Justin A Ezekowitz

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. ncbi The interaction among sex, hemoglobin and outcomes in a specialty heart failure clinic
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta T6G 2H7
    Can J Cardiol 21:165-71. 2005
  2. ncbi Novel pharmacologic therapies in development for acute decompensated heart failure
    Justin A Ezekowitz
    Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada
    Curr Cardiol Rep 15:329. 2013
  3. ncbi Standardizing care for acute decompensated heart failure in a large megatrial: the approach for the Acute Studies of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure (ASCEND-HF)
    Justin A Ezekowitz
    University of Alberta, Edmonton, Canada
    Am Heart J 157:219-28. 2009
  4. ncbi Declining in-hospital mortality and increasing heart failure incidence in elderly patients with first myocardial infarction
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
    J Am Coll Cardiol 53:13-20. 2009
  5. ncbi Aldosterone blockade and left ventricular dysfunction: a systematic review of randomized clinical trials
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
    Eur Heart J 30:469-77. 2009
  6. ncbi Comparison of one-year outcome (death and rehospitalization) in hospitalized heart failure patients with left ventricular ejection fraction >50% versus those with ejection fraction <50%
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Alberta, Edmonton, Canada
    Am J Cardiol 102:79-83. 2008
  7. ncbi Acute heart failure in the emergency department: short and long-term outcomes of elderly patients with heart failure
    Justin A Ezekowitz
    Division of Cardiology, Department of Medicine University of Alberta, Canada
    Eur J Heart Fail 10:308-14. 2008
  8. ncbi Trends in heart failure care: has the incident diagnosis of heart failure shifted from the hospital to the emergency department and outpatient clinics?
    Justin A Ezekowitz
    Division of Cardiology 2C2 WMC, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Eur J Heart Fail 13:142-7. 2011
  9. ncbi Insights into the change in brain natriuretic peptide after ST-elevation myocardial infarction (STEMI): why should it be better than baseline?
    Justin A Ezekowitz
    2C2 Cardiology UAH, University of Alberta, 8440 112 Street, Edmonton, AB T6G 2B7, Canada
    Can J Physiol Pharmacol 85:173-8. 2007
  10. ncbi The epidemiology and management of elderly patients with myocardial infarction or heart failure
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, 2C2 WMC, 8440 112 Street, Edmonton, Alberta T6G 2B7, Canada
    Heart Fail Rev 15:407-13. 2010

Detail Information

Publications49

  1. ncbi The interaction among sex, hemoglobin and outcomes in a specialty heart failure clinic
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta T6G 2H7
    Can J Cardiol 21:165-71. 2005
    ..Accordingly, the relationship among sex, anemia and outcomes in CHF was analyzed...
  2. ncbi Novel pharmacologic therapies in development for acute decompensated heart failure
    Justin A Ezekowitz
    Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada
    Curr Cardiol Rep 15:329. 2013
    ..This review will explore current and future novel pharmacologic therapies for the treatment of acute heart failure...
  3. ncbi Standardizing care for acute decompensated heart failure in a large megatrial: the approach for the Acute Studies of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure (ASCEND-HF)
    Justin A Ezekowitz
    University of Alberta, Edmonton, Canada
    Am Heart J 157:219-28. 2009
    ..This review provides key practical information regarding the current standard of care for patients with ADHF including the goals of therapy, management of acute and chronic medications, and discharge/transition of care planning...
  4. ncbi Declining in-hospital mortality and increasing heart failure incidence in elderly patients with first myocardial infarction
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
    J Am Coll Cardiol 53:13-20. 2009
    ..The purpose of this study was to examine the long-term incidence of heart failure (HF) in elderly patients with myocardial infarction (MI)...
  5. ncbi Aldosterone blockade and left ventricular dysfunction: a systematic review of randomized clinical trials
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
    Eur Heart J 30:469-77. 2009
    ..Aldosterone blockade has been used to treat acute myocardial infarction (MI) and chronic heart failure...
