Alexandra L Jenkins

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Reduction of postprandial glycemia by the novel viscous polysaccharide PGX, in a dose-dependent manner, independent of food form
    Alexandra L Jenkins
    Rd, Glycemic Index Laboratories, Inc, 20 Victoria Street, 3rd Floor, Toronto, ON M5C 2N8 Canada
    J Am Coll Nutr 29:92-8. 2010
  2. pmc Effect of adding the novel fiber, PGX®, to commonly consumed foods on glycemic response, glycemic index and GRIP: a simple and effective strategy for reducing post prandial blood glucose levels--a randomized, controlled trial
    Alexandra L Jenkins
    Glycemic Index Laboratories, Inc, Toronto, ON, Canada
    Nutr J 9:58. 2010
  3. pmc 'Catalytic' doses of fructose may benefit glycaemic control without harming cardiometabolic risk factors: a small meta-analysis of randomised controlled feeding trials
    John L Sievenpiper
    Department of Pathology and Molecular Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada
    Br J Nutr 108:418-23. 2012
  4. pmc Effect of fructose on glycemic control in diabetes: a systematic review and meta-analysis of controlled feeding trials
    Adrian I Cozma
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, Toronto, Ontario, Canada
    Diabetes Care 35:1611-20. 2012
  5. doi request reprint Korean red ginseng (Panax ginseng C.A. Meyer) root fractions: differential effects on postprandial glycemia in healthy individuals
    Leanne R De Souza
    Clinical Nutrition and Risk Factor Modification Center and Li Ka Shing Knowledge Institute, St Michael s Hospital, 70 Richmond St E, Toronto, Ontario, Canada, M5C1N8
    J Ethnopharmacol 137:245-50. 2011
  6. pmc The effects of fructose intake on serum uric acid vary among controlled dietary trials
    D David Wang
    Clinical Nutrition and Risk Factor Modification Centre, St Michael s Hospital, Toronto, ON, Canada
    J Nutr 142:916-23. 2012
  7. doi request reprint Viscosity rather than quantity of dietary fibre predicts cholesterol-lowering effect in healthy individuals
    Vladimir Vuksan
    Li Ka Shing Knowledge Institute, Clinical Nutrition and Risk Factor Modification Centre, Saint Michael s, Toronto, ON, Canada
    Br J Nutr 106:1349-52. 2011
  8. ncbi request reprint Supplementation of conventional therapy with the novel grain Salba (Salvia hispanica L.) improves major and emerging cardiovascular risk factors in type 2 diabetes: results of a randomized controlled trial
    Vladimir Vuksan
    Risk Factor Modification Centre, St Michael s Hospital, 70 Richmond St East, Toronto, Ontario, Canada, M5C 1N8
    Diabetes Care 30:2804-10. 2007
  9. doi request reprint Effect of fructose on postprandial triglycerides: a systematic review and meta-analysis of controlled feeding trials
    D David Wang
    Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre, Toronto, ON, Canada
    Atherosclerosis 232:125-33. 2014
  10. pmc Comparable postprandial glucose reductions with viscous fiber blend enriched biscuits in healthy subjects and patients with diabetes mellitus: acute randomized controlled clinical trial
    Alexandra L Jenkins
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital and Li Ka Shing Knowledge Institute, 70 Richmond St E, Toronto, Ontario, Canada
    Croat Med J 49:772-82. 2008

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Reduction of postprandial glycemia by the novel viscous polysaccharide PGX, in a dose-dependent manner, independent of food form
    Alexandra L Jenkins
    Rd, Glycemic Index Laboratories, Inc, 20 Victoria Street, 3rd Floor, Toronto, ON M5C 2N8 Canada
    J Am Coll Nutr 29:92-8. 2010
    ..The objective of the study therefore was to determine palatability and effectiveness of escalating doses of PGX, a novel viscous polysaccharide (NVP), in reducing postprandial glycemia when added to a liquid and a solid meal...
  2. pmc Effect of adding the novel fiber, PGX®, to commonly consumed foods on glycemic response, glycemic index and GRIP: a simple and effective strategy for reducing post prandial blood glucose levels--a randomized, controlled trial
    Alexandra L Jenkins
    Glycemic Index Laboratories, Inc, Toronto, ON, Canada
    Nutr J 9:58. 2010
    ..This study explores whether these reductions are sustained when NVP is added to a range of commonly consumed foods or incorporated into a breakfast cereal...
