An Wen Chan

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Empirical evidence for selective reporting of outcomes in randomized trials: comparison of protocols to published articles
    An Wen Chan
    Centre for Statistics in Medicine, Institute of Health Sciences, Headington, Oxford, England
    JAMA 291:2457-65. 2004
  2. pmc Outcome reporting bias in randomized trials funded by the Canadian Institutes of Health Research
    An Wen Chan
    Randomized Controlled Trials Unit, Canadian Institutes of Health Research, Ottawa, Ont
    CMAJ 171:735-40. 2004
  3. ncbi request reprint Assessing clinical trial results
    An Wen Chan
    Science 312:365-6; author reply 365-6. 2006
  4. doi request reprint Increasing value and reducing waste: addressing inaccessible research
    An Wen Chan
    Women s College Research Institute, Department of Medicine, Women s College Hospital, University of Toronto, Toronto, ON, Canada Electronic address
    Lancet 383:257-66. 2014
  5. doi request reprint SPIRIT 2013 statement: defining standard protocol items for clinical trials
    An Wen Chan
    Women s College Research Institute, Women s College Hospital, University of Toronto, 790 Bay Street, Toronto, Ontario M5G 1N8, Canada
    Ann Intern Med 158:200-7. 2013
  6. pmc Compliance of clinical trial registries with the World Health Organization minimum data set: a survey
    Lorenzo P Moja
    Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Trials 10:56. 2009
  7. pmc Research protocols: waiving confidentiality for the greater good
    An Wen Chan
    Randomized Controlled Trials Unit, Canadian Institutes of Health Research, Toronto, Canada
    BMJ 332:1086-9. 2006
  8. pmc Identifying outcome reporting bias in randomised trials on PubMed: review of publications and survey of authors
    An Wen Chan
    University Health Network, Department of Medicine, Suite RFE 3 805, 190 Elizabeth Street, Toronto, ON M5G 2C4, Canada
    BMJ 330:753. 2005
  9. ncbi request reprint Epidemiology and reporting of randomised trials published in PubMed journals
    An Wen Chan
    Department of Medicine, University Health Network Toronto, Canada
    Lancet 365:1159-62. 2005
  10. pmc Investigator experiences with financial conflicts of interest in clinical trials
    Paula A Rochon
    Women s College Research Institute at Women s College Hospital, Toronto, Canada
    Trials 12:9. 2011

