R Gandhi

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Survival and clinical function of cemented and uncemented prostheses in total knee replacement: a meta-analysis
    R Gandhi
    Toronto Western Hospital, 399 Bathurst St, East Wing 1 435, Toronto, Ontario, Canada
    J Bone Joint Surg Br 91:889-95. 2009
  2. pmc Fractures in the elderly: when is hip replacement a necessity?
    Prasad Antapur
    Toronto Western Hospital, Toronto, Ontario, Canada
    Clin Interv Aging 6:1-7. 2011
  3. pmc The role of surgeon volume on patient outcome in total knee arthroplasty: a systematic review of the literature
    Rick L Lau
    Division of Orthopaedics, Department of Surgery Kingston General Hospital, Queen s University, 76 Stuart St, Nickle 3, Rm 9 309, Kingston, ON K7L 2V7, Canada
    BMC Musculoskelet Disord 13:250. 2012
  4. pmc TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts
    Alison M Connor
    Arthritis and Immune Disorder Research Centre, University Health Network, Toronto Medical Discovery Tower, 10th Floor, Room 10 358, 101 College Street, Toronto, Ontario M5G 1L7, Canada
    Arthritis Res Ther 14:R62. 2012
  5. doi request reprint Inflammatory predictors of ongoing pain 2 years following knee replacement surgery
    Rajiv Gandhi
    Division of Orthopaedic Surgery, University Health Network, University of Toronto, Toronto ON, Canada
    Knee 20:316-8. 2013
  6. doi request reprint BMI independently predicts younger age at hip and knee replacement
    Rajiv Gandhi
    Division of Orthopaedic Surgery, University Health Network, Toronto, Ontario, Canada
    Obesity (Silver Spring) 18:2362-6. 2010
  7. ncbi request reprint Greater perceived helplessness in osteoarthritis predicts outcome of joint replacement surgery
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 36:1507-11. 2009
  8. doi request reprint Predicting the longer term outcomes of total knee arthroplasty
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto ON, Canada M5T 2S8
    Knee 17:15-8. 2010
  9. ncbi request reprint Metabolic syndrome and the incidence of symptomatic deep vein thrombosis following total knee arthroplasty
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, ON, Canada
    J Rheumatol 36:2298-301. 2009
  10. ncbi request reprint Ethnic differences in the relationship between obesity and joint pain and function in a joint arthroplasty population
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, Canada
    J Rheumatol 35:1874-7. 2008

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Survival and clinical function of cemented and uncemented prostheses in total knee replacement: a meta-analysis
    R Gandhi
    Toronto Western Hospital, 399 Bathurst St, East Wing 1 435, Toronto, Ontario, Canada
    J Bone Joint Surg Br 91:889-95. 2009
    ..005 (95% CI -0.26 to 0.26) (p = 0.972). There was improved survival of the cemented compared to uncemented implants, with no statistically significant difference in the mean Knee Society score between groups for all pooled data...
  2. pmc Fractures in the elderly: when is hip replacement a necessity?
    Prasad Antapur
    Toronto Western Hospital, Toronto, Ontario, Canada
    Clin Interv Aging 6:1-7. 2011
    ..This article reviews the current literature and indications for a primary total hip replacement in these patients...
  3. pmc The role of surgeon volume on patient outcome in total knee arthroplasty: a systematic review of the literature
    Rick L Lau
    Division of Orthopaedics, Department of Surgery Kingston General Hospital, Queen s University, 76 Stuart St, Nickle 3, Rm 9 309, Kingston, ON K7L 2V7, Canada
    BMC Musculoskelet Disord 13:250. 2012
    ....
  4. pmc TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts
    Alison M Connor
    Arthritis and Immune Disorder Research Centre, University Health Network, Toronto Medical Discovery Tower, 10th Floor, Room 10 358, 101 College Street, Toronto, Ontario M5G 1L7, Canada
    Arthritis Res Ther 14:R62. 2012
    ..We hypothesized that the activity of the protein degradation pathways would be increased in response to TNFα stimulation in RA synovial fibroblasts compared with control fibroblasts...
  5. doi request reprint Inflammatory predictors of ongoing pain 2 years following knee replacement surgery
    Rajiv Gandhi
    Division of Orthopaedic Surgery, University Health Network, University of Toronto, Toronto ON, Canada
    Knee 20:316-8. 2013
    ..The prevalence of unrelieved pain following total knee arthroplasty (TKA) is substantial...
  6. doi request reprint BMI independently predicts younger age at hip and knee replacement
    Rajiv Gandhi
    Division of Orthopaedic Surgery, University Health Network, Toronto, Ontario, Canada
    Obesity (Silver Spring) 18:2362-6. 2010
    ..05). Our study indicates that obese patients, especially those with a BMI ≥ 35 kg/m(2), presented for and underwent joint replacement surgery at a younger age as compared to nonobese patients...
