Research Topics
Species | Karen Ann GordonSummaryAffiliation: University of Toronto Country: Canada Publications
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Publications
Bilateral input protects the cortex from unilaterally-driven reorganization in children who are deafKaren A Gordon
CCC A, Reg CASLPO Director, Archie s Cochlear Implant Laboratory The Hospital for Sick Children Room 6D08, 555 University Avenue, Toronto, Ontario, Canada, M5G 1X8
Brain 136:1609-25. 2013..These results indicate for the first time that there is a sensitive period for bilateral auditory input in human development with implications for functional hearing...- From nucleus 24 to 513: changing cochlear implant design affects auditory response thresholdsKaren A Gordon
Archie s Cochlear Implant Laboratory, The Hospital for Sick Children, Toronto, Ontario, Canada
Otol Neurotol 34:436-42. 2013..We asked how thresholds of auditory activity evoked by a recent research cochlear implant, the Nucleus 513, compared with those evoked by previous generations of devices from the same manufacturer... - Toward a method for programming balanced bilateral cochlear implant stimulation levels in childrenKaren Ann Gordon
The Hospital for Sick Children, Toronto, Ontario, Canada
Cochlear Implants Int 13:220-7. 2012..We hypothesized that differences in stimulation levels between two CI: (1) will be observed both in behavioral and objective measures, and (2) can help to provide bilateral stimulation levels that are perceived as balanced... - Binaural interactions develop in the auditory brainstem of children who are deaf: effects of place and level of bilateral electrical stimulationKaren A Gordon
Archie s Cochlear Implant Laboratory, Hospital for Sick Children, Toronto, Ontario, Canada
J Neurosci 32:4212-23. 2012..In summary, bilateral CI stimulation is processed by the developing human auditory brainstem leading to perceptual changes in sound location and potentially improving hearing for children who are deaf... 
Binaural processing in children using bilateral cochlear implantsKaren A Gordon
The Hospital for Sick Children, Toronto, Ontario, Canada
Neuroreport 18:613-7. 2007....- Auditory brainstem activity and development evoked by apical versus basal cochlear implant electrode stimulation in childrenK A Gordon
Cochlear Implant Laboratory, The Hospital for Sick Children, and Department of Otolaryngology Head and Neck Surgery, University of Toronto, Ontario, Canada
Clin Neurophysiol 118:1671-84. 2007..We hypothesized that, in children with early onset deafness, auditory development evoked by basal electrode stimulation would differ from that evoked more apically... - Auditory development in the absence of hearing in infancyKaren Ann Gordon
Archie s Cochlear Implant Laboratory, The Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada
Neuroreport 21:163-7. 2010..Thus, activity-independent changes occurring in infancy are concentrated in the caudal auditory brainstem and likely involve the auditory nerve. Changes requiring input are most prevalent in rostral brainstem... - Effects of cochlear implant use on the electrically evoked middle latency response in childrenKaren A Gordon
Department of Otolaryngology, The Hospital for Sick Children, University of Toronto, Toronto, Ont, Canada M5G 1X8
Hear Res 204:78-89. 2005..Results suggest that the pattern of electrically evoked activity and development in the auditory thalamocortical pathways will be dependent upon the duration of auditory deprivation occurring in early childhood... - Abnormal timing delays in auditory brainstem responses evoked by bilateral cochlear implant use in childrenKaren A Gordon
Cochlear Implant Laboratory, The Hospital for Sick Children and the University of Toronto, Toronto, Ontario, Canada
Otol Neurotol 29:193-8. 2008..A period of unilateral implant use before bilateral implantation affects timing of brainstem processes measured by the electrically evoked auditory brainstem response (EABR)... - Characterizing responses from auditory cortex in young people with several years of cochlear implant experienceK A Gordon
The Cochlear Implant Program, The Cochlear Implant Laboratory, Room 6D08, The Hospital for Sick Children, 555 University Avenue, Toronto, Ont, Canada M5G 1X8
Clin Neurophysiol 119:2347-62. 2008..To determine if cortical responses evoked by a cochlear implant in children who are deaf differ from normal and to characterize these differences in children who achieve good versus fair speech perception outcomes post-implantation... - Cortical function in children receiving bilateral cochlear implants simultaneously or after a period of interimplant delayKaren A Gordon
Archie s Cochlear Implant Laboratory, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Otol Neurotol 31:1293-9. 2010..Children using bilateral cochlear implants (CIs) develop normal patterns of cortical activity when interimplant delays are minimized... - Use it or lose it? Lessons learned from the developing brains of children who are deaf and use cochlear implants to hearK A Gordon
