David N Fisman

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. doi request reprint Effectiveness and cost-effectiveness of pediatric rotavirus vaccination in British Columbia: a model-based evaluation
    David N Fisman
    Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    Vaccine 30:7601-7. 2012
  2. doi request reprint Seasonality of viral infections: mechanisms and unknowns
    D Fisman
    The Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
    Clin Microbiol Infect 18:946-54. 2012
  3. pmc Reactive strategies for containing developing outbreaks of pandemic influenza
    Sigrún Andradóttir
    H Milton Stewart School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA
    BMC Public Health 11:S1. 2011
  4. pmc Vaccination against 2009 pandemic H1N1 in a population dynamical model of Vancouver, Canada: timing is everything
    Jessica M Conway
    Division of Mathematical Modeling, University of British Columbia Centre for Disease Control, 655 West 12th Avenue, V5Z 4R4 Vancouver, British Columbia, Canada
    BMC Public Health 11:932. 2011
  5. pmc Estimation of the health impact and cost-effectiveness of influenza vaccination with enhanced effectiveness in Canada
    David N Fisman
    Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    PLoS ONE 6:e27420. 2011
  6. pmc Pertussis resurgence in Toronto, Canada: a population-based study including test-incidence feedback modeling
    David N Fisman
    Dalla Lana School of Public Health, University of Toronto, Canada
    BMC Public Health 11:694. 2011
  7. pmc Prevalence of and risk factors for quinolone-resistant Neisseria gonorrhoeae infection in Ontario
    Kaede V Ota
    Division of Microbiology, Pediatric Laboratory Medicine, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario
    CMAJ 180:287-90. 2009
  8. doi request reprint Why "winter" vomiting disease? Seasonality, hydrology, and Norovirus epidemiology in Toronto, Canada
    Amy L Greer
    Child Health Evaluative Sciences, The Research Institute of the Hospital for Sick Children, Toronto, ON, Canada
    Ecohealth 6:192-9. 2009
  9. pmc Epidemiology of invasive meningococcal disease with decreased susceptibility to penicillin in Ontario, Canada, 2000 to 2006
    Elizabeth M Brown
    Ontario Agency for Health Protection and Promotion, Public Health Laboratories, 81 Resources Road, Toronto, Ontario, Canada M9P 3T1
    Antimicrob Agents Chemother 54:1016-21. 2010
  10. doi request reprint The co-seasonality of pneumonia and influenza with Clostridium difficile infection in the United States, 1993-2008
    Kevin A Brown
    Dalla Lana School of Public Health, University of Toronto, Ontario, Canada
    Am J Epidemiol 178:118-25. 2013

Collaborators

Detail Information

Publications51

  1. doi request reprint Effectiveness and cost-effectiveness of pediatric rotavirus vaccination in British Columbia: a model-based evaluation
    David N Fisman
    Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    Vaccine 30:7601-7. 2012
    ..Two live rotavirus vaccines (RotaTeq(®) (Merck Frosst Canada Ltd.) and Rotarix™ (GlaxoSmithKline Inc.)), are now approved for use in Canada, but their economic attractiveness has not been evaluated in the Canadian context...
  2. doi request reprint Seasonality of viral infections: mechanisms and unknowns
    D Fisman
    The Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
    Clin Microbiol Infect 18:946-54. 2012
    ..However, numerous areas of uncertainty exist, making this an exciting area for future research...
  3. pmc Reactive strategies for containing developing outbreaks of pandemic influenza
    Sigrún Andradóttir
    H Milton Stewart School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA
    BMC Public Health 11:S1. 2011
    ..This experience suggests the need to explore the epidemiological and economic effectiveness of additional, reactive strategies for combating pandemic influenza...
  4. pmc Vaccination against 2009 pandemic H1N1 in a population dynamical model of Vancouver, Canada: timing is everything
    Jessica M Conway
    Division of Mathematical Modeling, University of British Columbia Centre for Disease Control, 655 West 12th Avenue, V5Z 4R4 Vancouver, British Columbia, Canada
    BMC Public Health 11:932. 2011
    ..We adapted a city-level contact network model to study different campaigns on influenza morbidity and mortality...
  5. pmc Estimation of the health impact and cost-effectiveness of influenza vaccination with enhanced effectiveness in Canada
    David N Fisman
    Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    PLoS ONE 6:e27420. 2011
    ..The health and economic impact of such vaccines in the Canadian population are uncertain...
