Research Topics
Species | Jonathan I IzawaSummaryAffiliation: University of Western Ontario Country: Canada Publications
| Collaborators
|
Detail Information
Publications
Prognostic variables in adult Wilms tumourJonathan I Izawa
Department of Surgery, London Health Sciences Centre, London, Ont
Can J Surg 51:252-6. 2008..To identify outcomes and prognostic variables that predict survival outcomes in adult Wilms tumour patients...
Do all patients with high-grade prostatic intraepithelial neoplasia on initial prostatic biopsy eventually progress to clinical prostate cancer?Jonathan I Izawa
Department of Surgery and Oncology, University of Western Ontario, London, Ontario, Canada
BJU Int 96:320-3. 2005....- Molecular targeted enhanced ultrasound imaging of flk1 reveals diagnosis and prognosis potential in a genetically engineered mouse prostate cancer modelJim W Xuan
Lawson Health Research Institute, Robarts Research Institute, London Regional Cancer Program, University of Western Ontario, London, ON
Mol Imaging 8:209-20. 2009.... - Increased intratumoral expression of prostate secretory protein of 94 amino acids predicts for worse disease recurrence and progression after radical prostatectomy in patients with prostate cancerAndrew R Girvan
Department of Surgery, Division of Urology, Clinical Cancer Research Program, The London Regional Cancer Centre, London, Ontario, Canada
Urology 65:719-23. 2005..046) and disease-free survival (P = 0.049). CONCLUSIONS: PSP94 expression in radical prostatectomy tumor specimens appears to be associated with worsened survival outcomes and may provide additional prognostic information... - A new three-dimensional ultrasound microimaging technology for preclinical studies using a transgenic prostate cancer mouse modelLauren A Wirtzfeld
Biomedical Engineering Graduate Program, University of Western Ontario, Canada
Cancer Res 65:6337-45. 2005.... - Functional neoangiogenesis imaging of genetically engineered mouse prostate cancer using three-dimensional power Doppler ultrasoundJim W Xuan
Department of Surgery, University of Western Ontario, London, Canada
Cancer Res 67:2830-9. 2007..Three-dimensional power Doppler imaging is completely noninvasive and will facilitate basic and preclinical research on neoangiogenesis in live animal models... - Intraoperative laparoscopic renal ultrasonography: use in advanced laparoscopic renal surgeryLuke M Fazio
Department of Surgery, Division of Urology, University of Western Ontario, London, Ontario, Canada
Urology 68:723-7. 2006..In a number of situations, it is an essential surgical tool. With expanding indications for laparoscopic surgery, the indications for ILUS continue to grow... 
Ghrelin receptor as a novel imaging target for prostatic neoplasmsChen Lu
Translational Prostate Cancer Research Group, London Regional Cancer Program, London, Ontario, Canada
Prostate 72:825-33. 2012..Imaging probes that target receptors for ghrelin may delineate PCas from benign disease. The specificity of a novel ghrelin-imaging probe for PCa over normal tissue or benign disease was assessed...- Metallothionein expression as prognostic factor for transitional cell carcinoma of bladderYasuto Yamasaki
Division of Urology, Department of Surgery, University of Western Ontario, London, Ontario, Canada
Urology 67:530-5. 2006..This finding requires additional validation using other data sets... - Location of a positive biopsy as a predictor of surgical margin status and extraprostatic disease in radical prostatectomyNaji J Touma
Surgery, Division of Urology, University of Western Ontario, London, Ontario, Canada
BJU Int 97:259-62. 2006..02). CONCLUSION: A positive biopsy core at the base appears to correlate with a positive basal SM and EPE. A positive basal SM correlates with EPE at a higher rate than apical SMs... - How long can patients with renal cell carcinoma wait for surgery without compromising pathological outcomes?Carlos H Martinez
Division of Urology, Department of Surgery, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON Division of Surgical Oncology, Department of Oncology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON
Can Urol Assoc J 5:E148-51. 2011..We analyzed surgical waiting time for RCC patients to see if there was an adverse impact on pathological characteristics... - Temporal-based needle segmentation algorithm for transrectal ultrasound prostate biopsy proceduresDerek W Cool
Imaging Research Laboratories, Robarts Research Institute, University of Western Ontario, London, Ontario N6A 5K8, Canada
Med Phys 37:1660-73. 2010.... - A novel knock-in prostate cancer model demonstrates biology similar to that of human prostate cancer and suitable for preclinical studiesManal Y Gabril
Department of Surgery, University of Western Ontario, London, ON N6A 4G5, Canada
Mol Ther 11:348-62. 2005..Due to the similarities between human CaP tumors and the PSP-KIMAP tumors, this preclinical model may supplement the current transgenic models to study CaP more accurately... - Clinically significant prostate cancer found incidentally in radical cystoprostatectomy specimensMazen Abdelhady
