L A Dawson

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Objective assessment of swallowing dysfunction and aspiration after radiation concurrent with chemotherapy for head-and-neck cancer
    Avraham Eisbruch
    Department of Radiation Oncology, University of Michigan Hospital, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 53:23-8. 2002
  2. ncbi request reprint The role of radiotherapy in the treatment of liver metastases
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Cancer J 10:139-44. 2004
  3. ncbi request reprint Feasibility of a novel deformable image registration technique to facilitate classification, targeting, and monitoring of tumor and normal tissue
    Kristy K Brock
    Radiation Medicine Program, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 64:1245-54. 2006
  4. doi request reprint Three-dimensional motion of liver tumors using cine-magnetic resonance imaging
    Anna Kirilova
    Department of Radiation Physics, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 71:1189-95. 2008
  5. doi request reprint Adapting population liver motion models for individualized online image-guided therapy
    Thao Nguyen Nguyen
    Department of Medical Biophysics, University of Toronto, Ontario, Canada
    Conf Proc IEEE Eng Med Biol Soc 2008:3945-8. 2008
  6. pmc Comparison of simple and complex liver intensity modulated radiotherapy
    Mark T Lee
    Radiation Medicine Program, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Radiat Oncol 5:115. 2010
  7. ncbi request reprint Conformal chemoradiation for primary and metastatic liver malignancies
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario
    Semin Surg Oncol 21:249-55. 2003
  8. ncbi request reprint Hepatic arterial yttrium 90 microspheres: another treatment option for hepatocellular carcinoma
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada
    J Vasc Interv Radiol 16:161-4. 2005
  9. ncbi request reprint Use of principal component analysis to evaluate the partial organ tolerance of normal tissues to radiation
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 62:829-37. 2005
  10. ncbi request reprint Accuracy of daily image guidance for hypofractionated liver radiotherapy with active breathing control
    Laura A Dawson
    Department of Radiation Oncology, University of Toronto, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada
    Int J Radiat Oncol Biol Phys 62:1247-52. 2005

Detail Information

Publications67

  1. ncbi request reprint Objective assessment of swallowing dysfunction and aspiration after radiation concurrent with chemotherapy for head-and-neck cancer
    Avraham Eisbruch
    Department of Radiation Oncology, University of Michigan Hospital, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 53:23-8. 2002
    ..To objectively assess swallowing function after an intensive chemoradiation regimen for locally advanced head-and-neck cancer and to assess the clinical implications of swallowing dysfunction...
  2. ncbi request reprint The role of radiotherapy in the treatment of liver metastases
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Cancer J 10:139-44. 2004
    ....
  3. ncbi request reprint Feasibility of a novel deformable image registration technique to facilitate classification, targeting, and monitoring of tumor and normal tissue
    Kristy K Brock
    Radiation Medicine Program, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 64:1245-54. 2006
    ..To investigate the feasibility of a biomechanical-based deformable image registration technique for the integration of multimodality imaging, image guided treatment, and response monitoring...
  4. doi request reprint Three-dimensional motion of liver tumors using cine-magnetic resonance imaging
    Anna Kirilova
    Department of Radiation Physics, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 71:1189-95. 2008
    ..To measure the three-dimensional motion of liver tumors using cine-magnetic resonance imaging (MRI) and compare it to the liver motion assessed using fluoroscopy...
  5. doi request reprint Adapting population liver motion models for individualized online image-guided therapy
    Thao Nguyen Nguyen
    Department of Medical Biophysics, University of Toronto, Ontario, Canada
    Conf Proc IEEE Eng Med Biol Soc 2008:3945-8. 2008
    ..13 +/- 0.04 cm in the SI and AP directions, respectively. This technique was developed to complement and quickly adapt a full 3D biomechanical based deformable registration technique, MORFEUS, to be applied in the online setting...
  6. pmc Comparison of simple and complex liver intensity modulated radiotherapy
    Mark T Lee
    Radiation Medicine Program, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Radiat Oncol 5:115. 2010
    ..This study assesses whether target coverage and normal tissue avoidance can be maintained in liver cancer intensity-modulated radiotherapy (IMRT) plans by systematically reducing the complexity of the delivered fluence...
