S A Jamal

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. doi The clinical utility of FRAX to discriminate fracture status in men and women with chronic kidney disease
    S A Jamal
    University of Toronto and Women s College Research Institute, 790 Bay Street, 7th Floor, Toronto, Ontario, M5G 1N8, Canada
    Osteoporos Int 25:71-6. 2014
  2. pmc Nitrates and bone turnover (NABT) - trial to select the best nitrate preparation: study protocol for a randomized controlled trial
    Roxana C Bucur
    Women s College Research Institute and Department of Medicine, Women s College Hospital, The University of Toronto, Toronto, Ontario, Canada
    Trials 14:284. 2013
  3. doi Effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease: an updated systematic review and meta-analysis
    Sophie A Jamal
    Division of Endocrinology and Metabolism, Women s College Hospital, University of Toronto, Toronto, ON, Canada
    Lancet 382:1268-77. 2013
  4. ncbi The effects of organic nitrates on osteoporosis: a systematic review
    S A Jamal
    Women s College Research Institute, 790 Bay Street, 7th Floor, Toronto, Ontario M5G 1N8, Canada
    Osteoporos Int 24:763-70. 2013
  5. doi Secondary and tertiary hyperparathyroidism
    Sophie A Jamal
    University of Toronto, Women s College Research Institute, Toronto, Ontario, Canada
    J Clin Densitom 16:64-8. 2013
  6. ncbi Bone mineral density by DXA and HR pQCT can discriminate fracture status in men and women with stages 3 to 5 chronic kidney disease
    S A Jamal
    Women s College Research Institute, 790 Bay Street, Suite 725, Toronto, ON, M5G 1N8, Canada
    Osteoporos Int 23:2805-13. 2012
  7. doi Bone and kidney disease: diagnostic and therapeutic implications
    Sophie A Jamal
    University of Toronto, Women s College Hospital, Ontario, Canada
    Curr Rheumatol Rep 14:217-23. 2012
  8. doi Fracture risk assessment in patients with chronic kidney disease
    S A Jamal
    Department of Medicine, University of Toronto, Toronto, ON, Canada
    Osteoporos Int 23:1191-8. 2012
  9. doi Nitric oxide donors for the treatment of osteoporosis
    Sophie A Jamal
    Multidisciplinary Osteoporosis Research Program, Women s College Hospital, 790 Bay Street, 7th Floor, Toronto, ON M5G 1N8, Canada
    Curr Osteoporos Rep 10:86-92. 2012
  10. pmc Fracture Risk Assessment in Chronic Kidney Disease, Prospective Testing Under Real World Environments (FRACTURE): a prospective study
    Sarah L West
    Multidisciplinary Osteoporosis Program, Women s College Hospital, and Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
    BMC Nephrol 11:17. 2010

Detail Information

Publications39

  1. doi The clinical utility of FRAX to discriminate fracture status in men and women with chronic kidney disease
    S A Jamal
    University of Toronto and Women s College Research Institute, 790 Bay Street, 7th Floor, Toronto, Ontario, M5G 1N8, Canada
    Osteoporos Int 25:71-6. 2014
    ..In adults with CKD, FRAX was able to discriminate fracture status but performed no better than BMD alone...
  2. pmc Nitrates and bone turnover (NABT) - trial to select the best nitrate preparation: study protocol for a randomized controlled trial
    Roxana C Bucur
    Women s College Research Institute and Department of Medicine, Women s College Hospital, The University of Toronto, Toronto, Ontario, Canada
    Trials 14:284. 2013
    ..Ascertaining which nitrate formulation this may be is the purpose of the current study...
  3. doi Effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease: an updated systematic review and meta-analysis
    Sophie A Jamal
    Division of Endocrinology and Metabolism, Women s College Hospital, University of Toronto, Toronto, ON, Canada
    Lancet 382:1268-77. 2013
    ..We aimed to update our meta-analysis on the effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease...
  4. ncbi The effects of organic nitrates on osteoporosis: a systematic review
    S A Jamal
    Women s College Research Institute, 790 Bay Street, 7th Floor, Toronto, Ontario M5G 1N8, Canada
    Osteoporos Int 24:763-70. 2013
    ..Headaches were the most common adverse event among women taking nitrates. No studies have reported on fracture efficacy. Further research is needed before recommending organic nitrates for the treatment of postmenopausal osteoporosis...
