Irina Dinu

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. pmc Linear combination test for gene set analysis of a continuous phenotype
    Irina Dinu
    School of Public Health, University of Alberta, Edmonton, Alberta T6G 1C9, Canada
    BMC Bioinformatics 14:212. 2013
  2. pmc Gene-set analysis and reduction
    Irina Dinu
    PhD, School of Public Health, University of Alberta, 13 106J Clinical Sciences Building, Edmonton, Alberta T6G2G3, Canada
    Brief Bioinform 10:24-34. 2009
  3. pmc Improving gene set analysis of microarray data by SAM-GS
    Irina Dinu
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    BMC Bioinformatics 8:242. 2007
  4. pmc Comparative evaluation of gene-set analysis methods
    Qi Liu
    School of Public Health, University of Alberta, Edmonton, Alberta, T6G2G3, Canada
    BMC Bioinformatics 8:431. 2007
  5. doi request reprint Sepsis After Cardiac Surgery Early in Infancy and Adverse 4.5-Year Neurocognitive Outcomes
    Naveen Sidhu
    Division of Pediatric Critical Care, Department of Pediatrics, University of Alberta and Stollery Children s Hospital, Edmonton, Alberta, Canada N S, A R J
    J Am Heart Assoc 4:e001954. 2015
  6. doi request reprint The effects of modified spaced-retrieval training on learning and retention of face-name associations by individuals with dementia
    Tammy Hopper
    Department of Speech Pathology and Audiology, University of Alberta, Edmonton, Alberta, Canada
    Neuropsychol Rehabil 20:81-102. 2010
  7. ncbi request reprint Linear combination test for hierarchical gene set analysis
    Xiaoming Wang
    University of Alberta
    Stat Appl Genet Mol Biol 10:Article 13. 2011
  8. ncbi request reprint A multi-centre evaluation of the RIFLE criteria for early acute kidney injury in critically ill patients
    Sean M Bagshaw
    Division of Critical Care Medicine, University of Alberta Hospital, 3C1 16 Walter C Mackenzie Centre, 8440 122 Street, Edmonton, Alberta T6G2B7, Canada
    Nephrol Dial Transplant 23:1203-10. 2008
  9. pmc Gene set enrichment analysis for multiple continuous phenotypes
    Xiaoming Wang
    School of Public Health, University of Alberta, Edmonton, AB T6G 1C9, Canada
    BMC Bioinformatics 15:260. 2014
  10. doi request reprint Prediction of preschool functional abilities after early complex cardiac surgery
    Gwen Y Alton
    1Glenrose Rehabilitation Hospital, Edmonton, Alberta, Canada
    Cardiol Young 25:655-62. 2015

