Cheryl A Hawkes

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Immunotherapy as treatment for Alzheimer's disease
    Cheryl A Hawkes
    Center for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada
    Expert Rev Neurother 7:1535-48. 2007
  2. doi request reprint Small molecule beta-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer's disease
    Cheryl A Hawkes
    Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada
    Eur J Neurosci 31:203-13. 2010
  3. ncbi request reprint In vivo uptake of β-amyloid by non-plaque associated microglia
    Cheryl A Hawkes
    Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada
    Curr Alzheimer Res 9:890-901. 2012
  4. ncbi request reprint Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model
    JoAnne McLaurin
    Centre for Research in Neurodegenerative Diseases, 6 Queen s Park Crescent West, Toronto, Ontario M5S 3H2 Canada
    Nat Med 12:801-8. 2006
  5. pmc Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy
    Cheryl A Hawkes
    Centre for Research in Neurodegenerative, University of Toronto, Toronto, Ontario, Canada M5S 3H2
    Proc Natl Acad Sci U S A 106:1261-6. 2009
  6. doi request reprint Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer's disease
    Adrienne Dorr
    Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario, Canada
    Brain 135:3039-50. 2012
  7. doi request reprint Synthesis of scyllo-inositol derivatives and their effects on amyloid beta peptide aggregation
    Yedi Sun
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ont, Canada M5S 3H6
    Bioorg Med Chem 16:7177-84. 2008
  8. pmc Expression microarray analysis implicates apoptosis and interferon-responsive mechanisms in susceptibility to experimental cerebral malaria
    Fiona E Lovegrove
    Institute of Medical Science, University of Toronto, Toronto, ON, Canada M5G 2C4
    Am J Pathol 171:1894-903. 2007

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Immunotherapy as treatment for Alzheimer's disease
    Cheryl A Hawkes
    Center for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada
    Expert Rev Neurother 7:1535-48. 2007
    ....
  2. doi request reprint Small molecule beta-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer's disease
    Cheryl A Hawkes
    Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada
    Eur J Neurosci 31:203-13. 2010
    ..These results suggest that Abeta aggregation can be targeted at multiple points along the kinetic pathway for the improvement of Alzheimer's disease-like pathology...
  3. ncbi request reprint In vivo uptake of β-amyloid by non-plaque associated microglia
    Cheryl A Hawkes
    Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada
    Curr Alzheimer Res 9:890-901. 2012
    ..These results reveal a novel, beneficial role for non-plaque associated microglia in the regulation of cerebral Aβ levels in a mouse model of AD...
  4. ncbi request reprint Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model
    JoAnne McLaurin
    Centre for Research in Neurodegenerative Diseases, 6 Queen s Park Crescent West, Toronto, Ontario M5S 3H2 Canada
    Nat Med 12:801-8. 2006
    ....
  5. pmc Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy
    Cheryl A Hawkes
    Centre for Research in Neurodegenerative, University of Toronto, Toronto, Ontario, Canada M5S 3H2
    Proc Natl Acad Sci U S A 106:1261-6. 2009
    ....
  6. doi request reprint Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer's disease
    Adrienne Dorr
    Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario, Canada
    Brain 135:3039-50. 2012
    ....
  7. doi request reprint Synthesis of scyllo-inositol derivatives and their effects on amyloid beta peptide aggregation
    Yedi Sun
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ont, Canada M5S 3H6
    Bioorg Med Chem 16:7177-84. 2008
    ..The other derivatives showed some alterations in the morphology of the Abeta42 fibers produced. These findings indicate the importance of all of the hydroxyl groups of scyllo-inositol for complete inhibition of Abeta aggregation...
  8. pmc Expression microarray analysis implicates apoptosis and interferon-responsive mechanisms in susceptibility to experimental cerebral malaria
    Fiona E Lovegrove
    Institute of Medical Science, University of Toronto, Toronto, ON, Canada M5G 2C4
    Am J Pathol 171:1894-903. 2007
    ....