Research Topics
Species | Nilesh ChandeSummaryAffiliation: University of Western Ontario Country: Canada Publications
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Detail Information
Publications
Collagenous colitis and lymphocytic colitis: patient characteristics and clinical presentationNilesh Chande
Department of Medicine, University of Western Ontario and St Joseph s Health Centre, London, Ontario, Canada
Scand J Gastroenterol 40:343-7. 2005....- Yo Jyo Hen Shi Ko (YHK) improves transaminases in nonalcoholic steatohepatitis (NASH): a randomized pilot studyNilesh Chande
Division of Gastroenterology, The University of Western Ontario, Ontario, Canada
Dig Dis Sci 51:1183-9. 2006..YHK is well tolerated. Further studies are justified to assess the impact of YHK in the natural history of NASH... - Microscopic colitis associated with lansoprazole: report of two cases and a review of the literatureNilesh Chande
Department of Medicine, Division of Gastroenterology, University of Western Ontario and London Health Sciences Centre, South St Hospital, 375 South Street, London, Ontario Canada
Scand J Gastroenterol 42:530-3. 2007..Clinicians must be aware of this association when prescribing this medication; when a patient taking lansoprazole develops diarrhea, substituting an alternative proton-pump inhibitor should allow resolution of the diarrhea... 
Microscopic colitis: an approach to treatmentNilesh Chande
Division of Gastroenterology, The University of Western Ontario, London Health Sciences Centre South Street Hospital, London, Ontario
Can J Gastroenterol 22:686-8. 2008..Rarely, patients require surgery for refractory disease. An evidence-based and practical approach to treatment should optimize the treatment response while minimizing potential adverse events...- A survey of Canadian gastroenterologists about the use of methotrexate in patients with Crohn's diseaseNilesh Chande
Division of Gastroenterology, University of Western Ontario, London Health Sciences Centre, Canada
Can J Gastroenterol 19:553-8. 2005..Still, there are no guidelines for monitoring patients with CD on MTX, and physicians must decide based on rheumatological literature about how to monitor their patients... 
Interventions for treating microscopic colitis: a Cochrane Inflammatory Bowel Disease and Functional Bowel Disorders Review Group systematic review of randomized trialsNilesh Chande
Division of Gastroenterology, London Health Sciences Centre, The University of Western Ontario, South Street Hospital, 375 South St, London, Ontario, Canada
Am J Gastroenterol 104:235-41; quiz 234, 242. 2009..To conduct a systematic review to determine effective treatments for patients with collagenous colitis or lymphocytic colitis, the two subtypes of microscopic colitis...- Microscopic colitis: an updateVikram Tangri
Department of Medicine, The University of Western Ontario, Canada
J Clin Gastroenterol 43:293-6. 2009..Recently there has been more research on the pathophysiology of MC, and studies on treatment have demonstrated budesonide to be most effective, although other treatments also hold promise... - Interventions for treating collagenous colitis: a Cochrane Inflammatory Bowel Disease Group systematic review of randomized trialsNilesh Chande
Division of Gastroenterology, London Health Sciences Centre, London, Ontario N6A 5A5, Canada
Am J Gastroenterol 99:2459-65. 2004..The evidence for benefit with bismuth subsalicylate or prednisolone is weaker. It is not clear that any of these agents produce actual remission, as opposed to clinical and histological improvement of the disease... - The safety and tolerability of methotrexate for treating patients with Crohn's diseaseNilesh Chande
Division of Gastroenterology, The University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada
J Clin Gastroenterol 45:599-601. 2011..To determine the safety and tolerance of methotrexate for treating patients with Crohn's disease in clinical practice... - Use of budesonide in the treatment of microscopic colitisVikram Tangri
Department of Medicine, The University of Western Ontario and London Health Sciences Centre, London, Ontario, Canada
Saudi J Gastroenterol 16:236-8. 2010..This drug improves quality of life in patients while causing few mild adverse events. Budesonide is an effective treatment of microscopic colitis that is safe and well tolerated... - Wait times for diagnostic colonoscopy among outpatients with colorectal cancer: a comparison with Canadian Association of Gastroenterology targetsMichael Sai Lai Sey
Department of Medicine, Division of Gastroenterology, University of Western Ontario, London
Can J Gastroenterol 26:894-6. 2012..However, specific wait times for colonoscopy among patients diagnosed with colorectal cancer remain unknown... - Sleep disruption secondary to overnight call shifts is associated with irritable bowel syndrome in residents: a cross-sectional studyMalcolm M Wells
