
    ..To demonstrate the feasibility of indirectly measuring the precorneal tear film thickness and pre- and postlens tear film (PLTF) thickness using optical coherence tomography (OCT)...
  35. doi request reprint Impact of a rub and rinse on solution-induced corneal staining
    Rachael C Peterson
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Canada ON N2L 3G1
    Optom Vis Sci 87:1030-6. 2010
    ..To investigate whether the inclusion of a rub and rinse step before contact lens disinfection has an impact on solution-induced corneal staining...
  36. doi request reprint Infrared imaging of meibomian gland structure using a novel keratograph
    Sruthi Srinivasan
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 89:788-94. 2012
    ..To examine the ability of a novel non-contact device (Keratograph 4) to image the meibomian gland (MG) structures and their morphological changes in the upper and lower eyelids...
  37. pmc Contact lens physical properties and lipid deposition in a novel characterized artificial tear solution
    Holly Lorentz
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Mol Vis 17:3392-405. 2011
    ....
  38. ncbi request reprint The impact of contact angle on the biocompatibility of biomaterials
    Kara L Menzies
    FAAO School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 87:387-99. 2010
    ..This article reviews the impact of contact angle on the biocompatibility of tissue engineering substrates, blood-contacting devices, dental implants, intraocular lenses, and contact lens materials...
  39. ncbi request reprint The impact of lipid on contact angle wettability
    Holly Lorentz
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 84:946-53. 2007
    ..To analyze the effect of in vitro lipid doping on conventional hydrogel (CH) and silicone hydrogel (SH) lens wettability, assessed by sessile drop contact angle (CA) measurement...
  40. ncbi request reprint Topographical thickness of the epithelium and total cornea after overnight wear of reverse-geometry rigid contact lenses for myopia reduction
    Jianhua Wang
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Invest Ophthalmol Vis Sci 44:4742-6. 2003
    ..To investigate topographical thickness changes of the epithelium and total cornea measured with optical coherence tomography (OCT) after overnight wear of rigid gas-permeable lenses...
  41. doi request reprint Epithelial thickness changes from the induction of myopia with CRTH RGP contact lenses
    Sameena Haque
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada
    Invest Ophthalmol Vis Sci 49:3345-50. 2008
    ..To investigate changes in epithelial thickness after overnight wear of CRTH rigid gas-permeable (RGP) lenses (Paragon Vision Sciences, Mesa, AZ) for the correction of hyperopia...
  42. doi request reprint Impact of silicone hydrogel lenses and solutions on corneal epithelial permeability
    Stephanie Duench
    Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 90:546-56. 2013
    ..Secondarily, the aim was to see if there was any correlation between corneal staining and EBF...
  43. ncbi request reprint Physical entrapment of hyaluronic acid during synthesis results in extended release from model hydrogel and silicone hydrogel contact lens materials
    Andrea Weeks
    School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada
    Eye Contact Lens 39:179-85. 2013
    ....
  44. doi request reprint The impact of intermittent air exposure on lipid deposition
    Holly Lorentz
    Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 89:1574-81. 2012
    ..To analyze the impact of intermittent air exposure on the in vitro deposition of two radioactive lipids on various contact lens (CL) materials, using a custom-designed model blink cell...
  45. doi request reprint Using an in vitro model of lipid deposition to assess the efficiency of hydrogen peroxide solutions to remove lipid from various contact lens materials
    Holly Lorentz
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada
    Curr Eye Res 37:777-86. 2012
    ..To test the ability of two commercially available hydrogen peroxide disinfection solutions, one containing a surfactant and one without, to remove lipid from various contact lens materials using in vitro radiochemical experiments...
  46. ncbi request reprint Use of a photographic manipulation tool to assess corneal vascular response
    Jill Woods
    Centre for Contact Lens Research, University of Waterloo, Ontario, Canada
    Optom Vis Sci 89:215-20. 2012
    ..Corneal vasculature change in contact lens wearers has been linked to the level of hypoxia within the cornea.To assess the impact a treatment has on limbal vessels, a sensitive method of measurement and quantification is required...
  47. ncbi request reprint Comfort and vision with silicone hydrogel lenses: effect of compliance
    Kathryn Dumbleton
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 87:421-5. 2010
    ..The purpose of this analysis was to investigate the effect of compliance with MRRF on comfort and vision in SH wearers...
  48. doi request reprint In vitro contact angle analysis and physical properties of blister pack solutions of daily disposable contact lenses
    Kara L Menzies
    Centre for Contact Lens Research, University of Waterloo, Waterloo, ON, Canada
    Eye Contact Lens 36:10-8. 2010
    ..The purpose of this study was to measure the advancing and receding contact angles (CAs) of five daily disposable (DD) lenses and the osmolality, surface tension (ST), and pH of each blister pack solution...