  7. ncbi request reprint Greater perceived helplessness in osteoarthritis predicts outcome of joint replacement surgery
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 36:1507-11. 2009
    ....
  8. doi request reprint Predicting the longer term outcomes of total knee arthroplasty
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto ON, Canada M5T 2S8
    Knee 17:15-8. 2010
    ..05). Knowledge of these factors that predict outcomes should be used in setting appropriate patient expectations of surgery...
  9. ncbi request reprint Metabolic syndrome and the incidence of symptomatic deep vein thrombosis following total knee arthroplasty
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, ON, Canada
    J Rheumatol 36:2298-301. 2009
    ..We asked if patients with metabolic syndrome undergoing total knee replacement (TKR) have an increased risk for symptomatic deep vein thrombosis (DVT) at 3 months followup...
  10. ncbi request reprint Ethnic differences in the relationship between obesity and joint pain and function in a joint arthroplasty population
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, Canada
    J Rheumatol 35:1874-7. 2008
    ..We investigated the influence of obesity on joint pain and function in Asians as compared to Caucasians with degenerative hip and knee arthritis...
  11. pmc The relation between body mass index and waist-hip ratio in knee osteoarthritis
    Rajiv Gandhi
    the Division of Orthopaedic Surgery, University Health Network and the Department of Surgery, University of Toronto, Toronto, Ont, Canada
    Can J Surg 53:151-4. 2010
    ..Our intent was to examine the relation between waist-hip ratio (WHR) and body mass index (BMI) as a measurement of body habitus in patients with end-stage knee osteoarthritis (OA)...
  12. doi request reprint Relationship between body habitus and joint leptin levels in a knee osteoarthritis population
    Rajiv Gandhi
    Division of Orthopaedic Surgery, Toronto Western Hospital, University Health Network, 399 Bathurst Street, East Wing 1 439, Toronto, Ontario M5T 2S8, Canada
    J Orthop Res 28:329-33. 2010
    ..05). WC may be a more accurate measure of body habitus than BMI in the relationship between the metabolic effects of adipose tissue and OA...
  13. pmc Outcomes of total joint arthroplasty in academic versus community hospitals
    Rajiv Gandhi
    Division of Orthopedic Surgery, Toronto Western Hospital and University of Toronto, Toronto, Ont
    Can J Surg 52:413-6. 2009
    ..Most joint-replacement surgeries are currently performed in community hospitals. We sought to determine whether the functional outcomes of joint-replacement surgery differ between academic and community hospitals...
  14. pmc Effect of sex and living arrangement on the timing and outcome of joint replacement surgery
    Rajiv Gandhi
    Department of Surgery, University of Toronto, Toronto, Ont
    Can J Surg 53:37-41. 2010
    ..We investigated the impact living status (alone or with another person) and sex on the timing and outcomes of hip and knee replacement surgery...
  15. doi request reprint Predicting patient dissatisfaction following joint replacement surgery
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 35:2415-8. 2008
    ..The incidence of patient-reported dissatisfaction following total joint arthroplasty can be up to 30%. Our aim was to identify the preoperative patient-level predictors of patient dissatisfaction 1 year after surgery...
  16. doi request reprint Metabolic syndrome and the functional outcomes of hip and knee arthroplasty
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, Canada
    J Rheumatol 37:1917-22. 2010
    ..We investigated the influence of risk factors of metabolic syndrome (MetS) on patient function before and after hip and knee replacement surgery...
  17. doi request reprint Relationship between self-reported and performance-based tests in a hip and knee joint replacement population
    Rajiv Gandhi
    Division of Orthopaedic Surgery, University Health Network Department of Surgery, University of Toronto, Toronto, ON, Canada
    Clin Rheumatol 28:253-7. 2009
    ..004) and preoperative TUG scores (p < 0.0001). Given low-to-moderate relationship between self-reported and performance-based tools, both tests are needed to assess the true level of patient disability...
  18. pmc Comparison of published orthopaedic trauma trials following registration in Clinicaltrials.gov
    Rajiv Gandhi
    Toronto Western Hospital EW 1 439, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada
    BMC Musculoskelet Disord 12:278. 2011
    ..Our primary objective was to determine publication rates for orthopaedic trauma trials registered with ClinicalTrials.gov. We further evaluated methodological consistency between registration and publication...
  19. doi request reprint Bilateral non-union of high tibial osteotomies treated by total knee arthroplasty: a case report
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada M5T 2S8
    Knee 15:242-5. 2008
    ..At minimum 1 year follow-up, she was walking pain free with full knee range of motion. We found that primary total knee replacement (TKR) using tibial stems and without treating the tibial non-union gave satisfactory results...
