Mitra Esfandiarei

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. ncbi request reprint Molecular biology and pathogenesis of viral myocarditis
    Mitra Esfandiarei
    The James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, St Paul s Hospital, Providence Health Care Research Institute, Vancouver, Canada
    Annu Rev Pathol 3:127-55. 2008
  2. ncbi request reprint Liposome-mediated transient transfection reduces cholesterol-dependent coxsackievirus infectivity
    Jerry Wong
    Department of Pathology and Laboratory Medicine, The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, University of British Columbia St Paul s Hospital, Vancouver, Canada
    J Virol Methods 133:211-8. 2006
  3. ncbi request reprint Novel role for integrin-linked kinase in modulation of coxsackievirus B3 replication and virus-induced cardiomyocyte injury
    Mitra Esfandiarei
    The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research Providence Health Care Research Institute, Vancouver, British Columbia, Canada
    Circ Res 99:354-61. 2006
  4. ncbi request reprint Coxsackievirus B3 activates nuclear factor kappa B transcription factor via a phosphatidylinositol-3 kinase/protein kinase B-dependent pathway to improve host cell viability
    Mitra Esfandiarei
    The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Providence Health Care Research Institute St Paul s Hospital, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada
    Cell Microbiol 9:2358-71. 2007
  5. ncbi request reprint Regulation of the versican promoter by the beta-catenin-T-cell factor complex in vascular smooth muscle cells
    Maziar Rahmani
    James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, St Paul s Hospital, 1081 Burrard Street, Vancouver, British Columbia V6Z 1Y6, Canada
    J Biol Chem 280:13019-28. 2005
  6. pmc Stress-activated protein kinases are involved in coxsackievirus B3 viral progeny release
    Xiaoning Si
    Department of Pathology and Laboratory Medicine, The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, University of British Columbia St Paul s Hospital, Vancouver, British Columbia, Canada
    J Virol 79:13875-81. 2005
  7. doi request reprint Diosgenin modulates vascular smooth muscle cell function by regulating cell viability, migration, and calcium homeostasis
    Mitra Esfandiarei
    Child and Family Research Institute, Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, BC, Canada
    J Pharmacol Exp Ther 336:925-39. 2011
  8. pmc Integrin-linked kinase functions as a downstream signal of platelet-derived growth factor to regulate actin polymerization and vascular smooth muscle cell migration
    Mitra Esfandiarei
    Child and Family Research Institute, Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, BC, Canada
    BMC Cell Biol 11:16. 2010
  9. pmc Waves of calcium depletion in the sarcoplasmic reticulum of vascular smooth muscle cells: an inside view of spatiotemporal Ca2+ regulation
    Mitra Esfandiarei
    Child and Family Research Institute, Department of Anaesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 8:e55333. 2013
  10. pmc Coxsackievirus B3 replication is reduced by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway
    Honglin Luo
    Department of Pathology and Laboratory Medicine, McDonald Research Laboratories The iCAPTURE Center, St Paul s Hospital Providence Health Care University of British Columbia, Vancouver, British Columbia, Canada
    J Virol 76:3365-73. 2002

Collaborators

  • Bruce M McManus
  • Honglin Luo
  • Nicola Fameli
  • Decheng Yang
  • Xiaoning Si
  • Jerry Wong
  • Jingchun Zhang
  • Caroline Cheung
  • Agripina Suarez
  • Guang Gao
  • Maziar Rahmani
  • Andrew Morgan
  • Ji Yuan
  • Bobby Yanagawa
  • Christopher M Carthy
  • Yahong Wang
  • Jon M Carthy
  • Brian W Wong
  • Zongshu Luo
  • Jason T Read
  • Paul C McDonald
  • Paul S Rennie
  • Craig B Thompson
  • Charles M Rudin
  • David J Granville
  • David W C Hunt
  • Paul Cheung