  6. ncbi Comparison of one-year outcome (death and rehospitalization) in hospitalized heart failure patients with left ventricular ejection fraction >50% versus those with ejection fraction <50%
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Alberta, Edmonton, Canada
    Am J Cardiol 102:79-83. 2008
    ....
  7. ncbi Acute heart failure in the emergency department: short and long-term outcomes of elderly patients with heart failure
    Justin A Ezekowitz
    Division of Cardiology, Department of Medicine University of Alberta, Canada
    Eur J Heart Fail 10:308-14. 2008
    ..We examined discharge rates, and whether outcomes, including mortality, differed based on admission status in AHF...
  8. ncbi Trends in heart failure care: has the incident diagnosis of heart failure shifted from the hospital to the emergency department and outpatient clinics?
    Justin A Ezekowitz
    Division of Cardiology 2C2 WMC, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Eur J Heart Fail 13:142-7. 2011
    ..Our objective was to describe the incidence, prevalence, or outcomes for HF patients diagnosed in the outpatient or emergency department (ED) setting...
  9. ncbi Insights into the change in brain natriuretic peptide after ST-elevation myocardial infarction (STEMI): why should it be better than baseline?
    Justin A Ezekowitz
    2C2 Cardiology UAH, University of Alberta, 8440 112 Street, Edmonton, AB T6G 2B7, Canada
    Can J Physiol Pharmacol 85:173-8. 2007
    ..This likely reflects the variability in NT-proBNP at presentation and the ability to integrate subsequent important physiologic sequelae of STEMI such as reperfusion and infarct size...
  10. ncbi The epidemiology and management of elderly patients with myocardial infarction or heart failure
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, 2C2 WMC, 8440 112 Street, Edmonton, Alberta T6G 2B7, Canada
    Heart Fail Rev 15:407-13. 2010
    ..Attention to this issue is important when selecting treatment strategies and a focus on the goals of care is critical when decisions for care must be undertaken...
  11. ncbi The correlation of standard heart failure assessment and palliative care questionnaires in a multidisciplinary heart failure clinic
    Justin A Ezekowitz
    Division of Cardiology and Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta
    J Pain Symptom Manage 42:379-87. 2011
    ....
  12. ncbi Predicting chronic left ventricular dysfunction 90 days after ST-segment elevation myocardial infarction: An Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) Substudy
    Justin A Ezekowitz
    University of Alberta and the Canadian VIGOUR Center, Edmonton, Alberta, Canada
    Am Heart J 160:272-8. 2010
    ....
  13. ncbi Association between direct measures of body composition and prognostic factors in chronic heart failure
    Antigone Oreopoulos
    School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Mayo Clin Proc 85:609-17. 2010
    ....
  14. ncbi Incidence of heart failure and mortality after acute coronary syndromes
    Padma Kaul
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Am Heart J 165:379-85.e2. 2013
    ..We examined the 1-year incidence of HF and its association with mortality among patients surviving their first acute coronary syndrome (ACS) hospitalization...
  15. ncbi Do anthropometric indices accurately reflect directly measured body composition in men and women with chronic heart failure?
    Antigone Oreopoulos
    School of Public Health, University of Alberta, 8440 112th Street, Edmonton, AB, Canada
    Congest Heart Fail 17:90-2. 2011
    ..Anthropometric indices do not accurately reflect body composition in patients with CHF, especially in women. When accurate assessment of body composition is required, direct measurements should be obtained...
  16. ncbi Acute heart failure: perspectives from a randomized trial and a simultaneous registry
    Justin A Ezekowitz
    Mazankowski Alberta Heart Institute and the University of Alberta, Edmonton, AB, Canada
    Circ Heart Fail 5:735-41. 2012
    ....
  17. ncbi Impact of specialist follow-up in outpatients with congestive heart failure
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alta
    CMAJ 172:189-94. 2005
    ..Methods to improve timely and appropriate access to specialists and to improve collaborative care structures are needed...
  18. ncbi Resource use in the last 6 months of life among patients with heart failure in Canada
    Padma Kaul
    Department of Medicine, Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
    Arch Intern Med 171:211-7. 2011
    ..Heart failure (HF) is a debilitating and chronic condition associated with significant morbidity and mortality. However, much less is known about end-of-life (EOL) costs among patients with HF...
