Urs O Hafeli

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. doi request reprint Cell uptake and in vitro toxicity of magnetic nanoparticles suitable for drug delivery
    Urs O Hafeli
    Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC V6T 1Z3, Canada
    Mol Pharm 6:1417-28. 2009
  2. doi request reprint Lung perfusion imaging with monosized biodegradable microspheres
    Urs O Hafeli
    Faculty of Pharmaceutical Sciences and Department of Mechanical Engineering, The University of British Columbia, Vancouver, British Columbia, Canada
    Biomacromolecules 11:561-7. 2010
  3. doi request reprint Hyperbranched polyglycerols as trimodal imaging agents: design, biocompatibility, and tumor uptake
    Katayoun Saatchi
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
    Bioconjug Chem 23:372-81. 2012
  4. doi request reprint One to chelate them all: investigation of a versatile, bifunctional chelator for 64Cu, 99mTc, Re and Co
    Eszter Boros
    Medicinal Inorganic Chemistry Group, Department of Chemistry, The University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada
    Dalton Trans 40:6253-9. 2011
  5. doi request reprint Design, synthesis, and imaging of small amphiphilic rhenium and (99m)technetium tricarbonyl complexes
    Eszter Boros
    Department of Chemistry, University of British Columbia, Vancouver, British Columbia V6T 1Z1, Canada
    Bioconjug Chem 20:1002-9. 2009
  6. doi request reprint Effects of chemical and physical parameters in the generation of microspheres by hydrodynamic flow focusing
    Thomas Schneider
    Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, BC, Canada
    Colloids Surf B Biointerfaces 87:361-8. 2011
  7. doi request reprint Uniform polymer microspheres: monodispersity criteria, methods of formation and applications
    José Carlos De La Vega
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Nanomedicine (Lond) 8:265-85. 2013
  8. doi request reprint Long-circulating non-toxic blood pool imaging agent based on hyperbranched polyglycerols
    Katayoun Saatchi
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
    Int J Pharm 422:418-27. 2012
  9. doi request reprint Radiolabeling of fab and f(ab')2 antibody fragments with 99mTc(I) tricarbonyl core using a new bifunctional tridentate ligand
    Ripen Misri
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
    Nucl Med Commun 32:324-9. 2011
  10. doi request reprint Radiolabeling of biodegradable polymeric microspheres with [99mTc(CO)3]+ and in vivo biodistribution evaluation using MicroSPECT/CT imaging
    Katayoun Saatchi
    Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC V6T 1Z3, Canada
    Bioconjug Chem 20:1209-17. 2009

