Research Topics
| Lisa HartlingSummaryAffiliation: University of Alberta Country: Canada Publications
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Detail Information
Publications
Abstracts of randomized controlled trials presented at the society for pediatric research meeting: an example of publication biasTerry P Klassen
Department of Pediatrics, University of Alberta, 2C3 67 Walter C Mackenzie Centre, Edmonton, Alberta, Canada T6G 2B7
Arch Pediatr Adolesc Med 156:474-9. 2002..The increased interest in meta-analyses has highlighted the need to identify the totality of evidence when addressing treatment questions...
A descriptive analysis of overviews of reviews published between 2000 and 2011Lisa Hartling
Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
PLoS ONE 7:e49667. 2012..Overviews of systematic reviews compile data from multiple systematic reviews (SRs) and are a new method of evidence synthesis...
From the trenches: a cross-sectional study applying the GRADE tool in systematic reviews of healthcare interventionsLisa Hartling
Department of Pediatrics, Alberta Research Centre for Health Evidence, University of Alberta, Edmonton, Canada
PLoS ONE 7:e34697. 2012..GRADE was developed to address shortcomings of tools to rate the quality of a body of evidence. While much has been published about GRADE, there are few empirical and systematic evaluations...
Antipsychotics in adults with schizophrenia: comparative effectiveness of first-generation versus second-generation medications: a systematic review and meta-analysisLisa Hartling
University of Alberta, Edmonton, Alberta, Canada
Ann Intern Med 157:498-511. 2012..Debate continues about the comparative benefits and harms of first-generation antipsychotics (FGAs) and second-generation antipsychotics (SGAs) in treating schizophrenia...
Testing a tool for the classification of study designs in systematic reviews of interventions and exposures showed moderate reliability and low accuracyLisa Hartling
Department of Pediatrics, Alberta Research Center for Health Evidence and the University of Alberta Evidence based Practice Center, University of Alberta, 11402 University Avenue, Edmonton, Alberta, Canada
J Clin Epidemiol 64:861-71. 2011..To develop and test a study design classification tool...
Problem-based learning in pre-clinical medical education: 22 years of outcome researchLisa Hartling
University of Alberta, Edmonton, Alberta, Canada
Med Teach 32:28-35. 2010..To conduct a systematic review of problem-based learning (PBL) in undergraduate, pre-clinical medical education...
Storytelling as a communication tool for health consumers: development of an intervention for parents of children with croup. Stories to communicate health informationLisa Hartling
Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Canada
BMC Pediatr 10:64. 2010..The objective of this paper is to describe the development of a story-based intervention for delivery of health evidence to parents of children with croup for use in a randomized controlled trial...
A systematic review of interventions to prevent childhood farm injuriesLisa Hartling
Alberta Research Centre for Child Health Evidence, Department of Pediatrics, University of Alberta, Room 9424, 11402 University Ave, Edmonton, Alberta, Canada T6J 2G3
Pediatrics 114:e483-96. 2004..A specific focus was the effectiveness of the North American Guidelines for Children's Agricultural Tasks...
Applying the risk of bias tool in a systematic review of combination long-acting beta-agonists and inhaled corticosteroids for persistent asthmaLisa Hartling
Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
PLoS ONE 6:e17242. 2011....
Steroids and bronchodilators for acute bronchiolitis in the first two years of life: systematic review and meta-analysisLisa Hartling
Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, 11402 University Avenue, Edmonton, AB, Canada T6G 2J3
BMJ 342:d1714. 2011..To evaluate and compare the efficacy and safety of bronchodilators and steroids, alone or combined, for the acute management of bronchiolitis in children aged less than 2 years...
Risk of bias versus quality assessment of randomised controlled trials: cross sectional studyLisa Hartling
Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, Aberhart Centre One, Edmonton, AB, Canada T6G 2J3
BMJ 339:b4012. 2009....
Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysisNina Buscemi
University of Alberta Capital Health Evidence Based Practice Centre, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada T6G 2J3
BMJ 332:385-93. 2006..To conduct a systematic review of the efficacy and safety of exogenous melatonin in managing secondary sleep disorders and sleep disorders accompanying sleep restriction, such as jet lag and shiftwork disorder...
A descriptive analysis of a representative sample of pediatric randomized controlled trials published in 2007Michele P Hamm
Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Canada
BMC Pediatr 10:96. 2010..Our objectives were to provide an overview of a representative sample of pediatric RCTs published in 2007 and assess the validity of their results...
Systematic review of knowledge translation strategies in the allied health professionsShannon D Scott
Faculty of Nursing, University of Alberta, Level 3, Edmonton Clinic Health Academy, Edmonton, AB, Canada
Implement Sci 7:70. 2012....
