Mojgan Hodaie

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Involvement of the basal ganglia and cerebellar motor pathways in the preparation of self-initiated and externally triggered movements in humans
    Jamie Purzner
    The Krembil Neuroscience Centre and Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada M5T 2S8
    J Neurosci 27:6029-36. 2007
  2. ncbi request reprint Advances in the management of trigeminal neuralgia
    M Hodaie
    Division of Neurosurgery, Toronto Western Hospital and Department of Surgery, University of Toronto, Canada
    J Neurosurg Sci 57:13-21. 2013
  3. pmc Tractography delineates microstructural changes in the trigeminal nerve after focal radiosurgery for trigeminal neuralgia
    Mojgan Hodaie
    Division of Neurosurgery, Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada
    PLoS ONE 7:e32745. 2012
  4. doi request reprint In vivo visualization of cranial nerve pathways in humans using diffusion-based tractography
    Mojgan Hodaie
    Division of Neurosurgery, University of Toronto and Toronto Western Hospital, Toronto, Canada
    Neurosurgery 66:788-95; discussion 795-6. 2010
  5. ncbi request reprint The dopaminergic nigrostriatal system and Parkinson's disease: molecular events in development, disease, and cell death, and new therapeutic strategies
    Mojgan Hodaie
    Division of Neurosurgery, Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Canada
    Neurosurgery 60:17-28; discussion 28-30. 2007
  6. pmc Spinal cord stimulators and radiotherapy: first case report and practice guidelines
    Lorraine Walsh
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto M5G2M9, Ontario, Canada
    Radiat Oncol 6:143. 2011
  7. doi request reprint Modulation of Beta oscillations in the subthalamic nucleus with prosaccades and antisaccades in Parkinson's disease
    Akihiro Yugeta
    Division of Neurology, Toronto Western Research Institute, and the Edmond J Safra Program in Parkinson s Disease, University of Toronto, Toronto, Ontario M5T 2S8, Canada
    J Neurosci 33:6895-904. 2013
  8. doi request reprint Dopamine-dependent high-frequency oscillatory activity in thalamus and subthalamic nucleus of patients with Parkinson's disease
    Abdoul Kane
    Department of Physiology, University of Toronto, Toronto, Ontario, Canada
    Neuroreport 20:1549-53. 2009
  9. doi request reprint High-frequency microstimulation in human globus pallidus and substantia nigra
    Myriam Lafreniere-Roula
    Department of Physiology, University of Toronto, Medical Sciences Building Room 3302, 1 King s College Circle, Toronto, ON, M5S 1A8, Canada
    Exp Brain Res 205:251-61. 2010
  10. doi request reprint Pedunculopontine nucleus evoked potentials from subthalamic nucleus stimulation in Parkinson's disease
    Bogdan Neagu
    Toronto Western Research Institute, University Health Network, University of Toronto, Canada
    Exp Neurol 250:221-7. 2013

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Involvement of the basal ganglia and cerebellar motor pathways in the preparation of self-initiated and externally triggered movements in humans
    Jamie Purzner
    The Krembil Neuroscience Centre and Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada M5T 2S8
    J Neurosci 27:6029-36. 2007
    ..The CTC pathway is involved in the preparation of self-paced but not externally cued movements, although the pathway may still be involved in the execution of these movements...
  2. ncbi request reprint Advances in the management of trigeminal neuralgia
    M Hodaie
    Division of Neurosurgery, Toronto Western Hospital and Department of Surgery, University of Toronto, Canada
    J Neurosurg Sci 57:13-21. 2013
    ..The different options for surgical treatment, recent advances in each as well as novel methods of imaging of the trigeminal nerve focusing on diffusion tensor imaging/tractography will be discussed...
  3. pmc Tractography delineates microstructural changes in the trigeminal nerve after focal radiosurgery for trigeminal neuralgia
    Mojgan Hodaie
    Division of Neurosurgery, Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada
    PLoS ONE 7:e32745. 2012
    ..Changes in specific diffusivities may provide insight into the mechanism of action of radiosurgery on the trigeminal nerve...
  4. doi request reprint In vivo visualization of cranial nerve pathways in humans using diffusion-based tractography
    Mojgan Hodaie
    Division of Neurosurgery, University of Toronto and Toronto Western Hospital, Toronto, Canada
    Neurosurgery 66:788-95; discussion 795-6. 2010
    ..In particular, the feasibility of tractography of the individual cranial nerves has not been previously assessed...
