Elena Choleris

Summary

Affiliation: University of Guelph
Country: Canada

Publications

  1. pmc An estrogen-dependent four-gene micronet regulating social recognition: a study with oxytocin and estrogen receptor-alpha and -beta knockout mice
    Elena Choleris
    Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 100:6192-7. 2003
  2. ncbi request reprint Estrogen receptor beta agonists in neurobehavioral investigations
    Elena Choleris
    University of Guelph, Department of Psychology, MacKinnon Building, Guelph, Ontario, N1G 2W1, Canada
    Curr Opin Investig Drugs 9:760-73. 2008
  3. ncbi request reprint Acute corticosterone sexually dimorphically facilitates social learning and inhibits feeding in mice
    Elena Choleris
    Department of Psychology and Neuroscience Program, University of Guelph, Guelph, ON, Canada Electronic address
    Neuropharmacology 75:191-200. 2013
  4. doi request reprint Estrogenic involvement in social learning, social recognition and pathogen avoidance
    Elena Choleris
    Department of Psychology, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Front Neuroendocrinol 33:140-59. 2012
  5. pmc Differential effects of dopamine receptor D1-type and D2-type antagonists and phase of the estrous cycle on social learning of food preferences, feeding, and social interactions in mice
    Elena Choleris
    Department of Psychology, University of Guelph, Guelph, ON, Canada
    Neuropsychopharmacology 36:1689-702. 2011
  6. doi request reprint Neuroendocrinology of social information processing in rats and mice
    Elena Choleris
    Department of Psychology, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Front Neuroendocrinol 30:442-59. 2009
  7. pmc Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice
    Elena Choleris
    Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 104:4670-5. 2007
  8. ncbi request reprint Involvement of estrogen receptor alpha, beta and oxytocin in social discrimination: A detailed behavioral analysis with knockout female mice
    E Choleris
    Department of Psychology, University of Guelph, Guelph, Ontario, Canada
    Genes Brain Behav 5:528-39. 2006
  9. ncbi request reprint Functional genomics of social recognition
    E Choleris
    Department of Psychology, University of Guelph, Guelph, ON, Canada
    J Neuroendocrinol 16:383-9. 2004
  10. ncbi request reprint Steroidal/neuropeptide interactions in hypothalamus and amygdala related to social anxiety
    Elena Choleris
    Department of Psychology, University of Guelph, Guelph, ON, Canada
    Prog Brain Res 170:291-303. 2008

