A Feinstein

..Our hypothesis was that difficulty sustaining attention in patients with MS would paradoxically be associated with less inattentional blindness...

..These findings provide preliminary data on the deleterious effects of drug-related violence on the Mexican media, amplifying the concerns expressed by journalist watchdog organizations monitoring the state of the press in the country...

..This paper presents a descriptive study, undertaken in 1993, of a Psychiatric Intensive Care Unit (PICU) serving a deprived inner-city area, investigating the role of ethnicity as a risk factor for admission to the unit...

..To assess the association between major depression and structural brain abnormalities in patients with multiple sclerosis (MS)...

..This study provides the first empirical data showing that a significant minority of contractors working in war zones are psychologically distressed and not receiving therapy...

..To examine neurologic and psychiatric correlates of suicidal intent in a community sample of 140 patients with MS...

..War journalists often confront situations of extreme danger in their work. Despite this, information on their psychological well-being is lacking...

..The threefold decline in prevalence rates for major depression over the course of a year demonstrates a good response to anti-depressant medication and possible beneficial effects of interferon beta-1b on mood...

..To assess psychiatric outcome in patients with an established diagnosis of a hyperkinetic (i.e. tremor, dystonia, myoclonus) psychogenic movement disorder...

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..Possible mechanisms that could account for this finding are discussed...

..e., irritability, sadness and tearfulness and how these symptoms of emotional dyscontrol may affect a subject's overall degree of psychological distress...

..Cognitive impairment is a common, disabling symptom of MS. We investigated the impact of cerebral perfusion and brain and lesion volumetry on cognitive performance in 45 patients with SPMS by using MR imaging...

..The purpose of this study was to determine whether the epsilon4 allele of APOE is associated with cognitive deficits in patients with MS...

..Thus, despite early neurosurgical differences, the results suggest that initial GCS scores do not clearly translate into neuropsychiatric sequelae at follow-up within the rubric of GCS 13-15...

..To assess prevalence rates and clinical correlates of anxiety disorders in patients with multiple sclerosis (MS)...

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..There will be acute harbingers of poor outcome following mild traumatic brain injury (TBI) in the elderly...

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..87). The pipeline yields a comprehensive and reliable individualized volumetric profile for subcortical vasculopathy that includes regionalized (26 brain regions) measures for: GM, WM, sCSF, vCSF, lacunar and non-lacunar pvSH and dwSH...

..We sought to quantify differences in MR imaging-based bookend-derived cerebral perfusion between cognitively impaired and nonimpaired patients with SPMS...

..A significant minority of patients with multiple sclerosis (MS) use cannabis, yet no study has examined the possible effects on mentation. Here, we report the emotional and cognitive correlates of street cannabis use in patients with MS...

..The aim of this review is to summarize the current literature on the neuropsychiatry of multiple sclerosis (MS)...

..To assess the utility of the Mini-Mental Status Examination (MMSE) among the older TBI population...

..Thus, all health professionals involved in the care of multiple sclerosis patients should have a good working knowledge of the neurotherapeutics of multiple sclerosis-related behavioral disorders...

..Clues to problem drinking in MS patients are the presence of a positive family history of mental illness and prominent anxiety...

..The clinical significance of this may become more evident with time in this vulnerable population...

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..4%), compared to those without, were found to have significantly lower scores on measures of working memory, processing speed, verbal memory and executive function. Potential mechanisms and implications for treatment are discussed...

..Traumatic brain injury was not associated with higher rates of amnestic mild cognitive impairment or dementia, and APOE-epsilon4 was not associated with cognition...

..Total CHIPS score and total hyperintense lesion load were correlated (sigma = 0.82, P < .0001). CONCLUSION: CHIPS is helpful in clinically predicting cognitive impairment in MS...

..There is no evidence from the recent war in Iraq suggesting that embedded journalists are at increased risk for psychological problems...

..The importance of future research addressing this imbalance is emphasized, for neuropsychiatric sequelae add significantly to the morbidity associated with MS...

..In mild to moderate TBI, subjective cognitive deficits are linked in large measure to comorbid major depression. However, other mechanisms may also account for these deficits...

..Major depression is common following traumatic brain injury (TBI), yet no studies to date have explored its relationship to psychosocial outcome in older adults with TBI...

..The purpose of this study was to examine the role of the serotonin transporter gene polymorphisms on the risk of major depression following traumatic brain injury (TBI)...

..Simultaneous quantification of atrophy and anatomically distinct hyperintensities is important for understanding cognitive impairments in dementia...

..The lesion data support a widely-dispersed neural network involving frontal, parietal, and brainstem regions in the pathophysiology of PBA...

..CONCLUSIONS: Major depression is associated with poor outcome across multiple domains. This study highlights the need for the early diagnosis and prompt treatment of major depression following mild traumatic brain injury...

..RESULTS: Older patients (age 60-plus) had lower rates of major depression than younger patients. CONCLUSION: Older patients seem to be relatively resilient to major depression shortly after mild TBI...

..This article summarizes these mental state changes, their pathogenesis and treatment. Correct diagnosis and treatment can substantially improve the quality of life for MS patients...

..Clinicians need to be alert to the presence of dizziness as an adverse prognostic indicator after mild to moderate TBI...

..01). CONCLUSIONS: These findings suggest that routine treatment of all MTBI patients offers little benefit; rather, targeting individuals with preinjury psychiatric problems may prove a more rational and cost-effective approach...

..However, it is unclear whether depression may cause or exacerbate cognitive problems as data remain equivocal. The current review attempts to clarify the relationship between these behavioral disorders...

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..We found that use of epigenomic microarray profiling in a relatively small number (15-25) of phenotypically discordant twin pairs has sufficient power to detect 1.2 fold epigenetic changes...