Research Topics
| J S GillSummaryAffiliation: University of British Columbia Country: Canada Publications
Research Grants
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Detail Information
Publications
Preemptive kidney transplantation: the advantage and the advantagedBertram L Kasiske
The United States Renal Data System Coordinating Center, Minneapolis, Minnesota 55414, USA
J Am Soc Nephrol 13:1358-64. 2002..Alterations in the payment system, emphasis on early referral, and changes in cadaver kidney allocation could increase the number of patients who benefit from preemptive transplantation...
Screening for de novo anti-human leukocyte antigen antibodies in nonsensitized kidney transplant recipients does not predict acute rejectionJohn S Gill
Division of Nephrology, St Paul s Hospital, University of British Columbia, Vancouver, BC, Canada
Transplantation 89:178-84. 2010....
Design and implementation of the Canadian Kidney Disease Cohort Study (CKDCS): A prospective observational study of incident hemodialysis patientsAminu K Bello
Department of Medicine, University of Alberta, Edmonton, Canada
BMC Nephrol 12:10. 2011..This study focuses on delineating potentially reversible determinants of adverse outcomes that occur in patients receiving dialysis for end-stage renal disease (ESRD)...- Trace elements in hemodialysis patients: a systematic review and meta-analysisMarcello Tonelli
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
BMC Med 7:25. 2009..We conducted a systematic review to summarize existing literature on trace element status in hemodialysis patients... - Cardiovascular events and investigation in patients who are awaiting cadaveric kidney transplantationJohn S Gill
Division of Nephrology, University of British Columbia, St Paul s Hospital, Providence 6a, 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6
J Am Soc Nephrol 16:808-16. 2005..Initial cardiac investigations have limited value in guiding the timing of patient reevaluation after wait-listing. Periodic surveillance cardiac investigation after wait-listing may be unnecessary and requires further study... - The older living kidney donor: Part of the solution to the organ shortageJohn S Gill
Department of Nephrology, St Paul s Hospital, University of British Columbia, Vancouver, British Columbia, Canada
Transplantation 82:1662-6. 2006..Strategies to increase kidney transplantation are urgently needed... - Potential advantages and limitations of applying the chronic kidney disease classification to kidney transplant recipientsJ S Gill
Division of Nephrology, University of British Columbia, St Paul s Hospital, Vancouver, British Columbia, Canada
Am J Transplant 6:2821-6. 2006..The CKD classification thus represents an exciting potential strategy to improve clinical outcomes that should be adopted, further studied and modified to incorporate considerations unique to KTRs... - The impact of waiting time and comorbid conditions on the survival benefit of kidney transplantationJohn S Gill
Division of Nephrology, Department of Medicine, University of British Columbia, Vancouver, Canada
Kidney Int 68:2345-51. 2005..Longer waiting times may limit the survival benefit of kidney transplantation in older patients or those with a high burden of comorbid disease... - Access to kidney transplantation: the limitations of our current understandingJohn S Gill
Division of Nephrology, St Paul s Hospital, University of British Columbia, Vancouver, British Columbia Canada
J Nephrol 20:501-6. 2007..The information provided will aid the reader to critically assess issues related to patient access to KTX... - Cardiovascular disease in transplant recipients: current and future treatment strategiesJohn S Gill
Division of Nephrology, University of British Columbia, St Paul s Hospital, Providence Building, Ward 6a, 1081 Burrard Street, Vancouver, BC, Canada, V6Z 1Y6
Clin J Am Soc Nephrol 3:S29-37. 2008.... - Why do preemptive kidney transplant recipients have an allograft survival advantage?John S Gill
Division of Nephrology, St Paul s Hospital Vancouver, BC, Canada
Transplantation 78:873-9. 2004.... - Deceased organ donation in Canada: an opportunity to heal a fractured systemJ S Gill
Division of Nephrology, University of British Columbia, St Paul s Hospital, Vancouver, BC, Canada
Am J Transplant 8:1580-7. 2008.... - Managing patients with a failed kidney transplant: how can we do better?John S Gill
St Paul s Hospital, Providence Building Ward, Burrard St, Vancouver, British Columbia, Canada
Curr Opin Nephrol Hypertens 20:616-21. 2011.... - The pregnancy rate and live birth rate in kidney transplant recipientsJ S Gill
Department of Medicine, University of British Columbia, Vancouver, Canada
