Mary Jane De Souza

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Severity of energy-related menstrual disturbances increases in proportion to indices of energy conservation in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Science, University of Toronto, Toronto, Ontario, Canada
    Fertil Steril 88:971-5. 2007
  2. ncbi request reprint Fasting ghrelin levels in physically active women: relationship with menstrual disturbances and metabolic hormones
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, 55 Harbord Street, Toronto, Ontario, Canada M5S 2W6
    J Clin Endocrinol Metab 89:3536-42. 2004
  3. ncbi request reprint Luteal phase deficiency in recreational runners: evidence for a hypometabolic state
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada M5S 2W6
    J Clin Endocrinol Metab 88:337-46. 2003
  4. ncbi request reprint Menstrual disturbances in athletes: a focus on luteal phase defects
    Mary Jane De Souza
    Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada
    Med Sci Sports Exerc 35:1553-63. 2003
  5. ncbi request reprint Drive for thinness score is a proxy indicator of energy deficiency in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ont, Canada
    Appetite 48:359-67. 2007
  6. ncbi request reprint Physiological aspects and clinical sequelae of energy deficiency and hypoestrogenism in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada
    Hum Reprod Update 10:433-48. 2004
  7. ncbi request reprint The presence of both an energy deficiency and estrogen deficiency exacerbate alterations of bone metabolism in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
    Bone 43:140-8. 2008
  8. doi request reprint Elevated PYY is associated with energy deficiency and indices of subclinical disordered eating in exercising women with hypothalamic amenorrhea
    Jennifer L Scheid
    Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Science, University of Toronto, Toronto, Ontario, Canada M5S 2W6
    Appetite 52:184-92. 2009
  9. doi request reprint The effect of exercise and estrogen on osteoprotegerin in premenopausal women
    Sarah L West
    Department of Exercise Science, University of Toronto, Toronto, Ontario, Canada
    Bone 44:137-44. 2009
  10. doi request reprint Relationships between vascular resistance and energy deficiency, nutritional status and oxidative stress in oestrogen deficient physically active women
    Emma O'Donnell
    Cardiovascular Regulation Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
    Clin Endocrinol (Oxf) 70:294-302. 2009

Detail Information

Publications27

  1. ncbi request reprint Severity of energy-related menstrual disturbances increases in proportion to indices of energy conservation in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Science, University of Toronto, Toronto, Ontario, Canada
    Fertil Steril 88:971-5. 2007
    ..These data provide further evidence of the tight association between energy balance and reproduction and suggest that subtle declines in energy availability can produce clinically recognized menstrual disturbances...
  2. ncbi request reprint Fasting ghrelin levels in physically active women: relationship with menstrual disturbances and metabolic hormones
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, 55 Harbord Street, Toronto, Ontario, Canada M5S 2W6
    J Clin Endocrinol Metab 89:3536-42. 2004
    ....
  3. ncbi request reprint Luteal phase deficiency in recreational runners: evidence for a hypometabolic state
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada M5S 2W6
    J Clin Endocrinol Metab 88:337-46. 2003
    ..These alterations may represent a metabolic adaptation to an intermittent short-term negative energy balance...
  4. ncbi request reprint Menstrual disturbances in athletes: a focus on luteal phase defects
    Mary Jane De Souza
    Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada
    Med Sci Sports Exerc 35:1553-63. 2003
    ..The high prevalence of LPD warrants further investigation to assess health risks and preventive strategies...
  5. ncbi request reprint Drive for thinness score is a proxy indicator of energy deficiency in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ont, Canada
    Appetite 48:359-67. 2007
    ....
  6. ncbi request reprint Physiological aspects and clinical sequelae of energy deficiency and hypoestrogenism in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada
    Hum Reprod Update 10:433-48. 2004
    ..This paper critically reviews the physiological aspects and clinical sequelae of energy deficiency and hypoestrogenism associated with the female athlete triad in exercising women...