  20. pmc Computer navigation in total hip replacement: a meta-analysis
    Rajiv Gandhi
    Surgery, University of Toronto, Toronto, Canada
    Int Orthop 33:593-7. 2009
    ..285 (95% confidence interval [CI]: 0.143 to 0.569; p < 0.001). We conclude that navigation in hip arthroplasty improves the precision of acetabular cup placement by decreasing the number of outliers from the desired alignment...
  21. doi request reprint Microarray analysis of the infrapatellar fat pad in knee osteoarthritis: relationship with joint inflammation
    Rajiv Gandhi
    Toronto Western Hospital, East Wing 1 439, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada
    J Rheumatol 38:1966-72. 2011
    ..To examine differences in genes involved in fat metabolism, energy homeostasis, adipogenesis, and inflammation between endstage and early-stage knee osteoarthritis (OA) infrapatellar fat pads (IFP)...
  22. ncbi request reprint Ethnicity and patient's perception of risk in joint replacement surgery
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 35:1664-7. 2008
    ..Despite much evidence showing racial disparities in the use of surgical procedures, it is unknown whether ethnicity affects perception of surgical risk...
  23. doi request reprint Predicting the longer-term outcomes of total hip replacement
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 37:2573-7. 2010
    ..The objective of this study was to identify the patient-level predictors (age, sex, body mass index, mental health, and comorbidity) for a sustained functional outcome at a minimum 1 year of followup after total hip replacement (THR)...
  24. doi request reprint High-flexion implants in primary total knee arthroplasty: a meta-analysis
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Canada
    Knee 16:14-7. 2009
    ..We asked whether a high-flexion design implant improves patient functional outcomes or range of motion (ROM) after primary knee arthroplasty...
  25. pmc Quantifying the pain experience in hip and knee osteoarthritis
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, Ontario, Canada
    Pain Res Manag 15:224-8. 2010
    ..Furthermore, the impact that mental health symptoms and catastrophizing had on these scales was investigated...
  26. doi request reprint The synovial fluid adiponectin-leptin ratio predicts pain with knee osteoarthritis
    Rajiv Gandhi
    Division of Orthopaedic Surgery, Toronto Western Hospital, University Health Network, Department of Surgery, University of Toronto, 399 Bathurst Street, East Wing 1 439, Toronto, ON, M5T 2S8, Canada
    Clin Rheumatol 29:1223-8. 2010
    ..03) but not the WOMAC pain scale (p=0.77). A greater A/L ratio was associated with less pain with severe knee OA and this metabolic pathway may represent a target for novel therapeutics...
  27. doi request reprint Prevalence of clinically significant improvement following total knee replacement
    Khalid Alzahrani
    Division of Orthopedic Surgery, Toronto Western Hospital, Toronto, Ontario M5T 2S8, Canada
    J Rheumatol 38:753-9. 2011
    ..The purpose of our retrospective cohort study was to determine the prevalence of patients showing no clinically important improvement 1 year after TKR, and patient factors that may predict this outcome...
  28. ncbi request reprint Predictive risk factors for stiff knees in total knee arthroplasty
    Rajiv Gandhi
    Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
    J Arthroplasty 21:46-52. 2006
    ....
  29. doi request reprint Asian ethnicity and the prevalence of metabolic syndrome in the osteoarthritic total knee arthroplasty population
    Rajiv Gandhi
    Division of Orthopedic Surgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
    J Arthroplasty 25:416-9. 2010
    ..1-3.8; P = .03) times greater odds of MS as compared with those of other ethnicity. Metabolic syndrome is a risk factor for OA, and Asians demonstrate a greater prevalence of MS as compared with whites and blacks in this population...
  30. doi request reprint Topical application of tranexamic acid reduces postoperative blood loss in total knee arthroplasty: a randomized, controlled trial
    Jean Wong
    Department of Anesthesia, Toronto Western Hospital, University of Toronto, 2MC 434, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada
    J Bone Joint Surg Am 92:2503-13. 2010
    ..The objective of the present trial was to assess the efficacy and safety of the topical application of tranexamic acid on postoperative blood loss in patients undergoing primary unilateral total knee arthroplasty with cement...
  31. doi request reprint Inpatient compared with home-based rehabilitation following primary unilateral total hip or knee replacement: a randomized controlled trial
    Nizar N Mahomed
    Toronto Western Hospital, University Health Network, 399 Bathurst Street, East Wing 1 435, Toronto, ON M5T 2S8, Canada
    J Bone Joint Surg Am 90:1673-80. 2008
    ..We evaluated the effectiveness and cost of care of home-based compared with inpatient rehabilitation following primary total hip or knee joint replacement...
  32. pmc Does patient perception of alignment affect total knee arthroplasty outcome?
