Andrei Fagarasanu

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. doi request reprint Orchestrating organelle inheritance in Saccharomyces cerevisiae
    Andrei Fagarasanu
    Department of Cell Biology, University of Alberta, Medical Sciences Building 5 14, Edmonton, Alberta T6G 2H7, Canada
    Curr Opin Microbiol 10:528-38. 2007
  2. ncbi request reprint Maintaining peroxisome populations: a story of division and inheritance
    Andrei Fagarasanu
    Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada
    Annu Rev Cell Dev Biol 23:321-44. 2007
  3. pmc Myosin-driven peroxisome partitioning in S. cerevisiae
    Andrei Fagarasanu
    Department of Cell Biology and 2 Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G2H7, Canada
    J Cell Biol 186:541-54. 2009
  4. pmc Pex3 peroxisome biogenesis proteins function in peroxisome inheritance as class V myosin receptors
    Jinlan Chang
    Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    J Cell Biol 187:233-46. 2009
  5. ncbi request reprint The peroxisomal membrane protein Inp2p is the peroxisome-specific receptor for the myosin V motor Myo2p of Saccharomyces cerevisiae
    Andrei Fagarasanu
    Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    Dev Cell 10:587-600. 2006
  6. pmc The peroxin Pex34p functions with the Pex11 family of peroxisomal divisional proteins to regulate the peroxisome population in yeast
    Robert J Tower
    Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada Institute for Systems Biology, Seattle, WA 98103, USA
    Mol Biol Cell 22:1727-38. 2011
  7. pmc An ER-peroxisome tether exerts peroxisome population control in yeast
    Barbara Knoblach
    Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada
    EMBO J 32:2439-53. 2013
  8. doi request reprint The peroxisomal protein importomer: a bunch of transients with expanding waistlines
    Fred D Mast
    Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    Nat Cell Biol 12:203-5. 2010
  9. ncbi request reprint Sharing the wealth: peroxisome inheritance in budding yeast
    Monica Fagarasanu
    Department of Cell Biology, University of Alberta, Medical Sciences Building 5 14, Edmonton, Alberta, Canada T6G 2H7
    Biochim Biophys Acta 1763:1669-77. 2006
  10. ncbi request reprint Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae
    Yuen Yi C Tam
    Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    J Biol Chem 280:34933-9. 2005

Collaborators

  • Richard A Rachubinski
  • Lois S Weisman
  • J N Mark Glover
  • Joel B Dacks
  • Michael R Logan
  • Fred D Mast
  • Monica Fagarasanu
  • Jinlan Chang
  • Barbara Knoblach
  • Yuen Yi C Tam
  • John D Aitchison
  • Robert J Tower
  • Marcello Marelli
  • Xuejun Sun
  • Nicolas Coquelle
  • Richard L Poirier
  • Dorian A Rachubinski
  • Gary A Eitzen
  • Alexey I Nesvizhskii
  • Jennifer J Smith
  • Ramsey A Saleem
  • Sunhee Jung
  • Eugene Yi
  • Ruedi Aebersold
  • David R Goodlett
  • Rowan H Christmas

