D T Eurich

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. pmc Benefits and harms of antidiabetic agents in patients with diabetes and heart failure: systematic review
    Dean T Eurich
    Institute of Health Economics, Edmonton, AB, Canada, T5J 3N4
    BMJ 335:497. 2007
  2. ncbi request reprint Cardiovascular medication utilization and adherence among adults living in rural and urban areas: a systematic review and meta-analysis
    Gaetanne K Murphy
    2 040 Li Ka Shing Center for Health Research Innovation, School of Public Health, University of Alberta, Edmonton, AB T6G 2E1, Canada
    BMC Public Health 14:544. 2014
  3. pmc Urinary metabolomic signature of esophageal cancer and Barrett's esophagus
    Vanessa W Davis
    Department of Surgery, 2D2, 01 Walter Mackenzie Health Sciences Center, University of Alberta, 8440 112th Street, Edmonton, Alberta T6G 2B7, Canada
    World J Surg Oncol 10:271. 2012
  4. doi request reprint Comparative safety and effectiveness of metformin in patients with diabetes mellitus and heart failure: systematic review of observational studies involving 34,000 patients
    Dean T Eurich
    Department of Public Health Sciences, School of Public Health, Li Ka Shing Center, University of Alberta, Edmonton, Alberta, Canada
    Circ Heart Fail 6:395-402. 2013
  5. pmc Comparative safety and effectiveness of sitagliptin in patients with type 2 diabetes: retrospective population based cohort study
    D T Eurich
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, AB, Canada T6G 2G3
    BMJ 346:f2267. 2013
  6. pmc Population-based cohort study of outpatients with pneumonia: rationale, design and baseline characteristics
    Dean T Eurich
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    BMC Infect Dis 12:135. 2012
  7. doi request reprint Pneumococcal vaccination and risk of acute coronary syndromes in patients with pneumonia: population-based cohort study
    Dean T Eurich
    Department of Public Health Sciences, School of PublicHealth, University of Alberta, Edmonton, Alberta, Canada
    Heart 98:1072-7. 2012
  8. pmc A pragmatic cluster randomized trial evaluating the impact of a community pharmacy intervention on statin adherence: rationale and design of the Community Pharmacy Assisting in Total Cardiovascular Health (CPATCH) study
    Charity D Evans
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada
    Trials 11:76. 2010
  9. ncbi request reprint Wrongfully accused: metformin use in heart failure
    Dean T Eurich
    School of Public Health, University of Alberta, Edmonton, AL, T6G 2T4, Canada
    Expert Rev Cardiovasc Ther 9:147-50. 2011
  10. doi request reprint Dysglycaemia and 90 day and 1 year risks of death or readmission in patients hospitalised for community-acquired pneumonia
    D T Eurich
    Department of Public Health Sciences, School of Public Health, University of Alberta, 13 103 Clinical Sciences Bldg, Edmonton T6G 2G3 AB, Canada
    Diabetologia 53:497-503. 2010

Collaborators

Detail Information

Publications44

  1. pmc Benefits and harms of antidiabetic agents in patients with diabetes and heart failure: systematic review
    Dean T Eurich
    Institute of Health Economics, Edmonton, AB, Canada, T5J 3N4
    BMJ 335:497. 2007
    ..To review the literature on the association between antidiabetic agents and morbidity and mortality in people with heart failure and diabetes...
  2. ncbi request reprint Cardiovascular medication utilization and adherence among adults living in rural and urban areas: a systematic review and meta-analysis
    Gaetanne K Murphy
    2 040 Li Ka Shing Center for Health Research Innovation, School of Public Health, University of Alberta, Edmonton, AB T6G 2E1, Canada
    BMC Public Health 14:544. 2014
    ..Therefore we undertook a systematic review to determine if cardiovascular medication utilization and adherence patterns differ for rural versus urban patients...
  3. pmc Urinary metabolomic signature of esophageal cancer and Barrett's esophagus
    Vanessa W Davis
    Department of Surgery, 2D2, 01 Walter Mackenzie Health Sciences Center, University of Alberta, 8440 112th Street, Edmonton, Alberta T6G 2B7, Canada
    World J Surg Oncol 10:271. 2012
    ..Metabolomics provides a means for non- invasive screening of early tumor-associated perturbations in cellular metabolism...
  4. doi request reprint Comparative safety and effectiveness of metformin in patients with diabetes mellitus and heart failure: systematic review of observational studies involving 34,000 patients
    Dean T Eurich
    Department of Public Health Sciences, School of Public Health, Li Ka Shing Center, University of Alberta, Edmonton, Alberta, Canada
    Circ Heart Fail 6:395-402. 2013
    ..Therefore, we undertook a systematic review of the trial and nontrial evidence for metformin in patients with diabetes mellitus and HF...