Department of Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
Am J Gastroenterol 107:1151-6. 2012..Sleep disruption has been associated with irritable bowel syndrome (IBS). We hypothesized that residents with greater sleep disruption secondary to intermittent overnight call shifts would have a higher prevalence of IBS... - The human proton-coupled folate transporter (hPCFT): modulation of intestinal expression and function by drugsBradley L Urquhart
Division of Clinical Pharmacology, Department of Medicine, University of Western Ontario, London Health Sciences Centre Univ Campus, 339 Windermere Rd, London, Ontario, Canada
Am J Physiol Gastrointest Liver Physiol 298:G248-54. 2010..Importantly, we note that PPI drug use appears to be associated with reduced hPCFT expression in vivo... - Unfractionated or low molecular weight heparin for induction of remission in ulcerative colitis: a Cochrane inflammatory bowel disease and functional bowel disorders systematic review of randomized trialsNilesh Chande
Gastroenterology, University of Western Ontario, London, Ontario, Canada
Inflamm Bowel Dis 17:1979-86. 2011..We aimed to systematically review the efficacy of unfractionated heparin (UFH) or low molecular weight heparins (LMWH) for remission induction in patients with ulcerative colitis (UC)... - Nonutility of routine testing of stool for ova and parasites in a tertiary care Canadian centreMahmoud Mosli
London Health Sciences Centre, Department of Medicine, London, ON N6A 5W9, Canada
Can J Microbiol 58:653-9. 2012..The purpose of this study was to examine the diagnostic yield of routine stool testing for O&P in a Canadian tertiary care centre and to estimate the potential clinical benefit of a positive result... - A cross-sectional study of the association between overnight call and irritable bowel syndrome in medical studentsMalcolm Wells
Department of Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario N6A 5W9, Canada
Can J Gastroenterol 26:281-4. 2012..Overnight call shifts also lead to a disruption of the endogenous circadian rhythm... - Percutaneous endoscopic gastrostomy tube placement for end-stage palliation of malignant gastrointestinal obstructionsAnouar Teriaky
Division of Gastroenterology, Department of Medicine, The University of Western Ontario and London Health Sciences Centre, London, Ontario, Canada
Saudi J Gastroenterol 18:95-8. 2012..The purpose of this study is to determine the efficacy of venting PEG tubes in relieving nausea and vomiting and assessing complications associated with tube placement... - Outcomes of a 5-year follow-up of patients with sessile serrated adenomasAnouar Teriaky
Department of Medicine, The University of Western Ontario and London Health Sciences Centre, London, Ontario, Canada
Scand J Gastroenterol 47:178-83. 2012..Sessile serrated adenomas (SSAs) are precursors to colorectal cancer (CRC). The purpose of this study is to determine the occurrence of new polyps and CRC in patients with an SSA over a 5-year follow-up interval... - Predictors of disease severity in ulcerative colitis patients from Southwestern OntarioLee S Roth
Division of Gastroenterology, London Health Sciences Centre, Victoria Hospital, 800 Commissioner s Road East, London, Ontario, N6A 5W9, Canada
World J Gastroenterol 16:232-6. 2010..To understand the demographic characteristics of patients in Southwestern Ontario, Canada with ulcerative colitis (UC) in order to predict disease severity... - Azathioprine or 6-mercaptopurine for induction of remission in Crohn's diseaseNilesh Chande
London Health Sciences Centre Victoria Hospital, Room E1 423A, 800 Commissioners Road East, London, Ontario, Canada, N6A 5W9
Cochrane Database Syst Rev 4:CD000545. 2013..An updated meta-analysis was performed to assess the effectiveness of these drugs for the induction of remission in active Crohn's disease... - Quality of Internet-based information on gastrointestinal diseasesVikram Tangri
Department of Medicine, The University of Western Ontario and London Health Sciences Center, London, Ontario
Can J Gastroenterol 25:93-6. 2011..The Internet is becoming an increasingly common source of health information for patients... - Latent lymphocytic enterocolitis associated with celiac disease manifesting after resection for colon cancer: case report and review of the literatureVikram Tangri
Faculty of Medicine and Dentistry, The University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada
Can J Gastroenterol 22:771-3. 2008..Pathological review of his initial resection specimen demonstrated lymphocytic enterocolitis, indicating a five-year latency in the presentation of this disease...