Research Topics
| Margaret S HerridgeSummaryAffiliation: University of Toronto Country: Canada Publications
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Detail Information
Publications
The pathophysiology of long-term neuromuscular and cognitive outcomes following critical illnessMargaret S Herridge
Pulmonary and Critical Care Medicine, University of Toronto, Toronto General Hospital, Toronto, Ontario, Canada M5G 2C4
Crit Care Clin 24:179-99, x. 2008..Additionally, it presents a roadmap outlining future directions in this area of research...
Legacy of intensive care unit-acquired weaknessMargaret S Herridge
Respiratory and Critical Care Medicine, Inter Departmental Division of Critical Care Medicine, University Health Network, University of Toronto, Toronto, ON, Canada
Crit Care Med 37:S457-61. 2009..These data are crucial to inform risk-stratification and future rehabilitation interventions, both during the intensive care unit admission and after hospital discharge as patients reintegrate within their community and workplace...
The challenge of designing a post-critical illness rehabilitation interventionMargaret S Herridge
Interdepartmental Division of Critical Care, University of Toronto, University Health Network, 585 University Avenue, 11C 1180, Toronto, ON M5G 2C4, Canada
Crit Care 15:1002. 2011....
Study protocol: The Improving Care of Acute Lung Injury Patients (ICAP) studyDale M Needham
Johns Hopkins University, 5th Floor, 1830 East Monument Street, Baltimore, MD 21205, USA
Crit Care 10:R9. 2006....
Recovery and long-term outcome in acute respiratory distress syndromeMargaret S Herridge
Division of Respiratory and Interdepartmental Division of Critical Care Medicine, Toronto General Hospital, University of Toronto, 11C 1180 585 University Avenue, Toronto, Ontario M5G 2C4, Canada
Crit Care Clin 27:685-704. 2011....
Functional disability 5 years after acute respiratory distress syndromeMargaret S Herridge
Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada
N Engl J Med 364:1293-304. 2011..There have been few detailed, in-person interviews and examinations to obtain follow-up data on 5-year outcomes among survivors of the acute respiratory distress syndrome (ARDS)...
Mobile, awake and critically illMargaret S Herridge
Department of Respiratory and Critical Care Medicine, University Health Network, University of Toronto, Toronto, Ont
CMAJ 178:725-6. 2008
Prognostication and intensive care unit outcome: the evolving role of scoring systemsMargaret S Herridge
University Health Network, Department of Medicine, University of Toronto, Toronto, ON, Canada
Clin Chest Med 24:751-62. 2003..These current and developing applications will help us to further understand the link between ICU severity of illness and long-term morbidity as we move beyond survival as the sole measure of ICU outcome...
Autopsy in critical illness: is it obsolete?Margaret S Herridge
Assistant Professor of Medicine, University of Toronto, Pulmonary and Critical Care, Toronto General Hospital, Toronto, Ontario, Canada
Crit Care 7:407-8. 2003
One-year outcomes in survivors of the acute respiratory distress syndromeMargaret S Herridge
Department of Medicine, University Health Network, Toronto, Ont, Canada
N Engl J Med 348:683-93. 2003..As more patients survive the acute respiratory distress syndrome, an understanding of the long-term outcomes of this condition is needed...
Long-term outcomes after critical illnessMargaret S Herridge
Department of Respiratory and Critical Care Medicine, University of Toronto, Toronto General Hospital, Toronto, Ontario, Canada
Curr Opin Crit Care 8:331-6. 2002..We need to gain a better understanding of the specific determinants of patients' inability to resume their prior work/lifestyle so that an appropriate multidisciplinary intervention can be designed and tested...
Self-reported depressive symptoms and memory complaints in survivors five years after ARDSNeill K J Adhikari
Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada
Chest 140:1484-93. 2011..Survivors of ARDS report depressive symptoms and memory complaints, the prevalence of which after 5 years is unknown...
Two-year outcomes, health care use, and costs of survivors of acute respiratory distress syndromeAngela M Cheung
Department of Medicine, University Health Network, Toronto, ON, Canada
Am J Respir Crit Care Med 174:538-44. 2006..Little is known about the long-term outcomes and costs of survivors of acute respiratory distress syndrome (ARDS)...
