A R Joffe

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. ncbi request reprint Brain death: understanding of the conceptual basis by pediatric intensivists in Canada
    Ari R Joffe
    Division of Pediatric Intensive Care, Department of Pediatrics, University of Alberta, Edmonton, Canada
    Arch Pediatr Adolesc Med 160:747-52. 2006
  2. pmc Plasma matrix metalloproteinases in neonates having surgery for congenital heart disease
    Ari R Joffe
    Department of Pediatrics
    Heart Int 4:e4. 2009
  3. pmc The ethics of donation and transplantation: are definitions of death being distorted for organ transplantation?
    Ari R Joffe
    Philos Ethics Humanit Med 2:28. 2007
  4. doi request reprint Are recent defences of the brain death concept adequate?
    Ari Joffe
    Stollery Children s Hospital, University of Alberta, Edmonton, Alberta, Canada
    Bioethics 24:47-53. 2010
  5. doi request reprint Donation after cardiac death: a survey of university student opinions on death and donation
    Ari R Joffe
    Department of Pediatrics, 3A3 Stollery Children s Hospital, University of Alberta, 8440 112 Street, Edmonton, AB, T6G 2B7, Canada
    Intensive Care Med 35:240-7. 2009
  6. doi request reprint Brain death and the cervical spinal cord: a confounding factor for the clinical examination
    A R Joffe
    Department of Pediatrics, 3A3 07 Stollery Children s Hospital, 8440 112 Street, University of Alberta, Edmonton, Alberta, Canada T6G 2B7
    Spinal Cord 48:2-9. 2010
  7. ncbi request reprint The neurological determination of death: what does it really mean?
    Ari Robin Joffe
    Department of Pediatrics, Division of Pediatric Critical Care, University of Alberta, Edmonton, Canada
    Issues Law Med 23:119-40. 2007
  8. ncbi request reprint A survey to determine the understanding of the conceptual basis and diagnostic tests used for brain death by neurosurgeons in Canada
    Ari R Joffe
    Department of Pediatrics, Division of Pediatric Intensive Care, University of Alberta, Edmonton, Canada
    Neurosurgery 61:1039-45; discussion 1046-7. 2007
  9. ncbi request reprint Some questions about brain death: a case report
    Ari R Joffe
    Department of Pediatrics, University of Alberta and Stollery Children s Hospital, Edmonton, Alberta, Canada
    Pediatr Neurol 37:289-91. 2007
  10. ncbi request reprint A 10-month-old infant with reversible findings of brain death
    Ari R Joffe
    Department of Pediatrics, University of Alberta and Stollery Children s Hospital, Edmonton, Alberta, Canada
    Pediatr Neurol 41:378-82. 2009

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Brain death: understanding of the conceptual basis by pediatric intensivists in Canada
    Ari R Joffe
    Division of Pediatric Intensive Care, Department of Pediatrics, University of Alberta, Edmonton, Canada
    Arch Pediatr Adolesc Med 160:747-52. 2006
    ..To determine whether pediatric intensivists in Canada are aware of the controversies regarding the concept of brain death (BD)...
  2. pmc Plasma matrix metalloproteinases in neonates having surgery for congenital heart disease
    Ari R Joffe
    Department of Pediatrics
    Heart Int 4:e4. 2009
    ..In neonates, further study should determine whether circulating matrix-metalloproteinases are useful biomarkers of disease activity locally within the myocardium, and hence of clinical outcomes...
  3. pmc The ethics of donation and transplantation: are definitions of death being distorted for organ transplantation?
    Ari R Joffe
    Philos Ethics Humanit Med 2:28. 2007
    ..I suggest that brain dead and DCD donors are not dead; whether organs can be harvested before death from these patients whose prognosis is death should be debated urgently...
  4. doi request reprint Are recent defences of the brain death concept adequate?
    Ari Joffe
    Stollery Children s Hospital, University of Alberta, Edmonton, Alberta, Canada
    Bioethics 24:47-53. 2010
    ..If brain death is death, a conceptual rationale for brain death being equivalent to death should be clarified, and this should be done urgently...
  5. doi request reprint Donation after cardiac death: a survey of university student opinions on death and donation
    Ari R Joffe
    Department of Pediatrics, 3A3 Stollery Children s Hospital, University of Alberta, 8440 112 Street, Edmonton, AB, T6G 2B7, Canada
    Intensive Care Med 35:240-7. 2009
    ..To determine if university students consider the donation after cardiac death donor as dead...
  6. doi request reprint Brain death and the cervical spinal cord: a confounding factor for the clinical examination
    A R Joffe
    Department of Pediatrics, 3A3 07 Stollery Children s Hospital, 8440 112 Street, University of Alberta, Edmonton, Alberta, Canada T6G 2B7
    Spinal Cord 48:2-9. 2010
    ..This study is a systematic review...
