E N Fish

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi The role of circulating fibrocytes in inflammation and autoimmunity
    Carole L Galligan
    University Health Network, 67 College St, Toronto, Ontario, Canada
    J Leukoc Biol 93:45-50. 2013
  2. ncbi The X-files in immunity: sex-based differences predispose immune responses
    Eleanor N Fish
    Toronto General Research Institute, University Health Network, Department of Immunology, University of Toronto, Women s College Research Institute, Ontario, Canada
    Nat Rev Immunol 8:737-44. 2008
  3. ncbi Interferon-alpha/beta-receptor interactions: a complex story unfolding
    Raj Deonarain
    Toronto General Research Institute, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Curr Pharm Des 8:2131-7. 2002
  4. ncbi Interferon-beta is a key regulator of proinflammatory events in experimental autoimmune encephalomyelitis
    C L Galligan
    Toronto General Research Institute, University Health Network, Toronto, Canada
    Mult Scler 16:1458-73. 2010
  5. ncbi Review: IFN-alpha/beta receptor interactions to biologic outcomes: understanding the circuitry
    Melissa M Brierley
    Department of Immunology, University of Toronto, and Toronto General Research Institute, University Health Network, Toronto, Canada
    J Interferon Cytokine Res 22:835-45. 2002
  6. ncbi Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study
    Mona R Loutfy
    North York General Hospital, Toronto General Research Institute, Toronto, Ontario
    JAMA 290:3222-8. 2003
  7. ncbi Identification of a novel antigen-presenting cell population modulating antiinfluenza type 2 immunity
    Jae Kwang Yoo
    Toronto General Research Institute, University Health Network, Toronto, Ontario M5G 2M1, Canada
    J Exp Med 207:1435-51. 2010
  8. ncbi Fibrocyte activation in rheumatoid arthritis
    Carole L Galligan
    Toronto General Research Institute, University Health Network, 67 College Street, 4 424, Toronto, Ontario M5G 2M1, Canada
    Rheumatology (Oxford) 49:640-51. 2010
  9. ncbi Antiviral strategies: the present and beyond
    J D Burke
    Division of Cellular and Molecular Biology, Toronto General Research Institute, University Health Network, Toronto, Canada
    Curr Mol Pharmacol 2:32-9. 2009

Collaborators

  • Raj Deonarain
  • Carole L Galligan
  • C L Galligan
  • Jae Kwang Yoo
  • J D Burke
  • Mona R Loutfy
  • Melissa M Brierley
  • R Rahbar
  • E Baig
  • Vivian Bykerk
  • Carl Virtanen
  • L M Pennell
  • Katherine A Siminovitch
  • B Majchrzak-Kita
  • Omar D Perez
  • T T Murooka
  • Edward C Keystone
  • Patti Ferguson
  • Enoch K Y Lai
  • Gary Levy
  • Sarah Ward
  • Bryan Wolff
  • Gabriella A Farcas
  • Katharine A Siminovitch
  • Dieu H Pham
  • Hassan Deif
  • Mary Latchford
  • Kevin C Kain
  • Lawrence M Blatt
  • Hyoung Lho
  • James W Dennis
  • Elizabeth A LaMere
  • Margaret Chang

Detail Information

Publications9

  1. ncbi The role of circulating fibrocytes in inflammation and autoimmunity
    Carole L Galligan
    University Health Network, 67 College St, Toronto, Ontario, Canada
    J Leukoc Biol 93:45-50. 2013
    ..Increased numbers of circulating fibrocytes are observed in RA, systemic scleroderma, and Graves' disease. Here, we review the current literature and potential involvement of fibrocytes in inflammation and autoimmunity...
  2. ncbi The X-files in immunity: sex-based differences predispose immune responses
    Eleanor N Fish
    Toronto General Research Institute, University Health Network, Department of Immunology, University of Toronto, Women s College Research Institute, Ontario, Canada
    Nat Rev Immunol 8:737-44. 2008
    ..It is crucial to address sex-based differences in disease pathogenesis and in the pharmacokinetics and pharmacodynamics of therapeutic medications to provide optimal disease management for both sexes...
  3. ncbi Interferon-alpha/beta-receptor interactions: a complex story unfolding
    Raj Deonarain
    Toronto General Research Institute, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Curr Pharm Des 8:2131-7. 2002
    ..This review focuses on IFN-receptor interactions, the key residues involved in this interaction and the potential for targeted modifications of the ligand to enhance bioactivity...
  4. ncbi Interferon-beta is a key regulator of proinflammatory events in experimental autoimmune encephalomyelitis
    C L Galligan
    Toronto General Research Institute, University Health Network, Toronto, Canada
    Mult Scler 16:1458-73. 2010
    ..Interferon (IFN)-β is an effective therapy for relapsing-remitting multiple sclerosis, yet its mechanism of action remains ill-defined...
  5. ncbi Review: IFN-alpha/beta receptor interactions to biologic outcomes: understanding the circuitry
    Melissa M Brierley
    Department of Immunology, University of Toronto, and Toronto General Research Institute, University Health Network, Toronto, Canada
    J Interferon Cytokine Res 22:835-45. 2002
    ..Although many of the literature findings are specific to defined cell systems or are tissue restricted, the intent of this review is to place these signaling cascades and their effectors in the context of distinct biologic outcomes...
  6. ncbi Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study
    Mona R Loutfy
    North York General Hospital, Toronto General Research Institute, Toronto, Ontario
    JAMA 290:3222-8. 2003
    ..These findings suggest that further investigation may be warranted to determine the role of interferon alfacon-1 as a therapeutic agent for the treatment of SARS...
  7. ncbi Identification of a novel antigen-presenting cell population modulating antiinfluenza type 2 immunity
    Jae Kwang Yoo
    Toronto General Research Institute, University Health Network, Toronto, Ontario M5G 2M1, Canada
    J Exp Med 207:1435-51. 2010
    ..Collectively, our results identify and highlight the importance of LAPCs as immunomodulators of T2 immunity during influenza A virus infection...
  8. ncbi Fibrocyte activation in rheumatoid arthritis
    Carole L Galligan
    Toronto General Research Institute, University Health Network, 67 College Street, 4 424, Toronto, Ontario M5G 2M1, Canada
    Rheumatology (Oxford) 49:640-51. 2010
    ..Fibrocytes are multipotent circulating stem cells that may have a role in RA pathogenesis, perhaps as the precursors of the FLS cells, or by regulating FLS cell function...
  9. ncbi Antiviral strategies: the present and beyond
    J D Burke
    Division of Cellular and Molecular Biology, Toronto General Research Institute, University Health Network, Toronto, Canada
    Curr Mol Pharmacol 2:32-9. 2009
    ..Attention is focused on the potential use of interferons (IFN)-alpha/beta as broad spectrum antivirals in acute infections, to invoke both direct antiviral effects against viruses and activation of specific immune effector cells...