Sindhu R Johnson

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. doi request reprint Dual therapy in IPAH and SSc-PAH. A qualitative systematic review
    Sindhu R Johnson
    University Health Network, Pulmonary Hypertension Programme, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada
    Respir Med 106:730-9. 2012
  2. pmc Validation of potential classification criteria for systemic sclerosis
    Sindhu R Johnson
    Toronto Western Hospital, Mount Sinai Hospital, and University of Toronto, Toronto, Ontario, Canada
    Arthritis Care Res (Hoboken) 64:358-67. 2012
  3. doi request reprint Warfarin in systemic sclerosis-associated and idiopathic pulmonary arterial hypertension. A Bayesian approach to evaluating treatment for uncommon disease
    Sindhu R Johnson
    Division of Rheumatology, Department of Medicine, Toronto Western Hospital, Toronto, Ontario, Canada
    J Rheumatol 39:276-85. 2012
  4. ncbi request reprint Classification criteria for systemic sclerosis subsets
    Sindhu R Johnson
    Division of Rheumatology, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 34:1855-63. 2007
  5. doi request reprint Shifting our thinking about uncommon disease trials: the case of methotrexate in scleroderma
    Sindhu R Johnson
    Division of Rheumatology, Toronto Western Hospital, Ground Floor, East Wing, 399 Bathurst Street, Toronto, ON M5T 2S8
    J Rheumatol 36:323-9. 2009
  6. doi request reprint Methods to elicit beliefs for Bayesian priors: a systematic review
    Sindhu R Johnson
    Division of Rheumatology, Department of Medicine, University Health Network, Toronto, Ontario M5T 2S8, Canada
    J Clin Epidemiol 63:355-69. 2010
  7. doi request reprint A valid and reliable belief elicitation method for Bayesian priors
    Sindhu R Johnson
    Division of Rheumatology, Department of Medicine, Toronto Western Hospital, University Health Network, Toronto, Ontario M5T 2S8, Canada
    J Clin Epidemiol 63:370-83. 2010
  8. doi request reprint Effect of warfarin on survival in scleroderma-associated pulmonary arterial hypertension (SSc-PAH) and idiopathic PAH. Belief elicitation for Bayesian priors
    Sindhu R Johnson
    Division of Rheumatology, Toronto Western Hospital, Toronto, Ontario M5T 2S8, Canada
    J Rheumatol 38:462-9. 2011
  9. doi request reprint Pulmonary hypertension in systemic sclerosis and systemic lupus erythematosus
    S R Johnson
    Division of Rheumatology, Dept of Medicine, University Health Network, Mount Sinai Hospital and University of Toronto, ON, Canada
    Eur Respir Rev 20:277-86. 2011
  10. ncbi request reprint Is self-reported improvement in osteoarthritis pain and disability reflected in objective measures?
    Sindhu R Johnson
    Department of Health Policy, Management and Evaluation, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 34:159-64. 2007

Detail Information

Publications31

  1. doi request reprint Dual therapy in IPAH and SSc-PAH. A qualitative systematic review
    Sindhu R Johnson
    University Health Network, Pulmonary Hypertension Programme, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada
    Respir Med 106:730-9. 2012
    ..However, patients often deteriorate on monotherapy. The objective of this study is to evaluate the effect of dual therapy on outcomes in IPAH and SSc-PAH...
  2. pmc Validation of potential classification criteria for systemic sclerosis
    Sindhu R Johnson
    Toronto Western Hospital, Mount Sinai Hospital, and University of Toronto, Toronto, Ontario, Canada
    Arthritis Care Res (Hoboken) 64:358-67. 2012
    ..Potential items for classification were reduced to 23 using Delphi and nominal group techniques. We evaluated the face, discriminant, and construct validity of the items to be further studied as potential criteria...
  3. doi request reprint Warfarin in systemic sclerosis-associated and idiopathic pulmonary arterial hypertension. A Bayesian approach to evaluating treatment for uncommon disease
    Sindhu R Johnson
    Division of Rheumatology, Department of Medicine, Toronto Western Hospital, Toronto, Ontario, Canada
    J Rheumatol 39:276-85. 2012
    ..There is no evidence to support this in SSc-PAH and the evidence in IPAH is conflicting. We evaluated the ability of warfarin to improve survival using 2 large SSc-PAH and IPAH cohorts...
  4. ncbi request reprint Classification criteria for systemic sclerosis subsets
    Sindhu R Johnson
    Division of Rheumatology, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 34:1855-63. 2007
    ..To evaluate the measurement properties of criteria for systemic sclerosis (SSc) subsets for classification of patients in SSc trials, and to determine if any one criteria set confers measurement advantage over others...
  5. doi request reprint Shifting our thinking about uncommon disease trials: the case of methotrexate in scleroderma
    Sindhu R Johnson
    Division of Rheumatology, Toronto Western Hospital, Ground Floor, East Wing, 399 Bathurst Street, Toronto, ON M5T 2S8
    J Rheumatol 36:323-9. 2009
    ..05 as "negative." Our study demonstrates how Bayesian analysis conveys more relevant information to clinicians - using the example of methotrexate (MTX) in systemic sclerosis (SSc)...