  7. ncbi request reprint The neurological determination of death: what does it really mean?
    Ari Robin Joffe
    Department of Pediatrics, Division of Pediatric Critical Care, University of Alberta, Edmonton, Canada
    Issues Law Med 23:119-40. 2007
    ..Whether this state of "neurological determination of death" is enough to justify the morality of harvesting organs prior to death is the real question. A potential solution to this question is discussed...
  8. ncbi request reprint A survey to determine the understanding of the conceptual basis and diagnostic tests used for brain death by neurosurgeons in Canada
    Ari R Joffe
    Department of Pediatrics, Division of Pediatric Intensive Care, University of Alberta, Edmonton, Canada
    Neurosurgery 61:1039-45; discussion 1046-7. 2007
    ..To determine the understanding of the conceptual basis and diagnostic tests used for brain death (BD) by neurosurgeons in Canada...
  9. ncbi request reprint Some questions about brain death: a case report
    Ari R Joffe
    Department of Pediatrics, University of Alberta and Stollery Children s Hospital, Edmonton, Alberta, Canada
    Pediatr Neurol 37:289-91. 2007
    ....
  10. ncbi request reprint A 10-month-old infant with reversible findings of brain death
    Ari R Joffe
    Department of Pediatrics, University of Alberta and Stollery Children s Hospital, Edmonton, Alberta, Canada
    Pediatr Neurol 41:378-82. 2009
    ..Together with previous reports, the present case calls into question the assumption that brain death as currently diagnosed is irreversible, and therefore equivalent to death of the patient...
  11. ncbi request reprint Lumbar puncture and brain herniation in acute bacterial meningitis: a review
    Ari R Joffe
    Department of Pediatrics, Divisions of Infectious Diseases and Critical Care, University of Alberta, Edmonton, Canada
    J Intensive Care Med 22:194-207. 2007
    ....
  12. ncbi request reprint Mortality after neonatal cardiac surgery: Prediction from mean arterial pressure after rewarming in the operating room
    Ari R Joffe
    Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    J Thorac Cardiovasc Surg 134:311-8. 2007
    ..To examine the predictive contribution of mean arterial pressure after rewarming to > or =34 degrees C in the operating room to mortality after cardiac surgery in infants < or =6 weeks old...
  13. ncbi request reprint Injury admissions to pediatric intensive care are predictable and preventable: a call to action
    Ari R Joffe
    Department of Pediatrics, Division of Pediatric Critical Care, Stollery Children s Hospital, University of Alberta, Edmonton, Alberta, Canada
    J Intensive Care Med 21:227-34. 2006
    ..Novel strategies to improve the public's perception of the cost of childhood injury are needed...
  14. ncbi request reprint Brain death is not death: a critique of the concept, criterion, and tests of brain death
    Ari R Joffe
    University of Alberta, and Stollery Children s Hospital, Edmonton, AB, Canada
    Rev Neurosci 20:187-98. 2009
    ..I conclude that brain death, while a devastating neurological state with a dismal prognosis, is not death...
  15. ncbi request reprint Specificity of radionuclide brain blood flow testing in brain death: case report and review
    Ari R Joffe
    Stollery Children s Hospital, University of Alberta, Edmonton, Alberta, Canada
    J Intensive Care Med 25:53-64. 2010
    ..Larger numbers of patients both with and without BD (but with severe brain injury) must be studied to determine the sensitivity and specificity of these tests..
  16. doi request reprint Survey of pediatricians' opinions on donation after cardiac death: are the donors dead?
    Ari R Joffe
    Department of Pediatrics, University of Alberta and Stollery Children s Hospital, Edmonton, Alberta, Canada
    Pediatrics 122:e967-74. 2008
    ..We set out to determine whether pediatricians consider the donation-after-cardiac-death donor as dead...
  17. ncbi request reprint The safety and efficacy of sustained inflations as a lung recruitment maneuver in pediatric intensive care unit patients
    Jonathan P Duff
    Division of Critical Care Medicine, Stollery Children s Hospital, University of Alberta, 8440 112 Street, 3A3 19 WMC, T6G 2B7, Edmonton, Alberta, Canada
    Intensive Care Med 33:1778-86. 2007
    ..To assess the safety and efficacy of sustained inflations (SI) as lung recruitment maneuvers (RMs) in ventilated pediatric intensive care unit (PICU) patients...
  18. ncbi request reprint Outcomes from an interprovincial program of newborn open heart surgery
    Charlene M T Robertson
    Departments of Pediatrics and Surgery, University of Alberta, Edmonton, Alberta, Canada
    J Pediatr 144:86-92. 2004
    ..Cumulative risk for adverse outcome was determined through univariate and multivariate analyses...
