J B Hudson

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. pmc The antimicrobial properties of cedar leaf (Thuja plicata) oil; a safe and efficient decontamination agent for buildings
    James Hudson
    Department of Pathology and Laboratory Medicine, University of British Columbia, 2733 Heather Street, Vancouver, BC V5Z 3J5, Canada
    Int J Environ Res Public Health 8:4477-87. 2011
  2. pmc Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV)
    Stephan Pleschka
    Institute for Medical Virology, Justus Liebig University Giessen, Giessen, Germany
    Virol J 6:197. 2009
  3. ncbi request reprint Inactivation of Norovirus by ozone gas in conditions relevant to healthcare
    J B Hudson
    Viroforce Systems Inc Laboratory, Vancouver, Canada
    J Hosp Infect 66:40-5. 2007
  4. ncbi request reprint Bromohypericins are potent photoactive antiviral agents
    J B Hudson
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Photochem Photobiol 70:820-2. 1999
  5. ncbi request reprint The application of DNA micro-arrays (gene arrays) to the study of herbal medicines
    Jim Hudson
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada V5Z 1M9
    J Ethnopharmacol 108:2-15. 2006
  6. pmc Applications of the phytomedicine Echinacea purpurea (Purple Coneflower) in infectious diseases
    James B Hudson
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada V5Z 3J5
    J Biomed Biotechnol 2012:769896. 2012
  7. doi request reprint Bactericidal and anti-inflammatory properties of a standardized Echinacea extract (Echinaforce): dual actions against respiratory bacteria
    S M Sharma
    Department of Pathology and Laboratory Medicine, University of British Columbia, 2733 Heather Street, Vancouver, BC, Canada
    Phytomedicine 17:563-8. 2010
  8. doi request reprint The efficacy of Echinacea in a 3-D tissue model of human airway epithelium
    M Sharma
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada
    Phytother Res 24:900-4. 2010
  9. ncbi request reprint Echinacea extracts modulate the production of multiple transcription factors in uninfected cells and rhinovirus-infected cells
    M Sharma
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Phytother Res 20:1074-9. 2006
  10. doi request reprint Echinacea as an antiinflammatory agent: the influence of physiologically relevant parameters
    M Sharma
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Phytother Res 23:863-7. 2009

Collaborators

  • M Sharma
  • R Schoop
  • J T Arnason
  • S M Sharma
  • Stephan Pleschka
  • M Altamirano-Dimas
  • Nadine Beloin
  • S A Anderson
  • C C Collins
  • M E Cox
  • C Levenson
  • R H Bell
  • A Lopez
  • X Xie
  • A Suter
  • M Anderson
  • S R Schoop
  • Roland Schoop
  • Michael Stein
  • C Nelson
  • D Cochrane
  • A Burt
  • Kossi Koumaglo
  • Komlan de Soussa
  • J Thor Arnason
  • Messanvi Gbeassor
  • Koffi Akpagana
  • E S Guns
  • G H Towers