  5. ncbi request reprint The dopaminergic nigrostriatal system and Parkinson's disease: molecular events in development, disease, and cell death, and new therapeutic strategies
    Mojgan Hodaie
    Division of Neurosurgery, Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Canada
    Neurosurgery 60:17-28; discussion 28-30. 2007
    ..These advancements are used as a template to review emerging therapeutic techniques, including neuroprotection strategies, surgical treatment of trophic factors, gene therapy, and neural transplantation...
  6. pmc Spinal cord stimulators and radiotherapy: first case report and practice guidelines
    Lorraine Walsh
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto M5G2M9, Ontario, Canada
    Radiat Oncol 6:143. 2011
    ..We also provide useful practical recommendations on the management of this scenario within a radiation oncology department...
  7. doi request reprint Modulation of Beta oscillations in the subthalamic nucleus with prosaccades and antisaccades in Parkinson's disease
    Akihiro Yugeta
    Division of Neurology, Toronto Western Research Institute, and the Edmond J Safra Program in Parkinson s Disease, University of Toronto, Toronto, Ontario M5T 2S8, Canada
    J Neurosci 33:6895-904. 2013
    ..Beta-band desynchronization in the STN may reflect the additional processes associated with suppression of reflexive responses and volitional execution of saccades in the opposite direction...
  8. doi request reprint Dopamine-dependent high-frequency oscillatory activity in thalamus and subthalamic nucleus of patients with Parkinson's disease
    Abdoul Kane
    Department of Physiology, University of Toronto, Toronto, Ontario, Canada
    Neuroreport 20:1549-53. 2009
    ..These findings confirm and extend earlier findings suggesting that in PD there are marked changes in basal ganglia oscillatory activity and that these can be reversed after dopaminergic therapy...
  9. doi request reprint High-frequency microstimulation in human globus pallidus and substantia nigra
    Myriam Lafreniere-Roula
    Department of Physiology, University of Toronto, Medical Sciences Building Room 3302, 1 King s College Circle, Toronto, ON, M5S 1A8, Canada
    Exp Brain Res 205:251-61. 2010
    ..The findings suggest that high-frequency microstimulation of the GPi and SNr depresses local neuronal activity and synaptic transmission, and such mechanisms may contribute to the therapeutic effects of DBS...
  10. doi request reprint Pedunculopontine nucleus evoked potentials from subthalamic nucleus stimulation in Parkinson's disease
    Bogdan Neagu
    Toronto Western Research Institute, University Health Network, University of Toronto, Canada
    Exp Neurol 250:221-7. 2013
    ..These results demonstrate a functional connection between the STN and the PPNR. It likely involves direct projections between the STN and PPNR or polysynaptic pathways with thalamic or cortical relays. ..
  11. doi request reprint Spatial extent of β oscillatory activity in and between the subthalamic nucleus and substantia nigra pars reticulata of Parkinson's disease patients
    Mahan Alavi
    Department of Physiology, University of Toronto, Toronto, ON, Canada
    Exp Neurol 245:60-71. 2013
    ....
  12. doi request reprint Movement related potentials and oscillatory activities in the human internal globus pallidus during voluntary movements
    Eric W Tsang
    Division of Brain Imaging and Behaviour Systems Neuroscience, Toronto Western Research Institute, University Health Network, Toronto, Canada
    J Neurol Neurosurg Psychiatry 83:91-7. 2012
    ..To study internal globus pallidus (GPi) activities and the interactions among the bilateral GPi and motor cortical areas during voluntary movements...
  13. doi request reprint Frequency-dependent effects of electrical stimulation in the globus pallidus of dystonia patients
    Liu D Liu
    Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Neurophysiol 108:5-17. 2012
    ....
  14. doi request reprint Oscillatory activity in the globus pallidus internus: comparison between Parkinson's disease and dystonia
    Moran Weinberger
    Department of Physiology, University of Toronto, Toronto, ON, Canada
    Clin Neurophysiol 123:358-68. 2012
    ....
  15. doi request reprint Microstimulation-induced inhibition as a tool to aid targeting the ventral border of the subthalamic nucleus
    Myriam Lafreniere-Roula
    Department of Physiology, University of Toronto, Ontario, Canada
    J Neurosurg 111:724-8. 2009
    ..The presence of inhibition in the SNr but not in the STN could be used as an additional criterion to help identify the location of the border between the STN and SNr...
