Research Topics
| Haissam HaddadSummaryAffiliation: University of Ottawa Heart Institute Country: Canada Publications
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Detail Information
Publications
Recent advances in the management of chronic heart failureHaissam Haddad
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Curr Opin Cardiol 27:161-8. 2012..This review will provide an overview of the recent advances in the management of chronic heart failure, with special focus on major publications in the past 2 years, 2010-2011...
Relation between right ventricular function and increased right ventricular [18F]fluorodeoxyglucose accumulation in patients with heart failureLisa M Mielniczuk
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada
Circ Cardiovasc Imaging 4:59-66. 2011....
Relationship between natriuretic peptides and inflammation: proteomic evidence obtained during acute cellular cardiac allograft rejection in humansYael F Meirovich
Cardiovascular Endocrinology Laboratory, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
J Heart Lung Transplant 27:31-7. 2008..In vitro, the pro-inflammatory cytokines interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) produced a selective increase of BNP gene expression and secretion. Other pro-inflammatory cytokines had no such effects...
Worsening renal function and prognosis in pulmonary hypertension patients hospitalized for right heart failureLisa M Mielniczuk
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada
Congest Heart Fail 18:151-7. 2012..89). Significant renal dysfunction is common in patients with PH and an acute decline in renal function is an important marker of in hospital death and short term mortality in right heart failure...
18F-FDG PET imaging of myocardial viability in an experienced center with access to 18F-FDG and integration with clinical management teams: the Ottawa-FIVE substudy of the PARR 2 trialArun Abraham
National Cardiac PET Centre and Division of Cardiology, Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
J Nucl Med 51:567-74. 2010..The substudy of PARR 2 that we call Ottawa-FIVE, described here, was a post hoc analysis to determine the benefit of PET in a center with experience, ready access to (18)F-FDG, and integration with clinical teams...
Acute and chronic effects of continuous positive airway pressure therapy on left ventricular systolic and diastolic function in patients with obstructive sleep apnea and congestive heart failureChris B Johnson
Department of Medicine, University of Ottawa, Ottawa, Canada
Can J Cardiol 24:697-704. 2008..Obstructive sleep apnea (OSA) may contribute to the pathogenesis of congestive heart failure (CHF). Nocturnal continuous positive airway pressure (CPAP) therapy can alleviate OSA and may have a role in the treatment of CHF patients...
Prolonged basiliximab use as an alternative to calcineurin inhibition to allow renal recovery late after heart transplantationAnjali Anselm
University of Ottawa Heart Institute, Ottawa, Ontario, Canada
J Heart Lung Transplant 27:1043-5. 2008..There are no clear guidelines for the management of ARF after heart transplantation. Different strategies include delaying initiation of CNI therapy post transplant, and the use of anti-CD25 monoclonal antibodies...
Does FDG PET-assisted management of patients with left ventricular dysfunction improve quality of life? A substudy of the PARR-2 trialTushar Shukla
Molecular Function and Imaging Program, The National Cardiac PET Centre, Division of Cardiology, University of Ottawa Heart Institute and the University of Ottawa, Ottawa, Ontario, Canada
Can J Cardiol 28:54-61. 2012..Patients with left ventricular dysfunction whose management is directed by F-18-fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging may have a quality of life (QOL) benefit over standard care...
Diagnosis of graft coronary artery diseaseMalek Kass
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Curr Opin Cardiol 22:139-45. 2007..It is also not universally available. Exercise nuclear imaging is specific and can be used as a confirmatory test in patients with positive dobutamine echocardiograms...
Usefulness of beta-blocker therapy and outcomes in patients with pulmonary arterial hypertensionPetsy Pui Sze So
University of Ottawa Heart Institute, Ontario, Canada
Am J Cardiol 109:1504-9. 2012..Further randomized data are needed to evaluate the potential benefits and risks of β-blocker use in patients with PAH...
Cyclosporine reduction in the presence of everolimus: 3-month data from a Canadian pilot study of maintenance cardiac allograft recipientsHeather Ross
Department of Cardiology, Toronto General Hospital, Toronto, Ontario, Canada
J Heart Lung Transplant 27:197-202. 2008..Data are lacking regarding everolimus with reduced-dose CsA in maintenance cardiac transplant patients...
Imaging the failing right ventriclePeter R Mitoff
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Curr Opin Cardiol 27:148-53. 2012....
The 2011 Canadian Cardiovascular Society heart failure management guidelines update: focus on sleep apnea, renal dysfunction, mechanical circulatory support, and palliative careRobert S McKelvie
Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada
Can J Cardiol 27:319-38. 2011..Furthermore, patients awaiting heart transplantation who deteriorate or are otherwise not likely to survive until a donor organ is found should be referred for MCS...