  19. ncbi N-terminal pro-brain natriuretic peptide and the timing, extent and mortality in ST elevation myocardial infarction
    Justin A Ezekowitz
    University of Alberta, Edmonton, Canada
    Can J Cardiol 22:393-7. 2006
    ..NT-proBNP at baseline, 24 h and 72 h after presentation with acute STEMI, is an independent predictor of a poor outcome and adds clinically useful prognostic information...
  20. ncbi Anemia is common in heart failure and is associated with poor outcomes: insights from a cohort of 12 065 patients with new-onset heart failure
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
    Circulation 107:223-5. 2003
    ..Further research into the mechanisms of anemia in CHF and randomized controlled trials to test whether correction of anemia improves prognosis in CHF are needed...
  21. ncbi Risk stratification schemes, anticoagulation use and outcomes: the risk--treatment paradox in patients with newly diagnosed non-valvular atrial fibrillation
    Roopinder K Sandhu
    Department of Cardiology, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada
    Heart 97:2046-50. 2011
    ..To examine whether warfarin use and outcomes differ across CHADS(2) and CHA(2)DS(2)-VASc risk strata for non-valvular atrial fibrillation (NVAF)...
  22. ncbi Heart failure is a risk factor for orthopedic fracture: a population-based analysis of 16,294 patients
    Sean van Diepen
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
    Circulation 118:1946-52. 2008
    ..Heart failure (HF) is associated with factors that may contribute to accelerated bone loss and subsequent fractures. Whether it leads to an increased fracture risk is unknown...
  23. ncbi Mortality and readmission of patients with heart failure, atrial fibrillation, or coronary artery disease undergoing noncardiac surgery: an analysis of 38 047 patients
    Sean van Diepen
    Mazankowski Alberta Heart Institute, Division of Cardiology, Department of Medicine, University of Alberta, Edmonton, Canada
    Circulation 124:289-96. 2011
    ..The purpose of this study is to compare the postoperative mortality of patients with HF, AF, or CAD undergoing major and minor noncardiac surgery...
  24. ncbi Ethnic differences in 1-year mortality among patients hospitalised with heart failure
    Padma Kaul
    Division of Cardiology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Heart 97:1048-53. 2011
    ..The objective of this study was to examine the impact of ethnicity on 1-year mortality among patients with heart failure in a single payer healthcare system with universal access...
  25. ncbi Does silent myocardial infarction add prognostic value in ST-elevation myocardial infarction patients without a history of prior myocardial infarction? Insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) Trial
    Mustafa Toma
    University of Alberta, Edmonton, Alberta, Canada
    Am Heart J 160:671-7. 2010
    ..ST-elevation myocardial infarction (STEMI) patients with a prior MI history have worse outcomes. The prognostic significance of silent MI (pathologic Q waves outside the ST-elevation territory) in STEMI is unclear...
  26. ncbi Assessment of dyspnea in acute decompensated heart failure: insights from ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure) on the contributions of peak expiratory flow
    Justin A Ezekowitz
    University of Alberta, Edmonton, Canada
    J Am Coll Cardiol 59:1441-8. 2012
    ..This study hypothesized that peak expiratory flow rate (PEFR) would increase with acute heart failure (AHF) treatment over the first 24 h, related to a Dyspnea Index (DI) change and treatment effect...
  27. ncbi Patterns of care and outcomes differ for urban versus rural patients with newly diagnosed heart failure, even in a universal healthcare system
    John Michael Gamble
    Department of Public Health Sciences, University of Alberta, Edmonton, Canada
    Circ Heart Fail 4:317-23. 2011
    ..We aimed to determine whether outcomes differ for patients with incident heart failure (HF) by urban-rural status...
  28. ncbi Meta-analysis: cardiac resynchronization therapy for patients with less symptomatic heart failure
    Nawaf S Al-Majed
    Mazankowski Alberta Heart Institute, University of Alberta, Canada
    Ann Intern Med 154:401-12. 2011
    ..Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in patients with advanced symptoms of heart failure...