  16. doi request reprint Deep brain stimulation of the ventral intermediate nucleus of the thalamus for tremor in patients with multiple sclerosis
    Cristina V Torres
    Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, University of Toronto, University Health Network, Toronto, Ontario, Canada
    Neurosurgery 67:646-51; discussion 651. 2010
    ..Tremor is an important cause of disability in patients with multiple sclerosis (MS). Deep brain stimulation (DBS) in the ventral intermediate nucleus (VIM) of the thalamus is said to be beneficial for MS tremor...
  17. doi request reprint The nature and time course of cortical activation following subthalamic stimulation in Parkinson's disease
    Renju Kuriakose
    Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada M5T 2S8
    Cereb Cortex 20:1926-36. 2010
    ..Cortical activation may be related to the clinical effects of STN DBS in PD...
  18. doi request reprint The dominant-STN phenomenon in bilateral STN DBS for Parkinson's disease
    Anna Castrioto
    Movement Disorders Center, Toronto Western Hospital, University of Toronto, University Health Network, Toronto, ON, Canada
    Neurobiol Dis 41:131-7. 2011
    ..In our sample 50% of the patients presented with a dominant-STN, suggesting that a non-negligible part of PD patients might not need bilateral STN-DBS surgery...
  19. doi request reprint Lateralization in intrinsic functional connectivity of the temporoparietal junction with salience- and attention-related brain networks
    Aaron Kucyi
    Division of Brain, Imaging and Behaviour Systems Neuroscience, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    J Neurophysiol 108:3382-92. 2012
    ..Our findings build on classic lesion and neuroimaging studies, demonstrating a complex spatial network organization of lateralization in TPJ functional connectivity in the absence of an overt stimulus...
  20. doi request reprint Anterior thalamus deep brain stimulation at high current impairs memory in rats
    Clement Hamani
    Division of Neurosurgery, Toronto Western Hospital, Toronto, Ontario, Canada
    Exp Neurol 225:154-62. 2010
    ..Though translating data from animals to humans has to be considered with caution, our study underscores the need for carefully monitoring memory function while selecting stimulation parameters during the clinical evaluation of AN DBS...
  21. doi request reprint Enhanced synchronization of thalamic theta band local field potentials in patients with essential tremor
    Abdoul Kane
    Department of Physiology, University of Toronto, Toronto, ON, Canada
    Exp Neurol 217:171-6. 2009
    ....
  22. doi request reprint Three-dimensional in vivo modeling of vestibular schwannomas and surrounding cranial nerves with diffusion imaging tractography
    David Qixiang Chen
    Division of Neurosurgery, Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada
    Neurosurgery 68:1077-83. 2011
    ..However, imaging of the CN fibers surrounding vestibular schwannomas has been limited with 2-dimensional imaging alone...
  23. doi request reprint Unilateral pallidal deep brain stimulation in a patient with cervical dystonia and tremor
    Cristina V Torres
    Division of Neurosurgery, Department of Surgery, Movement Disorders Center, Toronto Western Hospital, University of Toronto, University Health Network, Toronto, Ontario, Canada
    J Neurosurg 113:1230-3. 2010
    ..The authors report on a case of unilateral GPi implantation that resulted in sustained benefit with marked improvement in pain and dystonia...
  24. ncbi request reprint Deep brain stimulation for the treatment of epilepsy
    Clement Hamani
    Division of Neurosurgery Toronto Western Hospital University of Toronto, Division of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada
    Int J Neural Syst 19:213-26. 2009
    ..We review the published literature on DBS, cortical and cerebellar stimulation for the treatment of epilepsy focusing predominantly on the rationale and clinical outcome in each target...
  25. ncbi request reprint Saccade-related potentials recorded from human subthalamic nucleus
    Adrian P Fawcett
    Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ont, Canada
    Clin Neurophysiol 118:155-63. 2007
    ..To investigate an ocular motor role for the STN in Parkinson's disease (PD) patients...
  26. doi request reprint Clinical evaluation of stereotactic target localization using 3-Tesla MRI for radiosurgery planning
    Derek MacFadden
    University of Toronto Faculty of Medicine, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 76:1472-9. 2010
    ..The objectives of the present study were to spatially investigate the effect of 3-Tesla (3T) MRI on clinical target localization for stereotactic radiosurgery...
