Research Topics
Genomes and GenesSpecies | Mary Jane De SouzaSummaryAffiliation: University of Toronto Country: Canada Publications
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Publications
Severity of energy-related menstrual disturbances increases in proportion to indices of energy conservation in exercising womenMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Science, University of Toronto, Toronto, Ontario, Canada
Fertil Steril 88:971-5. 2007..These data provide further evidence of the tight association between energy balance and reproduction and suggest that subtle declines in energy availability can produce clinically recognized menstrual disturbances...- Luteal phase deficiency in recreational runners: evidence for a hypometabolic stateMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada M5S 2W6
J Clin Endocrinol Metab 88:337-46. 2003..These alterations may represent a metabolic adaptation to an intermittent short-term negative energy balance... - Menstrual disturbances in athletes: a focus on luteal phase defectsMary Jane De Souza
Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada
Med Sci Sports Exerc 35:1553-63. 2003..The high prevalence of LPD warrants further investigation to assess health risks and preventive strategies... 
The presence of both an energy deficiency and estrogen deficiency exacerbate alterations of bone metabolism in exercising womenMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
Bone 43:140-8. 2008..Bone loss in amenorrheic athletes has been attributed to energy deficiency-related suppression of bone formation, but not increased resorption despite hypoestrogenism...- Physiological aspects and clinical sequelae of energy deficiency and hypoestrogenism in exercising womenMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada
Hum Reprod Update 10:433-48. 2004..This paper critically reviews the physiological aspects and clinical sequelae of energy deficiency and hypoestrogenism associated with the female athlete triad in exercising women... - Fasting ghrelin levels in physically active women: relationship with menstrual disturbances and metabolic hormonesMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, 55 Harbord Street, Toronto, Ontario, Canada M5S 2W6
J Clin Endocrinol Metab 89:3536-42. 2004.... - Drive for thinness score is a proxy indicator of energy deficiency in exercising womenMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ont, Canada
Appetite 48:359-67. 2007.... - Elevated PYY is associated with energy deficiency and indices of subclinical disordered eating in exercising women with hypothalamic amenorrheaJennifer L Scheid
Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Science, University of Toronto, Toronto, Ontario, Canada M5S 2W6
Appetite 52:184-92. 2009..In conclusion, fasting PYY and ghrelin concentrations are elevated in exercising women with FHA and both gastrointestinal peptides may serve as a proxy indicator of energy deficiency in this population... - The effect of exercise and estrogen on osteoprotegerin in premenopausal womenSarah L West
Department of Exercise Science, University of Toronto, Toronto, Ontario, Canada
Bone 44:137-44. 2009..The benefits of exercise are widely recognized, however physically active women can develop exercise associated menstrual cycle disturbances such as amenorrhea (i.e., estrogen deficiency) secondary to a chronic energy deficiency... - Relationships between vascular resistance and energy deficiency, nutritional status and oxidative stress in oestrogen deficient physically active womenEmma O'Donnell
Cardiovascular Regulation Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
Clin Endocrinol (Oxf) 70:294-302. 2009..We investigated whether other energy deficiency-associated factors might also be associated with altered cardiovascular function in these women... - Cognitive dietary restraint: impact on bone, menstrual and metabolic status in young womenJason D Vescovi
Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Sciences, University of Toronto, Toronto, ON, Canada M5S 2WS
Physiol Behav 95:48-55. 2008..A greater frequency of menstrual disturbances in women with higher CDR scores likely played a role in the reduced total body and lumbar spine BMD... - Beyond hypoestrogenism in amenorrheic athletes: energy deficiency as a contributing factor for bone lossMary Jane De Souza
Women's Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, 55 Harbord Street, Toronto, Ontario, M5S 2W6, Canada
Curr Sports Med Rep 4:38-44. 2005..These hormones (IGF-1 and leptin) play an important role in modulating bone turnover and bone mineral density in these women... - Short-term response of bone turnover to low-dose oral contraceptives in exercising women with hypothalamic amenorrheaJason D Vescovi