  6. doi request reprint Methods to elicit beliefs for Bayesian priors: a systematic review
    Sindhu R Johnson
    Division of Rheumatology, Department of Medicine, University Health Network, Toronto, Ontario M5T 2S8, Canada
    J Clin Epidemiol 63:355-69. 2010
    ..We review belief-elicitation methods for Bayesian analysis and determine if any of them had an incremental value over the others based on its validity, reliability, and responsiveness...
  7. doi request reprint A valid and reliable belief elicitation method for Bayesian priors
    Sindhu R Johnson
    Division of Rheumatology, Department of Medicine, Toronto Western Hospital, University Health Network, Toronto, Ontario M5T 2S8, Canada
    J Clin Epidemiol 63:370-83. 2010
    ..The objectives of this study were to evaluate the feasibility, validity, and reliability of a belief elicitation method for Bayesian priors...
  8. doi request reprint Effect of warfarin on survival in scleroderma-associated pulmonary arterial hypertension (SSc-PAH) and idiopathic PAH. Belief elicitation for Bayesian priors
    Sindhu R Johnson
    Division of Rheumatology, Toronto Western Hospital, Toronto, Ontario M5T 2S8, Canada
    J Rheumatol 38:462-9. 2011
    ..A prerequisite for a trial is the demonstration of community uncertainty. We evaluated experts' beliefs about the effect of warfarin on 3-year survival in SSc-PAH and IPAH, and factors that influence warfarin use...
  9. doi request reprint Pulmonary hypertension in systemic sclerosis and systemic lupus erythematosus
    S R Johnson
    Division of Rheumatology, Dept of Medicine, University Health Network, Mount Sinai Hospital and University of Toronto, ON, Canada
    Eur Respir Rev 20:277-86. 2011
    ..In doing so, we will compare and contrast these two diseases, highlight clinically useful features, discuss methodological limitations of existing data, and draw attention to areas where research is needed...
  10. ncbi request reprint Is self-reported improvement in osteoarthritis pain and disability reflected in objective measures?
    Sindhu R Johnson
    Department of Health Policy, Management and Evaluation, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 34:159-64. 2007
    ..To determine if self-reported improvements in pain and function correlate with improvement in objective measures of disease in osteoarthritis (OA)...
  11. doi request reprint Ethnic influence on disease manifestations and autoantibodies in Chinese-descent patients with systemic sclerosis
    Andrea H L Low
    University of Toronto, Department of Medicine, Mount Sinai Hospital, Joseph and Wolf Lebovic Building, 60 Murray Street, Room 2 004, Box 9, Toronto, Ontario M5T 3L9, Canada
    J Rheumatol 36:787-93. 2009
    ..To investigate ethnic influence on disease manifestations and autoantibody profile in patients of Chinese descent with systemic sclerosis (SSc)...
  12. ncbi request reprint Multicriteria decision analysis methods with 1000Minds for developing systemic sclerosis classification criteria
    Sindhu R Johnson
    Division of Rheumatology, Department of Medicine, Toronto Western Hospital, University of Toronto, Ground Floor, East Wing, 399 Bathurst Street, Toronto, Ontario, Canada M5T 2S8 Division of Rheumatology, Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Electronic address
    J Clin Epidemiol 67:706-14. 2014
    ....
  13. ncbi request reprint Prognostic factors for survival in scleroderma associated pulmonary arterial hypertension
    Sindhu R Johnson
    University Health Network, University of Toronto, Toronto, ON, Canada
    J Rheumatol 35:1584-90. 2008
    ..Our objectives were (1) to identify factors associated with survival in SSc-PAH and (2) to evaluate the methodologic quality of prognostic studies against current standards...
  14. ncbi request reprint Quality of life and functional status in systemic sclerosis compared to other rheumatic diseases
    Sindhu R Johnson
    Division of Rheumatology, University Health Network, University of Toronto, Ontario, Canada
    J Rheumatol 33:1117-22. 2006
    ....
  15. doi request reprint ANCA-associated vasculitis in systemic sclerosis report of 3 cases
    Mohammed A Omair
    Division of Rheumatology, Department of Medicine, Mount Sinai Hospital, University Health Network, University of Toronto, Toronto, ON, Canada
    Rheumatol Int 33:139-43. 2013
    ..Positive anti-Scl-70 antibody is found commonly in these patients. Different treatment modalities are effective. Serious infections can complicate therapy and lead to death...
  16. ncbi request reprint Thrombotic arteriopathy and anticoagulation in pulmonary hypertension
    Sindhu R Johnson
    Division of Rheumatology, University Health Network, University of Toronto, Canada
    Chest 130:545-52. 2006
    ..To date, the data from observational studies suggest that anticoagulation with warfarin is an effective intervention in patients with IPAH. Its efficacy in other causes of PAH remains speculative...
  17. ncbi request reprint Classification criteria in rheumatic diseases: a review of methodologic properties
    Sindhu R Johnson
    University Health Network, Toronto, Ontario, Canada
    Arthritis Rheum 57:1119-33. 2007
    ..To identify classification criteria for the rheumatic diseases and to evaluate their measurement properties and methodologic rigor using current measurement standards...