  7. ncbi request reprint Conformal chemoradiation for primary and metastatic liver malignancies
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario
    Semin Surg Oncol 21:249-55. 2003
    ....
  8. ncbi request reprint Hepatic arterial yttrium 90 microspheres: another treatment option for hepatocellular carcinoma
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada
    J Vasc Interv Radiol 16:161-4. 2005
  9. ncbi request reprint Use of principal component analysis to evaluate the partial organ tolerance of normal tissues to radiation
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 62:829-37. 2005
    ..The independent features of cDVHs that describe the largest variance are then investigated regarding complication risk...
  10. ncbi request reprint Accuracy of daily image guidance for hypofractionated liver radiotherapy with active breathing control
    Laura A Dawson
    Department of Radiation Oncology, University of Toronto, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada
    Int J Radiat Oncol Biol Phys 62:1247-52. 2005
    ..We report the accuracy of setup in the first 20 patients consecutively treated using this approach...
  11. ncbi request reprint Individualized image guided iso-NTCP based liver cancer SBRT
    Laura A Dawson
    Radiation Medicine Program, Princess Margaret Hospital, Canada
    Acta Oncol 45:856-64. 2006
    ..5 mm); however inter-fraction reproducibility (sigma) was worse (3.4 mm). Image guidance reduced the residual systematic and random setup errors significantly...
  12. doi request reprint Hepatocellular carcinoma: radiation therapy
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
    Cancer J 14:111-6. 2008
    ..Given the vascular properties of HCC, there is rationale for investigating RT with anti-vascular endothelial growth factor-targeted agents...
  13. ncbi request reprint Partial volume tolerance of the liver to radiation
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Semin Radiat Oncol 15:279-83. 2005
    ..The mean liver doses associated with a 5% risk of classic RILD for primary and metastatic liver cancer are 28 Gy and 32 Gy, respectively, in 2 Gy per fraction...
  14. doi request reprint The evolving role of radiation therapy in hepatocellular carcinoma
    L A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada
    Cancer Radiother 12:96-101. 2008
    ..Given the vascular properties of HCC, the combination of RT with anti-VEGF targeted agents may improve outcomes further...
  15. ncbi request reprint Image-guided radiotherapy: rationale, benefits, and limitations
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9
    Lancet Oncol 7:848-58. 2006
    ....
  16. doi request reprint Overview: Where does radiation therapy fit in the spectrum of liver cancer local-regional therapies?
    Laura A Dawson
    Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Semin Radiat Oncol 21:241-6. 2011
    ..In these patients, the benefits of radiation therapy over systemic therapy or best supportive therapy should be established in randomized trials...
  17. ncbi request reprint Advances in image-guided radiation therapy
    Laura A Dawson
    Radiation Medicine Program, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
    J Clin Oncol 25:938-46. 2007
    ..By reducing the variability in delivered doses across a population of patients, IGRT should also improve interpretation of future clinical trials...
  18. pmc Imaging in radiation oncology: a perspective
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Oncologist 15:338-49. 2010
    ..This paper reviews the integration of imaging and radiation oncology, and discusses challenges and opportunities for improving the practice of radiation oncology with imaging...
  19. doi request reprint Radiation-associated kidney injury
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 76:S108-15. 2010
    ..The available predictive models are suboptimal and require validation. Mitigation of radiation nephropathy with angiotensin-converting enzyme inhibitors and other compounds has been shown in animal models and, more recently, in patients...
  20. pmc Adapting liver motion models using a navigator channel technique
    T N Nguyen
    Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 3E2, Canada
    Med Phys 36:1061-73. 2009
    ..This method has potential applications in online assessment of motion at the time of treatment to improve image-guided radiotherapy and monitoring of intrafraction motion...
  21. ncbi request reprint Phase II trial of high-dose conformal radiation therapy with concurrent hepatic artery floxuridine for unresectable intrahepatic malignancies
    Edgar Ben-Josef
    Department of Radiation Oncology, Division of Hematology Oncology, University of Michigan, UH B2C490, 1500 E Medical Center Dr, Ann Arbor, MI 48109 0010, USA
    J Clin Oncol 23:8739-47. 2005
    ..A phase II trial was conducted to determine if high-dose radiation with concurrent hepatic arterial floxuridine would improve survival in patients with unresectable intrahepatic malignancies...
