Paul R Fortin

Summary

Affiliation: University Health Network
Country: Canada

Publications

  1. doi request reprint Steroid-sparing effects of methotrexate in systemic lupus erythematosus: a double-blind, randomized, placebo-controlled trial
    Paul R Fortin
    University Health Network, Toronto Western Hospital, Toronto Western Research Institute, Ontario, Canada
    Arthritis Rheum 59:1796-804. 2008
  2. doi request reprint Glomerular filtration rate predicts arterial events in women with systemic lupus erythematosus
    Wendy Zhang
    Arthritis Centre of Excellence, Toronto Western Hospital, Toronto, ON M5T 2S8, Canada
    Rheumatology (Oxford) 50:799-805. 2011
  3. pmc Evaluation of clinical outcomes and renal vascular pathology among patients with lupus
    Claire Barber
    Division of Rheumatology, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Clin J Am Soc Nephrol 7:757-64. 2012
  4. doi request reprint Neuropsychiatric lupus: the prevalence and autoantibody associations depend on the definition: results from the 1000 faces of lupus cohort
    Alan M Borowoy
    Western University, London, Ontario, Canada
    Semin Arthritis Rheum 42:179-85. 2012
  5. doi request reprint The use of micronutrient supplements is not associated with better quality of life and disease activity in Canadian patients with systemic lupus erythematosus
    Elaheh Aghdassi
    University Health Network, Toronto Western Hospital, Toronto, Canada
    J Rheumatol 37:87-90. 2010
  6. doi request reprint Prevalence and risk factors for liver biochemical abnormalities in Canadian patients with systemic lupus erythematosus
    Darryl Huang
    Division of Health Care and Outcome Research, Toronto Western Research Institute, Toronto, Ontario, Canada
    J Rheumatol 39:254-61. 2012
  7. doi request reprint Increased expression of B cell activation factor supports the abnormal expansion of transitional B cells in systemic lupus erythematosus
    Carolina Landolt-Marticorena
    Arthritis Centre of Excellence, Division of Genetics and Development, and the Division of Health Care and Outcomes Research, Toronto Western Hospital Research Institute, University Health Network, Toronto, Ontario, Canada
    J Rheumatol 38:642-51. 2011
  8. doi request reprint Healthcare cost and loss of productivity in a Canadian population of patients with and without lupus nephritis
    Elaheh Aghdassi
    Department of Medicine, Division of Rheumatology, University Health Network, University of Toronto, Canada
    J Rheumatol 38:658-66. 2011
  9. doi request reprint Thrombovascular events affect quality of life in patients with systemic lupus erythematosus
    Amaris K Balitsky
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 38:1017-9. 2011
  10. doi request reprint Serum albumin as a marker for disease activity in patients with systemic lupus erythematosus
    Jonathan Yip
    Division of Health Care and Outcome Research, Toronto Western Research Institute, Toronto, Ontario, Canada
    J Rheumatol 37:1667-72. 2010