  18. ncbi request reprint Ethnic variation in disease patterns and health outcomes in systemic lupus erythematosus
    Sindhu R Johnson
    Division of Rheumatology, Centre for Prognostic Studies in the Rheumatic Diseases, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 33:1990-5. 2006
    ..In a single-center multiethnic lupus cohort, to investigate the influence of ethnicity on the prevalence of cumulative renal and central nervous system (CNS) lupus disease and damage, overall end-organ damage, and mortality...
  19. ncbi request reprint Pulmonary veno-occlusive disease and scleroderma associated pulmonary hypertension
    Sindhu R Johnson
    Division of Rheumatology, Department of Pathology, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 33:2347-50. 2006
    ..In our case series, treatment with an endothelin receptor antagonist did not confer a beneficial treatment effect...
  20. doi request reprint Magnetic resonance imaging of the hand in systemic sclerosis
    Andrea H L Low
    Department of Medicine, Division of Rheumatology, Division of Musculoskeletal Imaging, University of Toronto, Mount Sinai Hospital, Toronto, Ontario, Canada
    J Rheumatol 36:961-4. 2009
    ..To evaluate the utility of magnetic resonance imaging (MRI) in systemic sclerosis (SSc)-associated arthropathy...
  21. ncbi request reprint The health assessment questionnaire disability index and scleroderma health assessment questionnaire in scleroderma trials: an evaluation of their measurement properties
    Sindhu R Johnson
    University of Toronto, Toronto, Ontario, Canada
    Arthritis Rheum 53:256-62. 2005
    ....
  22. ncbi request reprint Development, sensibility, and reliability of the Toronto Axial Spondyloarthritis Questionnaire in inflammatory bowel disease
    Khalid A Alnaqbi
    From the Department of Medicine, Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto Al Ain Hospital, Medical Institute, Al Ain, United Arab Emirates and Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 40:1726-35. 2013
    ..Our objectives were to develop a sensible and reliable questionnaire to identify undetected axSpA among patients with IBD...
  23. ncbi request reprint Low bone density in systemic sclerosis. A systematic review
    Mohammed A Omair
    From the Toronto Scleroderma Program, Division of Rheumatology, Department of Medicine, Mount Sinai Hospital Osteoporosis Program, Toronto General Hospital Division of Rheumatology, Department of Medicine, Toronto Western Hospital and Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 40:1881-90. 2013
    ....
  24. doi request reprint Survival after lung transplantation in systemic sclerosis. A systematic review
    Irfan Y Khan
    Pulmonary Hypertension Programme, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Respir Med 107:2081-7. 2013
    ..We secondarily evaluated SSc lung transplant recipient characteristics (age, sex, and type of SSc lung disease), and discussed post-lung transplantation survival of SSc patients and non-SSc patients (idiopathic PAH, and ILD)...
  25. ncbi request reprint Long-term safety and effectiveness of tumour necrosis factor inhibitors in systemic sclerosis patients with inflammatory arthritis
    Mohammed A Omair
    Mount Sinai Hospital, Toronto, Ontario, Canada
    Clin Exp Rheumatol 30:S55-9. 2012
    ..To assess the long-term safety and effectiveness of tumour necrosis factor (TNF) inhibitors in the treatment of systemic sclerosis (SSc) patients with inflammatory arthritis...
  26. ncbi request reprint Scleroderma: health services utilization from patients' perspective
    Sindhu R Johnson
    Division of Rheumatology, University Health Network, University of Toronto, Ontario, Canada
    J Rheumatol 33:1123-7. 2006
    ....
  27. doi request reprint Biologic therapy for systemic sclerosis: a systematic review
    Veerapong Phumethum
    Division of Rheumatology, Ground Floor, East Wing, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada
    J Rheumatol 38:289-96. 2011
    ..We review the evidence for the use of biologic agents to improve inflammatory arthritis, disability, and skin score, and we review adverse effects with biologic agents in patients with SSc...
  28. ncbi request reprint A review of the sapporo and revised Sapporo criteria for the classification of antiphospholipid syndrome. Where do the revised sapporo criteria add value?
    Raja S Bobba
    Division of Rheumatology, McMaster University, Hamilton, Ontario, Canada
    J Rheumatol 34:1522-7. 2007
    ....
  29. ncbi request reprint Classification in systemic sclerosis
    Sindhu R Johnson
    J Rheumatol 33:840-1. 2006
  30. ncbi request reprint Office capillaroscopy in systemic sclerosis
    Murray Baron
    McGill University, and Jewish General Hospital, Montreal, Quebec, Canada
    Clin Rheumatol 26:1268-74. 2007
    ..The ophthalmoscope is valid when compared to the microscope for detecting giant or dilated capillaries. We conclude that these techniques are useful office tools to detect capillary abnormalities in SSc...
  31. ncbi request reprint Erectile dysfunction and scleroderma
    Sindhu R Johnson
    J Rheumatol 31:2091; author reply 2091-2. 2004