  49. doi request reprint Uptake and release of ciprofloxacin-HCl from conventional and silicone hydrogel contact lens materials
    Alex Hui
    From the Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Eye Contact Lens 34:266-71. 2008
    ..To investigate the uptake and release characteristics of the antibiotic ciprofloxacin-HCl in conventional and silicone hydrogel lenses, and evaluate their potential as therapeutic drug delivery devices...
  50. ncbi request reprint Objective and subjective responses in patients refitted to daily-wear silicone hydrogel contact lenses
    Kathryn Dumbleton
    Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 83:758-68. 2006
    ..The purpose of this study was to investigate the clinical performance and physiological responses in a group of successful long-term wearers of conventional hydrogel lenses when refitted with DW SiH contact lenses...
  51. ncbi request reprint Imaging protein deposits on contact lens materials
    Jonathan H Teichroeb
    Department of Physics and Astronomy, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 85:1151-64. 2008
    ..The purpose of this study was to investigate the use of in situ imaging methods to examine protein deposition on conventional poly(2-hydroxyethyl methacrylate) (polyHEMA)-based and silicone hydrogel contact lens materials...
  52. doi request reprint Kinetics of lysozyme activity recovered from conventional and silicone hydrogel contact lens materials
    Lakshman N Subbaraman
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L3G1, Canada
    J Biomater Sci Polym Ed 21:343-58. 2010
    ..This variation in activity recovered from lenses could be due to the differences in surface/bulk material properties or the location of lysozyme on these lenses...
  53. ncbi request reprint Contact lenses for antifungal ocular drug delivery: a review
    Chau Minh Phan
    Centre for Contact Lens Research, School of Optometry and Vision Science, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada 1 519 888 4567 Extn 36547
    Expert Opin Drug Deliv 11:537-46. 2014
    ..A CL can serve as a drug reservoir to continuously release drugs to the cornea, while limiting drug loss through tears, blinking, drainage and non-specific absorption...
  54. ncbi request reprint Quantity and conformation of lysozyme deposited on conventional and silicone hydrogel contact lens materials using an in vitro model
    Maciej Suwala
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Eye Contact Lens 33:138-43. 2007
    ..To determine the activity of hen egg lysozyme (HEL) deposited on conventional and silicone hydrogel contact lens materials by using an in vitro model...
  55. doi request reprint Inhibition of defocus-induced myopia in chickens
    Jill Woods
    Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, Ontario, Canada
    Invest Ophthalmol Vis Sci 54:2662-8. 2013
    ..To determine the effect of wearing a lens with a unique peripheral optical design on the development and progression of defocus-induced myopia in newly hatched chickens...
  56. doi request reprint The impact of tear film components on in vitro lipid uptake
    Holly Lorentz
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, Canada
    Optom Vis Sci 89:856-67. 2012
    ..To analyze the influence of various tear film components on in vitro deposition of two lipids (cholesterol and phosphatidylcholine) on three contact lens materials...
  57. doi request reprint Impact of tear film components on lysozyme deposition to contact lenses
    Alan Ng
    Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 89:392-400. 2012
    ..To investigate the impact of lactoferrin and lipids on the kinetic deposition of lysozyme on silicone and conventional hydrogel lenses, using a complex artificial tear solution (ATS)...
  58. doi request reprint Impact of multipurpose solutions released from contact lenses on corneal cells
    Nicole C Tanti
    Department of Systems Design Engineering, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 88:483-92. 2011
    ..To assess, in vitro, the effect of the release of contact lens multipurpose solutions (MPS) from two silicone hydrogel lenses on human corneal epithelial cells...
  59. doi request reprint Immobilized hyaluronic acid containing model silicone hydrogels reduce protein adsorption
    Mark Van Beek
    Department of Chemical Engineering, McMaster University, 1280 Main St West, Hamilton, Ontario, Canada
    J Biomater Sci Polym Ed 19:1425-36. 2008
    ....
  60. doi request reprint Kinetics of in vitro lactoferrin deposition on silicone hydrogel and FDA group II and group IV hydrogel contact lens materials
    Lisa M Chow
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, Canada N2L 3G1
    J Biomater Sci Polym Ed 20:71-82. 2009
    ..The kinetics of lactoferrin deposition on contact lens materials depend on the chemical structure of the lens material...