University of Western Ontario, Surgery and Oncology, London, Ontario, Canada
BJU Int 99:326-9. 2007.... - Characterization of the oncogenic activity of the novel TRIM59 gene in mouse cancer modelsFatma Valiyeva
Lawson Health Research Institute, University of Western Ontario, 375 South Street, London, ON, N6A 4G5, Canada
Mol Cancer Ther 10:1229-40. 2011..The finding of a possible novel oncogene in animal models will implicate a novel strategy for diagnosis, prognosis, and therapy for cancer... - Transitional-cell carcinoma recurrence rate after nephroureterectomy in patients who undergo open excision of bladder cuff v transurethral incision of the ureteral orificeRaymond Ko
Division of Urology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada
J Endourol 21:730-4. 2007..Two treatment options to detach the distal ureter are open cystotomy (OC) and excision of a bladder cuff or transurethral incision of the ureteral orifice (TUIUO). We compared the clinico-pathologic outcomes of these two techniques... - Primary PEComa of the bladder treated with primary excision and adjuvant interferon-alpha immunotherapy: a case reportJeremy R Parfitt
Department of Pathology, London Health Sciences Centre and University of Western Ontario, London, Canada
BMC Urol 6:20. 2006..Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms of uncertain malignant potential, which have in common the co-expression of muscle and melanocytic immunohistochemical markers... - Repeat prostate biopsy accuracy: simulator-based comparison of two- and three-dimensional transrectal US modalitiesDerek W Cool
Imaging Research Laboratories, Robarts Research Institute, University of Western Ontario, London, Canada
Radiology 254:587-94. 2010.... - Cumulative summation graphs are a useful tool for monitoring positive surgical margin rates in robot-assisted radical prostatectomyAndrew K Williams
Division of Urology, Department of Surgery, University of Western Ontario, London, ON, Canada
BJU Int 107:1648-52. 2011..To explore the usefulness of cumulative summation (CUSUM) graphs for monitoring positive surgical margin (PSM) rates during a surgeon's transition from open to robot-assisted radical prostatectomy (RARP)... - Salvage radiotherapy following radical prostatectomyVenu Chalasani
Departments of Surgery and Oncology, Divisions of Urology and Surgical Oncology, The Schulich School of Medicine and Dentistry, University of Western Ontario, Ontario, Canada
Int J Urol 16:31-6. 2009..Salvage radiotherapy can provide a durable response when given early, and patients with recurrent disease should be considered for treatment or enrolment in clinical trials... - Quality assurance and benchmarking for radical cystectomy: monitoring early complications and mortality using cumulative summation chartsVenu Chalasani
Departments of Surgery and Oncology, Divisions of Urology and Surgical Oncology, Schulich School of Medicine and Dentistry, London, Ontario, Canada
J Urol 181:1581-6. 2009..In this study we used cumulative summation charts for quality assurance in radical cystectomies... - Development and validation of a virtual reality transrectal ultrasound guided prostatic biopsy simulatorVenu Chalasani
Departments of Surgery and Oncology, Divisions of Urology and Surgical Oncology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON
Can Urol Assoc J 5:19-26. 2011..We present the design, reliability, face, content and construct validity testing of a virtual reality simulator for transrectal ultrasound (TRUS), which allows doctors-in-training to perform multiple different biopsy schemes... - Metastatic Merkel cell tumor to the prostate and bladderDouglas P Mack
Department of Surgery, Division of Urology, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada
Urology 64:156-8. 2004..Efforts should be made to optimize the patient's quality of life with the finding of metastatic Merkel cell carcinoma to the bladder or prostate until better adjuvant therapies are identified... - Total pelvic exenteration for rectal cancer: outcomes and prognostic factorsTrustin S Domes
Division of Urology, Department of Medicine, Schulich School of Medicine, University of Western Ontario, London, Ontario
Can J Surg 54:387-93. 2011..To perform complete resection of locally advanced and recurrent rectal carcinoma, total pelvic exenteration (TPE) may be attempted. We identified disease-related outcomes and prognostic factors... - Treatment of radiation failure in prostate cancerJoseph L Chin
University of Western Ontario, London, Ontario, Canada
Can J Urol 13:48-51. 2006..Management of patients who have failed of local radiotherapy remains a challenge. Herein the current therapeutic options are reviewed... - Timing cystectomy and perioperative chemotherapy in the treatment of muscle invasive bladder cancerJonathan I Izawa
