Research Topics
Species | Emma E FrostSummaryAffiliation: University of Manitoba Country: Canada Publications
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Detail Information
Publications
Initiation of oligodendrocyte progenitor cell migration by a PDGF-A activated extracellular regulated kinase (ERK) signaling pathwayEmma E Frost
Department of Pathology, University of Manitoba, JBRC401, 727 McDermot Avenue, Winnipeg, MB, Canada, R3E 3P5
Neurochem Res 34:169-81. 2009..These findings indicate PDGF-A may act to mobilize OP cells that then respond to distinct directional signals to distribute appropriately within the CNS...
The role of dorsal root ganglia activation and brain-derived neurotrophic factor in multiple sclerosisWenjun Zhu
Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada
J Cell Mol Med 16:1856-65. 2012..The anterograde transport of DRG-derived BDNF to the spinal cord may have potential implications in facilitating central myelin repair and neuroprotection...
CXCL1 regulation of oligodendrocyte progenitor cell migration is independent of calcium signalingParvez Vora
Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada
Exp Neurol 236:259-67. 2012..Our results provide intriguing results relevant to specific aspects of patterning of white matter tracts in the central nervous system, and may further the understanding of tissue remodeling seen during disease-related processes...
Differential effects of growth factors on oligodendrocyte progenitor migrationParvez Vora
Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada
Eur J Cell Biol 90:649-56. 2011..In addition, ERK activation alone is not sufficient to induce OP migration. The current research supports the involvement of the non-ERK mediated signaling pathway in OP migration...
Toxic effect of blood components on perinatal rat subventricular zone cells and oligodendrocyte precursor cell proliferation, differentiation and migration in culturePackiasamy A R Juliet
Department of Pathology, University of Manitoba and Manitoba Institute of Child Health Research, Winnipeg, Canada
J Neurochem 109:1285-99. 2009..We conclude that soluble blood components, particularly thrombin, have an adverse effect on maturing SVZ cells and OPC derived from newborn rat brain...
