Nicola Haines

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi Dystroglycan and protein O-mannosyltransferases 1 and 2 are required to maintain integrity of Drosophila larval muscles
    Nicola Haines
    Department of Biology, University of Toronto, Mississauga, ON, Canada L5L 1C6
    Mol Biol Cell 18:4721-30. 2007
  2. ncbi Functional roles for beta1,4-N-acetlygalactosaminyltransferase-A in Drosophila larval neurons and muscles
    Nicola Haines
    Department of Biology, University of Toronto, Mississauga, Ontario L5L 1C6, Canada
    Genetics 175:671-9. 2007
  3. ncbi Synaptic vesicle mobility and presynaptic F-actin are disrupted in a N-ethylmaleimide-sensitive factor allele of Drosophila
    Paula Nunes
    Department of Biology and Computer Science, University of Toronto, Mississauga, Ontario, Canada
    Mol Biol Cell 17:4709-19. 2006
  4. ncbi Functional analysis of Drosophila beta1,4-N-acetlygalactosaminyltransferases
    Nicola Haines
    Howard Hughes Medical Institute, Waksman Institute, and Department of Molecular Biology and Biochemistry, Rutgers The State University of New Jersey, Piscataway NJ 08854, USA
    Glycobiology 15:335-46. 2005
  5. ncbi In vitro reconstitution of the modulation of Drosophila Notch-ligand binding by Fringe
    Aiguo Xu
    Howard Hughes Medical Institute, Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA
    J Biol Chem 282:35153-62. 2007
  6. ncbi Identification of a Drosophila gene encoding xylosylprotein beta4-galactosyltransferase that is essential for the synthesis of glycosaminoglycans and for morphogenesis
    Yoko Nakamura
    Department of Biochemistry II, Nagoya University School of Medicine, 65 Tsurumai, Showa Ku, Nagoya 466 0065, Japan
    J Biol Chem 277:46280-8. 2002
  7. ncbi Glycosylation regulates Notch signalling
    Nicola Haines
    Howard Hughes Medical Institute, Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Nat Rev Mol Cell Biol 4:786-97. 2003
  8. ncbi Distinct contributions of beta 4GalNAcTA and beta 4GalNAcTB to Drosophila glycosphingolipid biosynthesis
    Anita Stolz
    Zelluläre Chemie, Zentrum Biochemie, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30625, Hannover, Germany
    Glycoconj J 25:167-75. 2008

Collaborators

Detail Information

Publications8

  1. ncbi Dystroglycan and protein O-mannosyltransferases 1 and 2 are required to maintain integrity of Drosophila larval muscles
    Nicola Haines
    Department of Biology, University of Toronto, Mississauga, ON, Canada L5L 1C6
    Mol Biol Cell 18:4721-30. 2007
    ..This study opens the possibility of using Drosophila to investigate muscular dystrophy...
  2. ncbi Functional roles for beta1,4-N-acetlygalactosaminyltransferase-A in Drosophila larval neurons and muscles
    Nicola Haines
    Department of Biology, University of Toronto, Mississauga, Ontario L5L 1C6, Canada
    Genetics 175:671-9. 2007
    ..Altogether, these results suggest that beta4GalNAcTA has at least three distinct functional roles...
  3. ncbi Synaptic vesicle mobility and presynaptic F-actin are disrupted in a N-ethylmaleimide-sensitive factor allele of Drosophila
    Paula Nunes
    Department of Biology and Computer Science, University of Toronto, Mississauga, Ontario, Canada
    Mol Biol Cell 17:4709-19. 2006
    ..Our data are consistent with a model in which actin filaments promote vesicle mobility and suggest that NSF participates in establishing or maintaining this population of actin...
  4. ncbi Functional analysis of Drosophila beta1,4-N-acetlygalactosaminyltransferases
    Nicola Haines
    Howard Hughes Medical Institute, Waksman Institute, and Department of Molecular Biology and Biochemistry, Rutgers The State University of New Jersey, Piscataway NJ 08854, USA
    Glycobiology 15:335-46. 2005
    ..Thus Drosophila homologs of the mammalian beta4GalT family are essential for neuromuscular physiology or development but are not otherwise required for viability, fertility, or external morphology...
  5. ncbi In vitro reconstitution of the modulation of Drosophila Notch-ligand binding by Fringe
    Aiguo Xu
    Howard Hughes Medical Institute, Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA
    J Biol Chem 282:35153-62. 2007
    ....
  6. ncbi Identification of a Drosophila gene encoding xylosylprotein beta4-galactosyltransferase that is essential for the synthesis of glycosaminoglycans and for morphogenesis
    Yoko Nakamura
    Department of Biochemistry II, Nagoya University School of Medicine, 65 Tsurumai, Showa Ku, Nagoya 466 0065, Japan
    J Biol Chem 277:46280-8. 2002
    ..Our results demonstrate that Drosophila beta4GalT7 has the in vitro and in vivo properties predicted for an ortholog of human beta4GalT7 and is essential for normal animal development through its role in proteoglycan biosynthesis...
  7. ncbi Glycosylation regulates Notch signalling
    Nicola Haines
    Howard Hughes Medical Institute, Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Nat Rev Mol Cell Biol 4:786-97. 2003
    ....
  8. ncbi Distinct contributions of beta 4GalNAcTA and beta 4GalNAcTB to Drosophila glycosphingolipid biosynthesis
    Anita Stolz
    Zelluläre Chemie, Zentrum Biochemie, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30625, Hannover, Germany
    Glycoconj J 25:167-75. 2008
    ....