Am J Transplant 9:1541-9. 2009..The live birth rate was substantially lower than reported in voluntary registries of transplant recipients, and the proportion of pregnancies resulting in unexpected fetal loss increased over time... - The importance of transitions between dialysis and transplantation in the care of end-stage renal disease patientsJ S Gill
Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada
Kidney Int 71:442-7. 2007.... - Access to kidney transplantation among patients insured by the United States Department of Veterans AffairsJohn S Gill
Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada
J Am Soc Nephrol 18:2592-9. 2007..We conclude that VA-insured patients are less likely to receive transplants than privately insured patients, and that further studies are needed to identify the reasons for this disparity... - The effect of maintenance immunosuppression medication on the change in kidney allograft functionJohn S Gill
Division of Nephrology, St Paul s Hospital, Vancouver, British Columbia, Canada
Kidney Int 65:692-9. 2004..In this study we determined the effect of maintenance immunosuppression medications on the rate of kidney allograft function loss defined by the annualized change in glomerular filtration rate (GFR)... - Patient and allograft survival of Indo Asian and East Asian dialysis patients treated in CanadaM Tonelli
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Kidney Int 72:499-504. 2007..These findings warrant further study, especially given the good graft outcomes in these individuals... - Mortality of Canadians treated by peritoneal dialysis in remote locationsM Tonelli
Division of Nephrology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Kidney Int 72:1023-8. 2007..Further study into the quality of care delivered to remote-dwelling patients on peritoneal dialysis is needed... - Nephrectomy after transplant failure: current practice and outcomesO Johnston
Division of Nephrology, University of British Columbia, St Paul s Hospital, Vancouver, B C, Canada
Am J Transplant 7:1961-7. 2007..The role of nephrectomy in the management of dialysis treated transplant failure patients, and the implications of nephrectomy for repeat transplantation should be further studied in prospective studies... - Association between residence location and likelihood of kidney transplantation in Aboriginal patients treated with dialysis in CanadaM Tonelli
Division of Nephrology, Department of Medicine, University of Alberta, Edmonton, Alberta, and Division of Nephrology, St Paul s Hospital, Vancouver, British Columbia, Canada
Kidney Int 70:924-30. 2006..In conclusion, remote location of residence does not explain the lower rate of kidney transplantation among Aboriginal people treated for ESRD in Canada... - Recipient outcomes for expanded criteria living kidney donors: the disconnect between current evidence and practiceY Iordanous
Division of Nephrology, University of Western Ontario, London, Ontario, Canada
Am J Transplant 9:1558-73. 2009..This disconnect between donor selection and a lack of knowledge of recipient outcomes should give transplant decision-makers pause and sets an agenda for future research... - The impact of pancreas transplantation on kidney allograft survivalS Browne
Division of Nephrology, University of British Columbia, Vancouver, Canada
Am J Transplant 11:1951-8. 2011..We conclude that PAK is associated with improved kidney allograft survival, and pre-PAK GFR 30-39 mL/min should not preclude PAK. Expanded use of PAK is warranted... - Income of living kidney donors and the income difference between living kidney donors and their recipients in the United StatesJ S Gill
Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada Tufts New England Medical Center, Boston, MA Center for Health Evaluation and Outcomes Sciences, Vancouver, British Columbia, Canada Division of Nephrology, University of Calgary, Calgary, Alberta, Canada Department of Medicine, University of Alberta, Edmonton, Alberta, Canada Alberta Kidney Disease Network, Edmonton, Alberta, Canada
Am J Transplant 12:3111-8. 2012..We conclude that most donors and recipients have similar modest incomes, suggesting that the costs of donation are a significant burden in the majority of living donor transplants... - A matched cohort pharmacoepidemiological analysis of steroid free immunosuppression in renal transplantationKatherine A Barraclough
Division of Nephrology, Vancouver General Hospital, Diamond Health Care Centre, Vancouver BC, Canada
Transplantation 87:672-80. 2009.... - The advanced age deceased kidney donor: current outcomes and future opportunitiesY Mun Woo
Divisions of Nephrology, University of British Columbia, St. Paul's Hospital, Vancouver, British Columbia, Canada
Kidney Int 67:2407-14. 2005..Future studies to maximize initial GFR and minimize early loss of GFR in recipients of donors > or =55 years may lead to improved outcomes from deceased donors > or =55 years... - H-Y incompatibility predicts short-term outcomes for kidney transplant recipientsS Joseph Kim
