Sarah J Childs

Summary

Affiliation: University of Calgary
Country: Canada

Publications

  1. Bahrami N, Childs S. Pericyte Biology in Zebrafish. Adv Exp Med Biol. 2018;1109:33-51 pubmed publisher
    ..Going forward, these models may be key contributors in elucidating the role of vascular mural cells in regulating vessel diameter and hence, blood flow. ..
  2. Goi M, Childs S. Patterning mechanisms of the sub-intestinal venous plexus in zebrafish. Dev Biol. 2016;409:114-128 pubmed publisher
    ..However Vegf promotes sprouting of the predominantly venous plexus and Bmp promotes outgrowth of the structure. We propose that the SIVP is a unique model to understand novel mechanisms utilized in organ-specific angiogenesis. ..
  3. Lamont R, Wu C, Ryu J, Vu W, Davari P, Sobering R, et al. The LIM-homeodomain transcription factor Islet2a promotes angioblast migration. Dev Biol. 2016;414:181-92 pubmed publisher
    ..Thus Isl2a may act as an intermediate between Notch signaling and genetic programs controlling angioblast number and migration, placing it as a novel transcriptional regulator of early angiogenesis. ..
  4. Jiang X, Sarsons C, Gomez Garcia M, Cramb D, Rinker K, Childs S. Quantum dot interactions and flow effects in angiogenic zebrafish (Danio rerio) vessels and human endothelial cells. Nanomedicine. 2017;13:999-1010 pubmed publisher
    ..In vivo, flow arrest after nanoparticle injection still results in venous accumulation at 18 h. Overall our results suggest that both QD charge and blood flow modulate particle-endothelial cell interactions. ..

Collaborators