Women s Exercise and Bone Health Laboratory, Department of Exercise Science, University of Toronto, Toronto, ON, Canada
Contraception 77:97-104. 2008..We examined the response of bone turnover markers and indices of energy status after 2 weeks of oral contraceptive (OC) therapy in premenopausal women with exercise-associated menstrual disturbances (EAMD)... - Increased serum adiponectin concentrations in amenorrheic physically active women are associated with impaired bone health but not with estrogen exposureEmma O'Donnell
Cardiovascular Research Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada M5S 2W6
Bone 48:760-7. 2011..The role of adiponectin in mediating gonadal status and bone health in weight-stable healthy adult female athletes with secondary amenorrhea has not yet been described... - Long-term estrogen deficiency lowers regional blood flow, resting systolic blood pressure, and heart rate in exercising premenopausal womenPaula J Harvey
Women s Exercise and Bone Health Laboratory, Department of Medicine, University of Toronto, University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada
Am J Physiol Endocrinol Metab 292:E1401-9. 2007..These cardiovascular alterations represent markers of altered vascular function and autonomic regulation of which the long-term effects remain unknown... - The role of ovarian steroid hormones in moodDeborah H Schwartz
Department of Psychology, University of Toronto, Canada
Horm Behav 62:448-54. 2012..Thus, fluctuations in ovarian hormones do not contribute significantly to daily mood in healthy women... - Oligomenorrhoea in exercising women: a polycystic ovarian syndrome phenotype or distinct entity?Susan Awdishu
Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
Sports Med 39:1055-69. 2009..Further investigation is necessary to explore whether different endocrine aetiologies underly menstrual disturbances, particularly oligomenorrhoea, in physically active women... - The cardiovascular effects of chronic hypoestrogenism in amenorrhoeic athletes: a critical reviewMary Jane De Souza
Women's Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada
Sports Med 34:601-27. 2004..Future research should focus on the presentation and progression of these adverse cardiovascular parameters in physically active women and athletes with hypoestrogenism to determine their effects on long-term health... - Factors influencing exercise participation by older adults requiring chronic hemodialysis: a qualitative studyPia C Kontos
Toronto Rehabilitation Institute, 11035 550 University Ave, Toronto, ON, Canada, M5G 2A2
Int Urol Nephrol 39:1303-11. 2007..A shift is required in the culture of ESRD treatment programs towards a wellness perspective that includes expectations of exercise encouragement by the health care team and participation by patients... - Temperature regulation during rest and exercise in the cold in premenarcheal and menarcheal girlsPanagiota Klentrou
Faculty of Applied Health Sciences, Brock University, Ontario, Canada L2S 3A1
J Appl Physiol 96:1393-8. 2004.... - Heat acclimation and physical training adaptations of young women using different contraceptive hormonesLawrence E Armstrong
Human Performance Laboratory, Department of Kinesiology, University of Conneticut, Unit 1110, 2095 Hillside Road, Storrs, CT 06269-1110, USA
Am J Physiol Endocrinol Metab 288:E868-75. 2005.... - Serum creatine kinase activity varies with ovulatory status in regularly exercising, premenopausal womenHeather S Thompson
Molecular and Cellular Biology Program, University of Massachusetts, Amherst, Mass, USA
Horm Res 65:151-8. 2006..2 IU/l) subjects or the sedentary controls. CONCLUSIONS: These data demonstrate the complex association between ovarian hormone status and the normal serum CK response to regular mechanical stress imposed by chronic exercise training... - Female athlete triad errors and misunderstandingsNancy I Williams
Med Sci Sports Exerc 38:1021; author reply 1022. 2006 - Effects of lifetime exercise on the outcome of in vitro fertilizationAnne B Loucks
Obstet Gynecol 109:456-7. 2007 - Daily physical movement and bone mineral density among a mixed racial cohort of womenLinda S Pescatello
Center of Health Promotion, University of Connecticut, School of Allied Health, 358 Mansfield Road, U 2101, Storrs, CT 06269 2101, USA
Med Sci Sports Exerc 34:1966-70. 2002..We examined the influence of physical activities typical of everyday life on BMD among 151 women (52.0 +/- 0.9 yr). These women were of low socioeconomic status, and 57.6% were Hispanic, 17.2% black, and 24.5% white...