Division of Nephrology, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
J Am Soc Nephrol 20:2025-33. 2009..In conclusion, compared with other recipient-donor gender combinations, female recipients of male donor kidney transplants in the United States have an increased short-term risk but not long-term risk for adverse outcomes... - Quantification of the early risk of death in elderly kidney transplant recipientsJ S Gill
Division of Nephrology, University of British Columbia, Vancouver, Canada Tufts New England Medical Center, Boston, MA Center for Health Evaluation and Outcomes Sciences, St Paul s Hospital, Vancouver, British Columbia, Canada
Am J Transplant 13:427-32. 2013..Early posttransplant mortality risk is eliminated in low- and intermediate-risk patients, and markedly reduced in high-risk patients with LD transplantation... - The long-term quality of life of living kidney donors: a multicenter cohort studyK Clemens
Division of Nephrology, University of Western Ontario, London, Ontario, Canada
Am J Transplant 11:463-9. 2011..Our findings are reassuring for the practice of living transplantation. Those who donate a kidney in centers that use routine pretransplant donor evaluation have good long-term quality of life... - Survival among nocturnal home haemodialysis patients compared to kidney transplant recipientsRobert P Pauly
Department of Medicine, University of Alberta Hospital, University of Alberta, Edmonton, AB, Canada
Nephrol Dial Transplant 24:2915-9. 2009..To date, no studies have compared survival in patients treated with NHD and kidney transplantation... - The change in allograft function among long-term kidney transplant recipientsJohn S Gill
Division of Nephrology, St. Paul's Hospital, Vancouver, British Columbia, Canada
J Am Soc Nephrol 14:1636-42. 2003..Strategies to improve long-term kidney allograft survival that increase baseline allograft function may be more effective than strategies to slow the decline in GFR... - Sirolimus is associated with new-onset diabetes in kidney transplant recipientsOlwyn Johnston
Division of Nephrology, St Paul s Hospital, University of British Columbia, 1081 Burrard Street, Vancouver, BC, Canada
J Am Soc Nephrol 19:1411-8. 2008..Given the negative impact of NOD on posttransplantation outcomes, these findings should be confirmed in prospective studies or in meta-analyses of existing trials that involved sirolimus... - Cancer mortality in kidney transplantationB A Kiberd
Department of Medicine, Dalhousie University, Halifax Nova Scotia, British Columbia, Canada
Am J Transplant 9:1868-75. 2009..These findings challenge the notion that cancer is a major cause of premature death in all kidney transplant recipients and has implications for design of cancer prevention strategies in kidney transplant recipients... - Death and renal transplantation among Aboriginal people undergoing dialysisMarcello Tonelli
Department of Medicine, Division of Nephrology, University of Alberta, Edmonton, Alta
CMAJ 171:577-82. 2004..We evaluated differences in survival and rate of renal transplantation among Aboriginal and white patients after initiation of dialysis... - Treatment of polyomavirus infection in kidney transplant recipients: a systematic reviewOlwyn Johnston
Division of Nephrology, University of British Columbia, Vancouver, BC, Canada
Transplantation 89:1057-70. 2010..However, the evidence base is poor and highlights the urgent need for adequately powered randomized trials to define the optimal treatment of this important condition... - Colon and rectal cancer after renal transplantationManstein Kan
Department of Surgery, St Paul s Hospital, University of British Columbia, C303 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
Expert Rev Anticancer Ther 8:1339-46. 2008..This article reviews the current literature evaluating CRC diagnosed in PRTPs, focusing on clinical characteristics and treatment outcomes... - Differences in use of peritoneal dialysis and survival among East Asian, Indo Asian, and white ESRD patients in CanadaBrenda R Hemmelgarn
Department of Medicine, Division of Nephrology, University of Calgary, Canada
Am J Kidney Dis 48:964-71. 2006..Racial differences in health outcomes in general are well documented; however, few studies examined the impact of East Asian and Indo Asian race on choice of dialytic modality and survival among patients with end-stage renal disease (ESRD)... - Chronic kidney disease progression in native and transplant kidneysY Mun Woo
Nephrology, University of British Columbia, St. Paul's Hospital, 1081 Burrard Street, Vancouver, B.C Canada V6Z 1Y6
Curr Opin Nephrol Hypertens 13:607-11. 2004..Prospective studies to determine the importance of nonimmune factors such as hypertension, proteinuria, dyslipidemia, diabetes, and anemia in the transplant setting are needed... - C4d deposition in acute rejection: an independent long-term prognostic factorAndrew M Herzenberg
