Janine R Hutson

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. doi request reprint Use of clarithromycin and adverse cardiovascular events among older patients receiving donepezil: a population-based, nested case-control study
    Janine R Hutson
    Faculty of Medicine, University of Toronto, Toronto, ON, Canada
    Drugs Aging 29:205-11. 2012
  2. ncbi request reprint Prediction of placental drug transfer using the human placental perfusion model
    Janine R Hutson
    Collaborative Program in Biomedical Toxicology, University of Toronto, Canada
    J Popul Ther Clin Pharmacol 18:e533-43. 2011
  3. doi request reprint False-positive meconium test results for fatty acid ethyl esters secondary to delayed sample collection
    Irene Zelner
    Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Alcohol Clin Exp Res 36:1497-506. 2012
  4. pmc Toxico-surveillance of infant and toddler poisonings in the United States
    Yaron Finkelstein
    Division of Emergency Medicine, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    J Med Toxicol 8:263-6. 2012
  5. doi request reprint Pharmacokinetic and pharmacogenetic determinants and considerations in chemotherapy selection and dosing in infants
    Janine R Hutson
    University of Toronto, Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, 555 University Ave, Toronto ON, M5G 1X8, Canada
    Expert Opin Drug Metab Toxicol 8:709-22. 2012
  6. doi request reprint Colchicine poisoning: the dark side of an ancient drug
    Yaron Finkelstein
    Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    Clin Toxicol (Phila) 48:407-14. 2010
  7. doi request reprint Methadone: a review of drug-drug and pathophysiological interactions
    Bhushan M Kapur
    Department of Clinical Pathology, Sunnybrook Health Sciences Centre, Toronto, Canada
    Crit Rev Clin Lab Sci 48:171-95. 2011
  8. doi request reprint Genetic polymorphisms in placental transporters: implications for fetal drug exposure to oral antidiabetic agents
    Erika K Pollex
    Hospital for Sick Children, Motherisk Laboratory, 555 University Ave, Toronto, Ontario M5G 1X8, Canada
    Expert Opin Drug Metab Toxicol 7:325-39. 2011
  9. doi request reprint An improved method for rapidly quantifying fatty acid ethyl esters in meconium suitable for prenatal alcohol screening
    Janine R Hutson
    Motherisk Laboratory, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
    Alcohol 45:193-9. 2011
  10. pmc Folic acid transport to the human fetus is decreased in pregnancies with chronic alcohol exposure
    Janine R Hutson
    Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada
    PLoS ONE 7:e38057. 2012

Detail Information

Publications10

  1. doi request reprint Use of clarithromycin and adverse cardiovascular events among older patients receiving donepezil: a population-based, nested case-control study
    Janine R Hutson
    Faculty of Medicine, University of Toronto, Toronto, ON, Canada
    Drugs Aging 29:205-11. 2012
    ..Donepezil is metabolized by the cytochrome P450 isozyme 3A4 (CYP3A4). Clarithromycin is a potent inhibitor of CYP3A4, and patients taking both of these drugs may be at increased risk of cardiac adverse events...
  2. ncbi request reprint Prediction of placental drug transfer using the human placental perfusion model
    Janine R Hutson
    Collaborative Program in Biomedical Toxicology, University of Toronto, Canada
    J Popul Ther Clin Pharmacol 18:e533-43. 2011
    ..After modelling the data, placental perfusion experiments can be used to predict placental drug transfer and can be useful for clinical assessment of the risks and benefits of drug therapy in pregnancy...
  3. doi request reprint False-positive meconium test results for fatty acid ethyl esters secondary to delayed sample collection
    Irene Zelner
    Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Alcohol Clin Exp Res 36:1497-506. 2012
    ..This study investigated whether delayed sample collection can result in false-positive test results for FAEEs because of collection of samples potentially contaminated with postnatally produced stool...
  4. pmc Toxico-surveillance of infant and toddler poisonings in the United States
    Yaron Finkelstein
    Division of Emergency Medicine, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    J Med Toxicol 8:263-6. 2012
    ..These data could be used to target specific preventive interventions...
  5. doi request reprint Pharmacokinetic and pharmacogenetic determinants and considerations in chemotherapy selection and dosing in infants
    Janine R Hutson
    University of Toronto, Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, 555 University Ave, Toronto ON, M5G 1X8, Canada
    Expert Opin Drug Metab Toxicol 8:709-22. 2012
    ....
  6. doi request reprint Colchicine poisoning: the dark side of an ancient drug
    Yaron Finkelstein
    Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    Clin Toxicol (Phila) 48:407-14. 2010
    ..Although colchicine poisoning is sometimes intentional, unintentional toxicity is common and often associated with a poor outcome...
  7. doi request reprint Methadone: a review of drug-drug and pathophysiological interactions
    Bhushan M Kapur
    Department of Clinical Pathology, Sunnybrook Health Sciences Centre, Toronto, Canada
    Crit Rev Clin Lab Sci 48:171-95. 2011
    ....
  8. doi request reprint Genetic polymorphisms in placental transporters: implications for fetal drug exposure to oral antidiabetic agents
    Erika K Pollex
    Hospital for Sick Children, Motherisk Laboratory, 555 University Ave, Toronto, Ontario M5G 1X8, Canada
    Expert Opin Drug Metab Toxicol 7:325-39. 2011
    ..Further research employing in vivo models is required to allow for the prediction of the potential consequences of polymorphisms on placental transporter expression and function...
  9. doi request reprint An improved method for rapidly quantifying fatty acid ethyl esters in meconium suitable for prenatal alcohol screening
    Janine R Hutson
    Motherisk Laboratory, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
    Alcohol 45:193-9. 2011
    ..This method provides an optimal approach to detecting and quantifying FAEE in meconium that could be used in a universal screening program for prenatal alcohol exposure...
  10. pmc Folic acid transport to the human fetus is decreased in pregnancies with chronic alcohol exposure
    Janine R Hutson
    Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada
    PLoS ONE 7:e38057. 2012
    ..We aim to determine if folate transfer to the fetus is altered in human pregnancies with chronic alcohol consumption...