Sean P Cleary

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk
    Sean P Cleary
    Cancer Care Ontario, Toronto, Ontario, Canada
    Am J Epidemiol 172:1000-14. 2010
  2. ncbi Prognosis and results after resection of very large (>or=10 cm) hepatocellular carcinoma
    Shimul A Shah
    Department of Surgery, Multi Organ Transplantation Unit, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Canada
    J Gastrointest Surg 11:589-95. 2007
  3. ncbi Germline MYH mutations in a clinic-based series of Canadian multiple colorectal adenoma patients
    Marina E Croitoru
    Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    J Surg Oncol 95:499-506. 2007
  4. ncbi Missense polymorphisms in the adenomatous polyposis coli gene and colorectal cancer risk
    Sean P Cleary
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Dis Colon Rectum 51:1467-73; discussion 1473-4. 2008
  5. ncbi Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study
    Sean P Cleary
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    Gastroenterology 136:1251-60. 2009
  6. ncbi Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk
    Marina E Croitoru
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
    J Natl Cancer Inst 96:1631-4. 2004
  7. ncbi Predictors of peri-opertative morbidity and liver dysfunction after hepatic resection in patients with chronic liver disease
    Elisa Greco
    Department of Surgery, University Health Network, University of Toronto, Toronto, Canada
    HPB (Oxford) 13:559-65. 2011
  8. ncbi An analysis of resection vs transplantation for early hepatocellular carcinoma: defining the optimal therapy at a single institution
    Shimul A Shah
    Department of Surgery, University Health Network, University of Toronto, Toronto, Canada
    Ann Surg Oncol 14:2608-14. 2007
  9. ncbi Surgery for gallbladder cancer: a population-based analysis
    Natalie G Coburn
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    J Am Coll Surg 207:371-82. 2008
  10. ncbi Clinical and economic comparison of laparoscopic to open liver resections using a 2-to-1 matched pair analysis: an institutional experience
    Faizal D Bhojani
    Division of General Surgery, University Health Network, 200 Elizabeth Street, Toronto, Ontario, Canada
    J Am Coll Surg 214:184-95. 2012