  7. ncbi request reprint The presence of both an energy deficiency and estrogen deficiency exacerbate alterations of bone metabolism in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
    Bone 43:140-8. 2008
    ..Bone loss in amenorrheic athletes has been attributed to energy deficiency-related suppression of bone formation, but not increased resorption despite hypoestrogenism...
  8. doi request reprint Elevated PYY is associated with energy deficiency and indices of subclinical disordered eating in exercising women with hypothalamic amenorrhea
    Jennifer L Scheid
    Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Science, University of Toronto, Toronto, Ontario, Canada M5S 2W6
    Appetite 52:184-92. 2009
    ..In conclusion, fasting PYY and ghrelin concentrations are elevated in exercising women with FHA and both gastrointestinal peptides may serve as a proxy indicator of energy deficiency in this population...
  9. doi request reprint The effect of exercise and estrogen on osteoprotegerin in premenopausal women
    Sarah L West
    Department of Exercise Science, University of Toronto, Toronto, Ontario, Canada
    Bone 44:137-44. 2009
    ..The benefits of exercise are widely recognized, however physically active women can develop exercise associated menstrual cycle disturbances such as amenorrhea (i.e., estrogen deficiency) secondary to a chronic energy deficiency...
  10. doi request reprint Relationships between vascular resistance and energy deficiency, nutritional status and oxidative stress in oestrogen deficient physically active women
    Emma O'Donnell
    Cardiovascular Regulation Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
    Clin Endocrinol (Oxf) 70:294-302. 2009
    ..We investigated whether other energy deficiency-associated factors might also be associated with altered cardiovascular function in these women...
  11. doi request reprint Cognitive dietary restraint: impact on bone, menstrual and metabolic status in young women
    Jason D Vescovi
    Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Sciences, University of Toronto, Toronto, ON, Canada M5S 2WS
    Physiol Behav 95:48-55. 2008
    ..A greater frequency of menstrual disturbances in women with higher CDR scores likely played a role in the reduced total body and lumbar spine BMD...
  12. ncbi request reprint Beyond hypoestrogenism in amenorrheic athletes: energy deficiency as a contributing factor for bone loss
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, 55 Harbord Street, Toronto, Ontario, M5S 2W6, Canada
    Curr Sports Med Rep 4:38-44. 2005
    ..These hormones (IGF-1 and leptin) play an important role in modulating bone turnover and bone mineral density in these women...
  13. doi request reprint Short-term response of bone turnover to low-dose oral contraceptives in exercising women with hypothalamic amenorrhea
    Jason D Vescovi
    Women s Exercise and Bone Health Laboratory, Department of Exercise Science, University of Toronto, Toronto, ON, Canada
    Contraception 77:97-104. 2008
    ..We examined the response of bone turnover markers and indices of energy status after 2 weeks of oral contraceptive (OC) therapy in premenopausal women with exercise-associated menstrual disturbances (EAMD)...
  14. doi request reprint Increased serum adiponectin concentrations in amenorrheic physically active women are associated with impaired bone health but not with estrogen exposure
    Emma O'Donnell
    Cardiovascular Research Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada M5S 2W6
    Bone 48:760-7. 2011
    ..The role of adiponectin in mediating gonadal status and bone health in weight-stable healthy adult female athletes with secondary amenorrhea has not yet been described...
  15. ncbi request reprint Long-term estrogen deficiency lowers regional blood flow, resting systolic blood pressure, and heart rate in exercising premenopausal women
    Paula J Harvey
    Women s Exercise and Bone Health Laboratory, Department of Medicine, University of Toronto, University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada
    Am J Physiol Endocrinol Metab 292:E1401-9. 2007
    ..These cardiovascular alterations represent markers of altered vascular function and autonomic regulation of which the long-term effects remain unknown...
  16. ncbi request reprint The cardiovascular effects of chronic hypoestrogenism in amenorrhoeic athletes: a critical review
    Emma O'Donnell
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada
    Sports Med 34:601-27. 2004
    ..Future research should focus on the presentation and progression of these adverse cardiovascular parameters in physically active women and athletes with hypoestrogenism to determine their effects on long-term health...