  22. doi request reprint Interfraction and intrafraction changes in amplitude of breathing motion in stereotactic liver radiotherapy
    Robert B Case
    Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 77:918-25. 2010
    ..Interfraction and intrafraction changes in amplitude of liver motion were assessed in patients with liver cancer treated with kV cone beam computed tomography (CBCT)-guided stereotactic body radiation therapy (SBRT)...
  23. ncbi request reprint Alterations in normal liver doses due to organ motion
    Mihaela Rosu
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
    Int J Radiat Oncol Biol Phys 57:1472-9. 2003
    ....
  24. doi request reprint Conformal radiotherapy for hepatocellular carcinoma
    R V Tse
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario M5G 2M9, Canada
    Crit Rev Oncol Hematol 67:113-23. 2008
    ..There is a particular interest in combining RT with anti-VEGF-targeted agents for their independent activity in HCC as well as their radiation sensitization properties. Randomized trials of RT are warranted...
  25. doi request reprint Interfraction and respiratory organ motion during conformal radiotherapy in gastric cancer
    Barbara Wysocka
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 77:53-9. 2010
    ..To quantify the interfraction and breathing organ motion during adjuvant radiotherapy for gastric cancer and assess organ stability in different breathing states...
  26. doi request reprint Change in diffusion weighted MRI during liver cancer radiotherapy: preliminary observations
    Cynthia L Eccles
    Radiation Medicine Program, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario, Canada
    Acta Oncol 48:1034-43. 2009
    ..To determine the feasibility of using changes in apparent diffusion coefficients (ADC) as a potential surrogate for tumour control or normal tissue injury...
  27. ncbi request reprint Assessment of residual error in liver position using kV cone-beam computed tomography for liver cancer high-precision radiation therapy
    Maria A Hawkins
    Radiation Medicine Program, Princess Margaret Hospital, Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 66:610-9. 2006
    ..To evaluate the residual error in liver position using breath-hold kilovoltage (kV) cone-beam computed tomography (CT) following on-line orthogonal megavoltage (MV) image-guided breath-hold liver cancer conformal radiotherapy...
  28. doi request reprint Treatment planning study to determine potential benefit of intensity-modulated radiotherapy versus conformal radiotherapy for unresectable hepatic malignancies
    Cynthia L Eccles
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 72:582-8. 2008
    ..To compare intensity-modulated radiotherapy (IMRT) with conformal RT (CRT) for hypofractionated isotoxicity liver RT and explore dose escalation using IMRT for the same/improved nominal risk of liver toxicity in a treatment planning study...
  29. ncbi request reprint Prediction of radiation-induced liver disease by Lyman normal-tissue complication probability model in three-dimensional conformal radiation therapy for primary liver carcinoma: in regards to Xu et al. (Int J Radiat Oncol Biol Phys 2006;65:189-195)
    Randall K Ten Haken
    Int J Radiat Oncol Biol Phys 66:1272; author reply 1272-3. 2006
  30. doi request reprint Inter- and intrafraction variability in liver position in non-breath-hold stereotactic body radiotherapy
    Robert B Case
    Princess Margaret Hospital, Toronto, ON, Canada
    Int J Radiat Oncol Biol Phys 75:302-8. 2009
    ..The inter- and intrafraction variability of liver position was assessed in patients with liver cancer treated with kilovoltage cone-beam computed tomography (CBCT)-guided stereotactic body radiotherapy...
  31. doi request reprint Incorporating heterogeneity correction and 4DCT in lung stereotactic body radiation therapy (SBRT): The effect on target coverage, organ-at-risk doses, and dose conformity
    Kevin N Franks
    Princess Margaret Hospital, Toronto, Ontario, Canada
    Med Dosim 35:101-7. 2010
    ..Lower prescription doses may be required when prospectively planning with HC to achieve a similar level of toxicity and dose spillage as expected when planning based on homogeneous dose calculations...
