Jonathan I Izawa

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. pmc Prognostic variables in adult Wilms tumour
    Jonathan I Izawa
    Department of Surgery, London Health Sciences Centre, London, Ont
    Can J Surg 51:252-6. 2008
  2. ncbi request reprint Do all patients with high-grade prostatic intraepithelial neoplasia on initial prostatic biopsy eventually progress to clinical prostate cancer?
    Jonathan I Izawa
    Department of Surgery and Oncology, University of Western Ontario, London, Ontario, Canada
    BJU Int 96:320-3. 2005
  3. ncbi request reprint Molecular targeted enhanced ultrasound imaging of flk1 reveals diagnosis and prognosis potential in a genetically engineered mouse prostate cancer model
    Jim W Xuan
    Lawson Health Research Institute, Robarts Research Institute, London Regional Cancer Program, University of Western Ontario, London, ON
    Mol Imaging 8:209-20. 2009
  4. ncbi request reprint Increased intratumoral expression of prostate secretory protein of 94 amino acids predicts for worse disease recurrence and progression after radical prostatectomy in patients with prostate cancer
    Andrew R Girvan
    Department of Surgery, Division of Urology, Clinical Cancer Research Program, The London Regional Cancer Centre, London, Ontario, Canada
    Urology 65:719-23. 2005
  5. ncbi request reprint Functional neoangiogenesis imaging of genetically engineered mouse prostate cancer using three-dimensional power Doppler ultrasound
    Jim W Xuan
    Department of Surgery, University of Western Ontario, London, Canada
    Cancer Res 67:2830-9. 2007
  6. ncbi request reprint Intraoperative laparoscopic renal ultrasonography: use in advanced laparoscopic renal surgery
    Luke M Fazio
    Department of Surgery, Division of Urology, University of Western Ontario, London, Ontario, Canada
    Urology 68:723-7. 2006
  7. ncbi request reprint A new three-dimensional ultrasound microimaging technology for preclinical studies using a transgenic prostate cancer mouse model
    Lauren A Wirtzfeld
    Biomedical Engineering Graduate Program, University of Western Ontario, Canada
    Cancer Res 65:6337-45. 2005
  8. doi request reprint Ghrelin receptor as a novel imaging target for prostatic neoplasms
    Chen Lu
    Translational Prostate Cancer Research Group, London Regional Cancer Program, London, Ontario, Canada
    Prostate 72:825-33. 2012
  9. ncbi request reprint Location of a positive biopsy as a predictor of surgical margin status and extraprostatic disease in radical prostatectomy
    Naji J Touma
    Surgery, Division of Urology, University of Western Ontario, London, Ontario, Canada
    BJU Int 97:259-62. 2006
  10. ncbi request reprint Metallothionein expression as prognostic factor for transitional cell carcinoma of bladder
    Yasuto Yamasaki
    Division of Urology, Department of Surgery, University of Western Ontario, London, Ontario, Canada
    Urology 67:530-5. 2006

Collaborators

Detail Information

Publications40

  1. pmc Prognostic variables in adult Wilms tumour
    Jonathan I Izawa
    Department of Surgery, London Health Sciences Centre, London, Ont
    Can J Surg 51:252-6. 2008
    ..To identify outcomes and prognostic variables that predict survival outcomes in adult Wilms tumour patients...
  2. ncbi request reprint Do all patients with high-grade prostatic intraepithelial neoplasia on initial prostatic biopsy eventually progress to clinical prostate cancer?
    Jonathan I Izawa
    Department of Surgery and Oncology, University of Western Ontario, London, Ontario, Canada
    BJU Int 96:320-3. 2005
    ....
  3. ncbi request reprint Molecular targeted enhanced ultrasound imaging of flk1 reveals diagnosis and prognosis potential in a genetically engineered mouse prostate cancer model
    Jim W Xuan
    Lawson Health Research Institute, Robarts Research Institute, London Regional Cancer Program, University of Western Ontario, London, ON
    Mol Imaging 8:209-20. 2009
    ....
  4. ncbi request reprint Increased intratumoral expression of prostate secretory protein of 94 amino acids predicts for worse disease recurrence and progression after radical prostatectomy in patients with prostate cancer
    Andrew R Girvan
    Department of Surgery, Division of Urology, Clinical Cancer Research Program, The London Regional Cancer Centre, London, Ontario, Canada
    Urology 65:719-23. 2005
    ..To examine the impact of prostate secretory protein of 94 amino acids (PSP94) expression within the primary tumor on disease recurrence and progression using radical prostatectomy specimens from patients with adenocarcinoma of the prostate...