Systematic review: nonoperative and operative treatments for rotator cuff tearsJennifer C Seida
Alberta Research Centre for Health Evidence, University of Alberta, Edmonton, Alberta, Canada
Ann Intern Med 153:246-55. 2010..Many approaches exist for managing rotator cuff tears...
Factors influencing the publication of randomized controlled trials in child health researchLisa Hartling
Alberta Research Centre for Child Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Canada
Arch Pediatr Adolesc Med 158:983-7. 2004..Publication bias threatens the validity of clinical decisions. The root causes are relatively unknown, and there is limited investigation in child research literature...
Children in reviews: methodological issues in child-relevant evidence synthesesKristie Cramer
Alberta Research Centre for Child Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
BMC Pediatr 5:38. 2005....
Treatment in the pediatric emergency department is evidence based: a retrospective analysisKellie L Waters
Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
BMC Pediatr 6:26. 2006..Further, we wished to ascertain what percentage of evidence for treatment provided in the PED comes from pediatric studies...
Do health care institutions value research? A mixed methods study of barriers and facilitators to methodological rigor in pediatric randomized trialsMichele P Hamm
Alberta Research Centre for Health Evidence, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada
BMC Med Res Methodol 12:158. 2012..Pediatric randomized controlled trials (RCTs) are susceptible to a high risk of bias. We examined the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials...
Systematic review data extraction: cross-sectional study showed that experience did not increase accuracyJennifer Horton
Department of Pediatrics, University of Alberta Capital Health Evidence Based Practice Centre, Edmonton Alberta, Canada
J Clin Epidemiol 63:289-98. 2010..This study assessed the impact of systematic review and data extraction experience on the accuracy and efficiency of data extraction in systematic reviews...
Systematic reviews of psychosocial interventions for autism: an umbrella reviewJennifer Krebs Seida
Alberta Research Centre for Health Evidence, University of Alberta, Edmonton, Alberta, Canada
Dev Med Child Neurol 51:95-104. 2009..We conducted an umbrella review of systematic reviews of the effectiveness of psychosocial interventions for ASD...
Single data extraction generated more errors than double data extraction in systematic reviewsNina Buscemi
Department of Pediatrics, University of Alberta Capital Health Evidence Based Practice Centre, Edmonton, Alberta T6G 2J3, Canada
J Clin Epidemiol 59:697-703. 2006..To conduct a pilot study to compare the frequency of errors that accompany single vs. double data extraction, compare the estimate of treatment effect derived from these methods, and compare the time requirements for these methods...
Social Stories ™ to improve social skills in children with autism spectrum disorder: a systematic reviewMohammad Karkhaneh
Department of Pediatrics, University of Alberta, Edmonton, Canada
Autism 14:641-62. 2010..This review underscores the need for further rigorous research and highlights some outstanding questions regarding maintenance and generalization of the benefits of Social Stories ™...
The efficacy and safety of exogenous melatonin for primary sleep disorders. A meta-analysisNina Buscemi
Capital Health Evidence based Practice Centre, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada
J Gen Intern Med 20:1151-8. 2005..Exogenous melatonin has been increasingly used in the management of sleep disorders...
A descriptive analysis of child-relevant systematic reviews in the Cochrane Database of Systematic ReviewsSimon Bow
Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
BMC Pediatr 10:34. 2010..The objective of this study was to describe child-relevant SRs from the Cochrane Database of Systematic Reviews (CDSR, Issue 2, 2009)...
Meta-analysis: secondary prevention programs for patients with coronary artery diseaseAlexander M Clark
University of Alberta Evidence-based Practice Center, Edmonton, Alberta, Canada
Ann Intern Med 143:659-72. 2005..CONCLUSIONS: A wide variety of secondary prevention programs improve health outcomes in patients with coronary disease...
A systematic review of crisis interventions used in the emergency department: recommendations for pediatric care and researchMichele P Hamm
Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
Pediatr Emerg Care 26:952-62. 2010..In this systematic review, we evaluated the effectiveness of emergency department (ED)-based management interventions for mental health presentations with an aim to provide recommendations for pediatric care...
A systematic review of intravenous gamma globulin for therapy of acute myocarditisJoan L Robinson
Department of Pediatrics, Stollery Children s Hospital and University of Alberta, Edmonton, Alberta, Canada
BMC Cardiovasc Disord 5:12. 2005..Intravenous gamma globulin (IVGG) is commonly used in the management of acute myocarditis. The objective of this study was to systematically review the literature evaluating this practice...