Intensive care unit-acquired weakness: clinical phenotypes and molecular mechanismsJane Batt
Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario, Canada
Am J Respir Crit Care Med 187:238-46. 2013....
Difference in reported pre-morbid health-related quality of life between ARDS survivors and their substitute decision makersDamon C Scales
Department of Critical Care Medicine, Sunnybrook and Women s Health Sciences Centre, 2075 Bayview Avenue, M4N 3M5, Toronto, Canada
Intensive Care Med 32:1826-31. 2006..Substitute decision makers may consider the pre-morbid health status of their critically ill loved one when making treatment decisions on her/his behalf...
Integrating Mortality and Morbidity Outcomes: Using Quality-adjusted Life Years in Critical Care TrialsNiall D Ferguson
Department of Critical Care Medicine, Sunnybrook Health Science Centre, 2075 Bayview Avenue, Room D108, Toronto, ON, M4N 3M5 Canada
Am J Respir Crit Care Med 187:256-61. 2013....
Self-reported symptoms of depression and memory dysfunction in survivors of ARDSNeill K J Adhikari
Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
Chest 135:678-87. 2009..Survivors of ARDS have well documented physical limitations, but psychological effects are less clear. We determined the prevalence of self-reported depression and memory dysfunction in ARDS survivors...
Education and support needs during recovery in acute respiratory distress syndrome survivorsChristie M Lee
Division of Respirology, University of Toronto, 1 King s College Circle, 6263 Medical Sciences Building, Toronto, ON M5S 1A8, Canada
Crit Care 13:R153. 2009..The Timing it Right (TIR) framework, which emphasizes ARDS survivors' journey from the ICU through to community re-integration, may provide a valuable construct to explore the support needs of ARDS survivors during their recovery...
Physical consequences of critical illnessSubarna Thirugnanam
Department of Medicine, University of Toronto, Ontario, Canada
Br J Hosp Med (Lond) 68:477-81. 2007....
Long-term outcome after acute lung injuryCatherine L Hough
Pulmonary and Critical Care Medicine, Department of Medicine, Harborview Medical Center, University of Washington, Seattle, Washington, USA
Curr Opin Crit Care 18:8-15. 2012..In this review, we will discuss recent studies that add to our knowledge of long-term outcomes after ALI and critical illness...
Lung function and quality of life in survivors of the acute respiratory distress syndrome (ARDS)M Elizabeth Wilcox
University of Toronto, Toronto Western Hospital, Division of Pulmonary and Critical Care Medicine, Toronto, Ontario, Canada
Presse Med 40:e595-603. 2011..Future research should focus on identifying patients at risk for long-term functional limitations and the design of rehabilitation interventions tailored to individual patient needs...
One-year outcomes and health care utilization in survivors of severe acute respiratory syndromeCatherine M Tansey
Department of Medicine, University Health Network, and Mount Sinai Hospital, Toronto, Ontario, Canada
Arch Intern Med 167:1312-20. 2007..Research conducted during the SARS outbreak may help inform research planning for future public health emergencies. The objective of this study was to evaluate the 1-year outcomes in survivors of SARS and their family caregivers...
Well-being in informal caregivers of survivors of acute respiratory distress syndromeJill I Cameron
University Health Network, Women's Health Program, Toronto, ON
Crit Care Med 34:81-6. 2006..New approaches, such as family-centered rehabilitation, caregiver education, improved respite, and home care, may benefit informal caregivers...
Chronic sleep disorders in survivors of the acute respiratory distress syndromeChristie M Lee
Department of Medicine, University of Toronto, Toronto, Canada
Intensive Care Med 35:314-20. 2009..Poor sleep quality likely continues following discharge from hospital in several patients and becomes a chronic disorder in some. The aim of this study was to describe the etiology of chronic sleep complaints in survivors of ARDS...
A retrospective cohort pilot study to evaluate a triage tool for use in a pandemicMichael D Christian
Department of National Defence, Canadian Forces, Mount Sinai Hospital Toronto University Health Network, University of Toronto, 600 University Avenue, Toronto, ON, Canada
Crit Care 13:R170. 2009....
