Denise Daley

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. pmc Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study
    Denise Daley
    Department of Epidemiology and Biostatistics, University Hospitals of Cleveland Case Western Reserve University, Cleveland, OH 44106, USA
    Am J Hum Genet 82:723-36. 2008
  2. pmc Path: a tool to facilitate pathway-based genetic association analysis
    David Zamar
    James Hogg iCAPTURE Center, University of British Columbia UBC, Vancouver, BC, Canada
    Bioinformatics 25:2444-6. 2009
  3. pmc Asthma and genes encoding components of the vitamin D pathway
    Yohan Bosse
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Canada
    Respir Res 10:98. 2009
  4. ncbi request reprint Approaches to the study of inflammatory gene haplotypes and susceptibility to cardiac, vascular and pulmonary diseases
    Denise Daley
    The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, University of British Columbia, St Paul s Hospital, 1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada
    Curr Opin Mol Ther 7:226-33. 2005
  5. ncbi request reprint Is TGFBR1*6A a susceptibility allele for nonsyndromic familial colorectal neoplasia?
    Denise Daley
    Department of Epidemiology, University Hospitals of Cleveland Case Western Reserve University and Howard Hughes Medical Institute, and Cleveland, Ohio, USA
    Cancer Epidemiol Biomarkers Prev 16:892-4. 2007
  6. doi request reprint Analyses of associations with asthma in four asthma population samples from Canada and Australia
    Denise Daley
    James Hogg iCAPTURE Center, University of British Columbia UBC, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
    Hum Genet 125:445-59. 2009
  7. pmc Non-Hodgkin lymphoma risk and variants in genes controlling lymphocyte development
    Johanna M Schuetz
    Canada s Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada
    PLoS ONE 8:e75170. 2013
  8. doi request reprint Associations and interactions of genetic polymorphisms in innate immunity genes with early viral infections and susceptibility to asthma and asthma-related phenotypes
    Denise Daley
    University of British Columbia James Hogg Research Centre, Institute for Heart and Lung Health, Vancouver, British Columbia, Canada
    J Allergy Clin Immunol 130:1284-93. 2012
  9. pmc A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2
    Georgia L Wiesner
    Department of Genetics, Center for Human Genetics, Ireland Comprehensive Cancer Center, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH 44106, USA
    Proc Natl Acad Sci U S A 100:12961-5. 2003
  10. pmc Lack of association of TIM3 polymorphisms and allergic phenotypes
    Jian Zhang
    James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, St, Paul s Hospital, Vancouver, BC, Canada
    BMC Med Genet 10:62. 2009