    Rajiv Gandhi
    Hamilton Arthroplasty Group, Hamilton Health Sciences Henderson Hospital, affiliated with the Faculty of Health Sciences, McMaster University, Hamilton, Ont, Canada
    Can J Surg 50:181-6. 2007
    ..We carried out a prospective survey to determine patient perception of limb alignment after total knee arthroplasty (TKA) and whether level of satisfaction with alignment affects clinical outcome...
  33. doi request reprint Multiple joint involvement in total knee replacement for osteoarthritis: Effects on patient-reported outcomes
    A V Perruccio
    Toronto Western Hospital and University of Toronto, 399 Bathurst Street, Toronto, Ontario, Canada
    Arthritis Care Res (Hoboken) 64:838-46. 2012
    ....
  34. ncbi request reprint Patient expectations predict greater pain relief with joint arthroplasty
    Rajiv Gandhi
    Toronto Western Hospital, Division of Orthopedic Surgery, Toronto, Ontario, Canada
    J Arthroplasty 24:716-21. 2009
    ..05). Patient expectation of pain relief after joint arthroplasty is an important predictor of outcomes at 1 year...
  35. doi request reprint Antibiotic bone cement and the incidence of deep infection after total knee arthroplasty
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Toronto, ON, Canada
    J Arthroplasty 24:1015-8. 2009
    ..84). Antibiotic-laden bone cement did not reduce the incidence of deep infection following primary total knee arthroplasty at 1-year follow-up...
  36. ncbi request reprint Fractures at the tip of long-stem prostheses used for revision hip arthroplasty
    Paul Zalzal
    Department of Orthopaedic Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada
    J Arthroplasty 18:741-5. 2003
    ..A bowed stem of that length may be a safer alternative. Otherwise, a shorter, straight stem may reduce the risk of complications at the stem tip...
  37. ncbi request reprint Incidence and timing of myocardial infarction after total joint arthroplasty
    Rajiv Gandhi
    Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
    J Arthroplasty 21:874-7. 2006
    ..Our data cautions against hospital discharge within 3 days of surgery...
  38. doi request reprint Complications following hip arthroscopy: a systematic review and meta-analysis
    M Kowalczuk
    Division of Orthopaedic Surgery, Department of Surgery, McMaster University, 1200 Main Street West, Hamilton, ON, Canada
    Knee Surg Sports Traumatol Arthrosc 21:1669-75. 2013
    ..The primary goal of this study is to determine the complication rate associated with hip arthroscopy in the literature...
  39. doi request reprint Predicting return to work following treatment of chronic pain disorder
    H Hamer
    Altum Health, Toronto Western Hospital, University Health Network, Ontario M5T 2S8, Canada
    Occup Med (Lond) 63:253-9. 2013
    ..The care of injured workers with chronic pain remains an important public health issue given its increasing prevalence. The consequences often include loss of self-esteem and stress in family relationships...
  40. doi request reprint Hydroxyapatite coated femoral stems in primary total hip arthroplasty: a meta-analysis
    Rajiv Gandhi
    Division of Orthopedic Surgery, University of Toronto, Ontario, Canada
    J Arthroplasty 24:38-42. 2009
    ..072 (95% CI: -0.062 to 0.206), P = .293. The results of this study demonstrate that there are no clinical benefits in the use of HA/porous coating over porous coating alone in primary hip arthroplasty...
  41. doi request reprint Simple decompression versus anterior subcutaneous and submuscular transposition of the ulnar nerve for cubital tunnel syndrome: a meta-analysis
    Sheina A Macadam
    Department of Surgery, Division of Plastic and Reconstructive Surgery, University of British Columbia, Vancouver, British Columbia, Canada
    J Hand Surg Am 33:1314.e1-12. 2008
    ..The purpose of this meta-analysis was to compare simple decompression to anterior transposition of the ulnar nerve for the treatment of this condition, using comparative trials and randomized controlled trials...
  42. doi request reprint A randomized trial of hydroxyapatite-coated femoral stems in total hip arthroplasty: a 13-year follow-up
    Dan Camazzola
    Division of Orthopedic Surgery, York Central Hospital, ON, Canada
    J Arthroplasty 24:33-7. 2009
    ..This study suggests there is no clinical advantage to the use of a hydroxyapatite coating on the femoral component of this design for primary total hip arthroplasty...
  43. pmc In-hospital mortality following hip fracture care in southern Ontario
    Khalid Alzahrani
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Can J Surg 53:294-8. 2010
    ..The incidence of hip fractures is increasing within the aging population. We investigated the overall rate of in-hospital mortality following hip fracture and how this mortality rate compares across academic and community hospitals...
  44. doi request reprint Total knee arthroplasty and Crigler-Najjar syndrome: a case report
    David Walmsley
    Division of Orthopedic Surgery, Department of Surgery, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
    Knee 17:252-4. 2010
    ..A literature review and intra-operative observations provide insight into the possible relationship between hyperbilirubinemia and osteoarthritis as well as the peri-operative considerations to be made for this group of patients...