Archie s Cochlear Implant Laboratory, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
Brain Topogr 24:204-19. 2011..Doing so has facilitated auditory development in the thalamo-cortex and allowed children who are deaf to perceive and use spoken language... - Benefits of short interimplant delays in children receiving bilateral cochlear implantsKaren A Gordon
Department of Otolaryngology Head and Neck Surgery, University of Toronto, The Hospital for Sick Children, Ontario, Canada
Otol Neurotol 30:319-31. 2009..To examine speech perception skills in quiet and noise in children using bilateral cochlear implants and to assess the influence of duration of bilateral deafness and interimplant delay... - Activity-dependent developmental plasticity of the auditory brain stem in children who use cochlear implantsKaren A Gordon
Cochlear Implant Laboratory, Department of Otolaryngology, The Hospital for Sick Children, University of Toronto, Ontario, Canada, M5G 1X8
Ear Hear 24:485-500. 2003..Specifically, is there an age of implantation after which there are no longer developmental changes in auditory brain stem activity as revealed by electrically evoked potentials?.. - Programming cochlear implant stimulation levels in infants and children with a combination of objective measuresKaren Gordon
Department of Otolaryngology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Int J Audiol 43:S28-32. 2004..Maximum levels, based on ESR thresholds measured in the OR, can be globally adjusted to maintain comfortable stimulation levels... - Multiple effects of childhood deafness on cortical activity in children receiving bilateral cochlear implants simultaneouslyK A Gordon
Archie s Cochlear Implant Laboratory, The Hospital for Sick Children, Toronto, Canada
Clin Neurophysiol 122:823-33. 2011..We therefore hypothesized that activity in the auditory cortex would be highly variable in children who are deaf... - An evoked potential study of the developmental time course of the auditory nerve and brainstem in children using cochlear implantsKaren A Gordon
Cochlear Implant Program, Department of Otolaryngology, The Hospital for Sick Children, Toronto, Canada
Audiol Neurootol 11:7-23. 2006..In sum, normal-like development of the rostral auditory brainstem is promoted by cochlear implant use in children of a wide range of ages... - What is the optimal timing for bilateral cochlear implantation in children?K A Gordon
Archie s Cochlear Implant Laboratory, The Hospital for Sick Children, Toronto, ON, Canada
Cochlear Implants Int 12:S8-14. 2011..In sum, there may be multiple sensitive periods in the developing auditory system, which must be considered when determining the optimal timing for bilateral cochlear implantation... - Atypical cortical responses underlie poor speech perception in children using cochlear implantsKaren A Gordon
Cochlear Implant Laboratory, The Hospital for Sick Children, Toronto, Ontario, Canada
Neuroreport 16:2041-5. 2005..05) than their peers with expected waveforms. Results suggest a persistent immaturity and/or abnormal organization in the auditory cortex in some children... - Lateralization of interimplant timing and level differences in children who use bilateral cochlear implantsClaire A M Salloum
Institute of Medical Science, University of Toronto, Canada
Ear Hear 31:441-56. 2010..Our working hypothesis was that children using bilateral CIs are able to perceive changes in ITDs and ILDs similar to their normal-hearing (NH) peers... - Neural response telemetry in 12- to 24-month-old childrenKaren A Gordon
Cochlear Implant Program, Department of Otolaryngology, The Hospital for Sick Children and the University of Toronto, Canada
Ann Otol Rhinol Laryngol Suppl 189:42-8. 2002..A correction factor applied to EAP thresholds provided useful predictions of T levels. The EAPs can be used to ensure that even very young children receive auditory stimulation with their cochlear implants upon device activation... - Speech perception outcome in multiply disabled children following cochlear implantation: investigating a predictive scoreKeith Trimble
Department of Otolaryngology Head and Neck Surgery, The Hospital for Sick Children, 555 University Avenue, Toronto, M5G 1X8, Canada
J Am Acad Audiol 19:602-11; quiz 651. 2008.... - Vestibular end-organ and balance deficits after meningitis and cochlear implantation in children correlate poorly with functional outcomeSharon L Cushing
Department of Otolaryngology Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Otol Neurotol 30:488-95. 2009..Assess vestibular and balance function in meningitis-induced profound sensorineural hearing loss (SNHL)... - Facial nerve electromyography: a useful tool in detecting nonauditory side effects of cochlear implantationSharon L Cushing