  5. doi Secondary and tertiary hyperparathyroidism
    Sophie A Jamal
    University of Toronto, Women s College Research Institute, Toronto, Ontario, Canada
    J Clin Densitom 16:64-8. 2013
    ..The etiology and treatment of secondary hyperparathyroidism is relatively straightforward whereas data on the management of tertiary hyperparathyroidism is limited to a few small trials with short follow-up...
  6. ncbi Bone mineral density by DXA and HR pQCT can discriminate fracture status in men and women with stages 3 to 5 chronic kidney disease
    S A Jamal
    Women s College Research Institute, 790 Bay Street, Suite 725, Toronto, ON, M5G 1N8, Canada
    Osteoporos Int 23:2805-13. 2012
    ..Both tests were able to discriminate fracture status. Further, the addition of HR pQCT measurements to DXA measurements did not improve fracture discrimination...
  7. doi Bone and kidney disease: diagnostic and therapeutic implications
    Sophie A Jamal
    University of Toronto, Women s College Hospital, Ontario, Canada
    Curr Rheumatol Rep 14:217-23. 2012
    ..Bone biopsy may be required, and most treatments, if used, would be off label. Overall, the diagnosis and treatment of bone disease in patients with CKD require further research...
  8. doi Fracture risk assessment in patients with chronic kidney disease
    S A Jamal
    Department of Medicine, University of Toronto, Toronto, ON, Canada
    Osteoporos Int 23:1191-8. 2012
    ..Further prospective studies to identify noninvasive measures of bone strength that can be used for fracture risk assessment are needed...
  9. doi Nitric oxide donors for the treatment of osteoporosis
    Sophie A Jamal
    Multidisciplinary Osteoporosis Research Program, Women s College Hospital, 790 Bay Street, 7th Floor, Toronto, ON M5G 1N8, Canada
    Curr Osteoporos Rep 10:86-92. 2012
    ....
  10. pmc Fracture Risk Assessment in Chronic Kidney Disease, Prospective Testing Under Real World Environments (FRACTURE): a prospective study
    Sarah L West
    Multidisciplinary Osteoporosis Program, Women s College Hospital, and Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
    BMC Nephrol 11:17. 2010
    ..Our study aims to identify prognostic factors for bone loss and fractures in patients with stages 3 to 5 CKD...
  11. doi Effects of denosumab on fracture and bone mineral density by level of kidney function
    Sophie A Jamal
    Department of Medicine, University of Toronto, Ontario, Canada
    J Bone Miner Res 26:1829-35. 2011
    ..It is concluded that DMAb is effective at reducing fracture risk and is not associated with an increase in adverse events among patients with impaired kidney function...
  12. doi Effect of nitroglycerin ointment on bone density and strength in postmenopausal women: a randomized trial
    Sophie A Jamal
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    JAMA 305:800-7. 2011
    ..Nitroglycerin stimulates bone formation and inhibits bone resorption, is inexpensive, and is widely available. Its effects on bone density, bone structure, and bone strength are unknown...
  13. doi Bone mass measurements in men and women with chronic kidney disease
    Sophie A Jamal
    Women s College Hospital, University of Toronto, Toronto, Ontario, Canada
    Curr Opin Nephrol Hypertens 19:343-8. 2010
    ..Bone mass measurements are commonly used to assess fracture risk in the general population, but the utility of these measurements in patients with CKD is unclear...
  14. doi Kidney function and rate of bone loss at the hip and spine: the Canadian Multicentre Osteoporosis Study
    Sophie A Jamal
    University of Toronto, Toronto, Canada
    Am J Kidney Dis 55:291-9. 2010
    ..The relationship between kidney function and bone loss is unclear...
  15. doi Nitrate use and changes in bone mineral density: the Canadian Multicentre Osteoporosis Study
    S A Jamal
    Medicine, University of Toronto, Toronto, ON, Canada
    Osteoporos Int 20:737-44. 2009
    ..Subjects reporting nitrate use had increased BMD compared with non-users, confirming that nitrates have positive BMD effects in women and men...