Detail Information

Publications13

  1. ncbi request reprint Molecular biology and pathogenesis of viral myocarditis
    Mitra Esfandiarei
    The James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, St Paul s Hospital, Providence Health Care Research Institute, Vancouver, Canada
    Annu Rev Pathol 3:127-55. 2008
    ..Advances in genomics and proteomics, and in the use of informatics and biostatistics, are allowing unbiased initial evaluations that can be the basis for testable hypotheses about virus pathogenesis and new therapies...
  2. ncbi request reprint Liposome-mediated transient transfection reduces cholesterol-dependent coxsackievirus infectivity
    Jerry Wong
    Department of Pathology and Laboratory Medicine, The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, University of British Columbia St Paul s Hospital, Vancouver, Canada
    J Virol Methods 133:211-8. 2006
    ..Our data suggest that liposome-mediated cDNA transient transfection inhibits coxsackievirus infectivity via inhibition of viral attachment, which is likely occurring through the changes of membrane cholesterol integrity...
  3. ncbi request reprint Novel role for integrin-linked kinase in modulation of coxsackievirus B3 replication and virus-induced cardiomyocyte injury
    Mitra Esfandiarei
    The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research Providence Health Care Research Institute, Vancouver, British Columbia, Canada
    Circ Res 99:354-61. 2006
    ....
  4. ncbi request reprint Coxsackievirus B3 activates nuclear factor kappa B transcription factor via a phosphatidylinositol-3 kinase/protein kinase B-dependent pathway to improve host cell viability
    Mitra Esfandiarei
    The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Providence Health Care Research Institute St Paul s Hospital, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada
    Cell Microbiol 9:2358-71. 2007
    ..However, a prolonged treatment has a detrimental effect on cells, indicating the existence of a delicate balance between the anti- and pro-apoptotic roles of TNF-alpha in the setting of CVB3 infection...
  5. ncbi request reprint Regulation of the versican promoter by the beta-catenin-T-cell factor complex in vascular smooth muscle cells
    Maziar Rahmani
    James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, St Paul s Hospital, 1081 Burrard Street, Vancouver, British Columbia V6Z 1Y6, Canada
    J Biol Chem 280:13019-28. 2005
    ....
  6. pmc Stress-activated protein kinases are involved in coxsackievirus B3 viral progeny release
    Xiaoning Si
    Department of Pathology and Laboratory Medicine, The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, University of British Columbia St Paul s Hospital, Vancouver, British Columbia, Canada
    J Virol 79:13875-81. 2005
    ..We conclude that SAPK pathways play critical roles in the life cycle of CVB3, particularly in viral progeny release...
  7. doi request reprint Diosgenin modulates vascular smooth muscle cell function by regulating cell viability, migration, and calcium homeostasis
    Mitra Esfandiarei
    Child and Family Research Institute, Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, BC, Canada
    J Pharmacol Exp Ther 336:925-39. 2011
    ....
  8. pmc Integrin-linked kinase functions as a downstream signal of platelet-derived growth factor to regulate actin polymerization and vascular smooth muscle cell migration
    Mitra Esfandiarei
    Child and Family Research Institute, Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, BC, Canada
    BMC Cell Biol 11:16. 2010
    ..However, the regulatory role of ILK during vascular smooth muscle cell migration and the importance of integrin signaling in occlusive vascular diseases are not yet fully elucidated...
  9. pmc Waves of calcium depletion in the sarcoplasmic reticulum of vascular smooth muscle cells: an inside view of spatiotemporal Ca2+ regulation
    Mitra Esfandiarei
    Child and Family Research Institute, Department of Anaesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 8:e55333. 2013
    ..Finally, our observation that the depletion wave was arrested by the nuclear envelope may have implications for selective Ca2+ signalling...
  10. pmc Coxsackievirus B3 replication is reduced by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway
    Honglin Luo
    Department of Pathology and Laboratory Medicine, McDonald Research Laboratories The iCAPTURE Center, St Paul s Hospital Providence Health Care University of British Columbia, Vancouver, British Columbia, Canada
    J Virol 76:3365-73. 2002
    ..Our findings demonstrate coxsackievirus takeover of a particular host signaling mechanism and uncover a prospective approach to stymie virus spread and preserve myocardial integrity...
  11. pmc Protein kinase B/Akt regulates coxsackievirus B3 replication through a mechanism which is not caspase dependent
    Mitra Esfandiarei
    The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Department of Pathology and Laboratory Medicine, St Paul s Hospital Providence Health Care University of British Columbia, Vancouver, Canada
    J Virol 78:4289-98. 2004
    ..Taken together, these data illustrate a new and imperative role for Akt in CVB3 infection in HeLa cells and show that the PI3K/Akt signaling is beneficial to CVB3 replication...
  12. pmc Pyrrolidine dithiocarbamate reduces coxsackievirus B3 replication through inhibition of the ubiquitin-proteasome pathway
    Xiaoning Si
    Department of Pathology and Laboratory Medicine, The James HoggiCAPTURE Centre for Cardiovascular and Pulmonary Research, University of British Columbia St Paul s Hospital, Vancouver, British Columbia, Canada V6Z 1Y6
    J Virol 79:8014-23. 2005
    ..Zhang, C. Cheung, A. Suarez, B. M. McManus, and D. Yang, Am. J. Pathol. 163:381-385, 2003), results in this study suggest a strong antiviral effect of PDTC on coxsackievirus, likely through inhibition of the ubiquitin-proteasome pathway...
  13. ncbi request reprint Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection
    Christopher M Carthy
    Department of Pathology and Laboratory Medicine, University of British Columbia St Paul s Hospital, The iCAPTUR4E Centre McDonald Research Laboratories, 1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6
    Virology 313:147-57. 2003
    ..Our data suggest that mitochondrial release of cytochrome c may be an important early event in caspase activation in CVB3 infection, and, as such, may contribute to the loss of host-cell viability and progeny virus release...