Effects of ACE inhibitors on cardiac angiotensin II and aldosterone in humans: "Relevance of lipophilicity and affinity for ACE"Marcel Ruzicka
University of Ottawa Heart Institute, Ontario, Canada
Am J Hypertens 23:1179-82. 2010....
The effects of continuous positive airway pressure on myocardial energetics in patients with heart failure and obstructive sleep apneaKeiichiro Yoshinaga
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada
J Am Coll Cardiol 49:450-8. 2007..We sought to examine the short-term and longer term (6-week) effects of continuous positive airway pressure (CPAP) on myocardial energetics...
Cardiorenal syndrome and heart failureJason Reinglas
University of Ottawa Heart Institute, Ontario, Canada
Curr Opin Cardiol 25:141-7. 2010..The purpose of this review is to discuss the current definitions and mechanisms involved in this pathophysiological relationship, as well as the potential management and treatment options available for these patients...
Ultrafiltration in the management of acute decompensated heart failureLisa M Mielniczuk
University of Ottawa Heart Institute, Ontario, Canada
Curr Opin Cardiol 25:155-60. 2010..One alternative to standard therapy is mechanical fluid removal with ultrafiltration, this review will highlight the current evidence and efficacy regarding ultrafiltration use in acute heart failure...
An unusual case of hypertensive diastolic heart failure with bilateral subclavian artery stenosisBijan Jahangiri
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario
Can J Cardiol 25:111-2. 2009..A case of an apparently hypotensive patient with frequent emergency room visits for symptoms of heart failure exacerbation is presented...
Cellular transplantation: future therapeutic optionsRebecca Allan
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Curr Opin Cardiol 22:104-10. 2007..Cellular transplantation has been proposed as an alternative solution; however, clinical trials at present are small and show variable results. The mechanisms behind stem cell therapy have not yet been elucidated...
New therapies in acute decompensated heart failureNadine Gauthier
University of Ottawa Heart Institute, Division of Cardiology, Ottawa, Ontario, Canada
Curr Opin Cardiol 23:134-40. 2008..We will review the current recommendations and most recent advancement in the pharmacological treatment of acute decompensated heart failure while providing a systematic approach to the management of this prevalent condition...
Use of calcium channel blockers and angiotensin-converting enzyme inhibitors after cardiac transplantationMarie Antoinette Rockx
The University of Western Ontario, London, Ontario, Canada
Curr Opin Cardiol 22:128-32. 2007..This article reviews current data on clinical use of angiotensin-converting enzyme inhibitors and calcium channel blockers in patients who have had heart transplants...
Cardiac transplantation in HIV-positive patients: are we there yet?Bijan Jahangiri
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
J Heart Lung Transplant 26:103-7. 2007....
Prevalence and clinical implications of anemia in congestive heart failure patients followed at a specialized heart function clinicWael Elabbassi
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada K1Y 4W7
Congest Heart Fail 12:258-64. 2006..The authors conclude that anemia has strong impacts on functional class and other clinical outcomes in patients with heart failure...
Sleep apnea in chronic heart failureAnjali H Anselm
University of Ottawa Heart Institute, Division of Cardiology, Ottawa, Ontario, Canada
Curr Opin Cardiol 23:121-6. 2008..We discuss how sleep apnea may contribute to the propagation of heart failure, and how understanding its effects and reversing these effects might benefit heart failure patients...
Cardiac allograft vasculopathy: pathology, prevention and treatmentMalek Kass
University of Ottawa Heart Institute, Division of Cardiology, Ottawa, Ontario, Canada
Curr Opin Cardiol 21:132-7. 2006..SUMMARY: This review will look at the pathophysiology of graft coronary artery disease, current diagnostic and therapeutic choices, as well as existing and future directions...
Atrial natriuretic peptides in heart failure: pathophysiological significance, diagnostic and prognostic valueNina Ghosh
Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada
Can J Physiol Pharmacol 89:587-91. 2011..Furthermore, its measurement may provide incremental diagnostic value when BNP levels fall into "grey zone" levels and may be a more potent prognostic marker of mortality...
Tricuspid valve chordal tissue in endomyocardial biopsy specimens of patients with significant tricuspid regurgitationLisa Mielniczuk
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
J Heart Lung Transplant 24:1586-90. 2005..This study provides histologic evidence that chordal tissue damage can occur after cardiac biopsy, resulting in significant TVR; however, it is clinically well tolerated by affected patients...
