Research Topics
| J B HudsonSummaryAffiliation: University of British Columbia Country: Canada Publications
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Detail Information
Publications
The antimicrobial properties of cedar leaf (Thuja plicata) oil; a safe and efficient decontamination agent for buildingsJames Hudson
Department of Pathology and Laboratory Medicine, University of British Columbia, 2733 Heather Street, Vancouver, BC V5Z 3J5, Canada
Int J Environ Res Public Health 8:4477-87. 2011..Based on these results, CLO shows promise as a prospective safe, green, broad-spectrum anti-microbial agent for decontamination of buildings...- Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV)Stephan Pleschka
Institute for Medical Virology, Justus Liebig University Giessen, Giessen, Germany
Virol J 6:197. 2009..As an alternative approach to the common anti-virals we studied in more detail a commercial standardized extract of the widely used herb Echinacea purpurea (Echinaforce, EF) in order to elucidate the nature of its anti-IV activity... 
Bromohypericins are potent photoactive antiviral agentsJ B Hudson
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
Photochem Photobiol 70:820-2. 1999....- Inactivation of Norovirus by ozone gas in conditions relevant to healthcareJ B Hudson
Viroforce Systems Inc Laboratory, Vancouver, Canada
J Hosp Infect 66:40-5. 2007..Our results show that Norovirus can be inactivated by exposure to ozone gas from a portable commercial generator in settings such as hotel rooms, cruise ship cabins and healthcare facilities... - The application of DNA micro-arrays (gene arrays) to the study of herbal medicinesJim Hudson
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada V5Z 1M9
J Ethnopharmacol 108:2-15. 2006.... - Applications of the phytomedicine Echinacea purpurea (Purple Coneflower) in infectious diseasesJames B Hudson
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada V5Z 3J5
J Biomed Biotechnol 2012:769896. 2012..Potential applications of the bioactive extracts may go beyond their traditional uses... 
Bactericidal and anti-inflammatory properties of a standardized Echinacea extract (Echinaforce): dual actions against respiratory bacteriaS M Sharma
Department of Pathology and Laboratory Medicine, University of British Columbia, 2733 Heather Street, Vancouver, BC, Canada
Phytomedicine 17:563-8. 2010..These results support the concept of using a standardized Echinacea preparation to control symptoms associated with bacterial respiratory infections...- The efficacy of Echinacea in a 3-D tissue model of human airway epitheliumM Sharma
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada
Phytother Res 24:900-4. 2010..These results confirmed previous findings derived from studies of bronchial and lung epithelial cell lines, namely, that RV infection results in a substantial inflammatory response in the absence of virus replication... - Echinacea extracts modulate the production of multiple transcription factors in uninfected cells and rhinovirus-infected cellsM Sharma
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
Phytother Res 20:1074-9. 2006..In addition, the results could help to explain the beneficial effects of Echinacea consumption... - Echinacea as an antiinflammatory agent: the influence of physiologically relevant parametersM Sharma
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
Phytother Res 23:863-7. 2009..It is concluded that under real life conditions of Echinacea consumption, the virus-induced stimulation of pro-inflammatory cytokines can be effectively reversed or alleviated... - Antiviral and antimicrobial activities of Colombian medicinal plantsA Lopez
Department of Botany, University of British Columbia, University Campus, 3529-6270 University Boulevard, Vancouver BC, V6T 1Z4, Canada
J Ethnopharmacol 77:189-96. 2001..We concluded that these Colombian medicinal plants represent an untapped source of potentially useful antivirals and are worthy of further study... - The potential use of Echinacea in acne: control of Propionibacterium acnes growth and inflammationM Sharma
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
Phytother Res 25:517-21. 2011..Thus Echinaforce® could provide a safe two-fold benefit to acne individuals by inhibiting proliferation of the organism and reversing the bacterial-induced inflammation... - Modulation of immune response gene expression by echinacea extracts: results of a gene array analysisM Altamirano Dimas
Department of Pathology and Laboratory Medicine, University of British Columbia, C 360 Heather Pavilion, Vancouver, BC V5Z 1M9, Canada
Can J Physiol Pharmacol 85:1091-8. 2007..This suggests that Echinacea can bring about important biological responses in cells by virtue of interactions between components of the extract and a small number of intracellular factors involved in multiple signaling pathways... - Antiviral activities of photoactive perylenequinonesJ B Hudson
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
Photochem Photobiol 65:352-4. 1997..Thus, for some groups of PQ there was correlation between quantum yield of singlet oxygen (1O2) and antiviral efficacy, but there are evidently other structural features of PQ that influence activity... - Echinacea extracts modulate the pattern of chemokine and cytokine secretion in rhinovirus-infected and uninfected epithelial cellsM Sharma
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
Phytother Res 20:147-52. 2006..Furthermore, a number of these cytokines were stimulated by the same Echinacea preparations in uninfected cells. These observations therefore provide support for the alleged beneficial uses of Echinacea extracts... - Tumor-specific and photodependent cytotoxicity of hypericin in the human LNCaP prostate tumor modelX Xie
Department of Surgery, Prostate Centre at Vancouver General Hospital, University of British Columbia, Vancouver, Canada
Photochem Photobiol 74:221-5. 2001..Although the results reported for the current studies are preliminary they do provide evidence for an application of HYP PDT to prostate cancer which warrants further investigation... - Plant photosensitizers with antiviral propertiesJ B Hudson
Division of Medical Microbiology, University of British Columbia, Vancouver, Canada
Antiviral Res 12:55-74. 1989..Some of these compounds have potent antiviral activities at concentrations well below cytotoxic levels, and accordingly should be tested in animal models... - The efficacy of amantadine and other antiviral compounds against two salmonid viruses in vitroJ B Hudson
Division of Medical Microbiology, University of British Columbia, Vancouver, Canada
Antiviral Res 9:379-85. 1988..Several other compounds were also tested but they were not inhibitory to either virus. The attraction of amantadine is the fact that relatively easy administration should be feasible... - Ethnomedicinal uses of Momordicacharantia (Cucurbitaceae) in Togo and relation to its phytochemistry and biological activityNadine Beloin
Biology Department, University of Ottawa, Ottawa, Ont, Canada K1N 6N5
J Ethnopharmacol 96:49-55. 2005..However, momordicins were found to be anthelmintic but not antiviral. Traditional healers collected plants in dry areas where momordicin content is greater...