D A Hanley

Summary

Affiliation: University of Calgary
Country: Canada

Publications

  1. doi request reprint Does a high dietary acid content cause bone loss, and can bone loss be prevented with an alkaline diet?
    David A Hanley
    Division of Endocrinology and Metabolism, Departments of Medicine, Community Health Sciences and Oncology, University of Calgary, Calgary, AB, Canada Electronic address
    J Clin Densitom 16:420-5. 2013
  2. pmc Denosumab: mechanism of action and clinical outcomes
    D A Hanley
    Departments of Medicine, Community Health Sciences and Oncology, University of Calgary, Calgary, AL, Canada
    Int J Clin Pract 66:1139-46. 2012
  3. pmc Causal assessment of dietary acid load and bone disease: a systematic review & meta-analysis applying Hill's epidemiologic criteria for causality
    Tanis R Fenton
    Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada
    Nutr J 10:41. 2011
  4. pmc Phosphate decreases urine calcium and increases calcium balance: a meta-analysis of the osteoporosis acid-ash diet hypothesis
    Tanis R Fenton
    Clinical Nutrition, Alberta Health Services, Calgary, AB, Canada
    Nutr J 8:41. 2009
  5. pmc A randomized controlled trial of vitamin D dosing strategies after acute hip fracture: no advantage of loading doses over daily supplementation
    Alexandra Papaioannou
    McMaster University, HHSC, St Peter s Hospital Juravinski Research Centre, 88 Maplewood Avenue Hamilton, ON L8M 1W9, Canada
    BMC Musculoskelet Disord 12:135. 2011
  6. pmc Treatment of osteoporosis in an older home care population
    Shelly A Vik
    Department of Community Health Sciences University of Calgary, Calgary AB, Canada
    BMC Musculoskelet Disord 6:7. 2005
  7. pmc Low urine pH and acid excretion do not predict bone fractures or the loss of bone mineral density: a prospective cohort study
    Tanis R Fenton
    Department of Community Health Sciences, Faculty of Medicine, University of Calgary TRW Building, 3rd Floor, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6, Canada
    BMC Musculoskelet Disord 11:88. 2010
  8. pmc Dietary patterns in Canadian men and women ages 25 and older: relationship to demographics, body mass index, and bone mineral density
    Lisa Langsetmo
    Dalla Lana School of Public Health, University of Toronto, 155 College St, Toronto, ON, Canada
    BMC Musculoskelet Disord 11:20. 2010
  9. pmc Evaluation of easily measured risk factors in the prediction of osteoporotic fractures
    Robert Bensen
    Medical Science, McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 6:47. 2005
  10. ncbi request reprint Vitamin D insufficiency in North America
    David A Hanley
    Division of Endocrinology and Metabolism, Departments of Medicine and Oncology, University of Calgary Faculty of Medicine, Calgary, Alberta, Canada
    J Nutr 135:332-7. 2005

Detail Information

Publications65

  1. doi request reprint Does a high dietary acid content cause bone loss, and can bone loss be prevented with an alkaline diet?
    David A Hanley
    Division of Endocrinology and Metabolism, Departments of Medicine, Community Health Sciences and Oncology, University of Calgary, Calgary, AB, Canada Electronic address
    J Clin Densitom 16:420-5. 2013
    ..In the elderly, inadequate protein intake is a greater problem for bone health than protein excess. ..
  2. pmc Denosumab: mechanism of action and clinical outcomes
    D A Hanley
    Departments of Medicine, Community Health Sciences and Oncology, University of Calgary, Calgary, AL, Canada
    Int J Clin Pract 66:1139-46. 2012
    ..To describe the mechanisms of action of denosumab, a novel antiresorptive agent, contrasting it with other antiresorptive and anabolic osteoporosis treatments...
  3. pmc Causal assessment of dietary acid load and bone disease: a systematic review & meta-analysis applying Hill's epidemiologic criteria for causality
    Tanis R Fenton
    Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada
    Nutr J 10:41. 2011
    ..The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill's criteria...
  4. pmc Phosphate decreases urine calcium and increases calcium balance: a meta-analysis of the osteoporosis acid-ash diet hypothesis
    Tanis R Fenton
    Clinical Nutrition, Alberta Health Services, Calgary, AB, Canada
    Nutr J 8:41. 2009
    ....