Detail Information

Publications20

  1. pmc The antimicrobial properties of cedar leaf (Thuja plicata) oil; a safe and efficient decontamination agent for buildings
    James Hudson
    Department of Pathology and Laboratory Medicine, University of British Columbia, 2733 Heather Street, Vancouver, BC V5Z 3J5, Canada
    Int J Environ Res Public Health 8:4477-87. 2011
    ..Based on these results, CLO shows promise as a prospective safe, green, broad-spectrum anti-microbial agent for decontamination of buildings...
  2. pmc Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV)
    Stephan Pleschka
    Institute for Medical Virology, Justus Liebig University Giessen, Giessen, Germany
    Virol J 6:197. 2009
    ..As an alternative approach to the common anti-virals we studied in more detail a commercial standardized extract of the widely used herb Echinacea purpurea (Echinaforce, EF) in order to elucidate the nature of its anti-IV activity...
  3. ncbi request reprint Inactivation of Norovirus by ozone gas in conditions relevant to healthcare
    J B Hudson
    Viroforce Systems Inc Laboratory, Vancouver, Canada
    J Hosp Infect 66:40-5. 2007
    ..Our results show that Norovirus can be inactivated by exposure to ozone gas from a portable commercial generator in settings such as hotel rooms, cruise ship cabins and healthcare facilities...
  4. ncbi request reprint Bromohypericins are potent photoactive antiviral agents
    J B Hudson
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Photochem Photobiol 70:820-2. 1999
    ....
  5. ncbi request reprint The application of DNA micro-arrays (gene arrays) to the study of herbal medicines
    Jim Hudson
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada V5Z 1M9
    J Ethnopharmacol 108:2-15. 2006
    ....
  6. pmc Applications of the phytomedicine Echinacea purpurea (Purple Coneflower) in infectious diseases
    James B Hudson
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada V5Z 3J5
    J Biomed Biotechnol 2012:769896. 2012
    ..Potential applications of the bioactive extracts may go beyond their traditional uses...
  7. doi request reprint Bactericidal and anti-inflammatory properties of a standardized Echinacea extract (Echinaforce): dual actions against respiratory bacteria
    S M Sharma
    Department of Pathology and Laboratory Medicine, University of British Columbia, 2733 Heather Street, Vancouver, BC, Canada
    Phytomedicine 17:563-8. 2010
    ..These results support the concept of using a standardized Echinacea preparation to control symptoms associated with bacterial respiratory infections...
  8. doi request reprint The efficacy of Echinacea in a 3-D tissue model of human airway epithelium
    M Sharma
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada
    Phytother Res 24:900-4. 2010
    ..These results confirmed previous findings derived from studies of bronchial and lung epithelial cell lines, namely, that RV infection results in a substantial inflammatory response in the absence of virus replication...
  9. ncbi request reprint Echinacea extracts modulate the production of multiple transcription factors in uninfected cells and rhinovirus-infected cells
    M Sharma
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Phytother Res 20:1074-9. 2006
    ..In addition, the results could help to explain the beneficial effects of Echinacea consumption...
  10. doi request reprint Echinacea as an antiinflammatory agent: the influence of physiologically relevant parameters
    M Sharma
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Phytother Res 23:863-7. 2009
    ..It is concluded that under real life conditions of Echinacea consumption, the virus-induced stimulation of pro-inflammatory cytokines can be effectively reversed or alleviated...
  11. ncbi request reprint Antiviral and antimicrobial activities of Colombian medicinal plants
    A Lopez
    Department of Botany, University of British Columbia, University Campus, 3529-6270 University Boulevard, Vancouver BC, V6T 1Z4, Canada
    J Ethnopharmacol 77:189-96. 2001
    ..We concluded that these Colombian medicinal plants represent an untapped source of potentially useful antivirals and are worthy of further study...
  12. doi request reprint The potential use of Echinacea in acne: control of Propionibacterium acnes growth and inflammation
    M Sharma
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Phytother Res 25:517-21. 2011
    ..Thus Echinaforce® could provide a safe two-fold benefit to acne individuals by inhibiting proliferation of the organism and reversing the bacterial-induced inflammation...
  13. ncbi request reprint Modulation of immune response gene expression by echinacea extracts: results of a gene array analysis
    M Altamirano-Dimas
    Department of Pathology and Laboratory Medicine, University of British Columbia, C 360 Heather Pavilion, Vancouver, BC V5Z 1M9, Canada
    Can J Physiol Pharmacol 85:1091-8. 2007
    ..This suggests that Echinacea can bring about important biological responses in cells by virtue of interactions between components of the extract and a small number of intracellular factors involved in multiple signaling pathways...
  14. ncbi request reprint Antiviral activities of photoactive perylenequinones
    J B Hudson
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Photochem Photobiol 65:352-4. 1997
    ..Thus, for some groups of PQ there was correlation between quantum yield of singlet oxygen (1O2) and antiviral efficacy, but there are evidently other structural features of PQ that influence activity...
  15. ncbi request reprint Echinacea extracts modulate the pattern of chemokine and cytokine secretion in rhinovirus-infected and uninfected epithelial cells
    M Sharma
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Phytother Res 20:147-52. 2006
    ..Furthermore, a number of these cytokines were stimulated by the same Echinacea preparations in uninfected cells. These observations therefore provide support for the alleged beneficial uses of Echinacea extracts...
  16. ncbi request reprint Plant photosensitizers with antiviral properties
    J B Hudson
    Division of Medical Microbiology, University of British Columbia, Vancouver, Canada
    Antiviral Res 12:55-74. 1989
    ..Some of these compounds have potent antiviral activities at concentrations well below cytotoxic levels, and accordingly should be tested in animal models...
  17. ncbi request reprint Tumor-specific and photodependent cytotoxicity of hypericin in the human LNCaP prostate tumor model
    X Xie
    Department of Surgery, Prostate Centre at Vancouver General Hospital, University of British Columbia, Vancouver, Canada
    Photochem Photobiol 74:221-5. 2001
    ..Although the results reported for the current studies are preliminary they do provide evidence for an application of HYP PDT to prostate cancer which warrants further investigation...
  18. ncbi request reprint Suppression of Lipopolysaccharide-stimulated Cytokine/Chemokine Production in Skin Cells by Sandalwood Oils and Purified α-santalol and β-santalol
    M Sharma
    The Vancouver Prostate Centre, Vancouver General Hospital, Vancouver, BC, V6H3Z6, Canada
    Phytother Res 28:925-32. 2014
    ..Copyright © 2013 John Wiley & Sons, Ltd. ..
  19. ncbi request reprint The efficacy of amantadine and other antiviral compounds against two salmonid viruses in vitro
    J B Hudson
    Division of Medical Microbiology, University of British Columbia, Vancouver, Canada
    Antiviral Res 9:379-85. 1988
    ..Several other compounds were also tested but they were not inhibitory to either virus. The attraction of amantadine is the fact that relatively easy administration should be feasible...
  20. ncbi request reprint Ethnomedicinal uses of Momordicacharantia (Cucurbitaceae) in Togo and relation to its phytochemistry and biological activity
    Nadine Beloin
    Biology Department, University of Ottawa, Ottawa, Ont, Canada K1N 6N5
    J Ethnopharmacol 96:49-55. 2005
    ..However, momordicins were found to be anthelmintic but not antiviral. Traditional healers collected plants in dry areas where momordicin content is greater...