  5. ncbi request reprint Functional neoangiogenesis imaging of genetically engineered mouse prostate cancer using three-dimensional power Doppler ultrasound
    Jim W Xuan
    Department of Surgery, University of Western Ontario, London, Canada
    Cancer Res 67:2830-9. 2007
    ..Three-dimensional power Doppler imaging is completely noninvasive and will facilitate basic and preclinical research on neoangiogenesis in live animal models...
  6. ncbi request reprint Intraoperative laparoscopic renal ultrasonography: use in advanced laparoscopic renal surgery
    Luke M Fazio
    Department of Surgery, Division of Urology, University of Western Ontario, London, Ontario, Canada
    Urology 68:723-7. 2006
    ..ILUS has been used to facilitate advanced laparoscopic surgery, but only limited descriptions of the indications for its use have been published...
  7. ncbi request reprint A new three-dimensional ultrasound microimaging technology for preclinical studies using a transgenic prostate cancer mouse model
    Lauren A Wirtzfeld
    Biomedical Engineering Graduate Program, University of Western Ontario, Canada
    Cancer Res 65:6337-45. 2005
    ....
  8. doi request reprint Ghrelin receptor as a novel imaging target for prostatic neoplasms
    Chen Lu
    Translational Prostate Cancer Research Group, London Regional Cancer Program, London, Ontario, Canada
    Prostate 72:825-33. 2012
    ..Imaging probes that target receptors for ghrelin may delineate PCas from benign disease. The specificity of a novel ghrelin-imaging probe for PCa over normal tissue or benign disease was assessed...
  9. ncbi request reprint Location of a positive biopsy as a predictor of surgical margin status and extraprostatic disease in radical prostatectomy
    Naji J Touma
    Surgery, Division of Urology, University of Western Ontario, London, Ontario, Canada
    BJU Int 97:259-62. 2006
    ..To investigate whether the location of preoperative biopsy positive cores can identify patients at higher risk of a positive surgical margin (SM) and extraprostatic extension (EPE) at radical retropubic prostatectomy (RRP)...
  10. ncbi request reprint Metallothionein expression as prognostic factor for transitional cell carcinoma of bladder
    Yasuto Yamasaki
    Division of Urology, Department of Surgery, University of Western Ontario, London, Ontario, Canada
    Urology 67:530-5. 2006
    ..To determine whether metallothionein (MT) protein expression is associated with clinical outcomes in patients with transitional cell carcinoma (TCC) of the bladder...
  11. pmc How long can patients with renal cell carcinoma wait for surgery without compromising pathological outcomes?
    Carlos H Martinez
    Division of Urology, Department of Surgery, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON Division of Surgical Oncology, Department of Oncology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON
    Can Urol Assoc J 5:E148-51. 2011
    ..We analyzed surgical waiting time for RCC patients to see if there was an adverse impact on pathological characteristics...
  12. ncbi request reprint Temporal-based needle segmentation algorithm for transrectal ultrasound prostate biopsy procedures
    Derek W Cool
    Imaging Research Laboratories, Robarts Research Institute, University of Western Ontario, London, Ontario N6A 5K8, Canada
    Med Phys 37:1660-73. 2010
    ....
  13. ncbi request reprint A novel knock-in prostate cancer model demonstrates biology similar to that of human prostate cancer and suitable for preclinical studies
    Manal Y Gabril
    Department of Surgery, University of Western Ontario, London, ON N6A 4G5, Canada
    Mol Ther 11:348-62. 2005
    ..Due to the similarities between human CaP tumors and the PSP-KIMAP tumors, this preclinical model may supplement the current transgenic models to study CaP more accurately...
  14. doi request reprint Characterization of the oncogenic activity of the novel TRIM59 gene in mouse cancer models
    Fatma Valiyeva
    Lawson Health Research Institute, University of Western Ontario, 375 South Street, London, ON, N6A 4G5, Canada
    Mol Cancer Ther 10:1229-40. 2011
    ..The finding of a possible novel oncogene in animal models will implicate a novel strategy for diagnosis, prognosis, and therapy for cancer...
  15. ncbi request reprint Transitional-cell carcinoma recurrence rate after nephroureterectomy in patients who undergo open excision of bladder cuff v transurethral incision of the ureteral orifice
    Raymond Ko
    Division of Urology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada
    J Endourol 21:730-4. 2007
    ..Two treatment options to detach the distal ureter are open cystotomy (OC) and excision of a bladder cuff or transurethral incision of the ureteral orifice (TUIUO). We compared the clinico-pathologic outcomes of these two techniques...