  29. ncbi Comparison of direct body composition assessment methods in patients with chronic heart failure
    Antigone Oreopoulos
    School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    J Card Fail 16:867-72. 2010
    ..We examined the validity of leg-to-leg bioelectrical impedance analysis (BIA) and near-infrared interactance (NIR) to assess body composition in chronic heart failure (CHF) patients...
  30. ncbi Systematic review: implantable cardioverter defibrillators for adults with left ventricular systolic dysfunction
    Justin A Ezekowitz
    University of Alberta Evidence Based Practice Center, Edmonton, Alberta, Canada
    Ann Intern Med 147:251-62. 2007
    ..Patients with left ventricular (LV) systolic dysfunction have an increased risk for ventricular arrhythmias...
  31. ncbi Heart failure is a clinically and densitometrically independent risk factor for osteoporotic fractures: population-based cohort study of 45,509 subjects
    Sumit R Majumdar
    Department of Medicine, University of Alberta, 2F1 24 Walter Mackenzie Health Sciences Centre, University of Alberta Hospital, 8440 112th Street, Edmonton, Alberta, Canada T6G 2B7
    J Clin Endocrinol Metab 97:1179-86. 2012
    ..The aim of the study was to determine whether heart failure is associated with an increased risk of major osteoporotic fractures that is independent of bone mineral density (BMD)...
  32. ncbi Use of oral proton pump inhibitors is not associated with harm in patients with chronic heart failure in an ambulatory setting
    Gavin Y Oudit
    Division of Cardiology, Department of Medicine, Mazankowski Alberta Heart Institute, University of Alberta, 8440 112 Street, Edmonton, Alberta, Canada
    Eur J Heart Fail 13:1211-5. 2011
    ..We conducted this study to determine whether PPI use was associated with excess mortality in patients with both ischaemic and non-ischaemic heart failure (HF)...
  33. ncbi Systematic review: cardiac resynchronization in patients with symptomatic heart failure
    Finlay A McAlister
    The University of Alberta and Capital Health Evidence based Practice Center, Edmonton, Alberta, Canada
    Ann Intern Med 141:381-90. 2004
    ..Even with optimal pharmacotherapy, symptomatic heart failure is associated with substantial morbidity and mortality...
  34. ncbi Meta-analysis: beta-blocker dose, heart rate reduction, and death in patients with heart failure
    Finlay A McAlister
    University of Alberta Hospital, 2F1 21 Walter Mackenzie Health Sciences Centre, 8440 112 Street, Edmonton, Alberta, Canada
    Ann Intern Med 150:784-94. 2009
    ..Guidelines recommend that patients with heart failure receive beta-blockers in doses used in the trials that have proven their efficacy. Although the adverse effects of beta-blockade are dose-related, it is unclear whether the benefits are...
  35. ncbi The unrecognized burden of osteoporosis-related vertebral fractures in patients with heart failure
    Kristin J Lyons
    Department of Medicine, University of Alberta, Edmonton, Canada
    Circ Heart Fail 4:419-24. 2011
    ..Our objectives were to describe the prevalence and predictors of the most common osteoporotic fracture, vertebral compression fractures (VCF), in patients with HF...
  36. ncbi The epidemiology of atrial fibrillation in adults depends on locale of diagnosis
    Roopinder K Sandhu
    Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada
    Am Heart J 161:986-992.e1. 2011
    ..Previous studies on atrial fibrillation (AF) epidemiology have used various case definitions for AF, but the effect of location of diagnosis on the apparent epidemiology of AF is unknown...
  37. ncbi The prevalence of natural health product use in patients with acute cardiovascular disease
    Aws Alherbish
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    PLoS ONE 6:e19623. 2011
    ....
  38. ncbi Association of global weather changes with acute coronary syndromes: gaining insights from clinical trials data
    Jeffrey A Bakal
    Faculty of Medicine and Dentistry, Canadian VIGOUR Centre, University of Alberta, Research Innovation, 2 132 Li Ka Shing Centre for Heath, Edmonton, Alberta, Canada, T6G 2E1
    Int J Biometeorol 57:401-8. 2013
    ..Additionally there appeared to be an association with gender, region and a history of stroke. This methodology may provide a useful global insight into assessing the biometeorologic component of diseases from international data...
