P M Campbell
Affiliation: University of Alberta
- Clinical relevance of human leukocyte antigen antibodies in liver, heart, lung and intestine transplantationPatricia Campbell
Department of Medicine and Laboratory Medicine, University of Alberta, Edmonton, Alberta, Canada
Curr Opin Organ Transplant 18:463-9. 2013..Whether to accept or decline an organ if the virtual crossmatch is positive, when to monitor and whether to treat de-novo donor-specific antibody (DSA) posttransplant remain challenging issues for the transplant clinician...
- Pretransplant HLA antibodies are associated with reduced graft survival after clinical islet transplantationP M Campbell
Department of Medicine, Division of Nephrology and Immunology, University of Alberta, Capital Health, Edmonton, Alberta, Canada
Am J Transplant 7:1242-8. 2007....
- De novo donor-specific antibody at the time of kidney transplant biopsy associates with microvascular pathology and late graft failureL G Hidalgo
Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada
Am J Transplant 9:2532-41. 2009..We propose careful assessment of de novo DSA, particularly against class II, be performed in all late kidney transplant biopsies...
- NK cell transcripts and NK cells in kidney biopsies from patients with donor-specific antibodies: evidence for NK cell involvement in antibody-mediated rejectionL G Hidalgo
Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada
Am J Transplant 10:1812-22. 2010..Thus, the strategy of using DSASTs in the biopsy to identify mechanism-related transcripts in biopsies from patients with clinical phenotypes indicates the selective involvement of NK cells in ABMR...
- High risk of sensitization after failed islet transplantationP M Campbell
Department of Medicine, and Histocompatability Laboratory, University of Alberta, Capital Health, Edmonton, Alberta, Canada
Am J Transplant 7:2311-7. 2007..This may negatively impact the ability of these individuals to undergo further islet, pancreas or kidney transplantation and should be discussed upfront during evaluation of candidates for islet transplantation...
- Antibody-mediated microcirculation injury is the major cause of late kidney transplant failureG Einecke
Alberta Transplant Applied Genomics Centre, Department of Medicine, Division of Nephrology and Transplant Immunology, University of Alberta, Edmonton, AB, Canada
Am J Transplant 9:2520-31. 2009..The major cause of late kidney transplant failure is antibody-mediated microcirculation injury, but detection of this phenotype requires new diagnostic criteria...
- Transplant glomerulopathy, late antibody-mediated rejection and the ABCD tetrad in kidney allograft biopsies for causeB Sis
Laboratory Medicine and Pathology, and Medicine, Division of Nephrology and Transplantation Immunology, University of Alberta, Edmonton, AB, Canada
Am J Transplant 7:1743-52. 2007..The remaining 27%, mostly BD, may be a different disease or a stage in which A and C are undetectable...
- Absence of donor-specific anti-HLA antibodies after ABO-incompatible heart transplantation in infancy: altered immunity or age?S Urschel
Department of Pediatrics, Cardiac Transplant Research, University of Alberta, Edmonton, Alberta, Canada
Am J Transplant 10:149-56. 2010..This difference was present also when comparing only children transplanted below 2 years of age. Therefore, tolerance toward the donor blood group appears to be associated with an altered response to HLA beyond age-related effects...
- Banff '05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN')K Solez
University of Alberta, Edmonton, Alberta, Canada
Am J Transplant 7:518-26. 2007..Participation of B cells in allograft rejection and genomics markers of rejection were also major subjects addressed by the conference...