  5. pmc A randomized controlled trial of vitamin D dosing strategies after acute hip fracture: no advantage of loading doses over daily supplementation
    Alexandra Papaioannou
    McMaster University, HHSC, St Peter s Hospital Juravinski Research Centre, 88 Maplewood Avenue Hamilton, ON L8M 1W9, Canada
    BMC Musculoskelet Disord 12:135. 2011
    ..The primary aim of our study was to examine whether large loading doses in addition to daily vitamin D offered any advantage over a simple daily low-dose vitamin D regimen for increasing vitamin D levels...
  6. pmc Treatment of osteoporosis in an older home care population
    Shelly A Vik
    Department of Community Health Sciences University of Calgary, Calgary AB, Canada
    BMC Musculoskelet Disord 6:7. 2005
    ..We assessed osteoporosis treatment coverage in older home care clients with a diagnosis of osteoporosis and/or prevalent fracture...
  7. pmc Low urine pH and acid excretion do not predict bone fractures or the loss of bone mineral density: a prospective cohort study
    Tanis R Fenton
    Department of Community Health Sciences, Faculty of Medicine, University of Calgary TRW Building, 3rd Floor, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6, Canada
    BMC Musculoskelet Disord 11:88. 2010
    ..8x phosphate + organic acids] minus [sodium + potassium + 2x calcium + 2x magnesium mEq] in fasting morning urine predict: a) fragility fractures; and b) five-year change of bone mineral density (BMD) in adults...
  8. pmc Dietary patterns in Canadian men and women ages 25 and older: relationship to demographics, body mass index, and bone mineral density
    Lisa Langsetmo
    Dalla Lana School of Public Health, University of Toronto, 155 College St, Toronto, ON, Canada
    BMC Musculoskelet Disord 11:20. 2010
    ....
  9. pmc Evaluation of easily measured risk factors in the prediction of osteoporotic fractures
    Robert Bensen
    Medical Science, McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 6:47. 2005
    ..As few premonitory symptoms for fracture exist, it is of critical importance that physicians effectively and efficiently identify individuals at increased fracture risk...
  10. ncbi request reprint Vitamin D insufficiency in North America
    David A Hanley
    Division of Endocrinology and Metabolism, Departments of Medicine and Oncology, University of Calgary Faculty of Medicine, Calgary, Alberta, Canada
    J Nutr 135:332-7. 2005
    ..The response to vitamin D supplementation in clinical trials suggests current recommendations for dietary intake of this vitamin are too low and that a higher adequate intake should be recommended...
  11. ncbi request reprint Etridronate therapy in the treatment and prevention of osteoporosis
    D A Hanley
    Department of Medicine, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Clin Densitom 3:79-95. 2000
    ..Increases in bone density at the spine and hip are not as pronounced as with some other bisphosphonates, particularly alendronate, but no direct clinical comparison trials of significant size or duration have been undertaken...
  12. ncbi request reprint Associations among disease conditions, bone mineral density, and prevalent vertebral deformities in men and women 50 years of age and older: cross-sectional results from the Canadian Multicentre Osteoporosis Study
    D A Hanley
    Department of Medicine, University of Calgary Calgary, Alberta, Canada
    J Bone Miner Res 18:784-90. 2003
    ..The importance of these associations for osteoporosis case finding and management require further and prospective studies...
  13. doi request reprint Cost-effectiveness of a multifaceted intervention to improve quality of osteoporosis care after wrist fracture
    S R Majumdar
    Department of Medicine, University of Alberta, Edmonton, AB, Canada
    Osteoporos Int 22:1799-808. 2011
    ..An economic analysis of the trial now demonstrates that the intervention tested "dominates" usual care: over a lifetime horizon, it reduces fracture, increases quality-adjusted life years, and saves the healthcare system money...
  14. doi request reprint Nurse case-manager vs multifaceted intervention to improve quality of osteoporosis care after wrist fracture: randomized controlled pilot study
    S R Majumdar
    Department of Medicine, University of Alberta, 8440 112th Street, Edmonton, Alberta, T6G 2B7, Canada
    Osteoporos Int 22:223-30. 2011
    ....