  16. ncbi request reprint Clinically significant prostate cancer found incidentally in radical cystoprostatectomy specimens
    Mazen Abdelhady
    University of Western Ontario, Surgery and Oncology, London, Ontario, Canada
    BJU Int 99:326-9. 2007
    ....
  17. pmc Primary PEComa of the bladder treated with primary excision and adjuvant interferon-alpha immunotherapy: a case report
    Jeremy R Parfitt
    Department of Pathology, London Health Sciences Centre and University of Western Ontario, London, Canada
    BMC Urol 6:20. 2006
    ..Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms of uncertain malignant potential, which have in common the co-expression of muscle and melanocytic immunohistochemical markers...
  18. doi request reprint Repeat prostate biopsy accuracy: simulator-based comparison of two- and three-dimensional transrectal US modalities
    Derek W Cool
    Imaging Research Laboratories, Robarts Research Institute, University of Western Ontario, London, Canada
    Radiology 254:587-94. 2010
    ....
  19. doi request reprint Cumulative summation graphs are a useful tool for monitoring positive surgical margin rates in robot-assisted radical prostatectomy
    Andrew K Williams
    Division of Urology, Department of Surgery, University of Western Ontario, London, ON, Canada
    BJU Int 107:1648-52. 2011
    ..To explore the usefulness of cumulative summation (CUSUM) graphs for monitoring positive surgical margin (PSM) rates during a surgeon's transition from open to robot-assisted radical prostatectomy (RARP)...
  20. ncbi request reprint Perineural invasion and TRUS findings are complementary in predicting prostate cancer biology
    Carlos H Martinez
    Department of Surgery, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada
    Can J Urol 20:6696-701. 2013
    ..We evaluated the combination of transrectal ultrasound-guided biopsy of the prostate (TRUSBx) pathologic and radiologic findings in their ability to predict the biologic potential of each prostate cancer...
  21. pmc Development and validation of a virtual reality transrectal ultrasound guided prostatic biopsy simulator
    Venu Chalasani
    Departments of Surgery and Oncology, Divisions of Urology and Surgical Oncology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON
    Can Urol Assoc J 5:19-26. 2011
    ..We present the design, reliability, face, content and construct validity testing of a virtual reality simulator for transrectal ultrasound (TRUS), which allows doctors-in-training to perform multiple different biopsy schemes...
  22. ncbi request reprint Metastatic Merkel cell tumor to the prostate and bladder
    Douglas P Mack
    Department of Surgery, Division of Urology, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada
    Urology 64:156-8. 2004
    ..Efforts should be made to optimize the patient's quality of life with the finding of metastatic Merkel cell carcinoma to the bladder or prostate until better adjuvant therapies are identified...
  23. pmc Total pelvic exenteration for rectal cancer: outcomes and prognostic factors
    Trustin S Domes
    Division of Urology, Department of Medicine, Schulich School of Medicine, University of Western Ontario, London, Ontario
    Can J Surg 54:387-93. 2011
    ..To perform complete resection of locally advanced and recurrent rectal carcinoma, total pelvic exenteration (TPE) may be attempted. We identified disease-related outcomes and prognostic factors...
  24. doi request reprint Quality assurance and benchmarking for radical cystectomy: monitoring early complications and mortality using cumulative summation charts
    Venu Chalasani
    Departments of Surgery and Oncology, Divisions of Urology and Surgical Oncology, Schulich School of Medicine and Dentistry, London, Ontario, Canada
    J Urol 181:1581-6. 2009
    ..In this study we used cumulative summation charts for quality assurance in radical cystectomies...
  25. doi request reprint Salvage radiotherapy following radical prostatectomy
    Venu Chalasani
    Departments of Surgery and Oncology, Divisions of Urology and Surgical Oncology, The Schulich School of Medicine and Dentistry, University of Western Ontario, Ontario, Canada
    Int J Urol 16:31-6. 2009
    ..Salvage radiotherapy can provide a durable response when given early, and patients with recurrent disease should be considered for treatment or enrolment in clinical trials...
  26. ncbi request reprint Timing cystectomy and perioperative chemotherapy in the treatment of muscle invasive bladder cancer
    Jonathan I Izawa
    Department of Surgery, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada
    Can J Urol 13:48-53. 2006
    ..Based on this data, we suggest optimal and feasible strategies for treating TCC in a resource-constrained environment...
