Elena Maria Comelli

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Multifaceted transcriptional regulation of the murine intestinal mucus layer by endogenous microbiota
    Elena M Comelli
    Department of Nutrition and Health, Nestle Research Center, 1000 Lausanne 26, Switzerland
    Genomics 91:70-7. 2008
  2. doi request reprint Biomarkers of human gastrointestinal tract regions
    Elena Maria Comelli
    Department of Nutrition and Health, Nestle Research Center, Vers chez les Blanc, Lausanne, Switzerland
    Mamm Genome 20:516-27. 2009
  3. ncbi request reprint Neonatal antibiotic treatment alters gastrointestinal tract developmental gene expression and intestinal barrier transcriptome
    Alexandra Schumann
    Department of Nutrition and Health, Nestle Research Center, Vers chez les Blanc, Lausanne, Switzerland
    Physiol Genomics 23:235-45. 2005
  4. ncbi request reprint A focused microarray approach to functional glycomics: transcriptional regulation of the glycome
    Elena M Comelli
    Department of Molecular Biology and Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA
    Glycobiology 16:117-31. 2006
  5. ncbi request reprint Activation of murine CD4+ and CD8+ T lymphocytes leads to dramatic remodeling of N-linked glycans
    Elena M Comelli
    Departments of Molecular Biology and Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Immunol 177:2431-40. 2006
  6. ncbi request reprint Topographical variation in metabolic signatures of human gastrointestinal biopsies revealed by high-resolution magic-angle spinning 1H NMR spectroscopy
    Yulan Wang
    Department of Biomolecular Medicine, SORA Division, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, United Kingdom
    J Proteome Res 6:3944-51. 2007

Collaborators

  • Christine Cherbut
  • Magali Faure
  • Yulan Wang
  • Alexandra Schumann
  • Irène E Corthésy-Theulaz
  • Mattias J Rantalainen
  • John C Lindon
  • Jeremy K Nicholson
  • Grigorios Fotopoulos
  • Sunil Kochhar
  • Laurent B Fay
  • Elaine Holmes
  • Huiru Tang
  • Gian Dorta
  • Robert Mansourian
  • Irene Corthesy-Theulaz
  • Sophie Nutten
  • Dominique Donnicola
  • Clara Garcia-Rodenas

Detail Information

Publications6

  1. ncbi request reprint Multifaceted transcriptional regulation of the murine intestinal mucus layer by endogenous microbiota
    Elena M Comelli
    Department of Nutrition and Health, Nestle Research Center, 1000 Lausanne 26, Switzerland
    Genomics 91:70-7. 2008
    ..These findings show that a well-established microbial community participates in the regulation of the gut mucus layer and that its composition and adequacy to the host are key factors in this process...
  2. doi request reprint Biomarkers of human gastrointestinal tract regions
    Elena Maria Comelli
    Department of Nutrition and Health, Nestle Research Center, Vers chez les Blanc, Lausanne, Switzerland
    Mamm Genome 20:516-27. 2009
    ..Furthermore, the approach implemented here, and validated by retrieving known gene profiles, allowed the identification of promising new leads in both healthy and disease states...
  3. ncbi request reprint Neonatal antibiotic treatment alters gastrointestinal tract developmental gene expression and intestinal barrier transcriptome
    Alexandra Schumann
    Department of Nutrition and Health, Nestle Research Center, Vers chez les Blanc, Lausanne, Switzerland
    Physiol Genomics 23:235-45. 2005
    ..These results suggest that early treatment with a large-spectrum antibiotic deeply affects the gut barrier function at the suckling-weaning interface, a period during which the gut is challenged by an array of novel food-borne antigens...
  4. ncbi request reprint A focused microarray approach to functional glycomics: transcriptional regulation of the glycome
    Elena M Comelli
    Department of Molecular Biology and Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA
    Glycobiology 16:117-31. 2006
    ..The glycogene chip reported in this study is available to the scientific community through the Consortium for Functional Glycomics (CFG) (http://www.functionalglycomics.org)...
  5. ncbi request reprint Activation of murine CD4+ and CD8+ T lymphocytes leads to dramatic remodeling of N-linked glycans
    Elena M Comelli
    Departments of Molecular Biology and Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Immunol 177:2431-40. 2006
    ..The results have implications for differential recognition of activated and unactivated T cells by dendritic cells and B cells expressing glycan-binding proteins that recognize terminal sequences of N-linked glycans...
  6. ncbi request reprint Topographical variation in metabolic signatures of human gastrointestinal biopsies revealed by high-resolution magic-angle spinning 1H NMR spectroscopy
    Yulan Wang
    Department of Biomolecular Medicine, SORA Division, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, United Kingdom
    J Proteome Res 6:3944-51. 2007
    ..This work indicates that 1H HRMAS NMR studies may be of value in analyzing local metabolic variation due to pathological processes in gut biopsies...