Collaborators

Detail Information

Publications17

  1. doi request reprint Cell uptake and in vitro toxicity of magnetic nanoparticles suitable for drug delivery
    Urs O Hafeli
    Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC V6T 1Z3, Canada
    Mol Pharm 6:1417-28. 2009
    ..It is concluded that magnetite nanoparticles coated with triblock copolymers containing PEO tail lengths of above 2 kDa are biocompatible and appropriate for in vivo application...
  2. doi request reprint Lung perfusion imaging with monosized biodegradable microspheres
    Urs O Hafeli
    Faculty of Pharmaceutical Sciences and Department of Mechanical Engineering, The University of British Columbia, Vancouver, British Columbia, Canada
    Biomacromolecules 11:561-7. 2010
    ..Other sizes of these highly uniform microspheres have the potential to improve diagnostic and therapeutic approaches in diverse areas of medicine...
  3. doi request reprint Hyperbranched polyglycerols as trimodal imaging agents: design, biocompatibility, and tumor uptake
    Katayoun Saatchi
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
    Bioconjug Chem 23:372-81. 2012
    ....
  4. doi request reprint One to chelate them all: investigation of a versatile, bifunctional chelator for 64Cu, 99mTc, Re and Co
    Eszter Boros
    Medicinal Inorganic Chemistry Group, Department of Chemistry, The University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada
    Dalton Trans 40:6253-9. 2011
    ..Besides coordination chemistry with stable isotopes, we also present labelling data with (64)Cu and (99m)Tc, as well as in vitro stability studies...
  5. doi request reprint Design, synthesis, and imaging of small amphiphilic rhenium and (99m)technetium tricarbonyl complexes
    Eszter Boros
    Department of Chemistry, University of British Columbia, Vancouver, British Columbia V6T 1Z1, Canada
    Bioconjug Chem 20:1002-9. 2009
    ..Distinct localization of small amphiphilic molecules in in vivo systems depends on the charge of the polar moiety and was studied via biodistribution (4 h) and imaging (15 min, 1, 2, and 4 h) in female C57Bl/6 mice...
  6. doi request reprint Effects of chemical and physical parameters in the generation of microspheres by hydrodynamic flow focusing
    Thomas Schneider
    Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, BC, Canada
    Colloids Surf B Biointerfaces 87:361-8. 2011
    ..Applications for microspheres made with this method can be found in the medical, pharmaceutical and technical fields...
  7. doi request reprint Uniform polymer microspheres: monodispersity criteria, methods of formation and applications
    José Carlos De La Vega
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Nanomedicine (Lond) 8:265-85. 2013
    ....
  8. doi request reprint Long-circulating non-toxic blood pool imaging agent based on hyperbranched polyglycerols
    Katayoun Saatchi
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
    Int J Pharm 422:418-27. 2012
    ....
  9. doi request reprint Radiolabeling of fab and f(ab')2 antibody fragments with 99mTc(I) tricarbonyl core using a new bifunctional tridentate ligand
    Ripen Misri
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
    Nucl Med Commun 32:324-9. 2011
    ..From our studies, it can be concluded that the newly synthesized N-(ortho-phenol)-histidine chelator is a promising candidate for [Tc(CO)3] labeling of biomolecules and for developing other novel Tc radiopharmaceuticals...
  10. doi request reprint Radiolabeling of biodegradable polymeric microspheres with [99mTc(CO)3]+ and in vivo biodistribution evaluation using MicroSPECT/CT imaging
    Katayoun Saatchi
    Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC V6T 1Z3, Canada
    Bioconjug Chem 20:1209-17. 2009
    ..Similarly, other sizes of the same microspheres will allow imaging of lung perfusion, bone marrow, lymph and inflammation scintigraphy, and radioembolization therapy...
  11. doi request reprint Focused magnetic stem cell targeting to the retina using superparamagnetic iron oxide nanoparticles
    Anat Yanai
    Department of Ophthalmology and Visual Science, Faculty of Medicine, University of British Columbia, Vancouver, Canada
    Cell Transplant 21:1137-48. 2012
    ....
  12. doi request reprint Nanoprobes for hybrid SPECT/MR molecular imaging
    Ripen Misri
    Experimental Therapeutics, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, BC V5Z 1L3, Canada
    Nanomedicine (Lond) 7:719-33. 2012
    ..In this review, we present some of the latest developments in the domain of SPECT/MR hybrid imaging, particularly focusing on multimodal nanoprobes...
  13. ncbi request reprint Evaluation of (111)In labeled antibodies for SPECT imaging of mesothelin expressing tumors
    Ripen Misri
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Nucl Med Biol 38:885-96. 2011
    ..In the present study, we evaluate (111)In labeled antimesothelin antibodies as an imaging bioprobe for the SPECT imaging of mesothelin-expressing tumors...
  14. doi request reprint Development and evaluation of a dual-modality (MRI/SPECT) molecular imaging bioprobe
    Ripen Misri
    Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
    Nanomedicine 8:1007-16. 2012
    ....
  15. doi request reprint In vivo evaluation of a microneedle-based miniature syringe for intradermal drug delivery
    Urs O Hafeli
    Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
    Biomed Microdevices 11:943-50. 2009
    ..Such microneedle devices could be used for the intradermal delivery of vaccination agents or for the systemic delivery of highly effective drugs...
  16. doi request reprint Use of hydrodynamic flow focusing for the generation of biodegradable camptothecin-loaded polymer microspheres
    Thomas Schneider
    Division of Pharmaceutics and Biopharmaceutics, Faculty of Pharmaceutical Sciences, The University of British Columbia, 2146 East Mall, Vancouver, BC V6T1Z3, Canada
    J Pharm Sci 97:4943-54. 2008
    ....
  17. ncbi request reprint Fibrin glue system for adjuvant brachytherapy of brain tumors with 188Re and 186Re-labeled microspheres
    Urs O Hafeli
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
    Eur J Pharm Biopharm 65:282-8. 2007
    ....