  32. ncbi request reprint Radiation therapy for hepatocellular carcinoma: from palliation to cure
    Maria A Hawkins
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Cancer 106:1653-63. 2006
    ..3 months to 9.7 months. Although outcomes after high-dose conformal RT for liver-confined HCC were excellent, the potential survival benefit of RT should be tested in randomized controlled trials that require international collaboration...
  33. doi request reprint Phase I study of individualized stereotactic body radiotherapy for hepatocellular carcinoma and intrahepatic cholangiocarcinoma
    Regina V Tse
    Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    J Clin Oncol 26:657-64. 2008
    ..To report outcomes of a phase I study of individualized stereotactic body radiotherapy treatment (SBRT) for unresectable hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (IHC)...
  34. ncbi request reprint Prospective comparison of computed tomography and magnetic resonance imaging for liver cancer delineation using deformable image registration
    Jon Paul Voroney
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 66:780-91. 2006
    ..The aim of this study was to compare magnetic resonance imaging (MRI) with computed tomography (CT) for liver cancer tumor definition for high-precision radiotherapy planning...
  35. doi request reprint Phase I study of individualized stereotactic body radiotherapy of liver metastases
    Mark T Lee
    Radiation Medicine Program, Department of Biostatistics and Medical Oncology, Princess Margaret Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Clin Oncol 27:1585-91. 2009
    ..To report on the outcomes of a phase I study of stereotactic body radiotherapy (SBRT) for treatment of liver metastases...
  36. ncbi request reprint Daily targeting of intrahepatic tumors for radiotherapy
    James M Balter
    Department of Radiation Oncology, University of Michigan Health Systems, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 52:266-71. 2002
    ..This paper reports our initial experience treating 8 patients with focal liver tumors using this system...
  37. ncbi request reprint Evaluating the influence of setup uncertainties on treatment planning for focal liver tumors
    James M Balter
    Department of Radiation Oncology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA
    Int J Radiat Oncol Biol Phys 63:610-4. 2005
    ..This study evaluates the influence of population as well as patient-specific setup distributions on treatment plans for focal liver tumors...
  38. doi request reprint Image guidance in non-small cell lung cancer
    B C John Cho
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Semin Radiat Oncol 20:164-70. 2010
    ..Furthermore, functional imaging, although in its infancy, has the potential to significantly improve RT, from RT planning and delivery to outcome assessment...
  39. doi request reprint Quantifying interfraction and intrafraction tumor motion in lung stereotactic body radiotherapy using respiration-correlated cone beam computed tomography
    Jean Pierre Bissonnette
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 75:688-95. 2009
    ..However, the precise extent of these changes in breathing pattern is not well known. We evaluated the inter- and intrafractional changes in tumor motion amplitude (DeltaM) over an SBRT course...
  40. pmc Adaptive management of liver cancer radiotherapy
    Kristy K Brock
    Department of Radiation Oncology, Princess Margaret Hospital, University Health Network, University of Toronto, Toronto, ON, Canada
    Semin Radiat Oncol 20:107-15. 2010
    ..Patient selection, clinical workflow, and quality assurance must be considered and developed before integrating these techniques into clinical practice...
  41. ncbi request reprint Interventions to reduce organ motion effects in radiation delivery
    Laura A Dawson
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Ontario, Canada
    Semin Radiat Oncol 14:76-80. 2004
    ..Approaches to minimize nonrespiratory organ motion include maintaining the same preparative regimen before each treatment and ensuring comfortable immobilization and short overall treatment time...
  42. doi request reprint Radiotherapy as a bridge to liver transplantation for hepatocellular carcinoma
    Charbel Sandroussi
    Multiorgan Transplant Department, Toronto General Hospital, Toronto, ON, USA
    Transpl Int 23:299-306. 2010
    ..CRT is a safe and efficacious local bridging therapy for patients with advanced HCC who are on the waiting list for LT. Further studies are warranted to compare the effectiveness of CRT to other local treatment regimens for HCC...
  43. ncbi request reprint Reproducibility of liver position using active breathing coordinator for liver cancer radiotherapy
    Cynthia Eccles
    Radiation Medicine Program, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 64:751-9. 2006
    ....
