- The biological basis for modern treatment of chordomaRoberto Jose Diaz
Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, ON, Canada
J Neurooncol 104:411-22. 2011..The authors review the current state of knowledge regarding chordoma and offer insight into potential new therapies for this rare and challenging tumor...
- Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastomaRoberto Jose Diaz
The Hospital for Sick Children Arthur and Sonia Labatt Brain Tumour Research Centre, Toronto, Ontario, Canada
Oncotarget 6:3359-74. 2015..Our results suggest the potential for therapeutic application of Aurora kinase B inhibitors in the treatment of Group 3 medulloblastoma. ..
- High-resolution whole-genome analysis of skull base chordomas implicates FHIT loss in chordoma pathogenesisRoberto Jose Diaz
Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada
Neoplasia 14:788-98. 2012..The finding that FHIT is lost in a majority of chordomas provides new insight into chordoma pathogenesis and points to a potential new therapeutic target for this challenging neoplasm...