  61. doi request reprint Tear lipocalin and lysozyme in Sjögren and non-Sjögren dry eye
    Barbary Caffery
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 85:661-7. 2008
    ..To evaluate the concentration of tear lipocalin, lysozyme, and total protein in Sjögren's Syndrome (SS), non-Sjögren's keratoconjunctivitis sicca (KCS), and non-dry-eyed (NDE) individuals...
  62. ncbi request reprint Efficacy of an extraction solvent used to quantify albumin deposition on hydrogel contact lens materials
    Lakshman N Subbaraman
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, ON, Canada
    Eye Contact Lens 35:76-80. 2009
    ..The purpose of this study was to determine the efficacy of TFA/ACN in extracting albumin from SH and a CH group IV lens material using an in vitro model...
  63. ncbi request reprint Lipid deposition on hydrogel contact lenses: how history can help us today
    Holly Lorentz
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 84:286-95. 2007
    ....
  64. ncbi request reprint In vitro uptake and release of natamycin from conventional and silicone hydrogel contact lens materials
    Chau Minh Phan
    Centre for Contact Lens Research, School of Optometry and Vision Science, Waterloo, Ontario, Canada
    Eye Contact Lens 39:162-8. 2013
    ....
  65. doi request reprint Delivery of ketotifen fumarate by commercial contact lens materials
    Anthony Soluri
    Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 89:1140-9. 2012
    ..To investigate the uptake and delivery of the anti-allergy drug ketotifen fumarate (KF) by commercially available contact lenses...
  66. doi request reprint Protein deposition on contact lenses: the past, the present, and the future
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada
    Cont Lens Anterior Eye 35:53-64. 2012
    ..Newer approaches incorporating phosphorylcholine, polyethers or hyaluronic acid into potential contact lens materials result in reduced protein deposition rates compared to current lens materials...
  67. ncbi request reprint Apparent time-dependent differences in inferior tear meniscus height in human subjects with mild dry eye symptoms
    Sruthi Srinivasan
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada
    Clin Exp Optom 90:345-50. 2007
    ..The aim of the study was to track the volume of tears contained in the inferior tear meniscus over the course of the day in subjects with symptoms of mild dry eye and a control asymptomatic group...
  68. ncbi request reprint Corneal and epithelial thickness changes after 4 weeks of overnight corneal refractive therapy lens wear, measured with optical coherence tomography
    Sameena Haque
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, N2L 3G1 Canada
    Eye Contact Lens 30:189-93; discussion 205-6. 2004
    ..To investigate thickness changes of the total cornea and epithelium across the horizontal corneal meridian after 4 weeks of overnight corneal refractive therapy (CRT) rigid contact lens (Paragon Vision Sciences, Mesa, AZ) wear...
  69. doi request reprint Physical properties of soft contact lens solutions
    Kristine Dalton
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 85:122-8. 2008
    ..To investigate the physical properties of commercially available soft contact lens solutions...
  70. doi request reprint Patient use of smartphones to communicate subjective data in clinical trials
    Craig A Woods
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 88:290-4. 2011
    ..This technical note reports on the utility of the BlackBerry smartphone to collect such data and why such a system provides advantages over other methods to report subjective ratings in clinical studies...
  71. doi request reprint Confocal microscopy and optical coherence tomography imaging of hereditary granular dystrophy
    Kristine Dalton
    School of Optometry, University of Waterloo, Ontario, Canada
    Cont Lens Anterior Eye 33:33-40. 2010
    ....
  72. pmc MUC16 expression in Sjogren's syndrome, KCS, and control subjects
    Barbara Caffery
    Center for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada
    Mol Vis 14:2547-55. 2008
    ..The relationship of tear flow and soluble MUC16 concentration was also measured...
  73. ncbi request reprint Corneal and epithelial thickness in keratoconus: a comparison of ultrasonic pachymetry, Orbscan II, and optical coherence tomography
    Sameena Haque
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada
    J Refract Surg 22:486-93. 2006
    ..To compare corneal thickness measurements in individuals with keratoconus using optical coherence tomography (OCT), Orbscan II, and ultrasonic pachymetry and to measure epithelial and stromal thickness in these individuals using OCT...
  74. doi request reprint Patient and practitioner compliance with silicone hydrogel and daily disposable lens replacement in the United States
    Kathy Dumbleton
    Centre for Contact Lens Research, University of Waterloo, Canada
    Eye Contact Lens 35:164-71. 2009
    ....
  75. doi request reprint Uptake and release of dexamethasone phosphate from silicone hydrogel and group I, II, and IV hydrogel contact lenses
    Adrienne Boone
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Eye Contact Lens 35:260-7. 2009
    ..To investigate the uptake and release kinetics of the synthetic glucocorticoid anti-inflammatory drug dexamethasone into various conventional and silicone hydrogel contact lens materials...
