Research Topics
| Andrei FagarasanuSummaryAffiliation: University of Alberta Country: Canada Publications
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Detail Information
Publications
Orchestrating organelle inheritance in Saccharomyces cerevisiaeAndrei Fagarasanu
Department of Cell Biology, University of Alberta, Medical Sciences Building 5 14, Edmonton, Alberta T6G 2H7, Canada
Curr Opin Microbiol 10:528-38. 2007..While organelle inheritance requires specific proteins tailored for the inheritance of each type of organelle, it is becoming apparent that a set of fundamental rules underlies the inheritance of all organelles...
Maintaining peroxisome populations: a story of division and inheritanceAndrei Fagarasanu
Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada
Annu Rev Cell Dev Biol 23:321-44. 2007..The functions of Inp1p and Inp2p are cell cycle regulated and coordinated to ensure a fair distribution of peroxisomes at cytokinesis...
Myosin-driven peroxisome partitioning in S. cerevisiaeAndrei Fagarasanu
Department of Cell Biology and 2 Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G2H7, Canada
J Cell Biol 186:541-54. 2009....
Pex3 peroxisome biogenesis proteins function in peroxisome inheritance as class V myosin receptorsJinlan Chang
Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
J Cell Biol 187:233-46. 2009..Our results point to a temporal link between peroxisome formation and inheritance and delineate a general mechanism of peroxisome inheritance in eukaryotic cells...
The peroxisomal membrane protein Inp2p is the peroxisome-specific receptor for the myosin V motor Myo2p of Saccharomyces cerevisiaeAndrei Fagarasanu
Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
Dev Cell 10:587-600. 2006..To our knowledge, Inp2p is the first peroxisomal protein implicated in the vectorial movement of peroxisomes...
The peroxin Pex34p functions with the Pex11 family of peroxisomal divisional proteins to regulate the peroxisome population in yeastRobert J Tower
Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada Institute for Systems Biology, Seattle, WA 98103, USA
Mol Biol Cell 22:1727-38. 2011....
The peroxisomal protein importomer: a bunch of transients with expanding waistlinesFred D Mast
Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
Nat Cell Biol 12:203-5. 2010..They achieve these feats of protein passage using a distinctive translocon whose highly dynamic aqueous pore can expand to accommodate the increasing girths of different peroxisome receptor-cargo complexes...
Sharing the wealth: peroxisome inheritance in budding yeastMonica Fagarasanu
Department of Cell Biology, University of Alberta, Medical Sciences Building 5-14, Edmonton, Alberta, Canada T6G 2H7
Biochim Biophys Acta 1763:1669-77. 2006..Tight coordination between Inp1p and Inp2p ensures a fair and harmonious spatial segregation of peroxisomes upon cell division...
Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiaeYuen Yi C Tam
Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
J Biol Chem 280:34933-9. 2005..Our findings support a direct role for the endoplasmic reticulum in de novo peroxisome formation...
Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiaeMonica Fagarasanu
Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
J Cell Biol 169:765-75. 2005..Our findings are consistent with Inp1p acting as a factor that retains peroxisomes in cells and controls peroxisome division. Inp1p is the first peroxisomal protein directly implicated in peroxisome inheritance...
Molecular mechanisms of organelle inheritance: lessons from peroxisomes in yeastAndrei Fagarasanu
Department of Cell Biology, University of Alberta, Edmonton, Alberta, T6G 2H7, Canada
Nat Rev Mol Cell Biol 11:644-54. 2010....
Peroxisome biogenesis: something old, something new, something borrowedFred D Mast
Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada
Physiology (Bethesda) 25:347-56. 2010....
Peroxisomal peripheral membrane protein YlInp1p is required for peroxisome inheritance and influences the dimorphic transition in the yeast Yarrowia lipolyticaJinlan Chang
Department of Cell Biology, University of Alberta, MSB 5 14, Edmonton, Alberta T6G 2H7, Canada
Eukaryot Cell 6:1528-37. 2007..This study reports the first analysis of organelle inheritance in a true dimorphic yeast and identifies the first protein required for peroxisome inheritance in Y. lipolytica...
Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membraneMarcello Marelli
Institute for Systems Biology, Seattle, WA 98103, USA
J Cell Biol 167:1099-112. 2004..Rho1p regulates the assembly state of actin on the peroxisome membrane, thereby controlling peroxisome membrane dynamics and biogenesis...
