Affiliation: University of British Columbia
- Modification by antioxidant supplementation of changes in human lung function associated with air pollutant exposure: a systematic reviewAmir Y Tashakkor
The University of British Columbia, Vancouver, British Columbia, Canada
BMC Public Health 11:532. 2011..This study systematically presents current data on the potential benefits of antioxidant supplementation on lung function outcomes associated with air pollutant exposures in intact humans...
- Glutathione S-transferase M1 (GSTM1) polymorphisms and lung cancer: a literature-based systematic HuGE review and meta-analysisC Carlsten
Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
Am J Epidemiol 167:759-74. 2008..38, 95% CI: 1.24, 1.55), such a genotype did not confer increased risk to Caucasians. More data regarding the predictive value of GSTM1 genetic testing are needed before population-based testing may be reasonably considered...
- Personalized medicine and tobacco-related health disparities: is there a role for genetics?Chris Carlsten
University of British Columbia, Vancouver, Canada
Ann Fam Med 9:366-71. 2011....
- Association between endotoxin and mite allergen exposure with asthma and specific sensitization at age 7 in high-risk childrenChris Carlsten
Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
Pediatr Allergy Immunol 22:320-6. 2011..In high-risk children at age 7, endotoxin levels were associated with decreased sensitization to dog, as well as with decreased asthma...
- Airway hyperresponsiveness to methacholine in 7-year-old children: sensitivity and specificity for pediatric allergist-diagnosed asthmaChris Carlsten
Department of Medicine, Chan Yeung Centre for Occupational and Environmental Respiratory Disease, University of British Columbia, Vancouver, BC
Pediatr Pulmonol 46:175-8. 2011..The operating characteristics of PC(20) values used as cut-offs to define airway hyperresponsiveness, as it informs the diagnosis of asthma in children, are poorly understood. We examine data from a unique cohort to inform this concern...
- Traffic-related air pollution and incident asthma in a high-risk birth cohortChris Carlsten
Department of Medicine, University of British Columbia, Vancouver, Canada
Occup Environ Med 68:291-5. 2011..We aimed to evaluate the hypothesis that the risk of new onset asthma is positively associated with early exposure to traffic-related air pollution in a well-characterised high-risk birth cohort...
- Combined exposure to dog and indoor pollution: incident asthma in a high-risk birth cohortC Carlsten
Vancouver General Hospital The Lung Center, Vancouver, Canada
Eur Respir J 37:324-30. 2011..1 (95% CI 1.1-8.6)). In a high-risk birth cohort, early co-exposure to Can-f1 and NO₂ or ETS increased the risk of incident asthma. Atopy increased the risk of asthma and BHR associated with ETS...
- Indoor allergen exposure, sensitization, and development of asthma in a high-risk birth cohortChris Carlsten
Division of Respirology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
Pediatr Allergy Immunol 21:e740-6. 2010....
- Thrombotic markers in metabolic syndrome subjects exposed to diesel exhaustC Carlsten
Department of Medicine and School of Environmental Health, University of British Columbia, Vancouver, BC, Canada
Inhal Toxicol 20:917-21. 2008..Thus, in a novel study, we were unable to demonstrate a prothrombotic effect of moderate-dose diesel exhaust exposure in a population at risk for cardiovascular disease...
- OX40L blockade and allergen-induced airway responses in subjects with mild asthmaG M Gauvreau
Department of Medicine, McMaster University, Hamilton, ON, Canada
Clin Exp Allergy 44:29-37. 2014..The OX40/OX40L interaction contributes to an optimal T cell response following allergic stimuli and plays an important role in the maintenance and reactivation of memory T effector cells...
- Respiratory disease associated with solid biomass fuel exposure in rural women and children: systematic review and meta-analysisJune Y T Po
Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada
Thorax 66:232-9. 2011..Numerous studies with varying associations between domestic use of solid biomass fuels (wood, dung, crop residue, charcoal) and respiratory diseases have been reported...