  76. doi request reprint Contact lens cases: the missing link in contact lens safety?
    Brad J Hall
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Eye Contact Lens 36:101-5. 2010
    ..To summarize a variety of issues associated with contact lens case contamination and discuss appropriate methods that can limit this...
  77. doi request reprint Albumin adsorption to contact lens materials: a review
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200, University Avenue West, Waterloo, Ontario, N2L 3G1, Canada
    Cont Lens Anterior Eye 31:179-87. 2008
    ..This review paper summarizes the impact of individual material compositions, water content, hydrophobicity and electrostatic attraction on the adsorption behavior of the protein albumin...
  78. doi request reprint Tear meniscus height determination using the OCT2 and the RTVue-100
    Adam Keech
    Centre for Contact Lens Research, and School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 86:1154-9. 2009
    ..To compare anterior segment spectral-domain optical coherence tomography (SOCT) tear meniscus height (TMH) measures with those from the more commonly used time-domain OCT (TOCT)...
  79. ncbi request reprint Atypical manifestation of upper lid margin staining in silicone hydrogel lens wearers with symptoms of dry eye
    Jalaiah Varikooty
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200, University Avenue West, Waterloo, Ontario N2L 3G1, Canada
    Cont Lens Anterior Eye 31:44-6. 2008
    ..To report an atypical manifestation of upper lid margin staining (ULMS) that occurred in adapted silicone hydrogel (SH) contact lens wearers who complained of ocular surface dryness...
  80. doi request reprint Outcomes of wavefront-guided laser in situ keratomileusis for hyperopia
    Nancy J Keir
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada
    J Cataract Refract Surg 37:886-93. 2011
    ..To determine the impact of wavefront-guided laser in situ keratomileusis (LASIK) for hyperopia on corrected distance visual acuity (CDVA), contrast sensitivity, and higher-order aberrations (HOAs)...
  81. doi request reprint Repeatability of pachymetry and thinnest point localization using a fourier-domain optical coherence tomographer
    Adam Keech
    Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 87:736-41. 2010
    ..The location of the thinnest point was also described using vector analysis, and repeatability of the localization of the thinnest point was calculated...
  82. ncbi request reprint The measurement of corneal epithelial thickness in response to hypoxia using optical coherence tomography
    Jianhua Wang
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Am J Ophthalmol 133:315-9. 2002
    ..To determine if corneal epithelial thickness increases in association with corneal edema induced by wearing soft contact lenses during eye closure...
  83. ncbi request reprint Relation between optical coherence tomography and optical pachymetry measurements of corneal swelling induced by hypoxia
    Jianhua Wang
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada
    Am J Ophthalmol 134:93-8. 2002
    ..To determine the relation between optical coherence tomography (OCT) and optical pachymetry (OP) measurements of corneal swelling induced by hypoxia...
  84. ncbi request reprint Hyaluronic acid containing hydrogels for the reduction of protein adsorption
    Mark Van Beek
    Department of Chemical Engineering, McMaster University, Hamilton, ON, Canada L8S 4L7
    Biomaterials 29:780-9. 2008
    ..The results provide insight into the mechanisms of comfort improvement with commercially available lens materials and suggest that HA containing materials may have significant potential for use in contact lens applications...
  85. ncbi request reprint Growth factors in the tear film: role in tissue maintenance, wound healing, and ocular pathology
    Bettina Klenkler
    Department of Chemical Engineering, McMaster University, Hamilton, ON, Canada
    Ocul Surf 5:228-39. 2007
    ..Animal models to test therapeutic approaches must be developed...
  86. ncbi request reprint Microbial keratitis and the role of rub and rinsing
    Victoria Butcko
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Eye Contact Lens 33:421-3; discussion 424-5. 2007
    ..This article reviews the literature on whether such a process should be recommended to contact lens wearers...
  87. doi request reprint Subjective and objective variation of the tear film pre- and post-sleep
    Etty Bitton
    Ecole d Optometrie, Universite de Montreal, Montreal, Quebec, Canada
    Optom Vis Sci 85:740-9. 2008
    ..This study investigates the POTF volume and stability, bulbar hyperemia (BH), tear ferning (TF) and the participant's subjective symptoms, pre- and post-sleep...
  88. ncbi request reprint Variability of the analysis of the tear meniscus height by optical coherence tomography
    Etty Bitton
    Ecole d Optometrie, Universite de Montreal, Montreal, Quebec, Canada
    Optom Vis Sci 84:903-8. 2007
    ..The purpose of this study was to evaluate the inter and intra observer variability in TMH assessment using OCT...