  6. pmc Pertussis resurgence in Toronto, Canada: a population-based study including test-incidence feedback modeling
    David N Fisman
    Dalla Lana School of Public Health, University of Toronto, Canada
    BMC Public Health 11:694. 2011
    ..We evaluated pertussis trends in Toronto using all available specimen data, which allowed us to control for changing testing patterns and practices...
  7. pmc Prevalence of and risk factors for quinolone-resistant Neisseria gonorrhoeae infection in Ontario
    Kaede V Ota
    Division of Microbiology, Pediatric Laboratory Medicine, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario
    CMAJ 180:287-90. 2009
    ..We sought to determine its prevalence in the province of Ontario and to investigate risk factors for quinolone-resistant N. gonorrhoeae infection in a Canadian setting...
  8. doi request reprint Why "winter" vomiting disease? Seasonality, hydrology, and Norovirus epidemiology in Toronto, Canada
    Amy L Greer
    Child Health Evaluative Sciences, The Research Institute of the Hospital for Sick Children, Toronto, ON, Canada
    Ecohealth 6:192-9. 2009
    ..We hypothesize that the reservoir may be maintained through the discharge of wastewater containing virus particles; wintertime seasonality may be explained by enhanced viral persistence at low temperatures...
  9. pmc Epidemiology of invasive meningococcal disease with decreased susceptibility to penicillin in Ontario, Canada, 2000 to 2006
    Elizabeth M Brown
    Ontario Agency for Health Protection and Promotion, Public Health Laboratories, 81 Resources Road, Toronto, Ontario, Canada M9P 3T1
    Antimicrob Agents Chemother 54:1016-21. 2010
    ..In contrast to trends of the 1990s, the incidence of IMD with DSP was stable in Ontario between 2000 and 2006. In Ontario, the serogroup rather than the penicillin MIC is the microbiological parameter most predictive of mortality...
  10. doi request reprint The co-seasonality of pneumonia and influenza with Clostridium difficile infection in the United States, 1993-2008
    Kevin A Brown
    Dalla Lana School of Public Health, University of Toronto, Ontario, Canada
    Am J Epidemiol 178:118-25. 2013
    ..073, 1.153). Future research could seek to understand which mediating pathways, including changes in broad-spectrum antibiotic prescribing and hospital crowding, are most responsible for the associated changes in incidence. ..
  11. doi request reprint Environmental determinants of campylobacteriosis risk in Philadelphia from 1994 to 2007
    Alexander N J White
    Faculty of Medicine, University of Toronto, Toronto, ON, Canada
    Ecohealth 6:200-8. 2009
    ....
  12. pmc Environmental exposures and invasive meningococcal disease: an evaluation of effects on varying time scales
    Laura M Kinlin
    Research Institute of the Hospital for Sick Children, Toronto, Ontario, Canada
    Am J Epidemiol 169:588-95. 2009
    ..The latter effect may be due to decreased pathogen survival or virulence and may explain the wintertime seasonality of IMD in temperate regions of North America...
  13. pmc New endemic Legionella pneumophila serogroup I clones, Ontario, Canada
    Nathalie Tijet
    Ontario Agency for Health Protection and Promotion, Toronto, Ontario, Canada
    Emerg Infect Dis 16:447-54. 2010
    ..These findings have general clinical implications for the study of Lp1 molecular evolution and for the identification of Lp1 circulating strains in North America...
  14. pmc Screen more or screen more often? Using mathematical models to inform syphilis control strategies
    Ashleigh R Tuite
    Dalla Lana School of Public Health, University of Toronto, Toronto, Canada
    BMC Public Health 13:606. 2013
    ..We examined the marginal effect of increased frequency versus increased coverage of screening on syphilis incidence in Toronto, Canada...
  15. pmc Respiratory virus infection and risk of invasive meningococcal disease in central Ontario, Canada
    Ashleigh R Tuite
    Dalla Lana School of Public Health, University of Toronto, Toronto, Canada
    PLoS ONE 5:e15493. 2010
    ....
  16. pmc Laboratory-based evaluation of legionellosis epidemiology in Ontario, Canada, 1978 to 2006
    Victoria Ng
    Child Health Evaluative Sciences, Research Institute of the Hospital for Sick Children, Toronto, Canada
    BMC Infect Dis 9:68. 2009
    ..We sought to provide a laboratory-based review of the epidemiology of legionellosis in Ontario over the past 3 decades, with a focus on changing rates of disease and species associated with legionellosis during that time period...
  17. pmc Optimal pandemic influenza vaccine allocation strategies for the Canadian population
    Ashleigh R Tuite
    Department of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    PLoS ONE 5:e10520. 2010
    ..We sought to determine optimal prioritization of vaccine distribution among different age and risk groups within the Canadian population, to minimize influenza-attributable morbidity and mortality...