Collaborators

Detail Information

Publications25

  1. pmc Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study
    Denise Daley
    Department of Epidemiology and Biostatistics, University Hospitals of Cleveland Case Western Reserve University, Cleveland, OH 44106, USA
    Am J Hum Genet 82:723-36. 2008
    ..3 at marker D17S1308 in the breast/colon subgroup identified HIC1 as a candidate gene. We demonstrated that using clinical information, unaffected siblings, and family history can increase the analytical power of a linkage study...
  2. pmc Path: a tool to facilitate pathway-based genetic association analysis
    David Zamar
    James Hogg iCAPTURE Center, University of British Columbia UBC, Vancouver, BC, Canada
    Bioinformatics 25:2444-6. 2009
    ....
  3. pmc Asthma and genes encoding components of the vitamin D pathway
    Yohan Bosse
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Canada
    Respir Res 10:98. 2009
    ..Genetic variants at the vitamin D receptor (VDR) locus are associated with asthma and atopy. We hypothesized that polymorphisms in other genes of the vitamin D pathway are associated with asthma or atopy...
  4. ncbi request reprint Approaches to the study of inflammatory gene haplotypes and susceptibility to cardiac, vascular and pulmonary diseases
    Denise Daley
    The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, University of British Columbia, St Paul s Hospital, 1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada
    Curr Opin Mol Ther 7:226-33. 2005
    ..Applied and methodological fields are discussed and examples of how haplotypes are used to study complex diseases in this modern era are provided...
  5. ncbi request reprint Is TGFBR1*6A a susceptibility allele for nonsyndromic familial colorectal neoplasia?
    Denise Daley
    Department of Epidemiology, University Hospitals of Cleveland Case Western Reserve University and Howard Hughes Medical Institute, and Cleveland, Ohio, USA
    Cancer Epidemiol Biomarkers Prev 16:892-4. 2007
    ..We conclude that there remains an unidentified susceptibility locus in the region 9q22.2-31.2...
  6. doi request reprint Analyses of associations with asthma in four asthma population samples from Canada and Australia
    Denise Daley
    James Hogg iCAPTURE Center, University of British Columbia UBC, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
    Hum Genet 125:445-59. 2009
    ..To aid in future replication studies of asthma genes a comprehensive database was compiled and is available to the scientific community at http://genapha.icapture.ubc.ca/...
  7. pmc Non-Hodgkin lymphoma risk and variants in genes controlling lymphocyte development
    Johanna M Schuetz
    Canada s Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada
    PLoS ONE 8:e75170. 2013
    ..It is likely that moderate sample size, inter-subtype and other genetic heterogeneity, and small true effect sizes account for the lack of replicable findings. ..
  8. doi request reprint Associations and interactions of genetic polymorphisms in innate immunity genes with early viral infections and susceptibility to asthma and asthma-related phenotypes
    Denise Daley
    University of British Columbia James Hogg Research Centre, Institute for Heart and Lung Health, Vancouver, British Columbia, Canada
    J Allergy Clin Immunol 130:1284-93. 2012
    ..The innate immune system is essential for host survival because of its ability to recognize invading pathogens and mount defensive responses...
  9. pmc A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2
    Georgia L Wiesner
    Department of Genetics, Center for Human Genetics, Ireland Comprehensive Cancer Center, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH 44106, USA
    Proc Natl Acad Sci U S A 100:12961-5. 2003
    ..2-31.2 in a pattern consistent with autosomal dominant disease alleles. These data suggest that a single locus can contribute to disease susceptibility in a subset of patients with nonsyndromic forms of familial colorectal neoplasia...
  10. pmc Lack of association of TIM3 polymorphisms and allergic phenotypes
    Jian Zhang
    James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, St, Paul s Hospital, Vancouver, BC, Canada
    BMC Med Genet 10:62. 2009
    ..The aims of this study were to examine whether genetic variation in the promoter region of TIM3 influenced transcription of the gene and risk for allergic phenotypes...
  11. ncbi request reprint A thymic stromal lymphopoietin gene variant is associated with asthma and airway hyperresponsiveness
    Jian Qing He
    James Hogg Imaging, Cell Analysis, and Phenotyping Toward Understanding Responsive, Reparative, Remodelling, and Recombinant Events iCAPTURE Centre, University of British Columbia, Vancouver, British Columbia, Canada
    J Allergy Clin Immunol 124:222-9. 2009
    ..Association of genetic variation in thymic stromal lymphopoietin with IgE levels has been reported for human subjects...
  12. pmc Genetic variation in cell death genes and risk of non-Hodgkin lymphoma
    Johanna M Schuetz
    Canada s Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada
    PLoS ONE 7:e31560. 2012
    ..Poor control of cell death in lymphocytes can lead to autoimmune disease or cancer, making genes involved in programmed cell death of lymphocytes logical candidate genes for lymphoma susceptibility...
  13. pmc SLIMS--a user-friendly sample operations and inventory management system for genotyping labs
    Thea Van Rossum