Collaborators

Detail Information

Publications17

  1. ncbi Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk
    Sean P Cleary
    Cancer Care Ontario, Toronto, Ontario, Canada
    Am J Epidemiol 172:1000-14. 2010
    ..03) status. These findings support the hypothesis that prolonged cigarette smoking is associated with increased risk of colorectal cancer and that this risk may be modified by variation in carcinogen metabolism genes...
  2. ncbi Prognosis and results after resection of very large (>or=10 cm) hepatocellular carcinoma
    Shimul A Shah
    Department of Surgery, Multi Organ Transplantation Unit, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Canada
    J Gastrointest Surg 11:589-95. 2007
    ..Few potentially curative treatment options exist besides resection for patients with very large (>or=10 cm) hepatocellular carcinoma (HCC). We sought to examine the outcomes and risk factors for recurrence after resection of >or=10 cm HCC...
  3. ncbi Germline MYH mutations in a clinic-based series of Canadian multiple colorectal adenoma patients
    Marina E Croitoru
    Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    J Surg Oncol 95:499-506. 2007
    ..Our objective was to determine the significance of MYH mutations in a series of Canadian patients with multiple adenomas...
  4. ncbi Missense polymorphisms in the adenomatous polyposis coli gene and colorectal cancer risk
    Sean P Cleary
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Dis Colon Rectum 51:1467-73; discussion 1473-4. 2008
    ..Whereas truncating germline mutations of the adenomatous polyposis coli (APC) gene give rise to familial adenomatous polyposis, missense polymorphisms of APC may confer a weaker risk for colorectal cancer...
  5. ncbi Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study
    Sean P Cleary
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    Gastroenterology 136:1251-60. 2009
    ..The objective of this study was to determine colorectal cancer (CRC) risk associated with mutations in the MYH gene...
  6. ncbi Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk
    Marina E Croitoru
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
    J Natl Cancer Inst 96:1631-4. 2004
    ..These two MYH gene mutations may account for a substantial fraction of hereditary colorectal cancer...
  7. ncbi Predictors of peri-opertative morbidity and liver dysfunction after hepatic resection in patients with chronic liver disease
    Elisa Greco
    Department of Surgery, University Health Network, University of Toronto, Toronto, Canada
    HPB (Oxford) 13:559-65. 2011
    ..There is no universal risk stratification scheme for CLD patients undergoing resection...
  8. ncbi An analysis of resection vs transplantation for early hepatocellular carcinoma: defining the optimal therapy at a single institution
    Shimul A Shah
    Department of Surgery, University Health Network, University of Toronto, Toronto, Canada
    Ann Surg Oncol 14:2608-14. 2007
    ....
  9. ncbi Surgery for gallbladder cancer: a population-based analysis
    Natalie G Coburn
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    J Am Coll Surg 207:371-82. 2008
    ..Single institutional studies report an aggressive surgical approach improves survival. This analysis was performed to examine the components of surgical resection and resultant survival...
  10. ncbi Clinical and economic comparison of laparoscopic to open liver resections using a 2-to-1 matched pair analysis: an institutional experience
    Faizal D Bhojani
    Division of General Surgery, University Health Network, 200 Elizabeth Street, Toronto, Ontario, Canada
    J Am Coll Surg 214:184-95. 2012
    ..Our center has introduced a laparoscopic liver resection (LLR) program over the past 3 years. Our objective is to describe the initial clinical experience with LLR, including a detailed cost analysis...
  11. ncbi Genetic variants in carcinogen-metabolizing enzymes, cigarette smoking and pancreatic cancer risk
    Ji Hyun Jang
    Population Studies and Surveillance, Cancer Care Ontario, 620 University Avenue, Toronto, Ontario, Canada M5G 2L7
    Carcinogenesis 33:818-27. 2012
    ..04) and smoking status and N-acetyltransferase 2-857 (P = 0.03). Variants of carcinogen metabolism genes are independently associated with pancreatic cancer risk and may modify the risk posed by smoking...
  12. ncbi Neuroendocrine tumors of the gastrointestinal tract: a decade of experience at the Princess Margaret Hospital
    Jeff Rothenstein
    Department of Medical Oncology and Hematology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Am J Clin Oncol 31:64-70. 2008
    ..Over the past decade, novel treatment approaches have been developed. The purpose of this study was to review the experience at the Princess Margaret Hospital in treating patients with NET over the past decade...
  13. ncbi Recurrence after liver resection for hepatocellular carcinoma: risk factors, treatment, and outcomes
    Shimul A Shah
    Department of Surgery, Toronto General Hospital, University of Toronto, Toronto, Canada
    Surgery 141:330-9. 2007
    ..The purpose of this study was to identify risk factors for the recurrence of HCC and to examine long-term outcomes after resection...
  14. ncbi Heterozygosity for the BLM(Ash) mutation and cancer risk
    Sean P Cleary
    Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Cancer Res 63:1769-71. 2003
    ....
  15. ncbi Cancer of the gallbladder and extrahepatic bile ducts
    Sean P Cleary
    Department of Surgery, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada
    Curr Probl Surg 44:396-482. 2007
  16. ncbi Association of hepatic hemangiomatosis with giant cavernous hemangioma in the adult population: prevalence, imaging appearance, and relevance
    Kartik S Jhaveri
    Department of Medical Imaging, University of Toronto, University Health Network and Mount Sinai Hospital, 610 University Ave, 3 957, Toronto, ON M5G2M9, Canada
    AJR Am J Roentgenol 196:809-15. 2011
    ..The purpose of our study was to evaluate the association of hepatic hemangiomatosis with giant cavernous hemangioma (GCH) and describe the imaging appearances and clinical relevance...
  17. ncbi Prognostic factors in resected pancreatic adenocarcinoma: analysis of actual 5-year survivors
    Sean P Cleary
    Department of Surgery, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada M5G 2X5
    J Am Coll Surg 198:722-31. 2004
    ..These and other similar data should provide further stimulus for the development and evaluation of novel screening strategies to improve early detection of this disease...