Brien M, Duval C, Palacios J, Boufaied I, Hudon Thibeault A, Nadeau Vallée M, et al. Uric Acid Crystals Induce Placental Inflammation and Alter Trophoblast Function via an IL-1-Dependent Pathway: Implications for Fetal Growth Restriction. J Immunol. 2017;198:443-451 pubmed
..Furthermore, our study describes a novel in vivo animal model of noninfectious inflammation during pregnancy, which is triggered by MSU crystals and leads to reduced fetal growth. ..