  3. pmc 'Catalytic' doses of fructose may benefit glycaemic control without harming cardiometabolic risk factors: a small meta-analysis of randomised controlled feeding trials
    John L Sievenpiper
    Department of Pathology and Molecular Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada
    Br J Nutr 108:418-23. 2012
    ..There is a need for larger, longer ( ≥ 6 months) trials using 'catalytic' fructose to confirm these results...
  4. pmc Effect of fructose on glycemic control in diabetes: a systematic review and meta-analysis of controlled feeding trials
    Adrian I Cozma
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, Toronto, Ontario, Canada
    Diabetes Care 35:1611-20. 2012
    ..The effect of fructose on cardiometabolic risk in humans is controversial. We conducted a systematic review and meta-analysis of controlled feeding trials to clarify the effect of fructose on glycemic control in individuals with diabetes...
  5. doi request reprint Korean red ginseng (Panax ginseng C.A. Meyer) root fractions: differential effects on postprandial glycemia in healthy individuals
    Leanne R De Souza
    Clinical Nutrition and Risk Factor Modification Center and Li Ka Shing Knowledge Institute, St Michael s Hospital, 70 Richmond St E, Toronto, Ontario, Canada, M5C1N8
    J Ethnopharmacol 137:245-50. 2011
    ..Whether this effect is reproducible with a different KRG source is unclear. We therefore tested two root fractions from a KRG source with elevated ginsenoside levels to assess its effect on PPG...
  6. pmc The effects of fructose intake on serum uric acid vary among controlled dietary trials
    D David Wang
    Clinical Nutrition and Risk Factor Modification Centre, St Michael s Hospital, Toronto, ON, Canada
    J Nutr 142:916-23. 2012
    ..Hypercaloric fructose intake may, however, increase uric acid concentrations. The effect of the interaction of energy and fructose remains unclear. Larger, well-designed trials of fructose feeding at "real world" doses are needed...
  7. doi request reprint Viscosity rather than quantity of dietary fibre predicts cholesterol-lowering effect in healthy individuals
    Vladimir Vuksan
    Li Ka Shing Knowledge Institute, Clinical Nutrition and Risk Factor Modification Centre, Saint Michael s, Toronto, ON, Canada
    Br J Nutr 106:1349-52. 2011
    ..These data support the inclusion of high-viscosity fibre in the diet to reduce plasma lipids among apparently healthy individuals consuming a typical NA diet...
  8. ncbi request reprint Supplementation of conventional therapy with the novel grain Salba (Salvia hispanica L.) improves major and emerging cardiovascular risk factors in type 2 diabetes: results of a randomized controlled trial
    Vladimir Vuksan
    Risk Factor Modification Centre, St Michael s Hospital, 70 Richmond St East, Toronto, Ontario, Canada, M5C 1N8
    Diabetes Care 30:2804-10. 2007
    ..a novel whole grain that is rich in fiber, alpha-linolenic acid (ALA), and minerals to conventional treatment is associated with improvement in major and emerging cardiovascular risk factors in individuals with type 2 diabetes...
  9. doi request reprint Effect of fructose on postprandial triglycerides: a systematic review and meta-analysis of controlled feeding trials
    D David Wang
    Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre, Toronto, ON, Canada
    Atherosclerosis 232:125-33. 2014
    ..In the absence of consistent clinical evidence, concerns have been raised that fructose raises postprandial triglycerides...
  10. pmc Comparable postprandial glucose reductions with viscous fiber blend enriched biscuits in healthy subjects and patients with diabetes mellitus: acute randomized controlled clinical trial
    Alexandra L Jenkins
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital and Li Ka Shing Knowledge Institute, 70 Richmond St E, Toronto, Ontario, Canada
    Croat Med J 49:772-82. 2008
    ..To compare the blood glucose-lowering effect of a highly viscous fiber blend (VFB) added to a starchy snack on postprandial glycemia between healthy participants and participants with diabetes mellitus...
