D Houle

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. pmc Comparing mutational variabilities
    D Houle
    Department of Zoology, University of Toronto, Ontario, Canada
    Genetics 143:1467-83. 1996
  2. ncbi request reprint The effect of cryopreservation on the lethal mutation rate in Drosophila melanogaster
    D Houle
    Department of Zoology, University of Toronto, Ontario, Canada
    Genet Res 69:209-13. 1997
  3. ncbi request reprint The effects of spontaneous mutation on quantitative traits. II. Dominance of mutations with effects on life-history traits
    D Houle
    Department of Ecology and Evolution, University of Chicago, IL 60637 1573, USA
    Genet Res 70:27-34. 1997
  4. ncbi request reprint How should we explain variation in the genetic variance of traits?
    D Houle
    Department of Zoology, University of Toronto, Ontario, Canada
    Genetica 102:241-53. 1998

Detail Information

Publications4

  1. pmc Comparing mutational variabilities
    D Houle
    Department of Zoology, University of Toronto, Ontario, Canada
    Genetics 143:1467-83. 1996
    ..VC/VM averages about 50 generations for life history traits and 100 generations for morphological traits. These observations are all consistent with the predictions of a mutation-selection balance model...
  2. ncbi request reprint The effect of cryopreservation on the lethal mutation rate in Drosophila melanogaster
    D Houle
    Department of Zoology, University of Toronto, Ontario, Canada
    Genet Res 69:209-13. 1997
    ..39. This is the first quantitative estimate of the mutagenic effect of cryopreservation on the germ line of a metazoan. The results are reassuring when considering the genetic impact of cryopreservation on mammalian gametes and embryos...
  3. ncbi request reprint The effects of spontaneous mutation on quantitative traits. II. Dominance of mutations with effects on life-history traits
    D Houle
    Department of Ecology and Evolution, University of Chicago, IL 60637 1573, USA
    Genet Res 70:27-34. 1997
    ..These results are consistent with those of many other studies that suggest that both unselected mutations and those found segregating in natural populations are partially recessive...
  4. ncbi request reprint How should we explain variation in the genetic variance of traits?
    D Houle
    Department of Zoology, University of Toronto, Ontario, Canada
    Genetica 102:241-53. 1998
    ..Additional information concerning the pleiotropic consequences of mutations would help to validate the fitness sensitivities used to test the elimination and canalization hypotheses...