  18. pmc Evaluation of coseasonality of influenza and invasive pneumococcal disease: results from prospective surveillance
    Stefan P Kuster
    Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, Canada
    PLoS Med 8:e1001042. 2011
    ..We aimed to investigate the relationship between influenza infection and IPD in Ontario, Canada, using several complementary methodological tools...
  19. pmc The role of cellular immunity in influenza H1N1 population dynamics
    Venkata R Duvvuri
    Centre for Disease Modelling, York University, Toronto, Ontario
    BMC Infect Dis 12:329. 2012
    ..Whether, and to what extent, the effect of this self-protective mechanism can be captured in the population dynamics of an influenza epidemic has not been addressed...
  20. doi request reprint Rapid identification of herd effects with the introduction of serogroup C meningococcal conjugate vaccine in Ontario, Canada, 2000-2006
    Laura M Kinlin
    The Research Institute of the Hospital for Sick Children, Toronto, Ontario, Canada The University of Toronto, Toronto, Ontario, Canada
    Vaccine 27:1735-40. 2009
    ..These apparent dramatic effects of conjugate C vaccine (both direct and indirect) may be important in the implementation and evaluation of vaccine policy in other jurisdictions...
  21. doi request reprint The laboratory impact of changing syphilis screening from the rapid-plasma reagin to a treponemal enzyme immunoassay: a case-study from the Greater Toronto Area
    Sharmistha Mishra
    Division of Infectious Diseases, University of Toronto, and Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, Canada
    Sex Transm Dis 38:190-6. 2011
    ..We sought to understand the consequences of this change on laboratory results and testing patterns with a population-based retrospective study of laboratory-based diagnoses of syphilis...
  22. doi request reprint The Philadelphia High-School STD Screening Program: key insights from dynamic transmission modeling
    David N Fisman
    Research Institute of the Hospital for Sick Children, Toronto, Ontario, Canada
    Sex Transm Dis 35:S61-5. 2008
    ..We sought to assess program cost-effectiveness in a manner that allowed us to quantify the impact of including males students in the screened population...
  23. doi request reprint Number-needed-to-vaccinate calculations: fallacies associated with exclusion of transmission
    Ashleigh R Tuite
    Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto and Decision Centre for Infectious Disease Epidemiology DeCIDE, 155 College Street, Toronto, Ontario, Canada
    Vaccine 31:973-8. 2013
    ..e., risk of infection in susceptible individuals). We postulated that such calculations could produce profoundly biased estimates of vaccine attractiveness...
  24. pmc The impact of infection on population health: results of the Ontario burden of infectious diseases study
    Jeffrey C Kwong
    Institute for Clinical Evaluative Sciences, Toronto, Canada
    PLoS ONE 7:e44103. 2012
    ..We sought to quantify the contribution of a wide range of infectious diseases to the overall infectious disease burden in a high-income setting...
  25. doi request reprint Use of models to identify cost-effective interventions: pertussis vaccination for pediatric health care workers
    Amy L Greer
    Public Health Agency of Canada, 180 Queen St W, 11th Floor, Toronto, Ontario, Canada M5V 3L7
    Pediatrics 128:e591-9. 2011
    ..We sought to evaluate the health-economic attractiveness of a diphtheria-tetanus-acellular pertussis booster vaccination program for health care workers in a pediatric intensive care setting...
  26. doi request reprint Core groups, antimicrobial resistance and rebound in gonorrhoea in North America
    Christina H Chan
    Division of Epidemiology, Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, 155 College Street, Room 678, Toronto, Ontario, Canada M5T 3M7
    Sex Transm Infect 88:200-4. 2012
    ..Surveillance data suggest that incidence has increased in recent years after initially falling in the face of intensified control efforts...
  27. doi request reprint Going with the flow: legionellosis risk in Toronto, Canada is strongly associated with local watershed hydrology
    Victoria Ng
    Research Institute of the Hospital for Sick Children, Toronto, Canada
    Ecohealth 5:482-90. 2008
    ..These observations suggest testable hypotheses for future empiric studies...
  28. doi request reprint Cholera, canals, and contagion: Rediscovering Dr. Beck's report
    Ashleigh R Tuite
    Dalla Lana School of Public Health, University of Toronto, Room 678, 155 College Street, Toronto, Ontario, Canada M5T 3M7
    J Public Health Policy 32:320-33. 2011
    ..We show that these themes continue to serve as obstacles to innovation in medical and public health practice today...