Collaborators

Detail Information

Publications36

  1. doi request reprint Steroid-sparing effects of methotrexate in systemic lupus erythematosus: a double-blind, randomized, placebo-controlled trial
    Paul R Fortin
    University Health Network, Toronto Western Hospital, Toronto Western Research Institute, Ontario, Canada
    Arthritis Rheum 59:1796-804. 2008
    ..To assess the potential benefits of methotrexate in patients with systemic lupus erythematosus (SLE)...
  2. doi request reprint Glomerular filtration rate predicts arterial events in women with systemic lupus erythematosus
    Wendy Zhang
    Arthritis Centre of Excellence, Toronto Western Hospital, Toronto, ON M5T 2S8, Canada
    Rheumatology (Oxford) 50:799-805. 2011
    ..To determine whether renal function predicts the development of cardiovascular disease and other arterial vascular events in patients with SLE...
  3. pmc Evaluation of clinical outcomes and renal vascular pathology among patients with lupus
    Claire Barber
    Division of Rheumatology, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Clin J Am Soc Nephrol 7:757-64. 2012
    ..The objective of this study was to determine the clinical significance of renal vascular lesions in lupus nephritis...
  4. doi request reprint Neuropsychiatric lupus: the prevalence and autoantibody associations depend on the definition: results from the 1000 faces of lupus cohort
    Alan M Borowoy
    Western University, London, Ontario, Canada
    Semin Arthritis Rheum 42:179-85. 2012
    ..The (ever) prevalence of neuropsychiatric systemic lupus erythematosus (NPSLE) can vary widely depending on the definition used. We determined the prevalence of NPSLE in 1000 Faces of Lupus, a large multicenter Canadian cohort...
  5. doi request reprint The use of micronutrient supplements is not associated with better quality of life and disease activity in Canadian patients with systemic lupus erythematosus
    Elaheh Aghdassi
    University Health Network, Toronto Western Hospital, Toronto, Canada
    J Rheumatol 37:87-90. 2010
    ..Associations between the use of micronutrient supplements (MS) and disease activity, quality of life (QOL), and healthcare resource utilization were studied in a Canadian population of patients with systemic lupus erythematosus (SLE)...
  6. doi request reprint Prevalence and risk factors for liver biochemical abnormalities in Canadian patients with systemic lupus erythematosus
    Darryl Huang
    Division of Health Care and Outcome Research, Toronto Western Research Institute, Toronto, Ontario, Canada
    J Rheumatol 39:254-61. 2012
    ....
  7. doi request reprint Increased expression of B cell activation factor supports the abnormal expansion of transitional B cells in systemic lupus erythematosus
    Carolina Landolt-Marticorena
    Arthritis Centre of Excellence, Division of Genetics and Development, and the Division of Health Care and Outcomes Research, Toronto Western Hospital Research Institute, University Health Network, Toronto, Ontario, Canada
    J Rheumatol 38:642-51. 2011
    ..To examine the relationship between interferon-α (IFN-α) and dysregulation of B cell activation factor (BAFF) and specific B cell phenotypes in systemic lupus erythematosus (SLE)...
  8. doi request reprint Healthcare cost and loss of productivity in a Canadian population of patients with and without lupus nephritis
    Elaheh Aghdassi
    Department of Medicine, Division of Rheumatology, University Health Network, University of Toronto, Canada
    J Rheumatol 38:658-66. 2011
    ..To compare the healthcare cost and loss of productivity in patients with systemic lupus erythematosus (SLE) with (LN) and without lupus nephritis (lupus nephritis-negative, LNN)...
  9. doi request reprint Thrombovascular events affect quality of life in patients with systemic lupus erythematosus
    Amaris K Balitsky
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 38:1017-9. 2011
    ..To compare health-related quality of life (HRQOL) of patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) with and without previous thrombovascular events (TE)...
  10. doi request reprint Serum albumin as a marker for disease activity in patients with systemic lupus erythematosus
    Jonathan Yip
    Division of Health Care and Outcome Research, Toronto Western Research Institute, Toronto, Ontario, Canada
    J Rheumatol 37:1667-72. 2010
    ..There is currently no clinical "gold standard" in the assessment of disease activity in SLE...
  11. doi request reprint Peripheral neuropathy in patients with systemic lupus erythematosus
    Brandusa Florica
    Division of Rheumatology, Department of Medicine, The University Health Network and University of Toronto, Toronto, Ontario, Canada
    Semin Arthritis Rheum 41:203-11. 2011
    ....
  12. doi request reprint Altered expression of TNF-alpha signaling pathway proteins in systemic lupus erythematosus
    Lang jing Zhu
    Arthritis Centre of Excellence and Toronto Western Hospital Research Institute, Divisions of Genetics and Development and Population Health, Toronto Western Hospital, Toronto, Ontario, Canada
    J Rheumatol 37:1658-66. 2010