  15. ncbi request reprint The association between osteoporotic fractures and health-related quality of life as measured by the Health Utilities Index in the Canadian Multicentre Osteoporosis Study (CaMos)
    J D Adachi
    Department of Medicine, St Joseph s Hospital, McMaster University, Charlton Avenue East, Suite 501, L8 N 1Y2 Hamilton, Ontario, Canada
    Osteoporos Int 14:895-904. 2003
    ..06; 95% CI: -0.11, -0.00) for women, and rib fractures (-0.06; 95% CI: -0.12, -0.00) for men. In conclusion, this study demonstrates a negative association between osteoporotic fractures and quality of life in both women and men...
  16. doi request reprint Women with previous fragility fractures can be classified based on bone microarchitecture and finite element analysis measured with HR-pQCT
    K K Nishiyama
    Schulich School of Engineering, University of Calgary, Calgary, Canada
    Osteoporos Int 24:1733-40. 2013
    ..The HR-pQCT measurements outperformed dual energy x-ray absorptiometry (DXA) at classifying forearm fractures and fractures at other skeletal sites...
  17. ncbi request reprint Bisphosphonates reduce bone mineral loss at ligament entheses after joint injury
    M R Doschak
    McCaig Centre for Joint Injury and Arthritis Research, Biomedical Peptide Conjunction Laboratory, Department of Chemical and Materials Engineering, University of Calgary, Calgary, AB, Canada
    Osteoarthritis Cartilage 13:790-7. 2005
    ..To examine the effects of anterior cruciate ligament (ACL) insufficiency, and subsequent bisphosphonate (BP) antiresorptive therapy, on the bone mineral interface at the enthesis of remaining ligamentous restraints...
  18. doi request reprint Construction and validation of a simplified fracture risk assessment tool for Canadian women and men: results from the CaMos and Manitoba cohorts
    W D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, MB, Canada
    Osteoporos Int 22:1873-83. 2011
    ..A procedure for creating a simplified version of fracture risk assessment tool (FRAX®) is described. Calibration, fracture prediction, and concordance were compared with the full FRAX tool using two large, complementary Canadian datasets...
  19. ncbi request reprint What is the number of older Canadians needed to screen by measurement of bone density to detect an undiagnosed case of osteoporosis? a population-based study from CaMos
    Anna M Sawka
    Department of Medicine, Division of Endocrinology, University of Toronto, Toronto, Ontario, Canada
    J Clin Densitom 9:413-8. 2006
    ..9%, 97.0%; 68 of 73) were not aware of it. Thus, the minimum NNS by BMD testing to detect one previously undiagnosed case of osteoporosis in Canada is: 6 women aged >or=65 yr, 13 men aged >or=65 yr, and 10 men aged >or=70 yr...
  20. doi request reprint Effect of tumor necrosis factor alpha inhibition on bone density and turnover markers in patients with rheumatoid arthritis and spondyloarthropathy
    Cheryl Barnabe
    Division of Rheumatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Semin Arthritis Rheum 39:116-22. 2009
    ....
  21. ncbi request reprint IGF-I and testosterone levels as predictors of bone mineral density in healthy, community-dwelling men
    Diana Rucker
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Clin Endocrinol (Oxf) 60:491-9. 2004
    ..In this cross-sectional study, the relation between serum IGF-I and gonadal hormones with bone mineral density (BMD) was examined in community-dwelling men...
  22. ncbi request reprint Persistence, reproducibility, and cost-effectiveness of an intervention to improve the quality of osteoporosis care after a fracture of the wrist: results of a controlled trial
    S R Majumdar
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Osteoporos Int 18:261-70. 2007
    ..Our objective was to examine longer-term outcomes, reproducibility, and cost-effectiveness of this intervention...
  23. ncbi request reprint Prevalence of IgA-antiendomysial antibody in asymptomatic low bone mineral density
    K J Mather
    Division of Gastroenterology, University of Calgary, Alberta, Canada
    Am J Gastroenterol 96:120-5. 2001
    ..Without an increase over the background prevalence, the high cost of EMA testing argues against routine use of this test for screening of this population...
  24. ncbi request reprint Changes to osteoporosis prevalence according to method of risk assessment
    J Brent Richards
    Department of Medicine, McGill University, Montreal, Quebec, Canada
    J Bone Miner Res 22:228-34. 2007
    ....
  25. ncbi request reprint Diagnosis and treatment of Paget's disease of bone
    Robert G Josse
    Division of Endocrinology and Metabolism, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario
    Clin Invest Med 30:E210-23. 2007
    ..The Panel recommends treating PDB with bisphosphonates that have demonstrated superior efficacy and remission rates...
