Brian D Gulbransen

Summary

Affiliation: University of Calgary
Country: Canada

Publications

  1. pmc Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis
    Brian D Gulbransen
    Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
    Nat Med 18:600-4. 2012
  2. pmc Nasal solitary chemoreceptor cell responses to bitter and trigeminal stimulants in vitro
    Brian D Gulbransen
    Rocky Mountain Taste and Smell Center, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Neurophysiol 99:2929-37. 2008
  3. doi Purinergic neuron-to-glia signaling in the enteric nervous system
    Brian D Gulbransen
    Hotchkiss Brain Institute, Department of Physiology and Biophysics, University of Calgary, Calgary, Alberta, Canada
    Gastroenterology 136:1349-58. 2009
  4. doi Enteric glia are targets of the sympathetic innervation of the myenteric plexus in the guinea pig distal colon
    Brian D Gulbransen
    Hotchkiss Brain Institute, Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta T2N 4N1, Canada
    J Neurosci 30:6801-9. 2010
  5. pmc Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals
    Marco Tizzano
    Rocky Mountain Taste and Smell Center, Department of Cell and Developmental Biology, University of Colorado Denver, Aurora, CO 80045, USA
    Proc Natl Acad Sci U S A 107:3210-5. 2010
  6. doi Novel functional roles for enteric glia in the gastrointestinal tract
    Brian D Gulbransen
    Hotchkiss Brain Institute, University of Calgary, 3330 Hospital Drive North West Calgary, AB T2N 4N1, Canada
    Nat Rev Gastroenterol Hepatol 9:625-32. 2012
  7. doi Interferon-gamma signals via an ERK1/2-ARF6 pathway to promote bacterial internalization by gut epithelia
    David Smyth
    Gastrointestinal Research Group, Department of Physiology and Pharmacology, The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Calgary, Alberta, Canada
    Cell Microbiol 14:1257-70. 2012
  8. pmc Solitary chemoreceptor cell proliferation in adult nasal epithelium
    Brian D Gulbransen
    Department of Cellular and Developmental Biology, Rocky Mountain Taste and Smell Center, Neuroscience Program, University of Colorado at Denver Health Sciences Center, Mail Stop 8108, P O Box 6511, Aurora, CO 80045, USA
    J Neurocytol 34:117-22. 2005

Detail Information

Publications8

  1. pmc Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis
    Brian D Gulbransen
    Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
    Nat Med 18:600-4. 2012
    ..Targeting Panx1 represents a new neuroprotective strategy to ameliorate the progression of IBD-associated dysmotility...
  2. pmc Nasal solitary chemoreceptor cell responses to bitter and trigeminal stimulants in vitro
    Brian D Gulbransen
    Rocky Mountain Taste and Smell Center, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Neurophysiol 99:2929-37. 2008
    ..Our results demonstrate that TRPM5- and gustducin-expressing nasal SCCs respond to the T2R agonist denatonium via a PLC-coupled transduction cascade typical of T2Rs in the taste system...
  3. doi Purinergic neuron-to-glia signaling in the enteric nervous system
    Brian D Gulbransen
    Hotchkiss Brain Institute, Department of Physiology and Biophysics, University of Calgary, Calgary, Alberta, Canada
    Gastroenterology 136:1349-58. 2009
    ..We investigated whether enteric glia are activated by ATP released from enteric neurons...
  4. doi Enteric glia are targets of the sympathetic innervation of the myenteric plexus in the guinea pig distal colon
    Brian D Gulbransen
    Hotchkiss Brain Institute, Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta T2N 4N1, Canada
    J Neurosci 30:6801-9. 2010
    ..Therefore, enteric glia discern activity in adjacent synaptic pathways and selectively respond to sympathetic activation...
  5. pmc Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals
    Marco Tizzano
    Rocky Mountain Taste and Smell Center, Department of Cell and Developmental Biology, University of Colorado Denver, Aurora, CO 80045, USA
    Proc Natl Acad Sci U S A 107:3210-5. 2010
    ....
  6. doi Novel functional roles for enteric glia in the gastrointestinal tract
    Brian D Gulbransen
    Hotchkiss Brain Institute, University of Calgary, 3330 Hospital Drive North West Calgary, AB T2N 4N1, Canada
    Nat Rev Gastroenterol Hepatol 9:625-32. 2012
    ..In this Review, we discuss the current body of evidence supporting functional roles of enteric glia and identify key gaps in our understanding of the physiology of these unique cells...
  7. doi Interferon-gamma signals via an ERK1/2-ARF6 pathway to promote bacterial internalization by gut epithelia
    David Smyth
    Gastrointestinal Research Group, Department of Physiology and Pharmacology, The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Calgary, Alberta, Canada
    Cell Microbiol 14:1257-70. 2012
    ..Thus, increased transcellular passage may be a major component of IFNγ-induced increases in epithelial permeability, and ERK1/2 and ARF6 are presented as important molecules in IFNγ-evoked transcytosis of bacteria across gut epithelia...
  8. pmc Solitary chemoreceptor cell proliferation in adult nasal epithelium
    Brian D Gulbransen
    Department of Cellular and Developmental Biology, Rocky Mountain Taste and Smell Center, Neuroscience Program, University of Colorado at Denver Health Sciences Center, Mail Stop 8108, P O Box 6511, Aurora, CO 80045, USA
    J Neurocytol 34:117-22. 2005
    ..No BrdU labeled cells were detected after 24 days suggesting relatively rapid replacement of the SCCs...