S M Innis

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. ncbi request reprint Neonatal polyunsaturated fatty acid metabolism
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    Lipids 34:139-49. 1999
  2. ncbi request reprint trans Fatty acids in human milk are inversely associated with concentrations of essential all-cis n-6 and n-3 fatty acids and determine trans, but not n-6 and n-3, fatty acids in plasma lipids of breast-fed infants
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    Am J Clin Nutr 70:383-90. 1999
  3. ncbi request reprint Essential fatty acids in infant nutrition: lessons and limitations from animal studies in relation to studies on infant fatty acid requirements
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    Am J Clin Nutr 71:238S-44S. 2000
  4. ncbi request reprint The role of dietary n-6 and n-3 fatty acids in the developing brain
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, B C, Canada
    Dev Neurosci 22:474-80. 2000
  5. doi request reprint Low linoleic acid may facilitate Δ6 desaturase activity and docosahexaenoic acid accretion in human fetal development
    E M Novak
    Nutrition and Metabolism Research Program, Child and Family Research Institute, Department of Paediatrics, University of British Columbia, 950 West 28th Ave, Vancouver, B C, Canada V5Z 4H4
    Prostaglandins Leukot Essent Fatty Acids 86:93-8. 2012
  6. ncbi request reprint Dietary fatty acid composition in pregnancy alters neurite membrane fatty acids and dopamine in newborn rat brain
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada V5Z 4H4
    J Nutr 131:118-22. 2001
  7. ncbi request reprint Infant plasma trans, n-6, and n-3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and length
    S L Elias
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    Am J Clin Nutr 73:807-14. 2001
  8. ncbi request reprint Feeding formula without arachidonic acid and docosahexaenoic acid has no effect on preferential looking acuity or recognition memory in healthy full-term infants at 9 mo of age
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    Am J Clin Nutr 64:40-6. 1996
  9. pmc Antioxidant capacity of human milk and its association with vitamins A and E and fatty acid composition
    A Tijerina-Sáenz
    Food, Nutrition and Health, University of British Columbia, Vancouver, BC, Canada
    Acta Paediatr 98:1793-8. 2009
  10. ncbi request reprint Are human milk long-chain polyunsaturated fatty acids related to visual and neural development in breast-fed term infants?
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    J Pediatr 139:532-8. 2001

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Neonatal polyunsaturated fatty acid metabolism
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    Lipids 34:139-49. 1999
    ....
  2. ncbi request reprint trans Fatty acids in human milk are inversely associated with concentrations of essential all-cis n-6 and n-3 fatty acids and determine trans, but not n-6 and n-3, fatty acids in plasma lipids of breast-fed infants
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    Am J Clin Nutr 70:383-90. 1999
    ..The effects of milk trans, n-6, and n-3 fatty acids in breast-fed infants are unclear, although n-6 and n-3 fatty acids are important in infant growth and development...
  3. ncbi request reprint Essential fatty acids in infant nutrition: lessons and limitations from animal studies in relation to studies on infant fatty acid requirements
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    Am J Clin Nutr 71:238S-44S. 2000
    ..Animal studies can provide important information on the mechanisms of both beneficial and adverse effects and the pathways of brain 22:6n-3 uptake...
  4. ncbi request reprint The role of dietary n-6 and n-3 fatty acids in the developing brain
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, B C, Canada
    Dev Neurosci 22:474-80. 2000
    ..These findings should guide clinical studies to more sensitive measures of the functional roles of dietary n-3 fatty acids and to clinical conditions where n-3 fatty acids may have benefit...
  5. doi request reprint Low linoleic acid may facilitate Δ6 desaturase activity and docosahexaenoic acid accretion in human fetal development
    E M Novak
    Nutrition and Metabolism Research Program, Child and Family Research Institute, Department of Paediatrics, University of British Columbia, 950 West 28th Ave, Vancouver, B C, Canada V5Z 4H4
    Prostaglandins Leukot Essent Fatty Acids 86:93-8. 2012
    ..These findings suggest low placental transfer of 18:2n-6 may be a specific mechanism to prevent inhibition of fetal Δ6 desaturase and facilitate fetal cellular phospholipid 22:6n-3 accretion...
  6. ncbi request reprint Dietary fatty acid composition in pregnancy alters neurite membrane fatty acids and dopamine in newborn rat brain
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada V5Z 4H4
    J Nutr 131:118-22. 2001
    ..The functional importance, however, is not known at this time...