  26. doi request reprint Changes in trabecular and cortical bone microarchitecture at peripheral sites associated with 18 months of teriparatide therapy in postmenopausal women with osteoporosis
    H M Macdonald
    Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, 2500 University Drive, N W, Calgary, AB, T2N 1N4, Canada
    Osteoporos Int 22:357-62. 2011
    ..Despite treatment-associated declines in total and cortical BMD, trabecular thinning and reduced trabecular bone volume, bone strength did not change significantly from baseline...
  27. ncbi request reprint Antiresorptive therapy conserves some periarticular bone and ligament mechanical properties after anterior cruciate ligament disruption in the rabbit knee
    M R Doschak
    Department of Surgery, University of Calgary, 3330 Hospital Drive N W, Calgary, Alberta, Canada T2N 4N1
    J Orthop Res 22:942-8. 2004
    ..Thus, administering BP immediately after ACL loss conserved some periarticular bone and MCL-complex properties in an early OA model...
  28. ncbi request reprint Incidental vertebral fractures discovered with chest radiography in the emergency department: prevalence, recognition, and osteoporosis management in a cohort of elderly patients
    Sumit R Majumdar
    Division of General Internal Medicine, Department of Medicine, Room 2E3 07 Walter Mackenzie Health Sciences Centre, Uinversity of Alberta Hospital, 8440 112th St, Edmonton, Alberta, Canada T6G 2B7
    Arch Intern Med 165:905-9. 2005
    ..Our objectives were to determine the utility of chest radiographs for detecting previously unrecognized vertebral fractures; document rates of recognition; and evaluate osteoporosis treatments...
  29. ncbi request reprint Use of a case manager to improve osteoporosis treatment after hip fracture: results of a randomized controlled trial
    Sumit R Majumdar
    Department of Medicine, 362 Heritage Medical Research Center, University of Alberta, Edmonton AB T6G 2S2, Canada
    Arch Intern Med 167:2110-5. 2007
    ..The case manager educated patients, arranged bone mineral density tests, provided prescriptions, and communicated with primary care physicians. The intervention was compared with usual care in a randomized controlled trial...
  30. ncbi request reprint Meta-analysis of the quantity of calcium excretion associated with the net acid excretion of the modern diet under the acid-ash diet hypothesis
    Tanis R Fenton
    Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada
    Am J Clin Nutr 88:1159-66. 2008
    ..A systematic approach has not been used to summarize the findings of the numerous studies about the hypothesis...
  31. ncbi request reprint A controlled trial to increase detection and treatment of osteoporosis in older patients with a wrist fracture
    Sumit R Majumdar
    Department of Medicine, University of Alberta, 2E3 07 Walter Mackenzie Health Sciences Centre, University of Alberta Hospital, 8440 112th Street, Edmonton, Alberta T6G 2B7, Canada
    Ann Intern Med 141:366-73. 2004
    ..Despite the high risk for future fractures and the availability of effective treatments, fewer than 10% to 20% of patients who sustain a fragility fracture are tested or treated for osteoporosis...
  32. ncbi request reprint Factors associated with pharmacologic treatment of osteoporosis in an older home care population
    Shelly A Vik
    Department of Community Health Sciences, Faculty of Medicine, University of Calgary, 3330 Hospital Drive N W, Calgary, AB, Canada T2N 4N1
    J Gerontol A Biol Sci Med Sci 62:872-8. 2007
    ..Our objective was to examine which sociodemographic, clinical, and functional characteristics are associated with pharmacotherapy for osteoporosis among community-based seniors...
  33. doi request reprint Facilitated bone mineral density testing versus hospital-based case management to improve osteoporosis treatment for hip fracture patients: additional results from a randomized trial
    Donald W Morrish
    University of Alberta, Edmonton, Alberta, Canada
    Arthritis Rheum 61:209-15. 2009
    ..The second phase of the randomized trial compared a less intensive intervention, facilitated bone mineral density (BMD) testing, with usual care and the case manager intervention...