  16. ncbi Bone density and heel ultrasound testing do not identify patients with dialysis-dependent renal failure who have had fractures
    Sophie A Jamal
    Division of Endocrinology, Multidisciplinary Osteoporosis Program, Women s College Ambulatory Care Centre, Toronto, Ontario, Canada
    Am J Kidney Dis 39:843-9. 2002
    ..Prospective studies to determine the optimal method of identifying patients with dialysis-dependent renal failure at high risk for fracture are needed...
  17. ncbi Isosorbide mononitrate increases bone formation and decreases bone resorption in postmenopausal women: a randomized trial
    Sophie A Jamal
    Department of Medicine, Division of Endocrinology and Metabolism, St Michael s Hospital, University of Toronto, Toronto, Ontario M5C 2T2, Canada
    J Bone Miner Res 19:1512-7. 2004
    ..After 3 months, women randomized to ISMO had a greater decrease in bone resorption and a greater increase in bone formation compared with placebo. NO donors may prevent postmenopausal bone loss...
  18. ncbi Clinical utility of laboratory testing in women with osteoporosis
    Sophie A Jamal
    Department of Medicine, Division of Endocrinology and Metabolism, St Michael s Hospital, University of Toronto, 61 Queen Street East, Toronto, Ontario M5C 2T2, Canada
    Osteoporos Int 16:534-40. 2005
    ..4 (95% CI: 1.3-1.6). Our data suggests that when assessing healthy women with osteoporosis ordering a routine panel of laboratory tests is not useful but measuring TSH may be informative...
  19. ncbi Hyperhomocysteinaemia and aortic calcification are associated with fractures in patients on haemodialysis
    S A Jamal
    Division of Endocrinology and Metabolism, St Michael s Hospital, Toronto, Canada
    QJM 98:575-9. 2005
    ..Fractures and atherosclerosis are common in patients with renal failure; this may be due to hyperhomocysteinemia...
  20. ncbi Cortical pQCT measures are associated with fractures in dialysis patients
    Sophie A Jamal
    Department of Medicine, Division of Endocrinology and Metabolism, St Michael s Hospital, University of Toronto, Toronto, Canada
    J Bone Miner Res 21:543-8. 2006
    ..To determine if pQCT could identify HD patients with fractures, we conducted a cross-sectional study in 52 men and women on HD. We found that cortical, but not trabecular, pQCT measures were associated with fractures...
  21. ncbi Impaired muscle strength is associated with fractures in hemodialysis patients
    S A Jamal
    Department of Medicine, Division of Endocrinology and Metabolism, St Michael s Hospital, University of Toronto, Toronto, ON, Canada
    Osteoporos Int 17:1390-7. 2006
    ..Fractures are extremely common among hemodialysis (HD) patients...
  22. ncbi Alendronate treatment in women with normal to severely impaired renal function: an analysis of the fracture intervention trial
    Sophie A Jamal
    Division of Endocrinology, St Michael s Hospital and the University of Toronto, Toronto, Ont, Canada
    J Bone Miner Res 22:503-8. 2007
    ..There was no increase in adverse events among women with impaired renal function treated with alendronate. Alendronate is safe and effective among this group of women with reduced renal function...
  23. ncbi Low bone mineral density and fractures in long-term hemodialysis patients: a meta-analysis
    Sophie A Jamal
    St Michael s Hospital, Toronto, Ontario, Canada
    Am J Kidney Dis 49:674-81. 2007
    ..The association between bone mineral density (BMD) by dual-energy X-ray absorptiometry (DXA) and fracture in patients with stage 5 chronic kidney disease (CKD) is unclear...
  24. doi Risk factors for low bone mass in healthy 40-60 year old women: a systematic review of the literature
    E J Waugh
    Osteoporosis Research Program, Women s College Hospital, Toronto, ON, Canada
    Osteoporos Int 20:1-21. 2009
    ..The use of body weight to identify high risk women may reduce unnecessary BMD testing in this age group...
  25. ncbi Practice patterns in the diagnosis and treatment of osteoporosis after a fragility fracture: a systematic review
    V Elliot-Gibson
    Mobility Program, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Osteoporos Int 15:767-78. 2004
    ..Barriers included the cost of therapies, time and cost of resources for diagnosis, concerns about medications, and the lack of clarity regarding the responsibility to undertake this care...