  7. ncbi request reprint Infant plasma trans, n-6, and n-3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and length
    S L Elias
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    Am J Clin Nutr 73:807-14. 2001
    ..33) and between TFA and AA concentrations in cholesteryl esters (r = -0.23). CONCLUSION: The results suggest possible important effects of TFAs and of AA on fetal growth and length of gestation...
  8. ncbi request reprint Feeding formula without arachidonic acid and docosahexaenoic acid has no effect on preferential looking acuity or recognition memory in healthy full-term infants at 9 mo of age
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    Am J Clin Nutr 64:40-6. 1996
    ....
  9. pmc Antioxidant capacity of human milk and its association with vitamins A and E and fatty acid composition
    A Tijerina-Sáenz
    Food, Nutrition and Health, University of British Columbia, Vancouver, BC, Canada
    Acta Paediatr 98:1793-8. 2009
    ..The aim of this study was to use the Oxygen Radical Absorbance Capacity assay to assess human milk antioxidant capacity and find correlations with milk components...
  10. ncbi request reprint Are human milk long-chain polyunsaturated fatty acids related to visual and neural development in breast-fed term infants?
    S M Innis
    Department of Paediatrics, University of British Columbia, Vancouver, Canada
    J Pediatr 139:532-8. 2001
    ..To determine whether docosahexaenoic acid (DHA) is related to visual and neural development in term breast-fed infants...
  11. doi request reprint Long chain omega-3 fatty acids: micronutrients in disguise
    S M Innis
    Department of Paediatrics, Nutrition and Metabolism Research Program, Child and Family Research Institute, Vancouver, BC, Canada V5Z 4H4
    Prostaglandins Leukot Essent Fatty Acids 88:91-5. 2013
    ....
  12. ncbi request reprint Cholesterol synthesis and accretion within various tissues of the fetal and neonatal rat
    N C Haave
    Department of Pathology, University of British Columbia, Vancouver, Canada
    Metabolism 50:12-8. 2001
    ..However, the fetal liver may support cholesterol accretion in other tissues through rates of synthesis in excess of accumulation and secretion into plasma. The placenta may derive some cholesterol from the maternal and/or fetal plasma...
  13. doi request reprint Dietary long chain n-3 fatty acids are more closely associated with protein than energy intakes from fat
    E M Novak
    Nutrition and Metabolism Research Program, Child and Family Research Institute, Department of Paediatrics, University of British Columbia, 950 West 28th Ave, Vancouver, B C, Canada V5Z 4H4
    Prostaglandins Leukot Essent Fatty Acids 86:107-12. 2012
    ..Recommendations regarding EPA and DHA intake should focus on protein sources, rather than diet fat, and consider their potential roles in amino acid and protein metabolism...
  14. ncbi request reprint Essential fatty acid transfer and fetal development
    S M Innis
    Department of Paediatrics, Nutrition Research Program, University of British Columbia, B C Research Institute for Maternal and Child Health, Room 179, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada
    Placenta 26:S70-5. 2005
    ..Consideration needs to be given to whether fetal plasma 22:6n-3 and 20:4n-6 enrichment and the low 18:2n-6 facilitates accretion of 22:6n-3 and 20:4n-6 in developing tissues...
  15. ncbi request reprint Metformin influences cardiomyocyte cell death by pathways that are dependent and independent of caspase-3
    D An
    Division of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, The University of British Columbia, 2146 East Mall, Vancouver, BC, Canada, V6T 1Z3
    Diabetologia 49:2174-84. 2006
    ..Metformin has been shown to increase fatty acid oxidation, an effect mediated by AMP activated protein kinase (AMPK). We hypothesised that metformin could prevent both caspase-3 activation and apoptosis when induced by palmitic acid...
  16. doi request reprint Maternal vitamin D status in pregnancy and adverse pregnancy outcomes in a group at high risk for pre-eclampsia
    A W Shand
    Department of Maternal Fetal Medicine, BC Women s Hospital, Vancouver, BC, Canada
    BJOG 117:1593-8. 2010
    ..To determine in a group of pregnant women if vitamin D status, based on serum 25-hydroxyvitamin D (25OHD) concentration, was associated with a subsequent risk of pre-eclampsia or adverse pregnancy outcomes...