  34. ncbi request reprint Prescriptions for vitamin D among patients taking antiresorptive agents in Canada
    David A Hanley
    Department of Medicine, Faculty of Medicine, University of Calgary, Alberta, Canada
    Curr Med Res Opin 23:1473-80. 2007
    ..Such information is important because vitamin D is indicated in patients with osteoporosis, including those receiving bisphosphonates, and there is evidence of inadequate use by these patients...
  35. doi request reprint Meta-analysis of the effect of the acid-ash hypothesis of osteoporosis on calcium balance
    Tanis R Fenton
    Alberta Health Services, Calgary, Alberta, Canada
    J Bone Miner Res 24:1835-40. 2009
    ..Changes of urine calcium do not accurately represent calcium balance. Promotion of the "alkaline diet" to prevent calcium loss is not justified...
  36. doi request reprint Assessing fracture risk and effects of osteoporosis drugs: bone mineral density and beyond
    K Shawn Davison
    Department of Medicine, Division of Rheumatology and Immunology, Laval University, Quebec, PQ, Canada
    Am J Med 122:992-7. 2009
    ..This article discusses the assessment of fracture risk in clinical practice, reviews currently and soon-available bone measurement tools, and details the impacts of osteoporosis therapies on fracture risk...
  37. ncbi request reprint Bone strength: the whole is greater than the sum of its parts
    K Shawn Davison
    Clinical Research Scientist, Department of Medicine, Laval University, Sainte Foy, Quebec, Canada
    Semin Arthritis Rheum 36:22-31. 2006
    ..To summarize the current knowledge regarding the various determinants of bone strength...
  38. ncbi request reprint Adherence to bisphosphonates and hormone replacement therapy in a tertiary care setting of patients in the CANDOO database
    Alexandra Papaioannou
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 14:808-13. 2003
    ..In conclusion, alendronate users were more likely to discontinue therapy than etidronate users over the follow-up period. Potential barriers to long-term patient adherence to osteoporosis therapies need to be evaluated...
  39. ncbi request reprint Osteoporosis in men: epidemiology, diagnosis, prevention, and treatment
    Wojciech P Olszynski
    Department of Medicine, University of Saskatchewan, Saskatoon Osteoporosis Centre, Saskatoon, Saskatchewan, Canada
    Clin Ther 26:15-28. 2004
    ..Osteoporosis and fragility fractures in men account for substantial health care expenditures and decreased quality of life...
  40. ncbi request reprint The effects of antifracture therapies on the components of bone strength: assessment of fracture risk today and in the future
    K Shawn Davison
    Clinical Research Scientist, Department of Medicine, Laval University, Sainte Foy, Quebec, Canada
    Semin Arthritis Rheum 36:10-21. 2006
    ..To summarize the current knowledge regarding the impact of the most common antifracture medications on the various determinants of bone strength...
  41. ncbi request reprint Risk factors associated with incident clinical vertebral and nonvertebral fractures in postmenopausal women: the Canadian Multicentre Osteoporosis Study (CaMos)
    Alexandra Papaioannou
    Department of Medicine, St Joseph s Hospital, McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 16:568-78. 2005
    ..Furthermore, various anthropometric measures, disease conditions, and medications are associated with a new fracture. Identifying postmenopausal women at risk is important given that fracture prevention therapies are now available...
  42. ncbi request reprint Postmenopausal women with osteopenia have higher cortical porosity and thinner cortices at the distal radius and tibia than women with normal aBMD: an in vivo HR-pQCT study
    Kyle K Nishiyama
    Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, Canada
    J Bone Miner Res 25:882-90. 2010
    ..1% to 8.1%, p < .001) cortices than normal postmenopausal women. Our method offers promise as a valuable tool to measure Ct.Po and Ct.Th in vivo and investigate associations among cortical bone structure, age, and disease status...
  43. doi request reprint Trends in hip fracture rates in Canada
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    JAMA 302:883-9. 2009
    ..Hip fractures are a public health concern because they are associated with significant morbidity, excess mortality, and the majority of the costs directly attributable to osteoporosis...
  44. ncbi request reprint Determinants of health-related quality of life in women with vertebral fractures
    Alexandra Papaioannou
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 17:355-63. 2006
    ..We demonstrated that several modifiable factors influence HRQL in patients with vertebral fractures, and physicians should be aware of these and other markers of reduced HRQL to enhance patient care...
