Clanachan A. Contribution of protons to post-ischemic Na(+) and Ca(2+) overload and left ventricular mechanical dysfunction. J Cardiovasc Electrophysiol. 2006;17 Suppl 1:S141-S148 pubmed
Masoud W, Abo Al Rob O, Yang Y, Lopaschuk G, Clanachan A. Tolerance to ischaemic injury in remodelled mouse hearts: less ischaemic glycogenolysis and preserved metabolic efficiency. Cardiovasc Res. 2015;107:499-508 pubmed publisher
..Less glycogen utilization in CAL hearts during ischaemia may contribute to increased ischaemic tolerance by limiting ischaemic proton production that may improve ion homeostasis during early reperfusion. ..
Soraya H, Masoud W, Gandhi M, Garjani A, Clanachan A. Myocardial mechanical dysfunction following endotoxemia: role of changes in energy substrate metabolism. Basic Res Cardiol. 2016;111:24 pubmed publisher
..The beneficial repartitioning of glucose metabolism in reperfused endotoxemic hearts may contribute to the cardioprotected phenotype. ..
Zaugg M, Lou P, Lucchinetti E, Gandhi M, Clanachan A. Postconditioning with Intralipid emulsion protects against reperfusion injury in post-infarct remodeled rat hearts by activation of ROS-Akt/Erk signaling. Transl Res. 2017;186:36-51.e2 pubmed publisher
..Our data provide a rationale for the clinical evaluation of ILE postconditioning where ILE is administered as a bolus at the onset of reperfusion. ..