  29. doi request reprint Estimation of the burden of disease and costs of genital Chlamydia trachomatis infection in Canada
    Ashleigh R Tuite
    Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    Sex Transm Dis 39:260-7. 2012
    ..Rates of Chlamydia trachomatis (CT) infection in Canada have been increasing since the mid-1990s. We sought to estimate the burden of CT in this population...
  30. pmc Estimated epidemiologic parameters and morbidity associated with pandemic H1N1 influenza
    Ashleigh R Tuite
    Research Institute of the Hospital for Sick Children, and the Dalla Lana School of Public Health, Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario
    CMAJ 182:131-6. 2010
    ..We sought to estimate epidemiologic parameters for pandemic H1N1 influenza using data from initial reports of laboratory-confirmed cases...
  31. doi request reprint Keeping vulnerable children safe from pertussis: preventing nosocomial pertussis transmission in the neonatal intensive care unit
    Amy L Greer
    Child Health Evaluative Sciences, Research Institute of the Hospital for Sick Children, Toronto, Ontario, Canada
    Infect Control Hosp Epidemiol 30:1084-9. 2009
    ..To examine the impact of different acellular pertussis booster vaccination strategies on the probability of a nosocomial pertussis outbreak occurring and the distribution of outbreak sizes observed for each intervention strategy...
  32. pmc Meta-analysis of antibiotics and the risk of community-associated Clostridium difficile infection
    Kevin A Brown
    Epidemiology Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    Antimicrob Agents Chemother 57:2326-32. 2013
    ..Avoidance of high-risk antibiotics (such as clindamycin, CMCs, and fluoroquinolones) in favor of lower-risk antibiotics (such as penicillins, macrolides, and tetracyclines) may help reduce the incidence of CDI...
  33. doi request reprint Linking antimicrobial prescribing to antimicrobial resistance in the ICU: before and after an antimicrobial stewardship program
    Amy Hurford
    The Fields Institute for Research in Mathematical Sciences, Toronto, ON, Canada
    Epidemics 4:203-10. 2012
    ....
  34. pmc Of gastro and the gold standard: evaluation and policy implications of norovirus test performance for outbreak detection
    David N Fisman
    Division of Epidemiology and Surveillance, Ontario Agency for Health Protection and Promotion, Toronto, Canada
    J Transl Med 7:23. 2009
    ..Identification of NVG is complicated by the non-culturable nature of this virus, and the absence of a diagnostic gold standard makes traditional evaluation of test characteristics problematic...
  35. doi request reprint Derivation and validation of a clinical prediction rule for nosocomial pneumonia after coronary artery bypass graft surgery
    Laura M Kinlin
    Research Institute of the Hospital for Sick Children, Toronto, Ontario, Canada
    Clin Infect Dis 50:493-501. 2010
    ..We sought to develop a prediction rule for pneumonia after coronary artery bypass grafting (CABG), a common surgical procedure...
  36. doi request reprint Spectrum bias and loss of statistical power in discordant couple studies of sexually transmitted infections
    Ashleigh R Tuite
    Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario, Canada
    Sex Transm Dis 38:50-6. 2011
    ..Discordant couple studies are frequently used to evaluate preventive interventions for sexually transmitted infections (STI). This study design may be vulnerable to spectrum bias when transmission risk is heterogeneous...
  37. doi request reprint Use of gloves and reduction of risk of injury caused by needles or sharp medical devices in healthcare workers: results from a case-crossover study
    Laura M Kinlin
    Research Institute of the Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Infect Control Hosp Epidemiol 31:908-17. 2010
    ..We evaluated factors associated with gloving practices and identified associations between gloving practices and sharps-injury risk...
  38. pmc Optimal pandemic influenza vaccine allocation strategies for the canadian population
    Ashleigh Tuite
    Dalla Lana School of Public Health, University of Toronto Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada and Public Health Agency of Canada
    PLoS Curr 2:RRN1144. 2010
    ..Vaccination may significantly reduce influenza-attributable morbidity and mortality, but the benefits are dependent on epidemic dynamics, time for program roll-out, and vaccine uptake...
  39. pmc An IDEA for Short Term Outbreak Projection: Nearcasting Using the Basic Reproduction Number
    David N Fisman
    the Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada The Decision Centre for Infectious Disease Epidemiology DeCIDE, Toronto, Ontario, Canada
    PLoS ONE 8:e83622. 2013
    ..Here we develop a mathematical model to aid public health authorities in tracking the expansion and contraction of outbreaks with explicit representation of factors (other than population immunity) that may slow epidemic growth...
  40. pmc Historical epidemiology of the second cholera pandemic: relevance to present day disease dynamics
    Christina H Chan
    Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    PLoS ONE 8:e72498. 2013
    ....