Epinephrine for bronchiolitisLisa Hartling
Department of Pediatrics, University of Alberta, Aberhart Centre One, Room 9424, 11402 University Avenue, Edmonton, Alberta, Canada, T6G 2J3
Cochrane Database Syst Rev 6:CD003123. 2011..Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness...
Instruments to detect alcohol and other drug misuse in the emergency department: a systematic reviewAmanda S Newton
Department of Pediatrics, Faculty of Medicine and Dentistry, 8213 Aberhart Centre One, 11402 University Ave, Edmonton, Alberta, Canada T6G 2J3
Pediatrics 128:e180-92. 2011..Screening instruments that rapidly identify patients who require further diagnostic evaluation and/or brief intervention are critically important...
Which resources should be used to identify RCT/CCTs for systematic reviews: a systematic reviewEllen T Crumley
HealthInfo and Searching Practice Inc, Edmonton, Canada
BMC Med Res Methodol 5:24. 2005..This systematic review was conducted in order to assess the value of different resources to identify trials for inclusion in systematic reviews...
Challenges in systematic reviews of therapeutic devices and proceduresLisa Hartling
Capital Health Evidence-based Practice Center, University of Alberta, Edmonton, Canada
Ann Intern Med 142:1100-11. 2005....
Secondary prevention programmes for coronary heart disease: a meta-regression showing the merits of shorter, generalist, primary care-based interventionsAlexander M Clark
Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada
Eur J Cardiovasc Prev Rehabil 14:538-46. 2007..The aim of this study was to determine which programme characteristics influence the effectiveness of secondary prevention programmes for Coronary Heart Disease...
Heat loss prevention: a systematic review of occlusive skin wrap for premature neonatesKristie Cramer
Complementary and Alternative Research and Education Program, Department of Pediatrics, University of Alberta, Alberta, Canada
J Perinatol 25:763-9. 2005..76, 95% CI 0.51, 1.13). CONCLUSIONS:The findings suggest that occlusive skin wrap prevents heat loss in premature infants. The meta-analysis lacked the power to provide definitive results regarding the effect of wrap on mortality...
Behavioural and developmental interventions for autism spectrum disorder: a clinical systematic reviewMaria B Ospina
Alberta Research Centre for Health Evidence, University of Alberta, Edmonton, Alberta, Canada
PLoS ONE 3:e3755. 2008..We conducted a systematic review to summarize the evidence on the effectiveness of behavioural and developmental interventions for ASD...
Bridging the gap between clinical research and knowledge translation in pediatric emergency medicineLisa Hartling
Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
Acad Emerg Med 14:968-77. 2007....
Music for pain and anxiety in children undergoing medical procedures: a systematic review of randomized controlled trialsJeffrey A Klassen
From the Alberta Research Center for Child Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Canada
Ambul Pediatr 8:117-28. 2008..The aim of this study was to conduct a systematic review of the efficacy of music therapy (MT) on pain and anxiety in children undergoing clinical procedures...
Meta-analyses of safety data: a comparison of exact versus asymptotic methodsBen Vandermeer
University of Alberta Evidence Based Practice Centre, Alberta Research Centre for Health Evidence
Stat Methods Med Res 18:421-32. 2009..Asymptotic methods will not always be a good approximation for exact methods in safety meta-analyses. Event rates and number of studies should be closely examined when choosing the statistical method for combining rare event data...
Systematic review: cardiac resynchronization in patients with symptomatic heart failureFinlay A McAlister
The University of Alberta and Capital Health Evidence based Practice Center, Edmonton, Alberta, Canada
Ann Intern Med 141:381-90. 2004..Even with optimal pharmacotherapy, symptomatic heart failure is associated with substantial morbidity and mortality...
Oral rehydration versus intravenous therapy for treating dehydration due to gastroenteritis in children: a meta-analysis of randomised controlled trialsSteven Bellemare
Alberta Research Centre for Child Health Evidence, Department of Pediatrics, University of Alberta, 2C3, 00 WMC, Edmonton, Alberta, Canada, T6G 2R7
BMC Med 2:11. 2004..We conducted a systematic review of randomised controlled trials (RCTs) to compare ORT and intravenous therapy (IVT) for the treatment of dehydration secondary to acute gastroenteritis in children...
Chorioamnionitis as a risk factor for bronchopulmonary dysplasia: a systematic review and meta-analysisLisa Hartling
Department of Pediatrics, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, Ontario, Canada
Arch Dis Child Fetal Neonatal Ed 97:F8-F17. 2012..To conduct a systematic review of the association between chorioamnionitis (CA) and bronchopulmonary dysplasia (BPD) in preterm infants...