  27. ncbi request reprint Deep brain stimulation of the anterior nucleus of the thalamus: effects of electrical stimulation on pilocarpine-induced seizures and status epilepticus
    Clement Hamani
    Division of Neurosurgery, Toronto Western Hospital and University Health Network, University of Toronto, Toronto, Ontario, Canada
    Epilepsy Res 78:117-23. 2008
    ..As the optimal stimulation settings remain elusive, we studied the effects of different stimulation parameters against pilocarpine induced seizures and status epilepticus (SE)...
  28. ncbi request reprint Beta oscillatory activity in the subthalamic nucleus and its relation to dopaminergic response in Parkinson's disease
    Moran Weinberger
    Department of Physiology, Med Sci Building 3302, 1 King s College Circle, University of Toronto, Toronto, Ontario M5S 1A8, Canada
    J Neurophysiol 96:3248-56. 2006
    ..The study also suggests that LFP beta oscillatory activity is generated largely within the dorsal portion of the STN and can produce synchronous oscillatory activity of the local neuronal population...
  29. ncbi request reprint Bursting activity of neurons in the human anterior thalamic nucleus
    Mojgan Hodaie
    Division of Neurosurgery, University of Toronto, Toronto, ON M5S 1A8, Canada
    Brain Res 1115:1-8. 2006
    ..This study describes for the first time the properties of this nucleus in humans and may be important in furthering our knowledge of thalamic mechanisms of epileptogenesis...
  30. doi request reprint Complications of Gamma Knife surgery: an early report from 2 Canadian centers
    Shobhan Vachhrajani
    Division of Neurosurgery, University of Toronto, Ontario, Canada
    J Neurosurg 109:2-7. 2008
    ..The authors report treatment complications from the early experience of 2 Canadian GKS programs in Toronto and Sherbrooke...
  31. pmc Glioblastoma multiforme after stereotactic radiotherapy for acoustic neuroma: case report and review of the literature
    Anandh Balasubramaniam
    Arthur and Sonia Labatt Brain Tumor Center, Hospital for Sick Children, University of Toronto, 399 Bathurst St, 4W 446, Toronto, ON M5T 2S8, Canada
    Neuro Oncol 9:447-53. 2007
    ..However, the risk is not zero and requires discussion with the patient, with specific consideration in young patients and those with a cancer predisposition...
  32. doi request reprint Abnormal trigeminal nerve microstructure and brain white matter in idiopathic trigeminal neuralgia
    Danielle D Desouza
    Division of Brain, Imaging and Behaviour Systems Neuroscience, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada Institute of Medical Science, University of Toronto, Toronto, ON, Canada
    Pain 155:37-44. 2014
    ..These findings suggest that trigeminal nerve structural abnormalities occur in TN, even if not apparent on gross imaging. Furthermore, MD and RD findings suggest that neuroinflammation and edema may contribute to TN pathophysiology. ..
  33. pmc Hemispheric asymmetry in white matter connectivity of the temporoparietal junction with the insula and prefrontal cortex
    Aaron Kucyi
    Division of Brain, Imaging and Behaviour Systems Neuroscience, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    PLoS ONE 7:e35589. 2012
    ..The findings also have implications for our understanding of acute and chronic pains and stroke-induced spatial hemineglect...
  34. ncbi request reprint Chronic anterior thalamus stimulation for intractable epilepsy
    Mojgan Hodaie
    Division of Neurosurgery, University of Toronto, ON, Canada
    Epilepsia 43:603-8. 2002
    ..We investigated neuromodulation of the anterior thalamus by using deep-brain stimulation (DBS) in patients with intractable seizures...
  35. ncbi request reprint Advances in technology for intracranial stereotactic radiosurgery
    Arjun Sahgal
    Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, The Princess Margaret Hospital, and the Joey Toby Tanenbaum family Gamma Knife Center, University of Toronto, Toronto, Ontario, Canada
    Technol Cancer Res Treat 8:271-80. 2009
    ..The focus of this review is to highlight recent advances and major innovations in SRS technologies relevant to clinical practice and developments allowing for non-invasive frame SRS...
  36. ncbi request reprint Anesthesia for functional neurosurgery: review of complications
    Lakshmi Venkatraghavan
    Department of Anesthesia, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Neurosurg Anesthesiol 18:64-7. 2006
    ..Awareness and vigilance can improve the identification and early treatment of intraoperative complications such as seizures, loss of airway, and changes in the neurologic status...