Cochlear Implant Program, Department of Otolaryngology, The Hospital for Sick Children and the University of Toronto, Toronto, Ontario
J Otolaryngol Head Neck Surg 38:157-65. 2009..For children with facial nerve stimulation, the long-term implications implant use are unclear... - Beamformer suppression of cochlear implant artifacts in an electroencephalography datasetDaniel D E Wong
Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON M5S3G9, Canada
IEEE Trans Biomed Eng 56:2851-7. 2009..The effectiveness of the method is then demonstrated using simulated data and electroencephalography data from a CI user... - Chorda tympani nerve function in children: relationship to otitis media and body mass indexRaewyn M Seaberg
Department of Otolaryngology Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Int J Pediatr Otorhinolaryngol 74:1393-6. 2010..We sought to test this directly by measuring chorda tympani nerve function in children with and without a previous history of acute otitis media and to determine the relationship to body mass index... - Bilateral cochlear implantation in children with anomalous cochleovestibular anatomyNeil K Chadha
Department of Otolaryngology, The Hospital for Sick Children, Toronto, ON, Canada
Arch Otolaryngol Head Neck Surg 135:903-9. 2009..To outline clinical experience with bilateral cochlear implantation in children with cochleovestibular anomalies... - Incidence and characteristics of facial nerve stimulation in children with cochlear implantsSharon L Cushing
Cochlear Implant Program, Department of Otolaryngology, The Hospital for Sick Children and the University of Toronto, Toronto, Canada
Laryngoscope 116:1787-91. 2006..Part A consisted of a prospective study of a randomized sample of 44 pediatric implant users. Part B consisted of a retrospective analysis of 121 children with previously recorded electrically evoked auditory brainstem responses (EABR)... - Tinnitus is prevalent in children with cochlear implantsNeil K Chadha
Department of Otolaryngology, The Hospital for Sick Children, Toronto, Ontario, Canada
Int J Pediatr Otorhinolaryngol 73:671-5. 2009..To explore the prevalence and the perceived impact of tinnitus in children using cochlear implants... - Temporal bone findings on computed tomography imaging in branchio-oto-renal syndromeEvan J Propst
Department of Otolaryngology, The Hospital for Sick Children, Toronto, Ontario, Canada
Laryngoscope 115:1855-62. 2005..We ask if it is possible for the untrained observer to use a battery of CT observations as a tool in the overall evaluation of the BOR phenotype... - Auditory responses in cochlear implant users with and without GJB2 deafnessEvan Jon Propst
Department of Otolaryngology Head and Neck Surgery and the Molecular Genetics Laboratory, The Hospital for Sick Children, Toronto, Ontario, Canada
Laryngoscope 116:317-27. 2006..We assessed this by measuring patterns of neural activity and hearing from apical versus basal cochlear implant electrode regions... - Temporal bone imaging in GJB2 deafnessEvan J Propst
Cochlear Implant Program, Department of Otolaryngology Head and Neck Surgery, Molecular Genetics Laboratory, The Hospital for Sick Children, Toronto, Canada
Laryngoscope 116:2178-86. 2006..To describe temporal bone findings on computed tomography (CT) imaging in GJB2-related hearing loss (HL). We asked whether evaluation of the temporal bone is required in individuals with biallelic GJB2 mutations... - Toward a battery of behavioral and objective measures to achieve optimal cochlear implant stimulation levels in childrenKaren A Gordon
Cochlear Implant Program, Department of Otolaryngology, The Hospital for Sick Children and the University of Toronto, Room 6D08, Toronto, ON, Canada M5G 1X8
Ear Hear 25:447-63. 2004..the first year of implant use? 3) Do ECAP, EABR, and ESR thresholds or behavioral measures change over time? 4) What is the relation between ECAP, EABR, and ESR thresholds and behavioral measures of threshold and comfortably loud levels?.. - Bilateral cochlear implants should be the standard for children with bilateral sensorineural deafnessBlake C Papsin
Department of Otolaryngology, Faculty of Medicine, University of Toronto, Canada
Curr Opin Otolaryngol Head Neck Surg 16:69-74. 2008..Arguments against implantation, which prevailed for many years, are countered by some of the findings reported over the past 1-2 years... - A test of static and dynamic balance function in children with cochlear implants: the vestibular olympicsSharon L Cushing
Department of Otolaryngology Head and Neck Surgery, University of Toronto, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada
Arch Otolaryngol Head Neck Surg 134:34-8. 2008..To determine the incidence of static and dynamic balance dysfunction in a group of children with profound sensorineural hearing loss receiving a cochlear implant and to assess the impact of cochlear implant activation on equilibrium... - Effects of stimulus manipulation on electrophysiological responses in pediatric cochlear implant users. Part I: duration effectsTaryn Davids
Hospital for Sick Children Department of Otolaryngology Head and Neck Surgery, 6th Floor, Elm Wing, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8
Hear Res 244:7-14. 2008.... - Effects of stimulus manipulation on electrophysiological responses of pediatric cochlear implant users. Part II: rate effectsTaryn Davids
Department of Otolaryngology, Head and Neck Surgery, 6th Floor, Elm Wing, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8
Hear Res 244:15-24. 2008.... - Evidence of vestibular and balance dysfunction in children with profound sensorineural hearing loss using cochlear implantsSharon L Cushing
Department of Otolaryngology Head and Neck Surgery, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada
Laryngoscope 118:1814-23. 2008..This hypothesis was studied in 40 children with severe to profound SNHL and unilateral cochlear implants... - Recognition of affective speech prosody and facial affect in deaf children with unilateral right cochlear implantsTalar M Hopyan-Misakyan
Department of Psychology, Neurosciences and Mental Health Program, Hospital for Sick Children, Toronto, Canada
Child Neuropsychol 15:136-46. 2009..It is not known whether childhood CI users can identify emotion in speech and faces, so we investigated speech prosody and facial affect in children who had been deaf from infancy and experienced CI users... - Ethnicity and mutations in GJB2 (connexin 26) and GJB6 (connexin 30) in a multi-cultural Canadian paediatric Cochlear Implant ProgramEvan Jon Propst
Cochlear Implant Program, Department of Otolaryngology, The Hospital for Sick Children, Toronto, Ont, Canada M5G 1X8
Int J Pediatr Otorhinolaryngol 70:435-44. 2006..To determine the relationship between ethnicity and mutations in the GJB2 and GJB6 genes in multi-cultural patients enrolled in a Canadian paediatric Cochlear Implant Program... - Dose-dependent suppression of the electrically elicited stapedius reflex by general anesthetics in children undergoing cochlear implant surgeryMark W Crawford
Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Anesth Analg 108:1480-7. 2009..In this study, we evaluated the dose-related effects of sevoflurane, desflurane, isoflurane, and propofol on the intraoperative ESRT and ECAP... - Auditory brain stem and midbrain development after cochlear implantation in childrenKaren A Gordon
Department of Otolaryngology, The Hospital for Sick Children, Toronto, ON, Canada
Ann Otol Rhinol Laryngol Suppl 189:32-7. 2002..The decreasing latencies likely reflect decreased neural conduction times at this level, in part because of increased synaptic efficacy... - Is there a critical period for cochlear implantation in congenitally deaf children? Analyses of hearing and speech perception performance after implantationRobert V Harrison
Auditory Science Laboratory, Department of Otolaryngology, Division of Brain and Behaviour, The Hospital for Sick Children, Toronto M5G 1X8, Canada
Dev Psychobiol 46:252-61. 2005..We observed distinct age-of-implant cutoffs, and will discuss whether these really represent critical periods during development... - Soft tissue complications after small incision pediatric cochlear implantationTaryn Davids
Cochlear Implant Lab, Department of Otolaryngology, Hospital for Sick Children, Toronto, Ontario, Canada
Laryngoscope 119:980-3. 2009..To report and analyze the soft tissue complications of 462 consecutive cochlear implants using a minimal access approach at a single institution... - Effect of increasing duration of stimulation on the electrically evoked auditory brainstem and middle latency responses in pediatric cochlear implant usersTaryn Davids
Division of Otolaryngology Head and Neck Surgery, University of Toronto, Toronto, Ontario
J Otolaryngol Head Neck Surg 37:559-64. 2008..We asked if auditory brainstem and middle latency responses can be reliably measured using electrical pulse trains of increasing duration... - Cochlear implants for children with severe-to-profound hearing lossBlake C Papsin
Department of Otolaryngology, Hospital for Sick Children, Toronto, Canada
N Engl J Med 357:2380-7. 2007 - Bilateral simultaneous cochlear implantation in children: our first 50 casesJames D Ramsden
Department of Otolaryngology, Hospital for Sick Children, Toronto, Canada
Laryngoscope 119:2444-8. 2009..To assess the safety and surgical technique of bilateral simultaneous cochlear implantation in children... - Bone-anchored hearing aids in infants and children younger than 5 yearsTaryn Davids
Department of Otolaryngology and Otolaryngology Head and Neck Surgery, The Hospital for Sick Children, Toronto, Ontario, USA
Arch Otolaryngol Head Neck Surg 133:51-5. 2007....