  45. ncbi request reprint Assessing compliance, acceptance, and tolerability of teriparatide in patients with osteoporosis who fractured while on antiresorptive treatment or were intolerant to previous antiresorptive treatment: an 18-month, multicenter, open-label, prospective stu
    Jonathan D Adachi
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Clin Ther 29:2055-67. 2007
    ..It has been found to significantly reduce vertebral fractures by 65%, and nonvertebral fragility fractures by 53% in treatment-naive postmenopausal women who have previously suffered a vertebral fracture...
  46. pmc Change in bone mineral density as a function of age in women and men and association with the use of antiresorptive agents
    Claudie Berger
    CaMos Methods Centre, McGill University, Montreal, Que
    CMAJ 178:1660-8. 2008
    ..We sought to estimate the average rate of change in bone mineral density as a function of age among Canadians aged 25-85, stratified by sex and use of antiresorptive agents...
  47. pmc Vitamin D insufficiency in a population of healthy western Canadians
    Diana Rucker
    Department of Medical Science, University of Calgary, Alta
    CMAJ 166:1517-24. 2002
    ....
  48. ncbi request reprint Effect of recombinant human parathyroid hormone (1-84) on vertebral fracture and bone mineral density in postmenopausal women with osteoporosis: a randomized trial
    Susan L Greenspan
    University of Pittsburgh, Osteoporosis Prevention and Treatment Center, Pittsburgh, Pennsylvania 15213, USA
    Ann Intern Med 146:326-39. 2007
    ..Recombinant human parathyroid hormone (1-84) (PTH) increases bone mass and strength and improves bone quality by stimulating new bone formation...
  49. pmc Multifaceted intervention to improve diagnosis and treatment of osteoporosis in patients with recent wrist fracture: a randomized controlled trial
    Sumit R Majumdar
    Department of Medicine, University of Alberta, Edmonton, Alta
    CMAJ 178:569-75. 2008
    ....
  50. ncbi request reprint Are there differences between men and women prescribed bisphosphonate therapy in canadian subspecialty osteoporosis practices?
    Anna M Sawka
    McMaster University, St Joseph s Healthcare, Centre for Evaluation of Medicines, Hamilton, Ontario, Canada
    J Rheumatol 31:1993-5. 2004
    ..To determine if there are differences between men and women referred for treatment of osteoporosis in Canada...
  51. ncbi request reprint The canadian health claim for calcium, vitamin d and osteoporosis
    Mary R L'abbé
    Bureau of Nutritional Sciences, Health Canada, Ottawa, Canada
    J Am Coll Nutr 23:303-8. 2004
    ..The compositional criteria for foods bearing this claim are that the food must provide at least 200 mg calcium per serving and that the phosphorus content (excluding that provided by phytate) must be less than the calcium content...
  52. ncbi request reprint Standards and guidelines for technologists performing central dual-energy X-ray absorptiometry
    Aliya A Khan
    Division of Endocrinology, McMaster University, Hamilton, Ontario, Canada
    J Clin Densitom 10:189-95. 2007
  53. ncbi request reprint Standards and guidelines for performing central dual-energy x-ray absorptiometry in premenopausal women, men, and children
    Aliya A Khan
    Divisions of Endocrinology and Geriatrics, McMaster University, Hamilton, ON, Canada
    J Clin Densitom 7:51-64. 2004
    ..Previously, this group addressed the performance of densitometry in postmenopausal women. This report addresses the use of densitometry in men, premenopausal women, and children with a focus on dual-energy X-ray absorptiometry...
  54. ncbi request reprint Efficacy and safety of human parathyroid hormone-(1-84) in increasing bone mineral density in postmenopausal osteoporosis
    Anthony B Hodsman
    Department of Medicine, Lawson Health Research Institute, University of Western Ontario, London, Ontario, Canada N6A 4V2
    J Clin Endocrinol Metab 88:5212-20. 2003
    ..Dose-related incidences of transient hypercalcemia occurred, but only one patient (100-microg group) was withdrawn because of repeated hypercalcemia. Thus, full-length PTH was efficacious and safe over 12 months...
  55. ncbi request reprint What predicts early fracture or bone loss on bisphosphonate therapy?
    Anna M Sawka
    McMaster University, Hamilton, ON, CA
    J Clin Densitom 6:315-22. 2003
    ..13, 0.62, p = 0.002). In conclusion, early fracture on bisphosphonate therapy is most strongly predicted by a previous history of fracture and early bone loss is most strongly predicted by the potency of the prescribed bisphosphonate...