  19. doi request reprint Two-year survival, mental, and motor outcomes after cardiac extracorporeal life support at less than five years of age
    Laurance Lequier
    Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    J Thorac Cardiovasc Surg 136:976-983.e3. 2008
    ..Comprehensive outcome assessment of children receiving cardiac extracorporeal life support...
  20. ncbi request reprint Postoperative lactate concentrations predict the outcome of infants aged 6 weeks or less after intracardiac surgery: a cohort follow-up to 18 months
    Po Yin Cheung
    Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    J Thorac Cardiovasc Surg 130:837-43. 2005
    ..An observational cohort study was conducted in infants less than 6 weeks of age undergoing intracardiac surgery to examine the predictive value of serial postoperative lactate determination on survival and early childhood neurodevelopment...
  21. ncbi request reprint Two-year general and neurodevelopmental outcome after neonatal complex cardiac surgery in patients with deletion 22q11.2: a comparative study
    Joseph Atallah
    Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    J Thorac Cardiovasc Surg 134:772-9. 2007
    ..Neonatal complex cardiac surgery carries a significant risk for adverse neurodevelopmental outcome. We hypothesized this risk to be higher in patients with deletion 22q11.2...
  22. ncbi request reprint Early childhood health, growth, and neurodevelopmental outcomes after complete repair of total anomalous pulmonary venous connection at 6 weeks or younger
    Gwen Y Alton
    Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    J Thorac Cardiovasc Surg 133:905-11. 2007
    ....
  23. ncbi request reprint Prospective study of potassium-associated acute transfusion events in pediatric intensive care
    Christopher S Parshuram
    Department of Pediatrics, University of Alberta Hospital, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Crit Care Med 4:65-8. 2003
    ..This study sought to determine the biochemical and associated clinical effects of packed red blood cells transfusion in critically ill children...
  24. doi request reprint Association of hemoglobin and transfusion with outcome after operations for hypoplastic left heart
    Jaime Blackwood
    Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    Ann Thorac Surg 89:1378-84.e1-2. 2010
    ..Some studies suggest transfusion might contribute to adverse outcomes. This study investigated the association between hemoglobin concentration and transfusion with outcome in cyanotic neonates undergoing Norwood operations...
  25. doi request reprint The approach to delayed resuscitation in paediatric cardiac arrest: A survey of paediatric intensivists in Canada
    Ari R Joffe
    Department of Paediatrics, Division of Paediatric Intensive Care, University of Alberta, 8440 112 Street, Edmonton, Alberta, Canada T6G 2B7
    Resuscitation 80:318-23. 2009
    ..To determine how long a period of having had no cardiopulmonary-resuscitation (CPR) (delay time) is considered to result in subsequent futile efforts at resuscitation...
  26. doi request reprint Two-year survival and mental and psychomotor outcomes after the Norwood procedure: an analysis of the modified Blalock-Taussig shunt and right ventricle-to-pulmonary artery shunt surgical eras
    Joseph Atallah
    Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    Circulation 118:1410-8. 2008
    ..In our institution, surgical practice changed from use of the MBTS to use of the RVPA shunt in 2002. We analyzed survival and mental and psychomotor outcomes of the 2 consecutive surgical eras...
  27. doi request reprint The safety of targeted antibiotic therapy for ventilator-associated pneumonia: a multicenter observational study
    Ari R Joffe
    Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada T6G 2B7
    J Crit Care 23:82-90. 2008
    ..The aim of this study was to determine the safety of targeted antibiotic therapy (TT) in ventilator-associated pneumonia (VAP)...
  28. doi request reprint Comparison of two red-cell transfusion strategies after pediatric cardiac surgery: a subgroup analysis
    Ariane Willems
    Pediatric Intensive Care Unit, Department of Pediatrics, Universite de Montreal, Montreal, QC, Canada
    Crit Care Med 38:649-56. 2010
    ..a liberal transfusion strategy on new or progressive multiple organ dysfunction syndrome in children post cardiac surgery. The optimal transfusion threshold after cardiac surgery in children is unknown...
  29. doi request reprint Two-year neurodevelopmental outcomes of infants undergoing neonatal cardiac surgery for interrupted aortic arch: a descriptive analysis
    Chloe A Joynt
    Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    J Thorac Cardiovasc Surg 138:924-32. 2009
    ..This study determined neurodevelopmental outcomes of survivors of neonatal cardiac surgery for interrupted aortic arch through an interprovincial program and explored preoperative, intraoperative, and postoperative outcome predictors...
  30. ncbi request reprint Intermediate-term outcomes of the arterial switch operation for transposition of great arteries in neonates: alive but well?
    Darren H Freed
    Department of Surgery, University of Alberta, Edmonton, Alberta, Canada
    J Thorac Cardiovasc Surg 132:845-52. 2006
    ..Predictors of outcome are explored...