  26. ncbi A clinical prediction rule to identify premenopausal women with low bone mass
    G A Hawker
    Division of Rheumatology, Women s College Ambulatory Care Centre, The University of Toronto, Ontario, Canada
    Osteoporos Int 13:400-6. 2002
    ..This suggests that a simple risk factor assessment can identify most young women with low peak bone mass. Early intervention in this group of women may reduce the risk for osteoporosis in later life...
  27. doi The effects of exercise and physical activity participation on bone mass and geometry in postmenopausal women: a systematic review of pQCT studies
    C J Hamilton
    Women s College Hospital, Toronto, ON, Canada
    Osteoporos Int 21:11-23. 2010
    ....
  28. ncbi The presence of both an energy deficiency and estrogen deficiency exacerbate alterations of bone metabolism in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
    Bone 43:140-8. 2008
    ..Bone loss in amenorrheic athletes has been attributed to energy deficiency-related suppression of bone formation, but not increased resorption despite hypoestrogenism...
  29. ncbi Effective initiation of osteoporosis diagnosis and treatment for patients with a fragility fracture in an orthopaedic environment
    Earl R Bogoch
    St Michael s Hospital, University of Toronto, 55 Queen Street East, Suite 800, Toronto, ON M5C 1R6, Canada
    J Bone Joint Surg Am 88:25-34. 2006
    ....
  30. doi Effects of calcium on cardiovascular events in patients with kidney disease and in a healthy population
    Sarah L West
    Multidisciplinary Osteoporosis Program, Women s College Hospital, Toronto, Ontario, Canada
    Clin J Am Soc Nephrol 5:S41-7. 2010
    ..The etiology of vascular calcification and the specific role calcium supplementation may play in accelerating calcification have not been fully elucidated...
  31. doi Associations between leisure physical activity participation and cortical bone mass and geometry at the radius and tibia in a Canadian cohort of postmenopausal women
    Celeste J Hamilton
    University of Toronto, Toronto ON, Canada
    Bone 46:774-9. 2010
    ....
  32. doi The effects of calcium-based versus non-calcium-based phosphate binders on mortality among patients with chronic kidney disease: a meta-analysis
    Sophie A Jamal
    University of Toronto, Division of Endocrinology and Metabolism, Women s College Hospital, Toronto, Canada
    Nephrol Dial Transplant 24:3168-74. 2009
    ..The effects of calcium compared with non-calcium-based phosphate binders on mortality, cardiovascular events and vascular calcification in patients with chronic kidney disease (CKD) are unknown...
  33. doi Strategies to reverse bone loss in women with functional hypothalamic amenorrhea: a systematic review of the literature
    J D Vescovi
    Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Science, University of Toronto, Toronto, ON, Canada M5S 2W6
    Osteoporos Int 19:465-78. 2008
    ....
  34. ncbi The risk of hip fractures in older individuals with diabetes: a population-based study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Diabetes Care 30:835-41. 2007
    ..However, they may still be at increased risk for hip fractures. Using population-based Ontario health care data, we compared the risk of hip fractures among men and women with and without diabetes...
  35. ncbi Renal function and risk of hip and vertebral fractures in older women
    Kristine E Ensrud
    Center for Chronic Disease Outcomes Research, VA Medical Center, Minneapolis, MN 55417, USA
    Arch Intern Med 167:133-9. 2007
    ..An increased rate of hip fractures has been reported in patients with end-stage renal disease, but the effect of less severe renal dysfunction on fracture risk is uncertain...
  36. pmc Low bone mineral density and fracture burden in postmenopausal women
    Ann Cranney
    Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ont
    CMAJ 177:575-80. 2007
    ..5 or less), and to contrast fracture patterns among women 50 to 64 years of age with those among women 65 years of age and older...
  37. pmc The effect of raloxifene treatment in postmenopausal women with CKD
    Areef Ishani
    Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, and Department of Medicine and Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55417, USA
    J Am Soc Nephrol 19:1430-8. 2008
    ..In conclusion, raloxifene increases BMD at both the hip and the spine and reduces the risk for vertebral fractures among individuals with CKD. The effect ofraloxifene on hip BMD is greater among those with mild to moderate CKD...
  38. ncbi Use of statins and fracture: results of 4 prospective studies and cumulative meta-analysis of observational studies and controlled trials
    Douglas C Bauer
    Department of Medicine, University of California, San Francisco 94105, USA
    Arch Intern Med 164:146-52. 2004
    ....