Department of Surgery, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada
Can J Urol 13:48-53. 2006..Improved preoperative staging and understanding of tumor biology are required to optimize the multimodality treatment of TCC... - Plasma osteopontin levels are predictive of disease stage in patients with transitional cell carcinoma of the bladderCelina Ang
Department of Surgery, University of Western Ontario, London, Ontario, Canada
BJU Int 96:803-5. 2005..021). CONCLUSIONS: Plasma osteopontin levels increase with tumour stage in TCC of the bladder. These findings suggest that larger, more extended studies on plasma osteopontin levels in patients with TCC are warranted... - Laparoscopic versus open partial nephrectomyKenneth A Beasley
Division of Urology, University of Western Ontario, London, Ontario, Canada
Urology 64:458-61. 2004..Long-term results on cancer control in patients treated with LPN continue to be assessed... - Characterization of initiation of angiogenesis in early stages of prostate adenocarcinoma development and progression in a transgenic murine modelManal Gabril
Department of Surgery, London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada
Urology 64:1233-7. 2004.... - Current status of local salvage therapies following radiation failure for prostate cancerNaji J Touma
Division of Urology, University of Western Ontario, London, Ontario, Canada
J Urol 173:373-9. 2005..The study of brachytherapy remains in its infancy and the efficacy of this modality remains to be determined... - Malignant neoplasm of perivascular epithelioid cells of the liverJeremy R Parfitt
Departments of Pathology, London Health Sciences Centre and University of Western Ontario, London, Ontario, Canada
Arch Pathol Lab Med 130:1219-22. 2006.... - The prognostic significance of metastatic perivesical lymph nodes identified in radical cystectomy specimens for transitional cell carcinoma of the bladderAnthony J Bella
Department of Surgery, London Regional Cancer Centre, University of Western Ontario, London, Canada
J Urol 170:2253-7. 2003..025, respectively). CONCLUSIONS: Metastases to PVLN appear to confer a significantly worse prognosis for patients undergoing radical cystectomy. Patients with identifiable metastatic PVLN may benefit from early adjuvant therapies... - Bladder perforation after immediate postoperative intravesical instillation of mitomycin CDarwin Lim
Departments of Surgery and Oncology, Divisions of Urology and Surgical Oncology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON
Can Urol Assoc J 4:E1-3. 2010..We report our own experience of a male patient with bladder perforation after an early instillation of a single dose of MMC. In this case, systemic toxicity occurred which required intensive care after surgical repair... - Radical cystectomy for the treatment of T1 bladder cancer: the Canadian Bladder Cancer Network experienceVenu Chalasani
Departments of Surgery and Oncology, Divisions of Urology and Surgical Oncology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON
Can Urol Assoc J 5:83-7. 2011..We present our data from a large, multi-institutional, contemporary Canadian series of patients who underwent radical cystectomy for clinical T1 bladder cancer in a single-payer health care system... - Histological changes in prostate biopsies after salvage cryotherapy: effect of chronology and the method of biopsyJonathan I Izawa
Department of Urology, The University of Texas, M. D. Anderson Center, Houston, TX 77030, USA
BJU Int 98:554-8. 2006..CONCLUSIONS: Tissue cryo-injury and reactive changes last for >1 year; more extensive cryo-injury suggests more effective cancer ablation. A long-term follow-up is necessary, as prostate cancer might remain indolent for >1 year... - Clinical presentation and outcome of high-grade urinary bladder leiomyosarcoma in adultsCharles J Rosser
Department of Urology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4009, USA
Urology 61:1151-5. 2003..0%... - Incomplete glandular ablation after salvage cryotherapy for recurrent prostate cancer after radiotherapyJonathan I Izawa
Department of Urology, The University of Texas M. D. Anderson Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 56:468-72. 2003..The finding of atypical or normal epithelial tissue in biopsy specimens after salvage cryotherapy is not predictive of biochemical failure... - Salvage cryotherapy for recurrent prostate cancer after radiotherapy: variables affecting patient outcomeJonathan I Izawa
Department of Urology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
J Clin Oncol 20:2664-71. 2002..The subset of patients cured by salvage cryotherapy seems to be small, and patient selection is important... - Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude miceTakashi Karashima
Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston 77030, USA
Clin Cancer Res 8:1253-64. 2002..The simultaneous administration of paclitaxel enhanced this effect...