D H Evans

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. pmc Enzymatic processing of replication and recombination intermediates by the vaccinia virus DNA polymerase
    Michael D Hamilton
    Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, The University of Alberta Edmonton, AB, Canada T6G 2H7
    Nucleic Acids Res 33:2259-68. 2005
  2. pmc Duplex strand joining reactions catalyzed by vaccinia virus DNA polymerase
    Michael D Hamilton
    Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, The University of Alberta, Edmonton, AB, Canada T6G 2H7
    Nucleic Acids Res 35:143-51. 2007
  3. pmc Vaccinia virus-encoded ribonucleotide reductase subunits are differentially required for replication and pathogenesis
    Don B Gammon
    Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada
    PLoS Pathog 6:e1000984. 2010
  4. pmc Myxoma virus oncolytic efficiency can be enhanced through chemical or genetic disruption of the actin cytoskeleton
    Chad R Irwin
    Department of Medical Microbiology and Immunology, University of Alberta, Edmonton Alberta, Canada
    PLoS ONE 8:e84134. 2013
  5. pmc Genomic analysis of the vaccinia virus strain variants found in Dryvax vaccine
    Li Qin
    Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, 6020 Katz Group Centre, Edmonton, AB T6G 2H7, Canada
    J Virol 85:13049-60. 2011
  6. pmc Vaccinia virus particles mix inefficiently, and in a way that would restrict viral recombination, in coinfected cells
    Y C James Lin
    Alberta Institute for Viral Immunology and Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, The University of Alberta, Alberta, Canada
    J Virol 84:2432-43. 2010
  7. pmc Inhibition of HIV-1 by octadecyloxyethyl esters of (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] nucleosides and evaluation of their mechanism of action
    Wendy C Magee
    Department of Medical Microbiology and Immunology, Li Ka Shing Institute of Virology, 6020 K, Katz Group Centre, University of Alberta, Edmonton, AB T6G 2E1, Canada
    Antimicrob Agents Chemother 55:5063-72. 2011

Collaborators

  • Michael D Hamilton
  • Don B Gammon
  • Chad R Irwin
  • Wendy C Magee
  • Li Qin
  • Chris Upton
  • Y C James Lin
  • Mary M Hitt
  • Nicole A Favis
  • Kate C Agopsowicz
  • Karl Y Hostetler
  • Bart Hazes
  • Douglas D Richman
  • Nadejda Valiaeva
  • James R Beadle
  • Graciela Andrei
  • Sophie Duraffour
  • Branawan Gowrishankar
  • Anthony A Nuara
  • R Mark Buller

Detail Information

Publications7

  1. pmc Enzymatic processing of replication and recombination intermediates by the vaccinia virus DNA polymerase
    Michael D Hamilton
    Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, The University of Alberta Edmonton, AB, Canada T6G 2H7
    Nucleic Acids Res 33:2259-68. 2005
    ....
  2. pmc Duplex strand joining reactions catalyzed by vaccinia virus DNA polymerase
    Michael D Hamilton
    Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, The University of Alberta, Edmonton, AB, Canada T6G 2H7
    Nucleic Acids Res 35:143-51. 2007
    ..Recombinant duplexes are the least favored ligands. These data suggest that a particular combination of otherwise ordinary enzymatic and DNA-binding properties, enable poxvirus DNA polymerases to promote duplex joining reactions...
  3. pmc Vaccinia virus-encoded ribonucleotide reductase subunits are differentially required for replication and pathogenesis
    Don B Gammon
    Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada
    PLoS Pathog 6:e1000984. 2010
    ....
  4. pmc Myxoma virus oncolytic efficiency can be enhanced through chemical or genetic disruption of the actin cytoskeleton
    Chad R Irwin
    Department of Medical Microbiology and Immunology, University of Alberta, Edmonton Alberta, Canada
    PLoS ONE 8:e84134. 2013
    ..Furthermore, since all viruses must overcome barriers to exit posed by structures like cortical actin, these findings suggest that the oncolytic activity of other viruses may be enhanced through similar strategies. ..
  5. pmc Genomic analysis of the vaccinia virus strain variants found in Dryvax vaccine
    Li Qin
    Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, 6020 Katz Group Centre, Edmonton, AB T6G 2H7, Canada
    J Virol 85:13049-60. 2011
    ..There is more genetic diversity detected within a vial of Dryvax than between variola virus major and minor strains, and our study highlights how propagation methods affect the genetics of orthopoxvirus populations...
  6. pmc Vaccinia virus particles mix inefficiently, and in a way that would restrict viral recombination, in coinfected cells
    Y C James Lin
    Alberta Institute for Viral Immunology and Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, The University of Alberta, Alberta, Canada
    J Virol 84:2432-43. 2010
    ..Our studies suggest that the intracellular movement and mixing of virosomes create constraints that reduce opportunities for forming recombinants and that these phenomena create outcomes reflected in classical poxvirus genetics...
  7. pmc Inhibition of HIV-1 by octadecyloxyethyl esters of (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] nucleosides and evaluation of their mechanism of action
    Wendy C Magee
    Department of Medical Microbiology and Immunology, Li Ka Shing Institute of Virology, 6020 K, Katz Group Centre, University of Alberta, Edmonton, AB T6G 2E1, Canada
    Antimicrob Agents Chemother 55:5063-72. 2011
    ..These results indicate that HPMPC and HPMPA inhibit HIV-1 by a complex mechanism and suggest that this class of drugs has a broader spectrum of activity than previously shown...