Detail Information

Publications15

  1. doi request reprint Orchestrating organelle inheritance in Saccharomyces cerevisiae
    Andrei Fagarasanu
    Department of Cell Biology, University of Alberta, Medical Sciences Building 5 14, Edmonton, Alberta T6G 2H7, Canada
    Curr Opin Microbiol 10:528-38. 2007
    ..While organelle inheritance requires specific proteins tailored for the inheritance of each type of organelle, it is becoming apparent that a set of fundamental rules underlies the inheritance of all organelles...
  2. ncbi request reprint Maintaining peroxisome populations: a story of division and inheritance
    Andrei Fagarasanu
    Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada
    Annu Rev Cell Dev Biol 23:321-44. 2007
    ..The functions of Inp1p and Inp2p are cell cycle regulated and coordinated to ensure a fair distribution of peroxisomes at cytokinesis...
  3. pmc Myosin-driven peroxisome partitioning in S. cerevisiae
    Andrei Fagarasanu
    Department of Cell Biology and 2 Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G2H7, Canada
    J Cell Biol 186:541-54. 2009
    ....
  4. pmc Pex3 peroxisome biogenesis proteins function in peroxisome inheritance as class V myosin receptors
    Jinlan Chang
    Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    J Cell Biol 187:233-46. 2009
    ..Our results point to a temporal link between peroxisome formation and inheritance and delineate a general mechanism of peroxisome inheritance in eukaryotic cells...
  5. ncbi request reprint The peroxisomal membrane protein Inp2p is the peroxisome-specific receptor for the myosin V motor Myo2p of Saccharomyces cerevisiae
    Andrei Fagarasanu
    Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    Dev Cell 10:587-600. 2006
    ..To our knowledge, Inp2p is the first peroxisomal protein implicated in the vectorial movement of peroxisomes...
  6. pmc The peroxin Pex34p functions with the Pex11 family of peroxisomal divisional proteins to regulate the peroxisome population in yeast
    Robert J Tower
    Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada Institute for Systems Biology, Seattle, WA 98103, USA
    Mol Biol Cell 22:1727-38. 2011
    ....
  7. pmc An ER-peroxisome tether exerts peroxisome population control in yeast
    Barbara Knoblach
    Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada
    EMBO J 32:2439-53. 2013
    ..Peroxisomes are thus stably maintained over generations of cells through their continued interaction with tethers. ..
  8. doi request reprint The peroxisomal protein importomer: a bunch of transients with expanding waistlines
    Fred D Mast
    Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    Nat Cell Biol 12:203-5. 2010
    ..They achieve these feats of protein passage using a distinctive translocon whose highly dynamic aqueous pore can expand to accommodate the increasing girths of different peroxisome receptor-cargo complexes...
  9. ncbi request reprint Sharing the wealth: peroxisome inheritance in budding yeast
    Monica Fagarasanu
    Department of Cell Biology, University of Alberta, Medical Sciences Building 5 14, Edmonton, Alberta, Canada T6G 2H7
    Biochim Biophys Acta 1763:1669-77. 2006
    ..Tight coordination between Inp1p and Inp2p ensures a fair and harmonious spatial segregation of peroxisomes upon cell division...
  10. ncbi request reprint Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae
    Yuen Yi C Tam
    Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    J Biol Chem 280:34933-9. 2005
    ..Our findings support a direct role for the endoplasmic reticulum in de novo peroxisome formation...
  11. doi request reprint Molecular mechanisms of organelle inheritance: lessons from peroxisomes in yeast
    Andrei Fagarasanu
    Department of Cell Biology, University of Alberta, Edmonton, Alberta, T6G 2H7, Canada
    Nat Rev Mol Cell Biol 11:644-54. 2010
    ....
  12. pmc Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae
    Monica Fagarasanu
    Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    J Cell Biol 169:765-75. 2005
    ..Our findings are consistent with Inp1p acting as a factor that retains peroxisomes in cells and controls peroxisome division. Inp1p is the first peroxisomal protein directly implicated in peroxisome inheritance...
  13. doi request reprint Peroxisome biogenesis: something old, something new, something borrowed
    Fred D Mast
    Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada
    Physiology (Bethesda) 25:347-56. 2010
    ....
  14. pmc Peroxisomal peripheral membrane protein YlInp1p is required for peroxisome inheritance and influences the dimorphic transition in the yeast Yarrowia lipolytica
    Jinlan Chang
    Department of Cell Biology, University of Alberta, MSB 5 14, Edmonton, Alberta T6G 2H7, Canada
    Eukaryot Cell 6:1528-37. 2007
    ..This study reports the first analysis of organelle inheritance in a true dimorphic yeast and identifies the first protein required for peroxisome inheritance in Y. lipolytica...
  15. pmc Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane
    Marcello Marelli
    Institute for Systems Biology, Seattle, WA 98103, USA
    J Cell Biol 167:1099-112. 2004
    ..Rho1p regulates the assembly state of actin on the peroxisome membrane, thereby controlling peroxisome membrane dynamics and biogenesis...