    ..To investigate the expression of tumor necrosis factor receptors (TNFR1 and TNFR2) and adapter proteins (TRADD, RIP, and TRAF2) in peripheral blood mononuclear cell (PBMC) subsets from patients with systemic lupus erythematosus (SLE)...
  13. doi request reprint Work disability in systemic lupus erythematosus is prevalent and associated with socio-demographic and disease related factors
    K Baker
    Meds 2010, School of Medicine, Queen s University, Kingston, Ontario, Canada
    Lupus 18:1281-8. 2009
    ..Socio-demographic factors, co-morbidities (fibromyalgia and fatigue) and disease related factors were strongly associated with WD. We cannot determine cause and effect as the study was cross-sectional...
  14. ncbi request reprint Incidence rates of arterial and venous thrombosis after diagnosis of systemic lupus erythematosus
    Zhaleh Shariati Sarabi
    Toronto Western Hospital, University Health Network Research Institute, University of Toronto, Toronto, Ontario, Canada
    Arthritis Rheum 53:609-12. 2005
  15. doi request reprint Alterations in circulating fatty acid composition in patients with systemic lupus erythematosus: a pilot study
    Elaheh Aghdassi
    Division of Health Care and Outcome Research, Toronto Western Research Institute, Ontario, Canada
    JPEN J Parenter Enteral Nutr 35:198-208. 2011
    ..Circulating fatty acids (FAs) may play a role in the disease pathogenesis of patients with systemic lupus erythematosus (SLE)...
  16. ncbi request reprint Organ manifestations influence differently the responsiveness of 2 lupus disease activity measures, according to patients' or physicians' evaluations of recent lupus activity
    Erika R Chang
    The Arthritis Centre of Excellence, Toronto, Ontario, Canada
    J Rheumatol 29:2350-8. 2002
    ....
  17. doi request reprint The protective effect of antimalarial drugs on thrombovascular events in systemic lupus erythematosus
    Hyejung Jung
    McMaster University, Hamilton, Ontario, Canada, and University of Toronto, Toronto, Ontario, Canada
    Arthritis Rheum 62:863-8. 2010
    ..This study was conducted to assess whether exposure to antimalarial drugs is associated with a decrease in thrombovascular events (TEs) in patients with SLE...
  18. doi request reprint The early protective effect of hydroxychloroquine on the risk of cumulative damage in patients with systemic lupus erythematosus
    Pooneh S Akhavan
    Division of Rheumatology, Department of Medicine, University of Toronto, Ontario, Canada
    J Rheumatol 40:831-41. 2013
    ..To assess whether hydroxychloroquine (HCQ) prevents early damage in patients with systemic lupus erythematosus (SLE)...
  19. doi request reprint Ten-year absolute fracture risk and hip bone strength in Canadian women with systemic lupus erythematosus
    Jennifer J Y Lee
    Division of Health Care and Outcome Research, Toronto Western Research Institute, Toronto, Ontario, Canada
    J Rheumatol 39:1378-84. 2012
    ....
  20. ncbi request reprint Should tetracycline treatment be used more extensively for rheumatoid arthritis? Metaanalysis demonstrates clinical benefit with reduction in disease activity
    Millicent Stone
    Division of Rheumatology, Department of Medicine, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada
    J Rheumatol 30:2112-22. 2003
    ..To compare the effectiveness of tetracycline antibiotics versus control (placebo or conventional treatment) in rheumatoid arthritis (RA) for the reduction of disease activity as defined by American College of Rheumatology criteria...
  21. ncbi request reprint Timing of total joint replacement affects clinical outcomes among patients with osteoarthritis of the hip or knee
    Paul R Fortin
    University of Toronto, Toronto, Ontario, Canada
    Arthritis Rheum 46:3327-30. 2002
    ..To determine the predictors of outcome in patients with osteoarthritis 2 years after receiving total hip or knee replacement...
  22. ncbi request reprint Association between serum total cholesterol level and renal outcome in systemic lupus erythematosus
    Annaliese Tisseverasinghe
    Arthritis Centre of Excellence, University Health Network, Toronto Western Hospital, 399 Bathurst Street, MP 10 304, Toronto, Ontario M5T 2S8, Canada
    Arthritis Rheum 54:2211-9. 2006
    ..To determine whether an elevated serum total cholesterol level in a first-available sample obtained at a systemic lupus erythematosus (SLE) clinic is associated with worse renal outcome in patients with SLE...
  23. doi request reprint Systemic lupus erythematosus disease activity index 2000 responder index-50: a reliable index for measuring improvement in disease activity
    Zahi Touma
    Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario, Canada
    J Rheumatol 38:868-73. 2011
    ....
  24. pmc Molecular markers of injury in kidney biopsy specimens of patients with lupus nephritis
    Heather N Reich
    University Health Network and University of Toronto, Toronto, Ontario, Canada
    J Mol Diagn 13:143-51. 2011
    ....
  25. doi request reprint A hot spot for systemic lupus erythematosus, but not for psoriatic arthritis, identified by spatial analysis suggests an interaction between ethnicity and place of residence