Collaborators

Detail Information

Publications39

  1. pmc An estrogen-dependent four-gene micronet regulating social recognition: a study with oxytocin and estrogen receptor-alpha and -beta knockout mice
    Elena Choleris
    Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 100:6192-7. 2003
    ..The proper operation of a social recognition mechanism allows for the expression of appropriate social behaviors, aggressive or affiliative...
  2. ncbi request reprint Estrogen receptor beta agonists in neurobehavioral investigations
    Elena Choleris
    University of Guelph, Department of Psychology, MacKinnon Building, Guelph, Ontario, N1G 2W1, Canada
    Curr Opin Investig Drugs 9:760-73. 2008
    ..The development of highly selective, commercially available ERbeta-specific antagonists would greatly benefit preclinical and applied research...
  3. ncbi request reprint Acute corticosterone sexually dimorphically facilitates social learning and inhibits feeding in mice
    Elena Choleris
    Department of Psychology and Neuroscience Program, University of Guelph, Guelph, ON, Canada Electronic address
    Neuropharmacology 75:191-200. 2013
    ..These results indicate that CORT facilitates social learning, like social recognition. Hence, CORT may generally increase social information processing. ..
  4. doi request reprint Estrogenic involvement in social learning, social recognition and pathogen avoidance
    Elena Choleris
    Department of Psychology, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Front Neuroendocrinol 33:140-59. 2012
    ....
  5. pmc Differential effects of dopamine receptor D1-type and D2-type antagonists and phase of the estrous cycle on social learning of food preferences, feeding, and social interactions in mice
    Elena Choleris
    Department of Psychology, University of Guelph, Guelph, ON, Canada
    Neuropsychopharmacology 36:1689-702. 2011
    ..Overall, these results suggest a differential involvement of the D1-type and D2-type receptors in the regulation of social learning, feeding, and agonistic behaviors that are likely mediated by different underlying states...
  6. doi request reprint Neuroendocrinology of social information processing in rats and mice
    Elena Choleris
    Department of Psychology, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Front Neuroendocrinol 30:442-59. 2009
    ..Thus, androgens and estrogens control social information processing by regulating OT and AVP. This control is finely tuned for different forms of social information processing...
  7. pmc Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice
    Elena Choleris
    Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 104:4670-5. 2007
    ..Understanding the functional genomics of OT and OTR in social recognition should help elucidate the neurobiological bases of human disorders of social behavior (e.g., autism)...
  8. ncbi request reprint Involvement of estrogen receptor alpha, beta and oxytocin in social discrimination: A detailed behavioral analysis with knockout female mice
    E Choleris
    Department of Psychology, University of Guelph, Guelph, Ontario, Canada
    Genes Brain Behav 5:528-39. 2006
    ..Therefore, the OT, ER-alpha, and ER-beta genes are necessary, to different degrees, for social discrimination and, thus, for the modulation of social behavior (e.g. aggression, affiliation)...
  9. ncbi request reprint Functional genomics of social recognition
    E Choleris
    Department of Psychology, University of Guelph, Guelph, ON, Canada
    J Neuroendocrinol 16:383-9. 2004
    ..This model forms the core around which increasingly complex genetic, hormonal and neural interactions associated with social behaviours and recognition can be organized...
  10. ncbi request reprint Steroidal/neuropeptide interactions in hypothalamus and amygdala related to social anxiety
    Elena Choleris
    Department of Psychology, University of Guelph, Guelph, ON, Canada
    Prog Brain Res 170:291-303. 2008
    ..In humans, such increased social anxiety might account for some features of autism...
  11. ncbi request reprint Differential effects of estrogen receptor alpha and beta specific agonists on social learning of food preferences in female mice
    Amy E Clipperton
    Department of Psychology, University of Guelph, Guelph, ON, Canada
    Neuropsychopharmacology 33:2362-75. 2008
    ..This suggests that the estrous cycle's effects on social learning may be due to the action of ERbeta on Submissive Behavior, or to ERbeta countering that of ERalpha...
  12. pmc Oxytocin, vasopressin and estrogen receptor gene expression in relation to social recognition in female mice
    Amy E Clipperton-Allen
    Department of Psychology, University of Guelph, 50 Stone Road East, Guelph, Ontario, Canada, N1G 2W1
    Physiol Behav 105:915-24. 2012
    ..Finally, increased lateral amygdala gene activation in the LR mice may be associated with general learning impairments, while decreased lateral amygdala activity may indicate more efficient cognitive mechanisms in the HR mice...
  13. ncbi request reprint Genes, odours and the recognition of parasitized individuals by rodents
    Martin Kavaliers
    Department of Psychology, Social Sciences Centre, University of Western Ontario, London, Ontario, Canada, N6A 5C2
    Trends Parasitol 21:423-9. 2005
    ..In this article, we provide a framework ("micronet") by which the genetic, hormonal and neural interactions associated with social behaviours and recognition and avoidance of parasitized individuals can be explored...
  14. pmc Low doses of 17β-estradiol rapidly improve learning and increase hippocampal dendritic spines