Tissue adhesives for traumatic lacerations: a systematic review of randomized controlled trialsKen J Farion
Department of Pediatrics, University of Ottawa, Children s Hospital of Eastern Ontario, Ottawa, Canada
Acad Emerg Med 10:110-8. 2003..To summarize the best available evidence for the effect of tissue adhesives (TAs) in managing traumatic lacerations in children and adults...
Acyclovir for treating varicella in otherwise healthy children and adolescents: a systematic review of randomised controlled trialsTerry P Klassen
Alberta Research Center for Child Health Evidence, Department of Pediatrics, University of Alberta, 2C3, 00 WMC, Edmonton, Alberta, T6G 2R7, Canada
BMC Pediatr 2:9. 2002..We conducted a systematic review of randomised controlled trials that evaluated acyclovir for the treatment of chickenpox in otherwise healthy children...
A systematic review of intentional delivery in women with preterm prelabor rupture of membranesLisa Hartling
Department of Obstetrics and Gynecology, University of Alberta, Edmonton, Canada
J Matern Fetal Neonatal Med 19:177-87. 2006..Large multicenter trials with primary neonatal outcomes are required to assess whether intentional delivery is associated with less neonatal morbidity...
Parenteral ω-3 fatty acid lipid emulsions for children with intestinal failure and other conditions: a systematic reviewJennifer C Seida
Alberta Research Centre for Health Evidence, University of Alberta, Edmonton, AB, Canada
JPEN J Parenter Enteral Nutr 37:44-55. 2013..The authors systematically reviewed the evidence on the benefits and safety of n-3FA compared with standard lipid emulsions in children with intestinal disease, critical illness, trauma, or postoperative complications...
A meta-analysis of randomized controlled trials evaluating the efficacy of epinephrine for the treatment of acute viral bronchiolitisLisa Hartling
Alberta Research Center for Child Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, USA
Arch Pediatr Adolesc Med 157:957-64. 2003..There is insufficient evidence to support the use of epinephrine among inpatients. Large, multicentered trials are required before routine use among outpatients can be strongly recommended...
A protocol for a systematic review of knowledge translation strategies in the allied health professionsShannon D Scott
Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada
Implement Sci 6:58. 2011..Our objective in this study is to systematically review published research on KT strategies in five allied health disciplines...
Graduated driver licensing for reducing motor vehicle crashes among young driversKelly F Russell
Department of Pediatrics, University of Alberta, Aberhart Centre One, Room 9424, 11402 University Avenue, Edmonton, Alberta, Canada, T6G 2J3
Cochrane Database Syst Rev 10:CD003300. 2011..Graduated driver licensing (GDL) has been proposed as a means of reducing crash rates among novice drivers by gradually introducing them to higher risk driving situations...
The effects of audience response systems on learning outcomes in health professions education. A BEME systematic review: BEME Guide No. 21Cody Nelson
University of Alberta, Edmonton, Canada
Med Teach 34:e386-405. 2012..Although ARS may have pedagogical value, their impact is still unclear. This systematic review aims to examine the effect of ARS on learning outcomes in health professions education...
Treatment of hepatitis C in children: a systematic reviewJia Hu
Department of Pediatrics, University of Alberta, Edmonton, Canada
PLoS ONE 5:e11542. 2010..Current guidelines recommend children be treated for hepatitis C virus (HCV) using the same principles applied in adults. There are however few published studies which assess the efficacy and safety of HCV therapy in children...
Economic burden of agricultural machinery injuries in Ontario, 1985 to 1996Alison R Locker
Center for Health Services and Policy Research, Queen's University, Kingston, ON, Canada
J Rural Health 19:285-91. 2003..CONCLUSIONS: Costing information about agricultural injuries provides support for the prioritization and development of injury-control initiatives...
Derivation of a clinical decision rule for whiplash associated disorders among individuals involved in rear-end collisionsLisa Hartling
Department of Emergency Medicine, Queen's University, Kingston General Hospital, Ont, Canada
Accid Anal Prev 34:531-9. 2002..5% (95% confidence interval: 86.5, 96.6) and a specificity of 51.4% (44.7, 58.1). This study confirmed the importance of several risk factors for whiplash associated disorder following rear-end motor vehicle collisions...
A randomized controlled trial of an educational intervention to prevent the chronic pain of whiplash associated disorders following rear-end motor vehicle collisionsRobert J Brison
Department of Emergency Medicine, Queen s University, Kingston, Ontario, Canada
Spine (Phila Pa 1976) 30:1799-807. 2005..Concealed allocation, multicenter, single-blind, randomized controlled clinical trial...