  41. doi request reprint The ABC of terms used in mathematical models of infectious diseases
    Sharmistha Mishra
    Division of Infectious Diseases, St Michael s Hospital, University of Toronto, Toronto, Canada
    J Epidemiol Community Health 65:87-94. 2011
    ....
  42. pmc Health-related quality of life in Parkinson disease: correlation between Health Utilities Index III and Unified Parkinson's Disease Rating Scale (UPDRS) in U.S. male veterans
    Galit Kleiner-Fisman
    Department of Neurology, Baycrest Geriatric Hospital, Toronto, Ontario, Canada
    Health Qual Life Outcomes 8:91. 2010
    ....
  43. doi request reprint Incidence and treatment outcomes of pharyngeal Neisseria gonorrhoeae and Chlamydia trachomatis infections in men who have sex with men: a 13-year retrospective cohort study
    Kaede V Ota
    The Hospital for Sick Children, Ontario Agency for Health Protection and Promotion, Toronto, Ontario, Canada
    Clin Infect Dis 48:1237-43. 2009
    ..This study investigated the incidence and treatment outcomes of pharyngeal Neisseria gonorrhoeae and Chlamydia trachomatis cases at a Canadian clinic that mainly serves men who have sex with men...
  44. doi request reprint Cholera epidemic in Haiti, 2010: using a transmission model to explain spatial spread of disease and identify optimal control interventions
    Ashleigh R Tuite
    Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario, Canada
    Ann Intern Med 154:593-601. 2011
    ..Haiti is in the midst of a cholera epidemic. Surveillance data for formulating models of the epidemic are limited, but such models can aid understanding of epidemic processes and help define control strategies...
  45. pmc Is a Mass Immunization Program for Pandemic (H1N1) 2009 Good Value for Money? Early Evidence from the Canadian Experience
    Beate Sander
    Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada University of Guelph Dalla Lana School of Public Health, University of Toronto Sunnybrook Hospital, The University of Toronto Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada Department of Laboratory Medicine and Pathobiology, University of Toronto Toronto Health Economics and Technology Assessment Collaborative THETA and University of Toronto
    PLoS Curr 1:RRN1137. 2009
    ..Our analysis indicates this program will reduce influenza cases by 50%, preventing 35 deaths, and cutting treatment costs in half. A pandemic (H1N1) 2009 immunization program is likely to be highly cost-effective...
  46. pmc Estimation of the underlying burden of pertussis in adolescents and adults in southern ontario, Canada
    Ashleigh A McGirr
    Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    PLoS ONE 8:e83850. 2013
    ..Model projections strongly support enhancement of booster vaccination efforts in adults. ..
  47. ncbi request reprint Seasonality of infectious diseases
    David N Fisman
    Child Health Evaluative Sciences, Research Institute of the Hospital for Sick Children, and Ontario Provincial Public Health Laboratory, Toronto, Ontario, M5G 1E2, Canada
    Annu Rev Public Health 28:127-43. 2007
    ..Seasonality represents a rich area for future research...
  48. doi request reprint Projected cost-savings with herpes simplex virus screening in pregnancy: towards a new screening paradigm
    Ashleigh R Tuite
    Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario, Canada
    Sex Transm Infect 87:141-8. 2011
    ..The objective of this study was to assess the effectiveness and cost effectiveness of identifying pregnant women at risk of de novo HSV acquisition as a means of preventing vertical HSV transmission...
  49. pmc Seasonal Influenza Vaccine Allocation in the Canadian Population during a Pandemic
    Ashleigh Tuite
    Dalla Lana School of Public Health, University of Toronto Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada and Public Health Agency of Canada
    PLoS Curr 1:RRN1143. 2009
    ....
  50. doi request reprint Highly conserved cross-reactive CD4+ T-cell HA-epitopes of seasonal and the 2009 pandemic influenza viruses
    Venkata R S K Duvvuri
    MITACS Centre for Disease Modeling, York Institute of Health Research, Toronto, Ontario, Canada
    Influenza Other Respir Viruses 4:249-58. 2010
    ....
  51. pmc The cost-effectiveness of directly observed highly-active antiretroviral therapy in the third trimester in HIV-infected pregnant women
    Caitlin J McCabe
    Child Health Evaluative Sciences, Research Institute of the Hospital for Sick Children, Toronto, Ontario, Canada
    PLoS ONE 5:e10154. 2010
    ..Our objective was to project the effectiveness and cost-effectiveness of directly observed administration of antiretroviral drugs in pregnancy...