Detail Information

Publications24

  1. ncbi request reprint Empirical evidence for selective reporting of outcomes in randomized trials: comparison of protocols to published articles
    An Wen Chan
    Centre for Statistics in Medicine, Institute of Health Sciences, Headington, Oxford, England
    JAMA 291:2457-65. 2004
    ..Selective reporting of outcomes within published studies based on the nature or direction of their results has been widely suspected, but direct evidence of such bias is currently limited to case reports...
  2. pmc Outcome reporting bias in randomized trials funded by the Canadian Institutes of Health Research
    An Wen Chan
    Randomized Controlled Trials Unit, Canadian Institutes of Health Research, Ottawa, Ont
    CMAJ 171:735-40. 2004
    ..We sought to determine whether outcome reporting bias would be present in a cohort of government-funded trials subjected to rigorous peer review...
  3. ncbi request reprint Assessing clinical trial results
    An Wen Chan
    Science 312:365-6; author reply 365-6. 2006
  4. doi request reprint Increasing value and reducing waste: addressing inaccessible research
    An Wen Chan
    Women s College Research Institute, Department of Medicine, Women s College Hospital, University of Toronto, Toronto, ON, Canada Electronic address
    Lancet 383:257-66. 2014
    ....
  5. doi request reprint SPIRIT 2013 statement: defining standard protocol items for clinical trials
    An Wen Chan
    Women s College Research Institute, Women s College Hospital, University of Toronto, 790 Bay Street, Toronto, Ontario M5G 1N8, Canada
    Ann Intern Med 158:200-7. 2013
    ....
  6. pmc Compliance of clinical trial registries with the World Health Organization minimum data set: a survey
    Lorenzo P Moja
    Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Trials 10:56. 2009
    ..The objective is to evaluate registries' and individual trial records' compliance with the 2006 version of the WHO minimum data set...
  7. pmc Research protocols: waiving confidentiality for the greater good
    An Wen Chan
    Randomized Controlled Trials Unit, Canadian Institutes of Health Research, Toronto, Canada
    BMJ 332:1086-9. 2006
  8. pmc Identifying outcome reporting bias in randomised trials on PubMed: review of publications and survey of authors
    An Wen Chan
    University Health Network, Department of Medicine, Suite RFE 3 805, 190 Elizabeth Street, Toronto, ON M5G 2C4, Canada
    BMJ 330:753. 2005
    ..To examine the extent and nature of outcome reporting bias in a broad cohort of published randomised trials...
  9. ncbi request reprint Epidemiology and reporting of randomised trials published in PubMed journals
    An Wen Chan
    Department of Medicine, University Health Network Toronto, Canada
    Lancet 365:1159-62. 2005
    ..The small sample sizes are worrying, and poor reporting of methodological characteristics will prevent reliable quality assessment of many published trials...
  10. pmc Investigator experiences with financial conflicts of interest in clinical trials
    Paula A Rochon
    Women s College Research Institute at Women s College Hospital, Toronto, Canada
    Trials 12:9. 2011
    ..We obtained information from investigators about adherence to practices that minimize the introduction of such bias in their clinical trials experience...
  11. pmc SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials
    An Wen Chan
    Women s College Research Institute at Women s College Hospital, Department of Medicine, University of Toronto, Toronto, Canada M5G 1N8
    BMJ 346:e7586. 2013
    ..Complete documentation of key trial elements can facilitate transparency and protocol review for the benefit of all stakeholders...
  12. ncbi request reprint [Principles of the international registry of protocols and clinical trial results based on health interventions in human beings: Ottawa Declaration (part 1)]
    Karmela Krleza-Jeric
    Canadian Institutes of Health Research, Ottawa, Ontario, Canada
    Rev Panam Salud Publica 19:413-6. 2006
  13. ncbi request reprint [Selective reporting of positive outcomes in randomised trials--secondary publication.. A comparison of protocols with published reports]
    Asbjørn Hróbjartsson
    H S Rigshopitalet, Det Nordiske Cochrane Center, University Health Network Toronto, Department of Medicine
    Ugeskr Laeger 167:3189-91. 2005
    ..Selective reporting of positive outcomes is associated with bias...
  14. pmc National evaluation of policies on individual financial conflicts of interest in Canadian academic health science centers
    Joel Lexchin
    School of Health Policy and Management, York University, Toronto, ON, Canada
    J Gen Intern Med 23:1896-903. 2008
    ..Conflicts of interest (COI) in research are an important emerging topic of investigation and are frequently cited as a serious threat to the integrity of human participant research...
  15. pmc Principles for international registration of protocol information and results from human trials of health related interventions: Ottawa statement (part 1)
    Karmela Krleza-Jeric
    Randomised Controlled Trials Unit, Canadian Institutes of Health Research, Ottawa, 160 Elgin Street, Ottawa ON, K1A 0W9, Canada
    BMJ 330:956-8. 2005
  16. pmc Guidelines for randomized clinical trial protocol content: a systematic review
    Jennifer M Tetzlaff
    Ottawa Methods Centre, Ottawa Hospital Research Institute, Smyth Road, Ottawa, Ontario, K1H 8L6, Canada
    Syst Rev 1:43. 2012
    ..The objective of this study was to systematically identify and review RCT protocol guidelines, to assess their characteristics and methods of development, and to compare recommendations...
  17. pmc Developing a guideline for clinical trial protocol content: Delphi consensus survey
    Jennifer Marie Tetzlaff
    Ottawa Methods Centre, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada
    Trials 13:176. 2012
    ....
  18. pmc Poor reporting of scientific leadership information in clinical trial registers
    Melanie Sekeres
    Kunin Lunenfeld Applied Research Unit, Baycrest, Toronto, Ontario, Canada
    PLoS ONE 3:e1610. 2008
    ..Identifying those scientifically responsible for trial conduct increases accountability. The objective is to examine the proportion of registered clinical trials providing valid scientific leadership information...
  19. pmc Reporting on covariate adjustment in randomised controlled trials before and after revision of the 2001 CONSORT statement: a literature review
    Ly Mee Yu
    Centre for Statistics in Medicine, University of Oxford, Wolfson College Annexe, Oxford, UK
    Trials 11:59. 2010
    ..To evaluate the use and reporting of adjusted analysis in randomised controlled trials (RCTs) and compare the quality of reporting before and after the revision of the CONSORT Statement in 2001...
  20. ncbi request reprint [Constraints on publication rights in industry-initiated clinical trials--secondary publication]
    Peter C Gøtzsche
    H S Rigshospitalet, Det Nordiske Cochrane Center, DK 2100 København Ø
    Ugeskr Laeger 168:2467-9. 2006
    ..These facts were not noted in any of the trial reports. We found similar constraints on publication rights in 44 protocols from 2004. This tight sponsor control over industry-initiated trials should be changed...
  21. pmc Comparison of descriptions of allocation concealment in trial protocols and the published reports: cohort study
    Julie Pildal
    Nordic Cochrane Centre, H S Rigshospitalet, DK 2100 Copenhagen, Denmark
    BMJ 330:1049. 2005
    ....
  22. ncbi request reprint Clinical trial registration: transparency is the watchword
    Ida Sim
    Department of Research Policy and Cooperation, World Health Organization, 1211 Geneva 27, Switzerland
    Lancet 367:1631-3. 2006
  23. ncbi request reprint Constraints on publication rights in industry-initiated clinical trials
    Peter C Gøtzsche
    JAMA 295:1645-6. 2006
  24. pmc Ghost authorship in industry-initiated randomised trials
    Peter C Gøtzsche
    Nordic Cochrane Centre, Copenhagen, Denmark
    PLoS Med 4:e19. 2007
    ..The prevalence and nature of ghost authorship in industry-initiated randomised trials is not known...