  5. pmc Comparative safety and effectiveness of sitagliptin in patients with type 2 diabetes: retrospective population based cohort study
    D T Eurich
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, AB, Canada T6G 2G3
    BMJ 346:f2267. 2013
    ..To determine if the use of sitagliptin in newly treated patients with type 2 diabetes is associated with any changes in clinical outcomes...
  6. pmc Population-based cohort study of outpatients with pneumonia: rationale, design and baseline characteristics
    Dean T Eurich
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    BMC Infect Dis 12:135. 2012
    ..Few studies have been conducted in outpatients with pneumonia, and there is a paucity of data on short and long term morbidity or mortality and associated clinical correlates in this group of patients...
  7. doi request reprint Pneumococcal vaccination and risk of acute coronary syndromes in patients with pneumonia: population-based cohort study
    Dean T Eurich
    Department of Public Health Sciences, School of PublicHealth, University of Alberta, Edmonton, Alberta, Canada
    Heart 98:1072-7. 2012
    ..It is vigorously debated whether pneumococcal polysaccharide vaccination (PPV) reduces risk of acute coronary syndrome (ACS) events in patients with community-acquired pneumonia (CAP)...
  8. pmc A pragmatic cluster randomized trial evaluating the impact of a community pharmacy intervention on statin adherence: rationale and design of the Community Pharmacy Assisting in Total Cardiovascular Health (CPATCH) study
    Charity D Evans
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada
    Trials 11:76. 2010
    ..This novel design integrates cluster randomization and an outcome evaluation of medication adherence using a population-based administrative data source in the province of Saskatchewan, Canada...
  9. ncbi request reprint Wrongfully accused: metformin use in heart failure
    Dean T Eurich
    School of Public Health, University of Alberta, Edmonton, AL, T6G 2T4, Canada
    Expert Rev Cardiovasc Ther 9:147-50. 2011
    ..This article will review a recent observational study by Aguilar et al. published in Circulation - Heart Failure that reported improved outcomes associated with metformin therapy in patients with diabetes and heart failure...
  10. doi request reprint Dysglycaemia and 90 day and 1 year risks of death or readmission in patients hospitalised for community-acquired pneumonia
    D T Eurich
    Department of Public Health Sciences, School of Public Health, University of Alberta, 13 103 Clinical Sciences Bldg, Edmonton T6G 2G3 AB, Canada
    Diabetologia 53:497-503. 2010
    ..The aim of this study was to investigate whether dysglycaemia at admission is associated with adverse events at 90 days or 1 year in a population-based cohort of patients hospitalised with community-acquired pneumonia (CAP)...
  11. pmc The darkening cloud of diabetes: do trends in cardiovascular risk management provide a silver lining?
    Dean T Eurich
    School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Diabetes Care 31:2136-42. 2008
    ..We aimed to evaluate the changes in cardiovascular-related health care utilization (drug therapies, hospitalizations) and mortality for the diabetic population during a 9-year period in Saskatchewan, Canada...
  12. pmc Metformin treatment in diabetes and heart failure: when academic equipoise meets clinical reality
    Dean T Eurich
    School of Public Health, University of Alberta, Edmonton, Alberta, T6G 2G3, Canada
    Trials 10:12. 2009
    ..Therefore, we attempted to conduct a pilot study to evaluate the feasibility of undertaking a large randomized controlled trial with clinical endpoints...
  13. doi request reprint Recurrent community-acquired pneumonia in patients starting acid-suppressing drugs
    Dean T Eurich
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Am J Med 123:47-53. 2010
    ..To test this hypothesis, we examined a prospective population-based cohort predisposed to pneumonia: elderly patients (> or =65 years) who had survived hospitalization for pneumonia...
  14. ncbi request reprint Mortality reduction with influenza vaccine in patients with pneumonia outside "flu" season: pleiotropic benefits or residual confounding?
    Dean T Eurich
    Department of Public Health Sciences, School of Public Health, University of Alberta, 13 103 Clinical Sciences Bldg, Edmonton, AB, T6G 2G3 Canada
    Am J Respir Crit Care Med 178:527-33. 2008
    ..Observational studies suggest a 50% mortality reduction for older patients receiving influenza vaccination; some deem this magnitude of benefit implausible and invoke confounding by the "healthy user effect" as an alternate explanation...
  15. pmc Assessing responsiveness of generic and specific health related quality of life measures in heart failure
    Dean T Eurich
    Institute of Health Economics, Edmonton, Alberta, Canada
    Health Qual Life Outcomes 4:89. 2006
    ..We compared the relative responsiveness of generic and heart failure specific HRQL instruments, as measured both by common psychometric indices and by external clinical criteria...
