Derek Exner

Summary

Affiliation: University of Calgary
Country: Canada

Publications

  1. doi request reprint Canadian Cardiovascular Society guidelines on the use of cardiac resynchronization therapy: evidence and patient selection
    Derek V Exner
    Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada
    Can J Cardiol 29:182-95. 2013
  2. pmc Noninvasive risk stratification after myocardial infarction: rationale, current evidence and the need for definitive trials
    Derek Exner
    Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Ablerta
    Can J Cardiol 25:21A-27A. 2009
  3. ncbi request reprint Role of risk stratification after myocardial infarction
    Vikas Kuriachan
    Derek V Exner, MD, MPH Libin Cardiovascular Institute of Alberta, University of Calgary, 3330 Hospital Drive NW, Room G208, Calgary, AB, Canada T2N 4N1
    Curr Treat Options Cardiovasc Med 11:10-21. 2009
  4. doi request reprint Implantable cardioverter defibrillator therapy for patients with less severe left ventricular dysfunction
    Derek V Exner
    Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada
    Curr Opin Cardiol 24:61-7. 2009
  5. doi request reprint Arguments prove nothing unless verified. A commentary on Kaufman's "Epidemiologic analysis of racial/ethnic disparities: some fundamental issues and a cautionary example"
    Derek V Exner
    Soc Sci Med 66:1675-7. 2008
  6. ncbi request reprint Conduction time oscillations precede the spontaneous termination of human atrioventricular reciprocating tachycardia
    D V Exner
    Department of Medicine, Division of Cardiology, University of Calgary, Canada
    J Interv Card Electrophysiol 4:231-9. 2000
  7. ncbi request reprint Is antitachycardia pacing a safe and efficacious alternative to shocks for fast ventricular tachyarrhythmia treatment?
    Derek V Exner
    Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada
    Nat Clin Pract Cardiovasc Med 2:68-9. 2005
  8. ncbi request reprint Emphasizing quality in qualitative research: devices to control arrhythmias
    Derek V Exner
    Canadian Institutes of Health Research
    J Cardiovasc Electrophysiol 16:391-3. 2005
  9. ncbi request reprint Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction
    D V Exner
    Cardiovascular Research Group, University of Calgary, Alta, Canada
    N Engl J Med 344:1351-7. 2001
  10. ncbi request reprint Electrical storm presages nonsudden death: the antiarrhythmics versus implantable defibrillators (AVID) trial
    D V Exner
    University of Calgary, Canada
    Circulation 103:2066-71. 2001