  44. doi request reprint Improving image-guided target localization through deformable registration
    Kristy K Brock
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network and University of Toronto, Toronto, Ontario, Canada
    Acta Oncol 47:1279-85. 2008
    ..To quantify the improvements in online target localization using kV cone beam CT (CBCT) with deformable registration...
  45. doi request reprint The Canadian Association of Radiation Oncology scope of practice guidelines for lung, liver and spine stereotactic body radiotherapy
    A Sahgal
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 24:629-39. 2012
    ..The aim was to define the scope of practice guidelines for the profession to ensure safe practice specific for the most common sites of lung, liver and spine SBRT...
  46. doi request reprint Stereotactic radiation therapy and selective internal radiation therapy for hepatocellular carcinoma
    A Bujold
    Radiation Medicine Program, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario, Canada
    Cancer Radiother 15:54-63. 2011
    ..Most appropriate patient populations and when which type of radiation therapy should be best employed in the vast therapeutic armamentarium of hepatocellular carcinoma are still to be clarified...
  47. ncbi request reprint Accuracy of finite element model-based multi-organ deformable image registration
    K K Brock
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9
    Med Phys 32:1647-59. 2005
    ....
  48. ncbi request reprint Lack of influence of intravenous contrast on head and neck IMRT dose distributions
    Daniel Letourneau
    Radiation Medicine Program, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Acta Oncol 47:90-4. 2008
    ..Here, the effect of physiologic and non-physiologic extremes of i.v. contrast densities on intensity modulated radiotherapy (IMRT) plans for patients with head and neck cancer was investigated...
  49. ncbi request reprint Upper abdominal malignancies: intensity-modulated radiation therapy
    Mojgan Taremi
    Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Canada
    Front Radiat Ther Oncol 40:272-88. 2007
    ..Clinical experience with dose-escalated IMRT is limited, and IMRT should continue to be studied in clinical trials before it is routinely used for upper abdominal malignancies...
  50. ncbi request reprint Cancer of the gallbladder and extrahepatic bile ducts
    Sean P Cleary
    Department of Surgery, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada
    Curr Probl Surg 44:396-482. 2007
  51. doi request reprint Radiotherapy for hepatocellular carcinoma: an overview
    Sunil Krishnan
    Division of Radiation Oncology, M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 097, Houston, Texas 77030, United States
    Ann Surg Oncol 15:1015-24. 2008
  52. ncbi request reprint Phase I study of involved-field radiotherapy preceding autologous stem cell transplantation for patients with high-risk lymphoma or Hodgkin's disease
    Laura A Dawson
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA
    Int J Radiat Oncol Biol Phys 59:208-18. 2004
    ....
  53. ncbi request reprint Salivary gland sparing and improved target irradiation by conformal and intensity modulated irradiation of head and neck cancer
    Avraham Eisbruch
    Department of Radiation Oncology, University of Michigan, 1500 Medical Center Drive, Ann Arbor, Michigan 48109, USA
    World J Surg 27:832-7. 2003
    ..The pattern of recurrence suggests that careful escalation of the dose to areas judged to be at highest risk may improve tumor control...
  54. doi request reprint Cone-beam CT assessment of interfraction and intrafraction setup error of two head-and-neck cancer thermoplastic masks
    Michael Velec
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 76:949-55. 2010
    ..To prospectively compare setup error in standard thermoplastic masks and skin-sparing masks (SSMs) modified with low neck cutouts for head-and-neck intensity-modulated radiation therapy (IMRT) patients...
  55. ncbi request reprint Assessment of a model-based deformable image registration approach for radiation therapy planning
    Michael R Kaus
    Philips Radiation Oncology Systems, Fitchburg, WI 53705, USA
    Int J Radiat Oncol Biol Phys 68:572-80. 2007
    ....
  56. ncbi request reprint Analysis of radiation-induced liver disease using the Lyman NTCP model
    Laura A Dawson
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 53:810-21. 2002
    ..To describe the dose-volume tolerance for radiation-induced liver disease (RILD) using the Lyman-Kutcher-Burman (LKB) normal tissue complication probability (NTCP) model...