    Anna Phan
    Department of Psychology, University of Guelph, Guelph, Ontario, Canada
    Neuropsychopharmacology 37:2299-309. 2012
    ..These effects may be mediated by the rapid formation of new dendritic spines in the hippocampus...
  15. ncbi request reprint Recognition and avoidance of the odors of parasitized conspecifics and predators: differential genomic correlates
    Martin Kavaliers
    Department of Psychology, University of Western Ontario, London, Ont, Canada
    Neurosci Biobehav Rev 29:1347-59. 2005
    ..These findings reveal some of the mechanisms associated with the olfactory mediated recognition of parasitized individuals and predators...
  16. ncbi request reprint Interplay of oxytocin, vasopressin, and sex hormones in the regulation of social recognition
    Christopher S Gabor
    Department of Psychology and Neuroscience Program, University of Guelph, Ontario, Canada
    Behav Neurosci 126:97-109. 2012
    ..g., social bonds, social hierarchies) in a sex specific manner. This points at an important role for these neuroendocrine systems in the regulation of the sex differences that are evident in social behavior and of sociality as a whole...
  17. doi request reprint Effects of an estrogen receptor alpha agonist on agonistic behaviour in intact and gonadectomized male and female mice
    Amy E Clipperton-Allen
    Department of Psychology, University of Guelph, 50 Stone Rd East, Guelph, ON, Canada N1G 2W1
    Psychoneuroendocrinology 36:981-95. 2011
    ..This suggests that, as in social recognition, ERα may be necessary for the activation of agonistic responses, while ERβ may play a modulatory role...
  18. ncbi request reprint Oxytocin and estrogen receptor alpha and beta knockout mice provide discriminably different odor cues in behavioral assays
    M Kavaliers
    Department of Psychology, University of Western Ontario, London, Canada
    Genes Brain Behav 3:189-95. 2004
    ..Therefore, in behavioral assays one causal route by which gene inactivation alters the social behavior of knockout mice may be mediated through the partners'modified responses to their odors...
  19. doi request reprint Male risk taking, female odors, and the role of estrogen receptors
    Martin Kavaliers
    Dept of Psychology, University of Western Ontario, London, Ontario, Canada
    Physiol Behav 107:751-61. 2012
    ..The implications and relations of these findings with rodents to ERs and the regulation of human risk taking are briefly considered...
  20. ncbi request reprint Olfactory-mediated parasite recognition and avoidance: linking genes to behavior
    Martin Kavaliers
    Department of Psychology, Social Science Center, University of Western Ontario, London, ON, Canada N6A 5C2
    Horm Behav 46:272-83. 2004
    ..These findings reveal some of the genes involved in the mediation of social recognition in the ecologically relevant context of parasite recognition and avoidance...
  21. doi request reprint Sociality, pathogen avoidance, and the neuropeptides oxytocin and arginine vasopressin
    Martin Kavaliers
    Department of Psychology, Social Science Centre, University of Western Ontario, London, Ontario, Canada N6A 5C1
    Psychol Sci 22:1367-74. 2011
    ..The evidence reviewed here suggests that OT and AVP likely play parallel roles in modulating the recognition and avoidance of socially relevant pathogen threat in both humans and rodents...
  22. ncbi request reprint Genetic influences on aggressive behaviors and arousability in animals
    Sonoko Ogawa
    Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, New York 10021, USA
    Ann N Y Acad Sci 1036:257-66. 2004
    ..Normal performance of this micronet is required for social recognition and thus for control over aggression. Underlying certain genetic influences on sociosexual behaviors and aggression may be alterations in generalized brain arousal...
  23. doi request reprint Rapid effects of estrogen receptor α and β selective agonists on learning and dendritic spines in female mice
    Anna Phan
    Department of Psychology, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Endocrinology 152:1492-502. 2011
    ..To our knowledge, this is the first report of estrogens' effects on learning within such a short time frame...
  24. doi request reprint Mechanisms underlying an ability to behave ethically
    Donald W Pfaff
    Laboratory of Neurobiology and Behavior, Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Am J Bioeth 8:10-9. 2008
    ..That balance results not only from genetic influences on temperament but also from environmental effects particularly during critical neonatal and pubertal periods...
  25. ncbi request reprint Genes for sex hormone receptors controlling mouse aggression
    Donald Pfaff
    Laboratory of Neurobiology and Behaviour, The Rockefeller University, 1230 York A venue, New York, NY 10021, USA
    Novartis Found Symp 268:78-89; discussion 89-95, 96-9. 2005
    ..7) Some genetic influences on aggression derive from their effects on fundamental, generalized arousal of the mammalian brain, which underlies the expression of any emotional behaviour...
  26. pmc Agonistic behavior in males and females: effects of an estrogen receptor beta agonist in gonadectomized and gonadally intact mice
    Amy E Clipperton Allen
    Department of Psychology, University of Guelph, Guelph, ON, Canada
    Psychoneuroendocrinology 35:1008-22. 2010
    ..This non-attack aggression in females is increased by acute activation of ERbeta. Thus, acute activation of ERbeta similarly mediates agonistic behavior in adult male and female CD-1 mice...