Detail Information

Publications35

  1. doi request reprint Canadian Cardiovascular Society guidelines on the use of cardiac resynchronization therapy: evidence and patient selection
    Derek V Exner
    Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada
    Can J Cardiol 29:182-95. 2013
    ..These guidelines were externally reviewed by experts, modified based on those reviews, and will be updated as new knowledge is acquired...
  2. pmc Noninvasive risk stratification after myocardial infarction: rationale, current evidence and the need for definitive trials
    Derek Exner
    Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Ablerta
    Can J Cardiol 25:21A-27A. 2009
    ..Until such data are available, significant LV dysfunction alone and in combination with the induction of VT/VF during invasive testing in the nonacute post-MI period remain the only proven methods to guide prophylactic ICD therapy...
  3. ncbi request reprint Role of risk stratification after myocardial infarction
    Vikas Kuriachan
    Derek V Exner, MD, MPH Libin Cardiovascular Institute of Alberta, University of Calgary, 3330 Hospital Drive NW, Room G208, Calgary, AB, Canada T2N 4N1
    Curr Treat Options Cardiovasc Med 11:10-21. 2009
    ..Until the data from these studies are available, severe LV dysfunction remains the only proven approach to guide implantable defibrillator therapy after MI...
  4. doi request reprint Implantable cardioverter defibrillator therapy for patients with less severe left ventricular dysfunction
    Derek V Exner
    Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada
    Curr Opin Cardiol 24:61-7. 2009
    ..Given the large pool of patients with less severe LV dysfunction and a modest risk of SCD, methods to identify those who might benefit from an ICD are required...
  5. doi request reprint Arguments prove nothing unless verified. A commentary on Kaufman's "Epidemiologic analysis of racial/ethnic disparities: some fundamental issues and a cautionary example"
    Derek V Exner
    Soc Sci Med 66:1675-7. 2008
  6. ncbi request reprint Conduction time oscillations precede the spontaneous termination of human atrioventricular reciprocating tachycardia
    D V Exner
    Department of Medicine, Division of Cardiology, University of Calgary, Canada
    J Interv Card Electrophysiol 4:231-9. 2000
    ..002. Conduction time oscillations, which are related to apparent enhancement in atrio-His or ventriculoatrial conduction, frequently precede the spontaneous termination of reentry in humans...
  7. ncbi request reprint Is antitachycardia pacing a safe and efficacious alternative to shocks for fast ventricular tachyarrhythmia treatment?
    Derek V Exner
    Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada
    Nat Clin Pract Cardiovasc Med 2:68-9. 2005
  8. ncbi request reprint Emphasizing quality in qualitative research: devices to control arrhythmias
    Derek V Exner
    Canadian Institutes of Health Research
    J Cardiovasc Electrophysiol 16:391-3. 2005
  9. ncbi request reprint Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction
    D V Exner
    Cardiovascular Research Group, University of Calgary, Alta, Canada
    N Engl J Med 344:1351-7. 2001
    ....
  10. ncbi request reprint Electrical storm presages nonsudden death: the antiarrhythmics versus implantable defibrillators (AVID) trial
    D V Exner
    University of Calgary, Canada
    Circulation 103:2066-71. 2001
    ..However, insufficient data exist regarding its prognostic significance...
  11. ncbi request reprint Paced QT dispersion and QT morphology after radiofrequency atrioventricular junction ablation: impact of left ventricular function
    Satish R Raj
    Division of Cardiology, Foothills Medical Center and the Cardiovascular Disease Research Group, University of Calgary, Calgary, Alberta, Canada
    Pacing Clin Electrophysiol 26:662-8. 2003
    ..02) function groups. Following AVJ ablation, QTdisp increased during a sudden rate drop in patients with reduced LV function, but not in patients with normal LV function...
  12. ncbi request reprint Randomized controlled trial of fixed rate versus rate responsive pacing after radiofrequency atrioventricular junction ablation: quality of life, ventricular refractoriness, and paced QT dispersion
    Henry J Duff
    Cardiovascular Disease Research Group, University of Calgary Health Sciences Centre, HSC 1632, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
    J Cardiovasc Electrophysiol 14:1163-70. 2003
    ..The aim of this study was to provide information about the balance between measures of quality of life versus measures of electrical remodeling achieved by pacing with different rate modalities in a randomized pilot clinical trial...