  27. ncbi request reprint Treatment of radiation failure in prostate cancer
    Joseph L Chin
    University of Western Ontario, London, Ontario, Canada
    Can J Urol 13:48-51. 2006
    ..Management of patients who have failed of local radiotherapy remains a challenge. Herein the current therapeutic options are reviewed...
  28. ncbi request reprint Plasma osteopontin levels are predictive of disease stage in patients with transitional cell carcinoma of the bladder
    Celina Ang
    Department of Surgery, University of Western Ontario, London, Ontario, Canada
    BJU Int 96:803-5. 2005
    ..To measure plasma levels of osteopontin in patients with transitional cell carcinoma (TCC) of the bladder, and to determine if osteopontin levels relate to disease stage...
  29. ncbi request reprint Laparoscopic versus open partial nephrectomy
    Kenneth A Beasley
    Division of Urology, University of Western Ontario, London, Ontario, Canada
    Urology 64:458-61. 2004
    ..Limited data are available comparing LPN to OPN in the treatment of small renal tumors...
  30. ncbi request reprint Characterization of initiation of angiogenesis in early stages of prostate adenocarcinoma development and progression in a transgenic murine model
    Manal Gabril
    Department of Surgery, London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada
    Urology 64:1233-7. 2004
    ....
  31. ncbi request reprint Current status of local salvage therapies following radiation failure for prostate cancer
    Naji J Touma
    Division of Urology, University of Western Ontario, London, Ontario, Canada
    J Urol 173:373-9. 2005
    ..We reviewed the curative options available to patients with local failure after radical radiotherapy for prostate cancer and identified the patients best suited for such salvage therapies...
  32. ncbi request reprint Malignant neoplasm of perivascular epithelioid cells of the liver
    Jeremy R Parfitt
    Departments of Pathology, London Health Sciences Centre and University of Western Ontario, London, Ontario, Canada
    Arch Pathol Lab Med 130:1219-22. 2006
    ....
  33. ncbi request reprint The prognostic significance of metastatic perivesical lymph nodes identified in radical cystectomy specimens for transitional cell carcinoma of the bladder
    Anthony J Bella
    Department of Surgery, London Regional Cancer Centre, University of Western Ontario, London, Canada
    J Urol 170:2253-7. 2003
    ..We determined the prognostic significance of metastatic perivesical lymph nodes (PVLN) in transitional cell carcinoma of the bladder (TCC)...
  34. pmc Radical cystectomy for the treatment of T1 bladder cancer: the Canadian Bladder Cancer Network experience
    Venu Chalasani
    Departments of Surgery and Oncology, Divisions of Urology and Surgical Oncology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON
    Can Urol Assoc J 5:83-7. 2011
    ..We present our data from a large, multi-institutional, contemporary Canadian series of patients who underwent radical cystectomy for clinical T1 bladder cancer in a single-payer health care system...
  35. pmc Bladder perforation after immediate postoperative intravesical instillation of mitomycin C
    Darwin Lim
    Departments of Surgery and Oncology, Divisions of Urology and Surgical Oncology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON
    Can Urol Assoc J 4:E1-3. 2010
    ..We report our own experience of a male patient with bladder perforation after an early instillation of a single dose of MMC. In this case, systemic toxicity occurred which required intensive care after surgical repair...
  36. ncbi request reprint Histological changes in prostate biopsies after salvage cryotherapy: effect of chronology and the method of biopsy
    Jonathan I Izawa
    Department of Urology, The University of Texas, M D Anderson Center, Houston, TX 77030, USA
    BJU Int 98:554-8. 2006
    ....
  37. ncbi request reprint Clinical presentation and outcome of high-grade urinary bladder leiomyosarcoma in adults
    Charles J Rosser
    Department of Urology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Urology 61:1151-5. 2003
    ..To determine the clinical presentation and outcome of patients with high-grade bladder leiomyosarcoma...
  38. ncbi request reprint Incomplete glandular ablation after salvage cryotherapy for recurrent prostate cancer after radiotherapy
    Jonathan I Izawa
    Department of Urology, The University of Texas M D Anderson Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 56:468-72. 2003
    ..To determine the clinical variables associated with inadequate salvage cryotherapy and to correlate the disease-free survival rates associated with biopsy results in prostate cancer (CaP)...
  39. ncbi request reprint Salvage cryotherapy for recurrent prostate cancer after radiotherapy: variables affecting patient outcome
    Jonathan I Izawa
    Department of Urology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 20:2664-71. 2002
    ....
  40. ncbi request reprint Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude mice
    Takashi Karashima
    Department of Cancer Biology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Clin Cancer Res 8:1253-64. 2002
    ..The simultaneous administration of paclitaxel enhanced this effect...