  27. ncbi request reprint Impaired discrimination of and aversion to parasitized male odors by female oxytocin knockout mice
    M Kavaliers
    Department of Psychology and Neuroscience Program, University of Western Ontario, London, Ontario, Canada
    Genes Brain Behav 2:220-30. 2003
    ..These findings indicate that a normal OT gene comprises an essential part of the central recognition mechanism whereby females can both reduce the transmission of parasites to themselves and select for parasite-free males...
  28. pmc Luman/CREB3 recruitment factor regulates glucocorticoid receptor activity and is essential for prolactin-mediated maternal instinct
    Amanda C Martyn
    Departments of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada
    Mol Cell Biol 32:5140-50. 2012
    ..We thus postulate that LRF plays a critical role in the attenuation of the HPA axis through repression of glucocorticoid stress signaling during parturition and the postpartum period...
  29. doi request reprint Enhancing effect of heroin on social recognition learning in male Sprague-Dawley rats: modulation by heroin pre-exposure
    Annemarie Levy
    Department of Psychology, University of Guelph, Guelph, Ontario, Canada
    Psychopharmacology (Berl) 204:413-21. 2009
    ..There is evidence that pre-exposure to drugs of abuse can induce sensitization to several of their effects...
  30. ncbi request reprint Decreased cADPR and increased NAD+ in the Cd38-/- mouse
    Genevieve S Young
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ont, Canada N1G 3W1
    Biochem Biophys Res Commun 346:188-92. 2006
    ..We also report significant increases in brain, lung, and kidney NAD(+) in the Cd38(-/-) mouse, and provide the first experimental demonstration of the proximate relationship between CD38 and NAD(+)...
  31. ncbi request reprint A detailed ethological analysis of the mouse open field test: effects of diazepam, chlordiazepoxide and an extremely low frequency pulsed magnetic field
    E Choleris
    Room 9222D, Department of Psychology, Social Science Center, University of Western Ontario, London, Ontario, Canada N6A 5C2
    Neurosci Biobehav Rev 25:235-60. 2001
    ..e. pulsed magnetic field) on anxiety-like behaviors, but also permits the examination of non-specific effects, in particular those on general activity...
  32. pmc Estradiol differentially regulates lipocalin-type prostaglandin D synthase transcript levels in the rodent brain: Evidence from high-density oligonucleotide arrays and in situ hybridization
    Jessica A Mong
    Laboratory of Neurobiology and Behavior, The Rockefeller University, 1230 York Ave, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 100:318-23. 2003
    ....
  33. ncbi request reprint Use of salient and non-salient visuospatial cues by rats in the Morris Water Maze
    Genevieve S Young
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
    Physiol Behav 87:794-9. 2006
    ..This suggests that during place learning in Long-Evans rats, non-salient visual cues may play a dominant role, at least when salient cue presentation is limited to four cues...
  34. ncbi request reprint Antipredator responses and defensive behavior: ecological and ethological approaches for the neurosciences
    M Kavaliers
    Department of Psychology, University of Western Ontario, N6A 5C2, London, Ont, Canada
    Neurosci Biobehav Rev 25:577-86. 2001
    ..The utility of these approaches and their relevance to the design and interpretation of various neuroscience studies is addressed here...
  35. ncbi request reprint Parasites and behaviour: an ethopharmacological perspective
    M Kavaliers
    Department of Psychology, Social Sciences Centre, University of Western Ontario, London, Ontario, Canada
    Parasitol Today 16:464-8. 2000
    ..host defences, mate responses) and their neurobiological correlates. Martin Kavaliers, Douglas Colwell and Elena Choleris explain here how ethopharmacology can be used to address the mechanisms that underlie the often subtle effects ..
  36. ncbi request reprint Analgesic responses of male mice exposed to the odors of parasitized females: effects of male sexual experience and infection status
    M Kavaliers
    Department of Psychology, University of Western Ontario, London, Canada
    Behav Neurosci 112:1001-11. 1998
    ..These results show that male mice can discriminate between the odors of parasitized and nonparasitized females and find the odors of parasitized estrous females aversive...
  37. pmc Inadvertent social information and the avoidance of parasitized male mice: a role for oxytocin
    Martin Kavaliers
    Department of Psychology and Statistical and Actuarial Sciences, University of Western Ontario, London, ON, Canada N6A 5C2
    Proc Natl Acad Sci U S A 103:4293-8. 2006
    ..These findings suggest that OT genes are necessary for the processing of inadvertent social information and likely the integration of both direct and indirect social information...
  38. doi request reprint Estrogen receptors alpha and beta mediate different aspects of the facilitatory effects of female cues on male risk taking
    Martin Kavaliers
    Department Psychology, University of Western Ontario, London, Ontario, Canada N6A 5C2
    Psychoneuroendocrinology 33:634-42. 2008
    ....
  39. ncbi request reprint Effects of magnetic field exposure on open field behaviour and nociceptive responses in mice
    Cristina Del Seppia
    Institute of Clinical Physiology, CNR, Via Moruzzi 1, 56124 Pisa, Italy
    Behav Brain Res 144:1-9. 2003
    ..These results suggest that exposure to altered magnetic fields induce a more rapid habituation to a novel environment...