  13. doi request reprint Beneficial effects of statin therapy for prevention of atrial fibrillation following DDDR pacemaker implantation
    Anne M Gillis
    Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary and Calgary Health Region, Calgary, AB, Canada
    Eur Heart J 29:1873-80. 2008
    ..The clinical predictors of at/af recurrence following dual-chamber pacemaker insertion were examined in 185 consecutive patients with paroxysmal AF...
  14. ncbi request reprint Cigarette smoking, stages of change, and major depression in the Canadian population
    Salma M Khaled
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta
    Can J Psychiatry 54:204-8. 2009
    ..To describe the 12-month prevalence of major depression in relation to smoking status, nicotine dependence levels, commitment to quit, attempts to quit, and maintenance of smoking cessation in the Canadian general population...
  15. doi request reprint Impact of atrial antitachycardia pacing and atrial pace prevention therapies on atrial fibrillation burden over long-term follow-up
    Anne M Gillis
    Health Sciences Centre, Department of Cardiac Sciences, University of Calgary, Calgary Health Region, Rm 1634, 3330 Hospital Dr NW, Calgary, Alberta, Canada
    Europace 11:1041-7. 2009
    ..Accordingly, we compared atrial antitachycardia pacing (ATP) therapy and combined atrial ATP and atrial pace prevention (ATP + Prevention) algorithms to conventional DDD/R pacing for prevention of AT/AF over long-term follow-up...
  16. ncbi request reprint Noninvasive risk assessment early after a myocardial infarction the REFINE study
    Derek V Exner
    Libin Cardiovascular Institute of Alberta, Calgary, Canada Department of Community Health Sciences, University of Calgary, Calgary, Canada
    J Am Coll Cardiol 50:2275-84. 2007
    ....
  17. doi request reprint Meta-analysis of the effectiveness and safety of catheter ablation of atrial fibrillation in patients with versus without left ventricular systolic dysfunction
    Stephen B Wilton
    Libin Cardiovascular Institute of Alberta, University of Calgary, Canada
    Am J Cardiol 106:1284-91. 2010
    ..Significant improvements in left ventricular ejection fractions after ablation were observed in those with LVSD. Randomized trials are needed given the limitations of present data...
  18. ncbi request reprint Atrial flutter and the risk of thromboembolism: a systematic review and meta-analysis
    William A Ghali
    Department of Medicine, University of Calgary, Alberta, Canada
    Am J Med 118:101-7. 2005
    ..We conducted a systematic review and meta-analysis of observational studies to assess the risk of thromboembolism associated with atrial flutter...
  19. ncbi request reprint Quality of life and psychological impact of implantable cardioverter defibrillators: focus on randomized controlled trial data
    Michael John McCready
    Cardiovascular Research Group, University of Calgary, Calgary, Alberta, Canada
    Card Electrophysiol Rev 7:63-70. 2003
    ....
  20. ncbi request reprint Ventricular high-rate episodes in pacemaker diagnostics identify a high-risk subgroup of patients with tachy-brady syndrome
    Rik Willems
    Department of Cardiac Sciences and Department of Community Medicine, University of Calgary, Alberta, Canada
    Heart Rhythm 1:414-21. 2004
    ..The purpose of this study was to evaluate the frequency and clinical significance of ventricular high-rate (VHR) episodes (ventricular rate >162 bpm) in patients with symptomatic bradycardia and paroxysmal atrial fibrillation (AF)...
  21. doi request reprint Post-exercise assessment of cardiac repolarization alternans in patients with coronary artery disease using the modified moving average method
    Michael P Slawnych
    Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada
    J Am Coll Cardiol 53:1130-7. 2009
    ..We sought to evaluate the utility of T-wave alternans (TWA) assessment in the immediate post-exercise period to identify and validate cutpoints for the modified moving average (MMA) assessment method...
  22. doi request reprint Relationship between left ventricular lead position using a simple radiographic classification scheme and long-term outcome with resynchronization therapy
    Stephen B Wilton
    Libin Cardiovascular Institute of Alberta, University of Calgary, Canada
    J Interv Card Electrophysiol 23:219-27. 2008
    ..Benefit from cardiac resynchronization therapy (CRT) is likely influenced by the location of the left ventricular (LV) lead...
  23. ncbi request reprint Prophylactic amiodarone for prevention of atrial fibrillation after cardiac surgery: a meta-analysis
    Sean M Bagshaw