  16. pmc Obesity and outcomes in patients hospitalized with pneumonia
    S Kahlon
    Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, AB, Canada
    Clin Microbiol Infect 19:709-16. 2013
    ..This suggests a protective influence of BMIs > 30 kg/m(2) that requires better mechanistic understanding...
  17. pmc The effect of specialist care within the first year on subsequent outcomes in 24,232 adults with new-onset diabetes mellitus: population-based cohort study
    F A McAlister
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Qual Saf Health Care 16:6-11. 2007
    ..Although specialty care has been shown to improve short-term outcomes in patients hospitalised with acute medical conditions, its effect on patients with chronic conditions treated in the ambulatory care setting is less clear...
  18. ncbi request reprint Impact of guideline-concordant antibiotics and macrolide/β-lactam combinations in 3203 patients hospitalized with pneumonia: prospective cohort study
    L Asadi
    The Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Canada
    Clin Microbiol Infect 19:257-64. 2013
    ..Our findings do not support any clinical advantage of macrolide/β-lactam compared with respiratory fluoroquinolone monotherapy...
  19. doi request reprint Insulin use and increased risk of mortality in type 2 diabetes: a cohort study
    J M Gamble
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Diabetes Obes Metab 12:47-53. 2010
    ..To compare population-based rates of all-cause and cardiovascular (CV) mortality in newly treated patients with type 2 diabetes according to levels of insulin exposure...
  20. ncbi request reprint Improved clinical outcomes associated with metformin in patients with diabetes and heart failure
    Dean T Eurich
    Institute of Health Economics, Edmonton, Alberta, Canada
    Diabetes Care 28:2345-51. 2005
    ..The aim of this study was to evaluate the association between metformin and clinical outcomes in patients with heart failure and type 2 diabetes...
  21. ncbi request reprint The natural history of LDL control in type 2 diabetes: a prospective study of adherence to lipid guidelines
    Diana Rucker
    University of Alberta, 2E3 07 Walter Mackenzie Health Sciences Centre, University of Alberta Hospital, 8440 112th St, Edmonton, Alberta, Canada
    Diabetes Care 29:2506-8. 2006
  22. doi request reprint Long-term morbidity and mortality after hospitalization with community-acquired pneumonia: a population-based cohort study
    Jennie Johnstone
    Department of Medicine, Faculty of Medicine and Dentistry, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Medicine (Baltimore) 87:329-34. 2008
    ....
  23. ncbi request reprint Risk of heart failure in patients with recent-onset type 2 diabetes: population-based cohort study
    Alexander A Leung
    Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Alberta, Canada
    J Card Fail 15:152-7. 2009
    ..Although thiazolidinediones precipitate fluid retention in clinical trials, current guidelines advocate their use for patients with diabetes who are felt to be at low risk for heart failure (HF)...
  24. ncbi request reprint A multicenter disease management program for hospitalized patients with heart failure
    Ross T Tsuyuki
    Division of Cardiology and Department of Public Health Sciences, Faculty of Medicine and Dentistry, University of Alberta, 220 College Plaza, Edmonton, Canada T6G 2C8
    J Card Fail 10:473-80. 2004
    ..In this 2-stage, multicenter trial, we evaluated the effect of a disease management program on clinical and economic outcomes in patients with HF...
  25. ncbi request reprint Reduced mortality associated with the use of ACE inhibitors in patients with type 2 diabetes
    Dean T Eurich
    Institute of Health Economics 1200, 10405 Jasper Ave, Edmonton, Alberta, Canada T5J 3N4
    Diabetes Care 27:1330-4. 2004
    ..Subjects were prospectively followed until death or the end of 1999. Multivariate Cox proportional hazards models were used to assess differences in all-cause and cardiovascular-related mortality between cohort groups...
  26. pmc A meta-analysis of the association between adherence to drug therapy and mortality
    Scot H Simpson
    Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada T6G 2N8
    BMJ 333:15. 2006
    ..To evaluate the relation between adherence to drug therapy, including placebo, and mortality...
  27. ncbi request reprint Secondary failure rates associated with metformin and sulfonylurea therapy for type 2 diabetes mellitus
    Dean T Eurich
    Institute of Health Economics, Edmonton, Alberta, Canada
    Pharmacotherapy 25:810-6. 2005
    ..To determine whether metformin therapy, compared with sulfonylurea therapy, is associated with a delayed onset of secondary failure in patients with type 2 diabetes mellitus...
  28. pmc Statins and outcomes in patients admitted to hospital with community acquired pneumonia: population based prospective cohort study
    Sumit R Majumdar
    Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada
    BMJ 333:999. 2006
    ....