  11. doi request reprint Day-to-day variation in glycemic response elicited by white bread is not related to variation in satiety in humans
    Thomas M S Wolever
    Glycemic Index Laboratories, Inc, Toronto, Ontario, Canada
    Appetite 52:654-8. 2009
    ..4480+/-683 mm min, ns). The results were similar for males and females. These results do not support the hypothesis that glycemic responses per se influence feelings of satiety over the 2h period after eating...
  12. ncbi request reprint Five batches representative of Ontario-grown American ginseng root produce comparable reductions of postprandial glycemia in healthy individuals
    Anamaria Dascalu
    Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON M5S3E2, Canada
    Can J Physiol Pharmacol 85:856-64. 2007
    ..05.) American ginseng decreased postprandial glycemia and insulinemia; however, 40% of the batches did not reduce glycemia with the anticipated magnitude, irrespective of their saponin composition...
  13. ncbi request reprint Using cereal to increase dietary fiber intake to the recommended level and the effect of fiber on bowel function in healthy persons consuming North American diets
    Vladimir Vuksan
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, Toronto, Canada
    Am J Clin Nutr 88:1256-62. 2008
    ..Dietary fiber intake remains low despite increasing evidence for its health benefits, including laxation...
  14. ncbi request reprint Fiber facts: benefits and recommendations for individuals with type 2 diabetes
    Vladimir Vuksan
    Clinical Nutrition and Risk Factor Modification Centre, St Michael s Hospital, 70 Richmond Street East, Suite 100, Toronto, ON, M5C 1N8, Canada
    Curr Diab Rep 9:405-11. 2009
    ..Increasing consumption of foods containing fiber or use of fiber supplements could play an important role in managing diabetes with positive outcomes on vascular complications and reduced cardio-vascular disease risk...
  15. ncbi request reprint Modulation of Endothelial Function by Korean Red Ginseng (Panax ginseng C.A. Meyer) and its Components in Healthy Individuals: A Randomized Controlled Trial
    Elena Jovanovski
    Clinical Nutrition and Risk Factor Modification Centre, St Michael s Hospital, Toronto, ON, Canada Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada
    Cardiovasc Ther 32:163-9. 2014
    ....
  16. ncbi request reprint Glycemic index: overview of implications in health and disease
    David J A Jenkins
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital and Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Ontario, Canada
    Am J Clin Nutr 76:266S-73S. 2002
    ..Despite inconsistencies in the data, sufficient, positive findings have emerged to suggest that the dietary glycemic index is of potential importance in the treatment and prevention of chronic diseases...
  17. ncbi request reprint Korean red ginseng (Panax ginseng) improves glucose and insulin regulation in well-controlled, type 2 diabetes: results of a randomized, double-blind, placebo-controlled study of efficacy and safety
    Vladimir Vuksan
    Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Canada
    Nutr Metab Cardiovasc Dis 18:46-56. 2008
    ....
  18. ncbi request reprint Insulin resistance: concepts, controversies, and the role of nutrition
    John L Sievenpiper
    Clinical Nutrition and Risk Factor Modification Centre, St Michael s Hospital, Toronto, ON
    Can J Diet Pract Res 63:20-32. 2002
    ..Additional research is required to confirm the sustainability of this approach and sort out the determinants of insulin resistance so that more effective nutritional interventions will result...
  19. doi request reprint Effect of fructose on blood pressure: a systematic review and meta-analysis of controlled feeding trials
    Vanessa Ha
    Clinical Nutrition and Risk Factor Modification Centre, St Michael s Hospital, Toronto, Ontario, Canada
    Hypertension 59:787-95. 2012
    ..To confirm these results, longer and larger trials are needed. Contrary to previous concerns, we found that isocaloric substitution of fructose for other carbohydrates did not adversely affect blood pressure in humans...
  20. ncbi request reprint The Garden of Eden--plant based diets, the genetic drive to conserve cholesterol and its implications for heart disease in the 21st century
    David J A Jenkins
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, 61 Queen Street East, Ont, M5C 2T2, Toronto, Canada
    Comp Biochem Physiol A Mol Integr Physiol 136:141-51. 2003
    ....
  21. ncbi request reprint Type 2 diabetes and the vegetarian diet
    David J A Jenkins
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, Toronto, Ontario, Canada
    Am J Clin Nutr 78:610S-616S. 2003
    ..It is anticipated that their combined use in vegetarian diets will produce very significant metabolic advantages for the prevention and treatment of diabetes and its complications...