    James Hogg iCAPTURE Center, University of British Columbia UBC, Vancouver, BC, Canada V6Z1Y6
    Bioinformatics 26:1808-10. 2010
    ..SLIMS gives labs a feasible alternative that is easily accessible, user-centrically designed and feature-rich. To facilitate system customization, and utilization for other groups, manuals have been written for users and developers...
  14. doi request reprint BRISK--research-oriented storage kit for biology-related data
    Alan Tan
    James Hogg iCAPTURE Center, Department of Medicine, University of British Columbia, Vancouver, BC, Canada V6Z1Y6
    Bioinformatics 27:2422-5. 2011
    ..Inefficient methods of data transfer and access control still plague research collaboration. As science becomes more and more collaborative in nature, the need for a system that adequately manages data sharing becomes paramount...
  15. doi request reprint Functional genetic variation in NFKBIA and susceptibility to childhood asthma, bronchiolitis, and bronchopulmonary dysplasia
    Salman Ali
    Department of Pediatrics, British Columbia Children s Hospital and Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia V6H 3V4, Canada
    J Immunol 190:3949-58. 2013
    ....
  16. doi request reprint The identification of colon cancer susceptibility genes by using genome-wide scans
    Denise Daley
    Department of Medicine, St Paul s Hospital, University of British Columbia, Vancouver, BC, Canada
    Methods Mol Biol 653:3-21. 2010
    ..Study design considerations, methodology, and the execution of linkage and genome-wide association studies that use both family and case-control designs are covered in this chapter...
  17. pmc Interaction of gender and body mass index (BMI) reveals evidence of linkage for hypertension in the Framingham Heart Study
    Denise Daley
    Department of Epidemiology and Biostatistics, Rammelkamp Center for Education and Research, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio, USA
    BMC Genet 4:S45. 2003
    ..Incorporation of covariates, in particular the interaction between two independent risk factors (gender and BMI) greatly improved our ability to detect linkage...
  18. pmc The relationship between telomere length and mortality in chronic obstructive pulmonary disease (COPD)
    Jee Lee
    The Providence Heart and Lung Institute at St Paul s Hospital, The UBC James Hogg Research Centre and Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 7:e35567. 2012
    ..In conclusion, COPD patients have short leukocyte telomeres, which are in turn associated increased risk of total and cancer mortality. Accelerated aging is of particular relevance to cancer mortality in COPD...
  19. doi request reprint TLR5 as an anti-inflammatory target and modifier gene in cystic fibrosis
    Christoph J Blohmke
    Department of Paediatrics, BC Children s Hospital and Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    J Immunol 185:7731-8. 2010
    ....
  20. doi request reprint Rare and common variants in the Apolipoprotein E gene in healthy oldest old
    Lauren C Tindale
    Canada s Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada
    Neurobiol Aging 35:727.e1-3. 2014
    ..Our findings were consistent with ε4 being a risk factor for early mortality...
  21. pmc Cost-effective prediction of gender-labeling errors and estimation of gender-labeling error rates in candidate-gene association studies
    Conghui Qu
    Department of Statistics and Actuarial Science, Simon Fraser University Burnaby, BC, Canada
    Front Genet 2:31. 2011
    ..We also show how the predictions can be used in a two-phase sampling design to estimate the gender-labeling error rates for an entire study, at a fraction of the cost of a conventional design...
  22. pmc A comparison of five methods for selecting tagging single-nucleotide polymorphisms
    Kelly M Burkett
    The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, University of British Columbia, St Paul s Hospital, Vancouver, BC V6Z 146, Canada
    BMC Genet 6:S71. 2005
    ..Finally, when compared to the haplotypic methods, the reference method performed as well or worse in the region with ancestral disease haplotype structure...
  23. ncbi request reprint Association of urokinase-type plasminogen activator with asthma and atopy
    Philippe Bégin
    University of Montreal Community Genomic Medicine Centre, Chicoutimi University Hospital, Saguenay, Quebec, Canada
    Am J Respir Crit Care Med 175:1109-16. 2007
    ..This region has demonstrated evidence for linkage in a genome scan for asthma in a sample from northeastern Quebec. Here, we hypothesized that uPA may function as a regulator of asthma susceptibility...
  24. ncbi request reprint Effects of covariates: a summary of Group 5 contributions
    Elizabeth R Hauser
    Section of Medical Genetics, Department of Medicine, Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Genet Epidemiol 25:S43-9. 2003
    ..Finally, the results of Group 5 studies show that inclusion of covariates can increase the power to detect genes for complex traits, and has the potential to advance an understanding of the role of genes in these complex traits...
  25. doi request reprint Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues
    Karine Tremblay
    Hopital Laval, Universite Laval, Quebec, Canada
    J Allergy Clin Immunol 122:529-36.e17. 2008
    ..Eight genes in the immune signaling pathway shown to be differentially expressed in asthmatic lung biopsy specimens in a previous microarray experiment were selected as candidate genes for asthma susceptibility...