  29. ncbi request reprint Generalizability and persistence of a multifaceted intervention for improving quality of care for rural patients with type 2 diabetes
    Jeffrey A Johnson
    Institute of Health Economics, Department of Public Health Sciences, University of Alberta, 1200 10405 Jasper Ave, Edmonton, Alberta, Canada T5J 3N4
    Diabetes Care 28:783-8. 2005
    ..Most quality improvement efforts for type 2 diabetes have neglected cardiovascular risk factors and are limited by a lack of information about generalizability across settings or persistence of effect over time...
  30. doi request reprint The risk of heart failure in patients with type 2 diabetes treated with oral agent monotherapy
    Finlay A McAlister
    Division of General Internal Medicine, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Eur J Heart Fail 10:703-8. 2008
    ..To determine if the risk of developing heart failure (HF) is associated with the use of sulfonylurea or metformin in patients with diabetes...
  31. doi request reprint Age still matters: prognosticating short- and long-term mortality for critically ill patients with pneumonia
    Wendy I Sligl
    Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
    Crit Care Med 38:2126-32. 2010
    ..To determine the association between age and mortality in critically ill patients with pneumonia. We hypothesized that increasing age would be independently associated with both short- and long-term mortality...
  32. ncbi request reprint Effect of pneumococcal vaccination in hospitalized adults with community-acquired pneumonia
    Jennie Johnstone
    Department of Medicine, University of Alberta, 2E3 07 Walter Mackenzie Health Sciences Centre, University of Alberta Hospital, 8440 112th Street, Edmonton, Alberta, Canada
    Arch Intern Med 167:1938-43. 2007
    ..We tested this hypothesis using a population-based cohort of hospitalized patients with CAP...
  33. doi request reprint Only severely limited, premorbid functional status is associated with short- and long-term mortality in patients with pneumonia who are critically ill: a prospective observational study
    Wendy I Sligl
    Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada
    Chest 139:88-94. 2011
    ..We examined the association between premorbid functional status and mortality in patients with severe pneumonia...
  34. pmc Treatment of type 2 diabetes and outcomes in patients with heart failure: a nested case-control study from the U.K. General Practice Research Database
    Michael R MacDonald
    Golden Jubilee National Hospital, Glasgow, Scotland
    Diabetes Care 33:1213-8. 2010
    ..We designed this study to determine whether this association reflects a beneficial effect of metformin or a harmful effect of other agents...
  35. doi request reprint Oxygen saturations less than 92% are associated with major adverse events in outpatients with pneumonia: a population-based cohort study
    Sumit R Majumdar
    Department of Medicine, Faculty of Medicine and Dentistry, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Clin Infect Dis 52:325-31. 2011
    ..We sought evidence to support or refute the practice...
  36. doi request reprint Risk of acute coronary events associated with glyburide compared with gliclazide use in patients with type 2 diabetes: a nested case-control study
    A S Abdelmoneim
    Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
    Diabetes Obes Metab 16:22-9. 2014
    ..We hypothesized that the risk of acute coronary syndrome (ACS) events would be higher in patients using glyburide compared with gliclazide...
  37. pmc Dose-response relation between sulfonylurea drugs and mortality in type 2 diabetes mellitus: a population-based cohort study
    Scot H Simpson
    Institute of Health Economics, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alta
    CMAJ 174:169-74. 2006
    ..The purpose of this study was to determine if the risk of death changes with level of exposure to sulfonylurea drugs...
  38. doi request reprint Admission hypoglycemia and increased mortality in patients hospitalized with pneumonia
    John Michael Gamble
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Am J Med 123:556.e11-6. 2010
    ..The relationship between spontaneous admission hypoglycemia and mortality in patients hospitalized with community-acquired pneumonia is unclear...
  39. ncbi request reprint Post-thrombotic syndrome after total hip arthroplasty is uncommon
    Michael J Mant
    Department of Medicine, Division of Hematology and Oncology, University of Alberta, Edmonton, Canada
    Acta Orthop 79:794-9. 2008
    ..Deep vein thrombosis (DVT), usually asymptomatic, is common after total hip arthroplasty (THA). Post-thrombotic syndrome (PTS) is a potential late complication of DVT, but there is limited data on its occurrence...
  40. ncbi request reprint Atenolol as initial antihypertensive therapy: an observational study comparing first-line agents
    David F Blackburn
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    J Hypertens 25:1499-505. 2007
    ..The role of atenolol in the management of patients with hypertension is currently under scrutiny. Our aim was to evaluate the real-world consequences of recent clinical trial findings...
  41. ncbi request reprint Diabetes, fitness, and body mass index
    Steven T Johnson
    Arch Intern Med 166:1326-7; author reply 1327. 2006