Department of Pathology and Laboratory Medicine, St. Paul's Hospital, Vancouver, British Columbia, Canada
J Am Soc Nephrol 13:234-41. 2002..Peritubular C4d deposition is a significant predictor of graft survival rates and is independent of histologic rejection type and a variety of clinical prognostic factors... - Prevention of sepsis during the transition to dialysis may improve the survival of transplant failure patientsOlwyn Johnston
University of British Columbia, St Paul s Hospital, Vancouver, BC, Canada
J Am Soc Nephrol 18:1331-7. 2007..93; 95% CI 2.64 to 3.24; P < 0.001). Strategies to prevent sepsis during the transition from transplantation to dialysis may improve the survival of patients with allograft failure... - Residence location and likelihood of kidney transplantationMarcello Tonelli
Division of Nephrology and Transplant Immunology, Department of Medicine, University of Alberta, Edmonton, Alta
CMAJ 175:478-82. 2006..Within each region we also determined whether distance from the closest transplant centre was associated with the likelihood of transplantation... - Opportunities to improve the care of patients with kidney transplant failureJohn S Gill
Division of Nephrology, New England Medical Center, Boston, Massachusetts 02111, USA
Kidney Int 61:2193-200. 2002..Exposure to immunosuppressive medications differentiates these patients from the general incident end-stage renal disease (ESRD) population... - Mortality after kidney transplant failure: the impact of non-immunologic factorsJohn S Gill
Department of Nephrology, Tufts-New England Medical Center, Boston, Massachusetts, USA
Kidney Int 62:1875-83. 2002..Prevention, early diagnosis and treatment of co-morbid conditions and the complications of chronic kidney disease may improve the survival of patients with transplant failure... - Death in the first year after kidney transplantation: implications for patients on the transplant waiting listJohn S Gill
Division of Nephrology, Tufts-New England Medical Center, Boston, MA, USA
Transplantation 75:113-7. 2003..Alternate organ allocation strategies that facilitate patient assessment close to the time of transplantation or that prioritize high-risk patients may also improve outcomes... - Chronic kidney disease and the transplant recipientJohn S Gill
Division of Nephrology, Tufts-New England Medical Center, Boston, Mass 02111, USA
Blood Purif 21:137-42. 2003.... - Use and outcomes of peritoneal dialysis among Aboriginal people in CanadaMarcello Tonelli
Division of Nephrology, University of Alberta, 7 129 Clinical Science Building 8440, 112 Street, Edmonton, Alberta T6G 2G3 Canada
J Am Soc Nephrol 16:482-8. 2005..Future studies should address barriers to the initiation and maintenance of PD in the Aboriginal population, especially those who reside in rural locations... - Outcomes of kidney transplantation from older living donors to older recipientsJagbir Gill
Division of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Am J Kidney Dis 52:541-52. 2008..As waiting times for a deceased donor kidney increase, these older candidates are disadvantaged by rapidly deteriorating health, often resulting in death or removal from the wait list before transplantation... - Impact of acute rejection and new-onset diabetes on long-term transplant graft and patient survivalEdward H Cole
Division of Nephrology and Multiorgan Transplant Programme, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada
Clin J Am Soc Nephrol 3:814-21. 2008..Development of new therapeutic strategies to improve long-term transplant outcomes requires improved understanding of the mechanisms by which these complications limit long-term transplant survival... - Outcomes of dual adult kidney transplants in the United States: an analysis of the OPTN/UNOS databaseJagbir Gill
David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
Transplantation 85:62-8. 2008..There are limited data comparing outcomes of DKT to single kidney ECD transplants, making it unclear where DKT fits in the current allocation scheme. Our purpose was to compare outcomes of DKT and ECD transplants in the United States... - Association between proximity to the attending nephrologist and mortality among patients receiving hemodialysisMarcello Tonelli
Division of Nephrology and Transplant Immunology, Department of Medicine, University of Alberta, Edmonton, Alta
CMAJ 177:1039-44. 2007..We investigated whether patients receiving hemodialysis who live farther from their attending nephrologist are more likely to die than those who live closer...
Research Grants
- Regulation of GnRH Neuronal Development by FGF SignalingJohn Gill; Fiscal Year: 2005..Critical stages of GnRH neuron development will be evaluated in mice to discern the functional contribution of FGF signaling in this important neuroendocrine system. ..