  39. ncbi Neither diabetes nor glucose-lowering drugs are associated with mortality after noncardiac surgery in patients with coronary artery disease or heart failure
    Mikael Hanninen
    Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada
    Can J Cardiol 29:423-8. 2013
    ..It is unclear whether diabetes mellitus or use of particular glucose-lowering agents is associated with increased risk of mortality after noncardiac surgery in patients with known cardiac disease...
  40. ncbi The 2010 Canadian Cardiovascular Society guidelines for the diagnosis and management of heart failure update: Heart failure in ethnic minority populations, heart failure and pregnancy, disease management, and quality improvement/assurance programs
    Jonathan G Howlett
    University of Calgary, Alberta, Canada
    Can J Cardiol 26:185-202. 2010
    ..Both of these topics were written from a clinical perspective. It is hoped that the present update will become a useful tool for health care providers and planners in the ongoing evolution of care for HF patients in Canada...
  41. ncbi The timing of implantable cardioverter-defibrillator implantation in patients with heart failure
    Nawaf S Al-Majed
    Mazankowski Alberta Heart Institute, University of Alberta, 8440 112 Street, Edmonton, Alberta, Canada
    Curr Cardiol Rep 14:299-307. 2012
    ....
  42. ncbi Angiotensin receptor blockers and risk of myocardial infarction: systematic review
    Michael A McDonald
    Division of Cardiology, University of Alberta, 2C2 WMC, University of Alberta Hospital, 8440-112 Street, Edmonton, AB, Canada T6G 2B7
    BMJ 331:873. 2005
    ..Until further information specifically dealing with this issue is available from large prospective trials, our findings may alleviate recent concerns over the safety of this class of medications...
  43. ncbi Implantable cardioverter defibrillators in primary and secondary prevention: a systematic review of randomized, controlled trials
    Justin A Ezekowitz
    University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    Ann Intern Med 138:445-52. 2003
    ..However, their impact on total mortality is sensitive to baseline risk for arrhythmic death. Decisions about resource allocation for ICDs depend on accurate stratification of patients according to risk...
  44. ncbi The relationship between body mass index, treatment, and mortality in patients with established coronary artery disease: a report from APPROACH
    Antigone Oreopoulos
    Department of Clinical Epidemiology, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Eur Heart J 30:2584-92. 2009
    ..Patients with obesity may be presenting earlier and receiving more aggressive treatment compared with those with normal BMI...
  45. ncbi Carotid chemoreceptor modulation of blood flow during exercise in healthy humans
    Michael K Stickland
    Division of Pulmonary Medicine, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    J Physiol 589:6219-30. 2011
    ..These findings indicate that the carotid chemoreceptor contributes to skeletal muscle blood flow regulation during normoxic exercise in healthy humans, but that the influence of the CC on blood flow regulation in hypoxia is limited...
  46. ncbi Stroke: strategies for primary prevention
    Justin A Ezekowitz
    University of Alberta, Faculty of Medicine and Dentistry, Edmonton, Alberta
    Am Fam Physician 68:2379-86. 2003
    ..Controversy exists about the roles of angiotensin-converting enzyme inhibitors and aspirin in the primary prevention of stroke...
  47. ncbi Stretching for prediction: the case for brain natriuretic peptide
    Justin A Ezekowitz
    Can J Cardiol 20:684-5. 2004
  48. ncbi Anemia in patients with advanced heart failure
    Justin A Ezekowitz
    J Am Coll Cardiol 49:2301; author reply 2302. 2007
  49. ncbi Canadian Cardiovascular Society Consensus Conference guidelines on heart failure--2008 update: best practices for the transition of care of heart failure patients, and the recognition, investigation and treatment of cardiomyopathies
    J Malcom
    University of Western Ontario, London, Canada
    Can J Cardiol 24:21-40. 2008
    ....