  56. ncbi request reprint Stability of normative data for the SF-36: results of a three-year prospective study in middle-aged Canadians
    Wilma M Hopman
    Clinical Research Centre, Kingston General Hospital and Department of Community Health and Epidemiology, Queen s University, Kingston, ON
    Can J Public Health 95:387-91. 2004
    ..This paper assesses mean changes in SF-36 scores over a 3-year period in men and women between the ages of 40 and 59 years at baseline...
  57. ncbi request reprint Do hip protectors decrease the risk of hip fracture in institutional and community-dwelling elderly? A systematic review and meta-analysis of randomized controlled trials
    Anna M Sawka
    Division of Endocrinology and Department of Medicine, St Joseph s Healthcare and McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 16:1461-74. 2005
    ..Thus, there is little evidence to support the use of hip protectors outside the nursing home setting. The potential benefit of hip protectors in reducing hip fractures in nursing home residents requires further confirmation...
  58. ncbi request reprint A systematic review of the effect of alendronate on bone mineral density in men
    Anna M Sawka
    McMaster University, Hamilton, Ontario, Canada L8N 1Y2
    J Clin Densitom 8:7-13. 2005
    ..We conclude that 10 mg of oral daily alendronate is significantly associated with increase in BMD at the lumbar spine and hip in men over 2-3 yr and that these changes are similar to those previously observed in postmenopausal women...
  59. ncbi request reprint Standards for performing DXA in individuals with secondary causes of osteoporosis
    Aliya A Khan
    Division of Endocrinology, McMaster University, Hamilton, Ontario, Canada, and Hanover General Hospital, PA, USA
    J Clin Densitom 9:47-57. 2006
    ..Dual-energy X-ray absorptiometry is a valuable tool in assessing skeletal health in individuals with secondary causes of osteoporosis...
  60. ncbi request reprint Parathyroid hormone and teriparatide for the treatment of osteoporosis: a review of the evidence and suggested guidelines for its use
    Anthony B Hodsman
    University of Western Ontario, St Joseph s Health Care, Room 2F 15, 268, Grosvenor Street, London, Ontario N6A 4V2, Canada
    Endocr Rev 26:688-703. 2005
    ..At present, concurrent therapy with antiresorptive therapy, particularly bisphosphonates, should be avoided, although sequential therapy with such agents may consolidate the beneficial effects upon the skeleton after PTH is discontinued...
  61. ncbi request reprint The natural progression of health-related quality of life: results of a five-year prospective study of SF-36 scores in a normative population
    Wilma M Hopman
    Clinical Research Centre, Kingston General Hospital and Department of Community Health and Epidemiology, Queen s University, Kingston, Ontario, K7L 2V7, Canada
    Qual Life Res 15:527-36. 2006
    ..Such norms are important to establish, because the effect of any intervention may be confounded by changes due to the natural progression of HRQOL over time...
  62. ncbi request reprint Simple computer model for calculating and reporting 5-year osteoporotic fracture risk in postmenopausal women
    Bruce Ettinger
    Division of Research, Kaiser Permanente Medical Care Program, Oakland, California, USA
    J Womens Health (Larchmt) 14:159-71. 2005
    ..To devise, validate, and test a software model that improves how clinicians calculate individual risk for osteoporotic fracture and expected treatment benefit...
  63. ncbi request reprint Are oral bisphosphonates effective in improving lumbar bone mineral density in breast cancer survivors with osteopenia or osteoporosis?
    Anna M Sawka
    Department of Medicine, St Joseph s Healthcare and McMaster University, Hamilton ON
    J Obstet Gynaecol Can 27:759-64. 2005
    ....
  64. ncbi request reprint Calcium, dairy products, and bone health in children and young adults: an inaccurate conclusion
    Tanis R Fenton
    Pediatrics 117:259-60; author reply 260-1. 2006
  65. ncbi request reprint Is there regional variation in the SF-36 scores of Canadian adults?
    Wilma M Hopman
    MacKenzie Health Services Research Group, Department of Community Health and Epidemiology, 3rd Floor, Abramsky Hall, Queen s University, Kingston, ON K7L 3N6
    Can J Public Health 93:233-7. 2002
    ..We therefore examined the SF-36 data from nine Canadian centres for evidence of systematic differences...