    Mustafa Al-Maini
    Toronto Western Research Institute, Toronto, Ontario, Canada
    Arthritis Rheum 65:1579-85. 2013
    ..To describe the spatial distribution of incident cases of systemic lupus erythematosus (SLE) using geographic information systems (GIS)...
  26. doi request reprint Work disability in systemic lupus erythematosus
    Ali M Al Dhanhani
    Toronto Western Hospital of The University Health Network, Toronto, Ontario, Canada
    Arthritis Rheum 61:378-85. 2009
    ..To determine the prevalence, accrual over time, and risk factors of work disability in patients with systemic lupus erythematosus (SLE)...
  27. ncbi request reprint Comparison of the responsiveness of lupus disease activity measures to changes in systemic lupus erythematosus activity relevant to patients and physicians
    Erika Chang
    The Arthritis Centre of Excellence, Division of Rheumatology, The Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Clin Epidemiol 55:488-97. 2002
    ..Only SLAM-R is responsive to changes important to patients. These differences may result from the inclusion of subjective SLE manifestations in SLAM-R...
  28. ncbi request reprint Expanded population of activated antigen-engaged cells within the naive B cell compartment of patients with systemic lupus erythematosus
    Nan Hua Chang
    Arthritis Centre of Excellence, Toronto Western Hospital Research Institute, and Department of Medicine, University of Toronto, Ontario, Canada
    J Immunol 180:1276-84. 2008
    ..Although controls also had IgD+IgMlowCD23+ cells, they were reduced in number and not activated. Thus, there is an altered response to Ig receptor engagement with self-Ags in lupus...
  29. doi request reprint Systematic review of validation studies of the use of administrative data to identify serious infections
    Claire Barber
    University Health Network, Toronto Western Research Institute, and University of Toronto, Toronto, Ontario, Canada
    Arthritis Care Res (Hoboken) 65:1343-57. 2013
    ..To conduct a systematic review of the literature on the validation of algorithms identifying infections in administrative data for future use in populations with rheumatic diseases...
  30. pmc Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity
    Joan Wither
    Arthritis Centre of Excellence, Division of Genetics and Development, Toronto Western Hospital Research Institute, University Health Network, Toronto, Ontario, Canada
    Arthritis Res Ther 10:R108. 2008
    ..Here, we used flow cytometry to investigate whether some of the immune abnormalities that are seen in the peripheral blood lymphocyte population of lupus patients are seen in their first-degree relatives...
  31. ncbi request reprint The importance of patient expectations in predicting functional outcomes after total joint arthroplasty
    Nizar N Mahomed
    Division of Orthopaedic Surgery, Toronto Western Hospital, University of Toronto, ON, Canada
    J Rheumatol 29:1273-9. 2002
    ..Multivariate regression models were used to evaluate the impact of expectations on outcomes...
  32. ncbi request reprint "What do you expect? You're just getting older": A comparison of perceived osteoarthritis-related and aging-related health experiences in middle- and older-age adults
    Monique A M Gignac
    Division of Outcomes and Health Care Research, Arthritis Community Research and Evaluation Unit, Toronto Western Research Institute, University of Toronto, Toronto, Ontario, Canada
    Arthritis Rheum 55:905-12. 2006
    ..Similarities and differences in health changes, the meaning of these changes, and their impact were examined...
  33. doi request reprint Posterior reversible encephalopathy syndrome: an emerging disease manifestation in systemic lupus erythematosus
    Claire E Barber
    Division of Rheumatology, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Semin Arthritis Rheum 41:353-63. 2011
    ..We describe 7 new cases of PRES in SLE patients that highlight some of the diagnostic and treatment dilemmas of this condition...
  34. ncbi request reprint Identification and characterization of an Xp22.33;Yp11.2 translocation causing a triplication of several genes of the pseudoautosomal region 1 in an XX male patient with severe systemic lupus erythematosus
    Pierre Chagnon
    University of Montreal, Montreal, Quebec, and Hospital for Sick Children, Toronto, Ontario, Canada
    Arthritis Rheum 54:1270-8. 2006
    ....
  35. ncbi request reprint Intravenous cyclophosphamide and high dose corticosteroids improve MRI lesions in demyelinating syndrome in systemic lupus erythematosus
    Felix K Leung
    Division of Rheumatology, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Rheumatol 30:1871-3. 2003
  36. ncbi request reprint Role of radiation therapy in patients with a diagnosis of both systemic lupus erythematosus and cancer
    Veronique Benk
    Sunnybrook Regional Cancer Center, Toronto, Ontario, Canada
    Arthritis Rheum 53:67-72. 2005
    ..To determine whether radiation therapy (RT) is denied to patients with lupus and cancer and whether RT causes unusual toxicity in those receiving it...