Long-term outcomes in patients surviving acute respiratory distress syndromeM Elizabeth Wilcox
Division of Pulmonary and Critical Care Medicine, Toronto Western Hospital, Toronto, Ontario, Canada
Semin Respir Crit Care Med 31:55-65. 2010..Clinicians, caregivers, and patients should be made aware of the deleterious long-term effects of the intensive care unit stay because they are currently poorly recognized and potentially modifiable...
Neuromuscular function in survivors of the acute respiratory distress syndromeMichael J Angel
Department of Medicine, Division of Neurology, University Health Network, University of Toronto, Toronto, Ontario, Canada
Can J Neurol Sci 34:427-32. 2007..Persistent neuromuscular complications of ARDS may contribute to the functional disability observed in these patients...
Review of retention strategies in longitudinal studies and application to follow-up of ICU survivorsCatherine M Tansey
Department of Medicine, Toronto General Hospital, University Health Network, 585 University Ave, ON M5G 2N2, Toronto, Canada
Intensive Care Med 33:2051-7. 2007....
Relationship between premortem and postmortem diagnosis in critically ill bone marrow transplantation patientsFatma Al-Saidi
Department of Medicine, University of Toronto, University Health Network, Canada
Crit Care Med 30:570-3. 2002..Reliance on clinical diagnosis may be valid for withdrawal of active treatment decision-making in these patients...
Early intensive care unit mobility: future directionsPeter E Morris
Section on Pulmonary, Critical Care, Allergy, and Immunologic Diseases, Wake Forest University School of Medicine, Gray Building, Room 3141, Medical Center Boulevard, Winston Salem, NC 27157, USA
Crit Care Clin 23:97-110. 2007..Finally, we present a "roadmap" outlining future directions moving toward the development and testing of early ICU mobility therapies...
Quality of life in adult survivors of critical illness: a systematic review of the literatureDavid W Dowdy
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Intensive Care Med 31:611-20. 2005..This systematic review provides a general understanding of QOL following critical illness and can serve as a standard of comparison for QOL studies in specific ICU subpopulations...
Studying outcomes of intensive care unit survivors: the role of the cohort studyDavid W Dowdy
School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
Intensive Care Med 31:914-21. 2005..CONCLUSIONS: We make recommendations for the design of future cohort studies to maximize the impact of this research in improving the long-term outcomes of critically ill patients...
Quality of life, emotional abnormalities, and cognitive dysfunction in survivors of acute lung injury/acute respiratory distress syndromeRamona O Hopkins
Department of Medicine, Pulmonary and Critical Care Division, LDS Hospital, Salt Lake City, UT 84143, USA
Clin Chest Med 27:679-89; abstract x. 2006..Its main focus is a review of the current knowledge concerning cognitive and emotional outcomes after lung injury and their impact on long-term quality of life...
Quality of life after acute respiratory distress syndrome: a meta-analysisDavid W Dowdy
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Intensive Care Med 32:1115-24. 2006..CONCLUSIONS: ARDS survivors in different clinical settings experience similar decrements in QOL. The precise magnitude of these decrements helps clarify the long-term prognosis for ARDS survivors...
Long-term outcomes after critical illness: past, present, futureMargaret S Herridge
Curr Opin Crit Care 13:473-5. 2007
Studying outcomes of intensive care unit survivors: measuring exposures and outcomesDale M Needham
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
Intensive Care Med 31:1153-60. 2005..There is little systematic guidance for measuring these outcomes and exposures within the ICU setting. As a result measurement methods are often variable and non-comparable across studies...
Development of a triage protocol for critical care during an influenza pandemicMichael D Christian
Division of Infectious Diseases and Critical Care, Department of Postgraduate Medicine, McMaster University, Hamilton, Ont
CMAJ 175:1377-81. 2006..Of particular concern in this planning is the allocation of resources, such as ventilators and antiviral medications, which will likely become scarce during a pandemic...
Epidemiology and outcomes of acute lung injuryGordon D Rubenfeld
Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, 325 Ninth Ave, Seattle WA 98104, USA
Chest 131:554-62. 2007....
Acute lung injury--affecting many livesMargaret S Herridge
N Engl J Med 353:1736-8. 2005
