N J Coupland
Affiliation: University of Alberta
- Increased sympathetic response to standing in panic disorderNick J Coupland
Psychopharmacology Unit, School of Medical Sciences, University Walk, Bristol, UK
Psychiatry Res 118:69-79. 2003..These findings are consistent with recent evidence for increased sympathetic baroreflex function in PD and may be relevant to the pathophysiology of the disorder...
- Flumazenil challenge in social phobiaN J Coupland
Psychopharmacology Unit, University of Bristol, School of Medical Sciences, United Kingdom
Depress Anxiety 11:27-30. 2000..Situational fears that are provoked by social cues therefore do not predict panic responses to flumazenil...
- Positive and negative affect differentially influence identification of facial emotionsNicholas J Coupland
Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada
Depress Anxiety 19:31-4. 2004..25; P=.022). Even within a normal range of mood, mood predicted emotion identification, supporting constructs of positive and negative affect derived originally from self-report measures...
- Social phobia: etiology, neurobiology, and treatmentN J Coupland
Department of Psychiatry, University of Alberta, Edmonton, Canada
J Clin Psychiatry 62:25-35. 2001..Neuroimaging techniques are at the early stage of identifying abnormalities at the neurotransmitter and systems levels...
- Response to pentagastrin after acute phenylalanine and tyrosine depletion in healthy men: a pilot studyN Coupland
Department of Psychiatry, University of Alberta, 1E7 13 Walter Mackenzie Centre, 8440 112 St, Edmonton AB T6G 2B7
J Psychiatry Neurosci 26:247-51. 2001..To assess the effects of the acute depletion of the catecholamine precursors phenylalanine and tyrosine on mood and pentagastrin-induced anxiety...
- Effects of diazepam on facial emotion recognitionNick J Coupland
Psychopharmacology Research Unit, Department of Psychiatry, University of Alberta, Edmonton
J Psychiatry Neurosci 28:452-63. 2003..The hypothesis was that, in comparison with placebo, diazepam would impair the recognition of facial anger in healthy volunteers, but not the recognition of 5 other basic emotions: happiness, surprise, fear, sadness and disgust...
- Increased beclomethasone-induced vasoconstriction in women with posttraumatic stress disorderNick J Coupland
1E7 16 WMC, Psychopharmacology Research Unit, Department of Psychiatry, University of Alberta, 8440 112 Street, Edmonton, T6G 2B7, Alberta, Canada
J Psychiatr Res 37:221-8. 2003..Preliminary evidence has been found for increased peripheral glucocorticoid sensitivity in PTSD. Further study is required to replicate this finding and assess its relationship to the pathophysiology of the disorder...
- Beclomethasone-induced vasoconstriction in women with major depressive disorderNick J Coupland
Department of Psychiatry, University of Alberta Hospital, Edmonton, AB
J Psychiatry Neurosci 28:364-9. 2003..The objective was to test the hypothesis that BIV would be reduced in unmedicated women with MDD compared with healthy controls...
- Response to flumazenil in women with premenstrual dysphoric disorderJ M Le Melledo
Clinical Investigation Unit, Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada
Am J Psychiatry 157:821-3. 2000..The authors sought to determine whether the administration of flumazenil would induce marked panic symptoms in women suffering from premenstrual dysphoric disorder...
- Use of selective serotonin reuptake inhibitors and other serotonergic drugs in the biological dissection of affective disordersD J Nutt
Psychopharmacology Unit, School of Medical Sciences, Bristol, UK
Int Clin Psychopharmacol 9:53-9. 1995..This may provide a greater understanding of the mechanisms of serotonin dysregulation in affective disorders, and may ultimately improve treatment of these conditions...
- Sleep changes during long-term treatment of depression with fluvoxamine--a home-based studyS J Wilson
Psychopharmacology Unit, School of Medical Sciences, University of Bristol, UK
Psychopharmacology (Berl) 149:360-5. 2000..The growing trend towards outpatient and community care has highlighted the need for studies of sleep in depression in a more naturalistic setting, and during longer periods of treatment in line with recommended clinical practice...
- Default mode network connectivity as a predictor of post-traumatic stress disorder symptom severity in acutely traumatized subjectsR A Lanius
Department of Psychiatry, The University of Western Ontario, London, ON, Canada
Acta Psychiatr Scand 121:33-40. 2010..The goal of this study was to investigate the relationship between default mode network connectivity and the severity of post-traumatic stress disorder (PTSD) symptoms in a sample of eleven acutely traumatized subjects...
- The role of beta-endorphin in the pathophysiology of major depressionK M Hegadoren
Faculty of Nursing, University of Alberta, Edmonton, AB, Canada T6G 2G3
Neuropeptides 43:341-53. 2009....
- In vivo quantification of hippocampal subfields using 4.7 T fast spin echo imagingN V Malykhin
Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
Neuroimage 49:1224-30. 2010....
- Cognitive distortions in an acutely traumatized sample: an investigation of predictive power and neural correlatesJ K Daniels
Department of Psychiatry, The University of Western Ontario, University Hospital, London, Ontario, Canada
Psychol Med 41:2149-57. 2011..Previous studies have shown that cognitive distortions in the early aftermath of traumatic events can predict future PTSD severity but, to date, no studies have investigated the neural correlates of this association...
- A rapid high-pressure liquid chromatographic procedure for determination of flumazenil in plasmaL Zedkova
Department of Psychiatry, Psychopharmacology Research Unit and Neurochemical Research Unit, University of Alberta, Edmonton, AB, Canada
J Pharmacol Toxicol Methods 46:57-60. 2001..A rapid high-pressure liquid chromatographic (HPLC) method was developed for determination of flumazenil in plasma samples from PD patients receiving flumazenil and the results obtained with that assay are reported here...
- Posttraumatic stress disorder Part III: health effects of interpersonal violence among womenK M Hegadoren
University of Alberta, Edmonton, Alberta, Canada
Perspect Psychiatr Care 42:163-73. 2006....