  57. ncbi request reprint Predictive factors of local-regional recurrences following parotid sparing intensity modulated or 3D conformal radiotherapy for head and neck cancer
    Mary Feng
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
    Radiother Oncol 77:32-8. 2005
    ..Predictive factors for local-regional (LR) failures after parotid-sparing, Intensity modulated (IMRT) or 3D conformal radiotherapy for head and neck (HN) cancers were assessed...
  58. ncbi request reprint Recurrences near base of skull after IMRT for head-and-neck cancer: implications for target delineation in high neck and for parotid gland sparing
    Avraham Eisbruch
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 59:28-42. 2004
    ..Locoregional (LR) failures near the base of the skull, and their relationships to the targets in the high neck, were examined in a series of patients who underwent intensity-modulated radiotherapy (IMRT) for head-and-neck cancer...
  59. ncbi request reprint Case 23-2005: a man with a mass in the liver
    Maria A Hawkins
    N Engl J Med 353:2195-7; author reply 2195-7. 2005
  60. doi request reprint MR imaging correlates of intratumoral tissue types within colorectal liver metastases: a high-spatial-resolution fresh ex vivo radiologic-pathologic correlation study
    Laurent Milot
    Joint Department of Medical Imaging and Department of Radiation Oncology, Princess Margaret Hospital, Department of Pathology, and Division of General Surgery, University Health Network and Mount Sinai Hospital, University of Toronto, 610 University Ave, Toronto, ON, Canada M5G 2M9
    Radiology 254:747-54. 2010
    ..This SI pattern is unusual for common benign liver lesions and may be helpful in the MR imaging diagnosis of colorectal liver metastases. (c) RSNA, 2010...
  61. ncbi request reprint Prospective comparison of breast pain in patients participating in a randomized trial of breast-conserving surgery and tamoxifen with or without radiotherapy
    Gamal Rayan
    Department of Radiation Oncology, Princess Margaret Hospital University Health Network and University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 55:154-61. 2003
    ..To determine whether breast pain affects quality of life (QOL) after breast-conserving surgery and tamoxifen (TAM) with or without adjuvant breast radiotherapy (RT)...
  62. doi request reprint Emerging role of radiotherapy in the management of liver metastases
    Anand Swaminath
    From the Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Cancer J 16:150-5. 2010
    ..Finally, randomized trials of RT for liver metastases are needed to better define the benefits of RT for these patients...
  63. ncbi request reprint Daily prostate targeting using implanted radiopaque markers
    Dale Litzenberg
    Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, MI 48103 0010, USA
    Int J Radiat Oncol Biol Phys 52:699-703. 2002
    ..A system has been implemented for daily localization of the prostate through radiographic localization of implanted markers. This report summarizes an initial trial to establish the accuracy of patient setup via this system...
  64. ncbi request reprint Acceleration of hyperfractionated chemoradiation regimen for advanced head and neck cancer
    Aaron M Allen
    Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA
    Head Neck 29:137-42. 2007
    ..Our aim was to evaluate the acceleration of a hyperfractionated, concurrent chemoradiation regimen (HxCRT) for advanced head and neck squamous cell carcinoma (HNSCC)...
  65. ncbi request reprint Quality of life after parotid-sparing IMRT for head-and-neck cancer: a prospective longitudinal study
    Alexander Lin
    Department of Radiation Oncology, Hospital of the University of Michigan, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 57:61-70. 2003
    ..To assess potential improvements in broader aspects of quality of life (QOL), we initiated a study of patient-reported QOL and its predictors after IMRT...
  66. doi request reprint Radiation recall dermatitis triggered by multi-targeted tyrosine kinase inhibitors: sunitinib and sorafenib
    Caroline Chung
    Princess Margaret Hospital, Toronto, Ontario, Canada
    Anticancer Drugs 21:206-9. 2010
    ..The clinical presentations of these two cases were consistent with one hypothesized mechanism of radiation recall, an idiosyncratic drug hypersensitivity reaction...
  67. ncbi request reprint Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109 0010, USA
    J Clin Oncol 24:2437-43. 2006
    ..We compared the outcome of breast-conserving surgery and radiotherapy in BRCA1/2 mutation carriers with breast cancer versus that of matched sporadic controls...