  17. doi request reprint The role of ovarian steroid hormones in mood
    Deborah H Schwartz
    Department of Psychology, University of Toronto, Canada
    Horm Behav 62:448-54. 2012
    ..Thus, fluctuations in ovarian hormones do not contribute significantly to daily mood in healthy women...
  18. doi request reprint Oligomenorrhoea in exercising women: a polycystic ovarian syndrome phenotype or distinct entity?
    Susan Awdishu
    Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
    Sports Med 39:1055-69. 2009
    ..Further investigation is necessary to explore whether different endocrine aetiologies underly menstrual disturbances, particularly oligomenorrhoea, in physically active women...
  19. doi request reprint 2014 Female Athlete Triad Coalition consensus statement on treatment and return to play of the female athlete triad: 1st International Conference held in San Francisco, CA, May 2012, and 2nd International Conference held in Indianapolis, IN, May 2013
    Mary Jane De Souza
    Penn State University, Department of Kinesiology, University Park, Pennsylvania University of California Los Angeles, Los Angeles, California Intermountain Healthcare, Salt Lake City, Utah Harvard Medical School, Boston, Massachusetts University of Waterloo, Waterloo, Ontario, Canada University of Toronto, Toronto, Ontario, Canada Hospital for Special Surgery, New York, New York Stanford University, Stanford, California
    Clin J Sport Med 24:96-119. 2014
    ....
  20. ncbi request reprint Effect of high dietary restraint on energy availability and menstrual status
    Jenna C Gibbs
    Department of Kinesiology, The Pennsylvania State University, University Park, PA, USA
    Med Sci Sports Exerc 45:1790-7. 2013
    ..Dietary restraint (DR) is a key eating behavior associated with menstrual disturbances (MD) in exercising women. However, the association between DR and energy availability (EA) has not been examined...
  21. ncbi request reprint Factors influencing exercise participation by older adults requiring chronic hemodialysis: a qualitative study
    Pia C Kontos
    Toronto Rehabilitation Institute, 11035 550 University Ave, Toronto, ON, Canada, M5G 2A2
    Int Urol Nephrol 39:1303-11. 2007
    ..A shift is required in the culture of ESRD treatment programs towards a wellness perspective that includes expectations of exercise encouragement by the health care team and participation by patients...
  22. ncbi request reprint Effects of lifetime exercise on the outcome of in vitro fertilization
    Anne B Loucks
    Obstet Gynecol 109:456-7. 2007
  23. ncbi request reprint Female athlete triad errors and misunderstandings
    Nancy I Williams
    Med Sci Sports Exerc 38:1021; author reply 1022. 2006
  24. ncbi request reprint Serum creatine kinase activity varies with ovulatory status in regularly exercising, premenopausal women
    Heather S Thompson
    Molecular and Cellular Biology Program, University of Massachusetts, Amherst, Mass, USA
    Horm Res 65:151-8. 2006
    ....
  25. ncbi request reprint Heat acclimation and physical training adaptations of young women using different contraceptive hormones
    Lawrence E Armstrong
    Human Performance Laboratory, Department of Kinesiology, University of Conneticut, Unit 1110, 2095 Hillside Road, Storrs, CT 06269 1110, USA
    Am J Physiol Endocrinol Metab 288:E868-75. 2005
    ....
  26. ncbi request reprint Temperature regulation during rest and exercise in the cold in premenarcheal and menarcheal girls
    Panagiota Klentrou
    Faculty of Applied Health Sciences, Brock University, Ontario, Canada L2S 3A1
    J Appl Physiol (1985) 96:1393-8. 2004
    ....
  27. ncbi request reprint Daily physical movement and bone mineral density among a mixed racial cohort of women
    Linda S Pescatello
    Center of Health Promotion, University of Connecticut, School of Allied Health, 358 Mansfield Road, U 2101, Storrs, CT 06269 2101, USA
    Med Sci Sports Exerc 34:1966-70. 2002
    ..We examined the influence of physical activities typical of everyday life on BMD among 151 women (52.0 +/- 0.9 yr). These women were of low socioeconomic status, and 57.6% were Hispanic, 17.2% black, and 24.5% white...