Detail Information

Publications15

  1. pmc Linear combination test for gene set analysis of a continuous phenotype
    Irina Dinu
    School of Public Health, University of Alberta, Edmonton, Alberta T6G 1C9, Canada
    BMC Bioinformatics 14:212. 2013
    ....
  2. pmc Gene-set analysis and reduction
    Irina Dinu
    PhD, School of Public Health, University of Alberta, 13 106J Clinical Sciences Building, Edmonton, Alberta T6G2G3, Canada
    Brief Bioinform 10:24-34. 2009
    ..Codes to implement SAM-GSR in the statistical package R can be downloaded from http://www.ualberta.ca/~yyasui/homepage.html...
  3. pmc Improving gene set analysis of microarray data by SAM-GS
    Irina Dinu
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    BMC Bioinformatics 8:242. 2007
    ..We describe here some critical problems with GSEA and propose an alternative method by extending the individual-gene analysis method, Significance Analysis of Microarray (SAM), to gene-set analyses (SAM-GS)...
  4. pmc Comparative evaluation of gene-set analysis methods
    Qi Liu
    School of Public Health, University of Alberta, Edmonton, Alberta, T6G2G3, Canada
    BMC Bioinformatics 8:431. 2007
    ..subject sampling. The three methods were compared based on a simulation experiment and analyses of three real-world microarray datasets...
  5. doi request reprint Sepsis After Cardiac Surgery Early in Infancy and Adverse 4.5-Year Neurocognitive Outcomes
    Naveen Sidhu
    Division of Pediatric Critical Care, Department of Pediatrics, University of Alberta and Stollery Children s Hospital, Edmonton, Alberta, Canada N S, A R J
    J Am Heart Assoc 4:e001954. 2015
    ..We aimed to determine whether sepsis is associated with neurocognitive outcomes 4.5 years after congenital heart disease surgery in early infancy...
  6. doi request reprint The effects of modified spaced-retrieval training on learning and retention of face-name associations by individuals with dementia
    Tammy Hopper
    Department of Speech Pathology and Audiology, University of Alberta, Edmonton, Alberta, Canada
    Neuropsychol Rehabil 20:81-102. 2010
    ..Theoretical and clinical implications are discussed...
  7. ncbi request reprint Linear combination test for hierarchical gene set analysis
    Xiaoming Wang
    University of Alberta
    Stat Appl Genet Mol Biol 10:Article 13. 2011
    ....
  8. ncbi request reprint A multi-centre evaluation of the RIFLE criteria for early acute kidney injury in critically ill patients
    Sean M Bagshaw
    Division of Critical Care Medicine, University of Alberta Hospital, 3C1 16 Walter C Mackenzie Centre, 8440 122 Street, Edmonton, Alberta T6G2B7, Canada
    Nephrol Dial Transplant 23:1203-10. 2008
    ..We sought to evaluate the RIFLE criteria on the day of ICU admission in a large heterogenous population of critically ill patients...
  9. pmc Gene set enrichment analysis for multiple continuous phenotypes
    Xiaoming Wang
    School of Public Health, University of Alberta, Edmonton, AB T6G 1C9, Canada
    BMC Bioinformatics 15:260. 2014
    ..While GSA methods on a single binary or categorical phenotype abounds, little attention has been paid to the case of a continuous phenotype, and there is no method to accommodate correlated multiple continuous phenotypes...
  10. doi request reprint Prediction of preschool functional abilities after early complex cardiac surgery
    Gwen Y Alton
    1Glenrose Rehabilitation Hospital, Edmonton, Alberta, Canada
    Cardiol Young 25:655-62. 2015
    ..The purpose of this study is to determine potentially modifiable predictor variables of functional abilities in pre-school children who underwent complex cardiac surgery at 6 weeks of age or earlier...
  11. pmc SNP-SNP interactions discovered by logic regression explain Crohn's disease genetics
    Irina Dinu
    School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    PLoS ONE 7:e43035. 2012
    ..R codes, data examples, and a ReadMe file are available for download from our website: http://www.ualberta.ca/~yyasui/homepage.html...
  12. doi request reprint Can Public Health Risk Assessment Using Risk Matrices Be Misleading?
    Shabnam Vatanpour
    School of Public Health, University of Alberta, Edmonton, AB T6G 1C9, Canada
    Int J Environ Res Public Health 12:9575-88. 2015
    ..This method should not be abandoned wholesale, but users must address the source of the problem, apply the risk matrix with a full understanding of this problem and use matrix predictions to inform, but not drive decision-making. ..
  13. doi request reprint Neurocognitive outcomes at kindergarten entry after surgical repair of total anomalous pulmonary venous connection in early infancy
    Jonathan P Duff
    Department of Pediatrics, University of Alberta, Edmonton, AB, Canada
    Pediatr Cardiol 36:350-7. 2015
    ..Original peoples account for an unexpected proportion of patients (42%) and have a higher mortality...
  14. ncbi request reprint Prediction of second malignant neoplasm incidence in a large cohort of long-term survivors of childhood cancers
    Irina Dinu
    Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Blood Cancer 50:1026-31. 2008
    ..The ability to predict adverse-event occurrences accurately in long-term survivors of childhood cancer is of high importance in late effects research, both clinically and methodologically...
  15. ncbi request reprint Genotype-phenotype correlations in Axenfeld-Rieger malformation and glaucoma patients with FOXC1 and PITX2 mutations
    M Hermina Strungaru
    Department of Medical Genetics, University of Alberta, Edmonton, AB, Canada
    Invest Ophthalmol Vis Sci 48:228-37. 2007
    ..To improve the understanding of Axenfeld-Rieger Malformation (ARM)-associated glaucoma and to determine the best glaucoma treatment for patients with ARM who have known genetic defects in FOXC1 or PITX2...