Valerie C Fleisch

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. doi Investigating regeneration and functional integration of CNS neurons: lessons from zebrafish genetics and other fish species
    Valerie C Fleisch
    Centre for Prions and Protein Folding Disease, University of Alberta, Edmonton, Alberta, Canada
    Biochim Biophys Acta 1812:364-80. 2011
  2. ncbi Evaluating the mutagenic activity of targeted endonucleases containing a Sharkey FokI cleavage domain variant in zebrafish
    Laura M Pillay
    Department of Biological Sciences, University of Alberta, Edmonton, Canada
    Zebrafish 10:353-64. 2013
  3. doi Targeted mutation of the gene encoding prion protein in zebrafish reveals a conserved role in neuron excitability
    Valerie C Fleisch
    Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada
    Neurobiol Dis 55:11-25. 2013
  4. doi A complex regulatory network of transcription factors critical for ocular development and disease
    Moulinath Acharya
    Department of Medical Genetics, University of Alberta, Edmonton, AB, Canada T6G 2H7
    Hum Mol Genet 20:1610-24. 2011
  5. doi Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies
    Ming Ye
    Department of Ophthalmology, University of Alberta, Edmonton, Canada
    Hum Mol Genet 19:287-98. 2010
  6. doi Parallel visual cycles in the zebrafish retina
    Valerie C Fleisch
    Centre for Prions, Protein Folding Disease, University of Alberta, Edmonton, Alberta, Canada
    Prog Retin Eye Res 29:476-86. 2010

Collaborators

Detail Information

Publications6

  1. doi Investigating regeneration and functional integration of CNS neurons: lessons from zebrafish genetics and other fish species
    Valerie C Fleisch
    Centre for Prions and Protein Folding Disease, University of Alberta, Edmonton, Alberta, Canada
    Biochim Biophys Acta 1812:364-80. 2011
    ..This article is part of a Special Issue entitled Zebrafish Models of Neurological Diseases...
  2. ncbi Evaluating the mutagenic activity of targeted endonucleases containing a Sharkey FokI cleavage domain variant in zebrafish
    Laura M Pillay
    Department of Biological Sciences, University of Alberta, Edmonton, Canada
    Zebrafish 10:353-64. 2013
    ..Notably, Sharkey ZFNs and TALENs do not generate increased toxicity-related defects or mortality. Our results present Sharkey ZFNs as an effective alternative to conventional ZFNs, but advise against the use of Sharkey TALENs...
  3. doi Targeted mutation of the gene encoding prion protein in zebrafish reveals a conserved role in neuron excitability
    Valerie C Fleisch
    Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada
    Neurobiol Dis 55:11-25. 2013
    ....
  4. doi A complex regulatory network of transcription factors critical for ocular development and disease
    Moulinath Acharya
    Department of Medical Genetics, University of Alberta, Edmonton, AB, Canada T6G 2H7
    Hum Mol Genet 20:1610-24. 2011
    ..We have therefore identified a functional link between three transcription factors, modulated by PAWR, which we propose underlies the similar ocular phenotypes and glaucoma pathology caused by mutations of these genes...
  5. doi Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies
    Ming Ye
    Department of Ophthalmology, University of Alberta, Edmonton, Canada
    Hum Mol Genet 19:287-98. 2010
    ..By demonstrating the pleiotropic effects of GDF3 mutation, these results extend the contribution of perturbed BMP signaling to human disease and potentially implicate multi-allelic inheritance of BMP variants in developmental disorders...
  6. doi Parallel visual cycles in the zebrafish retina
    Valerie C Fleisch
    Centre for Prions, Protein Folding Disease, University of Alberta, Edmonton, Alberta, Canada
    Prog Retin Eye Res 29:476-86. 2010
    ..This review summarizes the efforts made in zebrafish to gain a better understanding of the role of these two visual cycles for rod and cone photoreceptor chromophore recycling...