    Department of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia
    Ann Thorac Surg 82:1927-37. 2006
    ..The current evidence supports recommending the routine use of perioperative amiodarone for cardiac surgery...
  24. ncbi request reprint Do population studies confirm the benefit of oral anticoagulation in atrial fibrillation demonstrated in clinical trials?
    Rik Willems
    Cardiovascular Research Group, University of Calgary, Calgary, Canada
    J Interv Card Electrophysiol 10:9-16. 2004
    ..This paper gives an overview of the available evidence of the effectiveness of oral anticoagulation in population studies and tries to identify some remaining barriers in the prescription of oral anticoagulation in real life...
  25. doi request reprint Single diagnostic pacing maneuver for supraventricular tachycardia
    George D Veenhuyzen
    Libin Cardiovascular Institute of Alberta, University of Calgary and Calgary Health Region, Foothills Medical Centre, Calgary, Alberta, Canada
    Heart Rhythm 5:1152-8. 2008
    ..Therefore, diagnosis often requires the integration of multiple pieces of information and/or pacing maneuvers, which adds to the complexity of catheter ablation procedures...
  26. doi request reprint Polymorphisms in multiple genes are associated with resting heart rate in a stepwise allele-dependent manner
    Stephen B Wilton
    Libin Cardiovascular Institute, University of Calgary, Alberta, Canada
    Heart Rhythm 5:694-700. 2008
    ..The purpose of this study was to use a candidate gene approach to identify common polymorphisms that are associated with resting sinus heart rate in a population without overt cardiovascular disease...
  27. doi request reprint Predictive value of repeated versus single N-terminal pro B-type natriuretic peptide measurements early after-myocardial infarction
    Sabrina Sandhu
    Libin Cardiovascular Institute of Alberta, Calgary, Canada
    Pacing Clin Electrophysiol 32:S86-9. 2009
    ..We compared the predictive value of a modestly and persistently elevated, versus a single, markedly elevated measurement of N terminal pro-BNP (NT-BNP) early after MI...
  28. ncbi request reprint Quality of life in the antiarrhythmics versus implantable defibrillators trial: impact of therapy and influence of adverse symptoms and defibrillator shocks
    Eleanor B Schron
    Clinical Trials Group, National Heart, Lung, and Blood Institute, Bethesda, MD, USA
    Circulation 105:589-94. 2002
    ..However, the relative impact of these therapies on self-perceived quality of life (QoL) is unknown...
  29. ncbi request reprint Do we need a randomized trial of defibrillator therapy in every subset of patients with increased risk of sudden death?
    Derek V Exner
    J Cardiovasc Electrophysiol 14:574-7. 2003
  30. doi request reprint Outcome of the Fidelis implantable cardioverter-defibrillator lead advisory: a report from the Canadian Heart Rhythm Society Device Advisory Committee
    Andrew D Krahn
    London Health Sciences Center, University Campus, 339 Windermere Road, London, Ontario, Canada N6A 5A5
    Heart Rhythm 5:639-42. 2008
    ..The Medtronic Sprint Fidelis family of leads has recently been the subject of a widespread advisory. Lead failure rates are estimated at 2.3% at 30 months, 2.6 times the failure rate of the reference Medtronic 6947 lead...
  31. ncbi request reprint Quality of life in patients with life-threatening arrhythmias: does choice of therapy make a difference?
    Derek V Exner
    Am Heart J 144:208-11. 2002
  32. ncbi request reprint Partner quality of life in the antiarrhythmics versus implantable defibrillators trial
    Louise S Jenkins
    Institute for Educators in Nursing and Health Professions, University of Maryland School of Nursing, Baltimore, MD, USA
    J Cardiovasc Nurs 22:472-9. 2007
    ..This study describes the QOL of partners of patients with serious ventricular dysrhythmias enrolled in the Antiarrhythmics Versus Implantable Defibrillators trial...
  33. ncbi request reprint I can see clearly now...but at what cost?
    Anne M Gillis
    Heart Rhythm 3:879-80. 2006
  34. ncbi request reprint Long-term effectiveness of cardiac resynchronization therapy: Futile or useful?
    Derek V Exner
    Can J Cardiol 21:419-22. 2005
  35. pmc Mitral insufficiency and morbidity and mortality in left ventricular dysfunction
    Roger J F Baskett
    Maritime Heart Centre and the Division of Cardiac Surgery, Department of Surgery, Dalhousie University, Halifax, NS, Canada
    Can J Cardiol 23:797-800. 2007
    ..Mitral insufficiency is known to occur in a substantial proportion of patients with heart failure. Its relationship with morbidity and mortality is poorly described...